Impact of bone harvesting techniques on cell viability and the release of growth factors of autografts

Clinical Implant Dentistry and Related Research

Volumn 15, Issue 4, 2013, Pages 481-489

  Miron, Richard J ^a   Gruber, Reinhard ^b   Hedbom, Erik ^c   Saulacic, Nikola ^a   Zhang, Yufeng ^a   Sculean, Anton ^a   Bosshardt, Dieter D ^a   Buser, Daniel ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Autogenous bone; Bone dust; Bone graft; Bone mill; Bone particles; Bone scraper; Bone slurry; Osteocyte; Osteoinduction; Piezosurgery

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; CULTURE MEDIUM; MITOGENIC AGENT; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A;

ANIMAL; AUTOGRAFT; BONE; BONE DEVELOPMENT; BONE TRANSPLANTATION; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; COMPARATIVE STUDY; CULTURE MEDIUM; CYTOLOGY; DEVICES; METABOLISM; MINIPIG; OSTEOBLAST; OSTEOLYSIS; OSTEOTOMY; PHYSIOLOGY; PIEZOSURGERY; PROCEDURES; SURGERY; SWINE; TRANSPLANTATION;

ANIMALS; AUTOGRAFTS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; BONE RESORPTION; BONE TRANSPLANTATION; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CULTURE MEDIA, CONDITIONED; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGENS; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OSTEOPROTEGERIN; OSTEOTOMY; PIEZOSURGERY; RANK LIGAND; SWINE; SWINE, MINIATURE; TISSUE AND ORGAN HARVESTING; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84881238895     PISSN: 15230899     EISSN: 17088208     Source Type: Journal    
DOI: 10.1111/j.1708-8208.2012.00440.x     Document Type: Article

References (32)

