The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway

Toxicology and Applied Pharmacology

Volumn 280, Issue 3, 2014, Pages 502-510

  Yu, Haitao ^a   Du, Yuxuan ^a   Zhang, Xulong ^a   Sun, Ying ^a   Li, Shentao ^a   Dou, Yunpeng ^a   Li, Zhanguo ^b   Yuan, Huihui ^a   Zhao, Wenming ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Aryl hydrocarbon receptor (Ahr); Differentiation; ERK signaling pathway; Osteoblasts; Proliferation; Rheumatoid arthritis (RA)

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALKALINE PHOSPHATASE; AROMATIC HYDROCARBON RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; 2-METHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID (2-METHYL-4-O-TOLYLAZOPHENYL)AMIDE; AZO COMPOUND; PYRAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE EROSION; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; OSTEOBLAST; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE; CELL LINE; CYTOLOGY; DBA MOUSE; EXPERIMENTAL ARTHRITIS; GERMFREE ANIMAL; METABOLISM; NONPARAMETRIC TEST; PHYSIOLOGY;

ALKALINE PHOSPHATASE; ANIMALS; ARTHRITIS, EXPERIMENTAL; AZO COMPOUNDS; BLOTTING, WESTERN; BONE AND BONES; BONE DENSITY; CELL LINE; CELL PROLIFERATION; IMMUNOHISTOCHEMISTRY; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED DBA; OSTEOBLASTS; PYRAZOLES; RECEPTORS, ARYL HYDROCARBON; SPECIFIC PATHOGEN-FREE ORGANISMS; STATISTICS, NONPARAMETRIC; TETRACHLORODIBENZODIOXIN;

EID: 84908280854     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.08.025     Document Type: Article

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