A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases

mBio

Volumn 5, Issue 4, 2014, Pages

  Mousnier, Aurélie ^a,d   Schroeder, Gunnar N ^a   Stoneham, Charlotte A ^a,e   So, Ernest C ^a   Garnett, James A ^a   Yu, L ^b   Matthews, Steve J ^a   Choudhary, Jyoti S ^b   Hartland, Elizabeth L ^c   Frankel, Gad ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BIRA PROTEIN; EFFECTOR PIEE PROTEIN; HEXAHISTIDINE; NITRILOTRIACETIC ACID; RAB GTPASE 10; RAB GTPASE 1A; RAB GTPASE 1B; RAB GTPASE 2A; RAB GTPASE 5C; RAB GTPASE 6A; RAB GTPASE 7; RAB PROTEIN; STREPTAVIDIN; UNCLASSIFIED DRUG; HIS-HIS-HIS-HIS-HIS-HIS; HISTIDINE; MEMBRANE PROTEIN; OLIGOPEPTIDE;

A549 CELL LINE; AFFINITY CHROMATOGRAPHY; ARTICLE; BIOTINYLATION; CELL VACUOLE; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERACTOME; LEGIONELLA PNEUMOPHILA; MASS SPECTROMETRY; NONHUMAN; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN TARGETING; SMOOTH ENDOPLASMIC RETICULUM; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENDOPLASMIC RETICULUM; GENETICS; HELA CELL LINE; HOST PATHOGEN INTERACTION; INTRACELLULAR MEMBRANE; METABOLISM; MICROBIOLOGY; PROCEDURES; PROTEIN TRANSPORT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE;

LEGIONELLA PNEUMOPHILA;

ANIMALS; BACTERIAL PROTEINS; CELL LINE, TUMOR; CHROMATOGRAPHY, AFFINITY; ENDOPLASMIC RETICULUM; HELA CELLS; HISTIDINE; HOST-PATHOGEN INTERACTIONS; HUMANS; INTRACELLULAR MEMBRANES; LEGIONELLA PNEUMOPHILA; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; VACUOLES;

EID: 84908281268     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01148-14     Document Type: Article

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