1. Klijn RJ, Meijer GJ, Bronkhorst EM, Jansen JA. Sinus floor augmentation surgery using autologous bone grafts from various donor sites: a meta-analysis of the total bone volume. Tissue Eng Part B Rev 2010; 16:295-303.
2. Sittitavornwong S, Gutta R. Bone graft harvesting from regional sites. Oral Maxillofac Surg Clin North Am 2010; 22:317-330, v-vi.
3. Zouhary KJ. Bone graft harvesting from distant sites: concepts and techniques. Oral Maxillofac Surg Clin North Am 2010; 22:301-316, v.
4. Giannoudis PV, Dinopoulos H, Tsiridis E. Bone substitutes: an update. Injury 2005; 36(Suppl 3):S20-S27.
5. Khan SN, Cammisa FP Jr, Sandhu HS, Diwan AD, Girardi FP, Lane JM. The biology of bone grafting. J Am Acad Orthop Surg 2005; 13:77-86.
6. Gruber R, Kandler B, Holzmann P, etal. Bone marrow stromal cells can provide a local environment that favors migration and formation of tubular structures of endothelial cells. Tissue Eng 2005; 11:896-903.
7. Saleh FA, Whyte M, Ashton P, Genever PG. Regulation of mesenchymal stem cell activity by endothelial cells. Stem Cells Dev 2011; 20:391-403.
8. Heino TJ, Hentunen TA, Vaananen HK. Conditioned medium from osteocytes stimulates the proliferation of bone marrow mesenchymal stem cells and their differentiation into osteoblasts. Exp Cell Res 2004; 294:458-468.
9. Springer IN, Terheyden H, Geiss S, Harle F, Hedderich J, Acil Y. Particulated bone grafts - effectiveness of bone cell supply. Clin Oral Implants Res 2004; 15:205-212.
10. Pradel W, Tenbieg P, Lauer G. Influence of harvesting technique and donor site location on in vitro growth of osteoblastlike cells from facial bone. Int J Oral Maxillofac Implants 2005; 20:860-866.
11. Gruber R, Baron M, Busenlechner D, Kandler B, Fuerst G, Watzek G. Proliferation and osteogenic differentiation of cells from cortical bone cylinders, bone particles from mill, and drilling dust. J Oral Maxillofac Surg 2005; 63:238-243.
12. Miron RJ, Hedbom E, Saulacic N, etal. Osteogenic potential of autogenous bone grafts harvested with four different surgical techniques. J Dent Res 2011; 90:1428-1433.
13. Ryoo HM, Lee MH, Kim YJ. Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells. Gene 2006; 366:51-57.
14. Soderberg SS, Karlsson G, Karlsson S. Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling. Ann N Y Acad Sci 2009; 1176:55-69.
15. Aybar B, Emes Y, Atalay B, etal. Effects of bone morphogenetic protein on neonatal rat calvarial osteoblast-like cells: an in vitro study. J Biomed Mater Res A 2008; 86:560-568.
16. Bosetti M, Boccafoschi F, Leigheb M, Cannas MF. Effect of different growth factors on human osteoblasts activities: a possible application in bone regeneration for tissue engineering. Biomol Eng 2007; 24:613-618.
17. Fang H, Yang X, Chen A, Luo Y. Effect of rhBMP-2 and osteogenic revulsants on proliferation and differentiation of bone marrow stromal cells in rats. J Huazhong Univ Sci Technolog Med Sci 2007; 27:561-563.
18. van der Zande M, Walboomers XF, Briest A, Springer M, Alava JI, Jansen JA. The effect of combined application of TGFbeta-1, BMP-2, and COLLOSS E on the development of bone marrow derived osteoblast-like cells in vitro. J Biomed Mater Res A 2008; 86:788-795.
19. Zheng Y, Wu G, Zhao J, Wang L, Sun P, Gu Z. rhBMP2/7 heterodimer: an osteoblastogenesis inducer of not higher potency but lower effective concentration compared with rhBMP2 and rhBMP7 homodimers. Tissue Eng Part A 2010; 16:879-887.
20. Lazarus A, Keshet E. Vascular endothelial growth factor and vascular homeostasis. Proc Am Thorac Soc 2011; 8:508-511.
21. Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature 2003; 423:337-342.
22. Miron RJ, Oates CJ, Molenberg A, Dard M, Hamilton DW. The effect of enamel matrix proteins on the spreading, proliferation and differentiation of osteoblasts cultured on titanium surfaces. Biomaterials 2010; 31:449-460.
23. Robey PG, Termine JD. Human bone cells in vitro. Calcif Tissue Int 1985; 37:453-460.
24. Bianco P, Robey PG, Saggio I, Riminucci M. "Mesenchymal" stem cells in human bone marrow (skeletal stem cells): a critical discussion of their nature, identity, and significance in incurable skeletal disease. Hum Gene Ther 2010; 21:1057-1066.
25. Robling AG, Turner CH. Mechanical signaling for bone modeling and remodeling. Crit Rev Eukaryot Gene Expr 2009; 19:319-338.
26. Bonewald LF. The amazing osteocyte. J Bone Miner Res 2011; 26:229-238.
27. Nakashima T, Hayashi M, Fukunaga T, etal. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med 2011; 17:1231-1234.
28. Fonseca RJ, Clark PJ, Burkes EJ Jr, Baker RD. Revascularization and healing of onlay particulate autologous bone grafts in primates. J Oral Surg 1980; 38:572-577.
29. Ullmark G. Bigger size and defatting of bone chips will increase cup stability. Arch Orthop Trauma Surg 2000; 120:445-447.
30. Kogianni G, Mann V, Noble BS. Apoptotic bodies convey activity capable of initiating osteoclastogenesis and localized bone destruction. J Bone Miner Res 2008; 23:915-927.
31. Gruber R, Kandler B, Agis H, Fischer MB, Watzek G. Bone cell responsiveness to growth and differentiation factors under hypoxia in vitro. Int J Oral Maxillofac Implants 2008; 23:417-426.
32. Gruber R, Kandler B, Fischer MB, Watzek G. Osteogenic differentiation induced by bone morphogenetic proteins can be suppressed by platelet-released supernatant in vitro. Clin Oral Implants Res 2006; 17:188-193.