A comprehensive immunohistochemical examination of the distribution of the fat-burning protein irisin in biological tissues

Peptides

Volumn 61, Issue , 2014, Pages 130-136

  Aydin, Suleyman ^a   Kuloglu, Tuncay ^a   Aydin, Suna ^a,b   Kalayci, Mehmet ^c   Yilmaz, Musa ^a   Cakmak, Tolga ^d   Albayrak, Serdal ^b   Gungor, Sami ^e   Colakoglu, Neriman ^a   Ozercan, Ibrahim Hanifi ^a  

^a FIRAT UNIVERSITY   (Turkey)

^b Department of Histology and Embryology Medical School Firat University ^*  (Turkey)

^c Elazig Training and Research Hospital   (Turkey)

^d Ercis State Hospital   (Turkey)

^e Department of Gynecology Private Medical Hospital   (Turkey)

Author keywords

Brain; Fetal skeletal muscle; Irisin; Spleen; Testis

Indexed keywords

IRISIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; FIBRONECTIN; FNDC5 PROTEIN, HUMAN; FNDC5 PROTEIN, RAT;

ADULT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BROWN ADIPOSE TISSUE; CELL SPREADING; CONTROLLED STUDY; ENDOMYSIUM; ENDONEURIUM; EPIDIDYMIS; FETUS; GLIA CELL; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KUPFFER CELL; LEYDIG CELL; LIPID METABOLISM; LIVER CELL; MALE; NERVE FIBER; NONHUMAN; PANCREAS; PANCREAS ISLET; PERIMYSIUM; PERINEURIUM; PERIPHERAL NERVE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SARCOPLASM; SEBACEOUS GLAND; SEMINIFEROUS TUBULE; SKELETAL MUSCLE; SPERMATOCYTE; STOMACH PARIETAL CELL; TESTIS; ANIMAL; ANTIBODY SPECIFICITY; ENERGY METABOLISM; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADULT; ANIMALS; ENERGY METABOLISM; FIBRONECTINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; ORGAN SPECIFICITY; RATS;

EID: 84908269275     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2014.09.014     Document Type: Article

References (26)

1. S. Aydin Three new players in energy regulation: preptin, adropin and irisin Peptides 56 2014 94 110
2. S. Aydin, S. Aydin, M.A. Kobat, M. Kalayci, M.N. Eren, and M. Yilmaz Decreased saliva/serum irisin concentrations in the acute myocardial infarction promising for being a new candidate biomarker for diagnosis of this pathology Peptides 56 2014 141 145
3. S. Aydin, S. Aydin, T. Kuloglu, M. Yilmaz, M. Kalayci, and I. Sahin Alterations of irisin concentrations in saliva and serum of obese and normal-weight subjects, before and after 45 min of a Turkish bath or running Peptides 50 2013 13 18
4. S. Aydin, T. Kuloglu, and S. Aydin Copeptin, adropin and irisin concentrations in breast milk and plasma of healthy women and those with gestational diabetes mellitus Peptides 47 2013 66 70
5. S. Aydin, T. Kuloglu, S. Aydin, M.N. Eren, A. Celik, and M. Yilmaz Cardiac, skeletal muscle and serum irisin responses to with or without water exercise in young and old male rats: cardiac muscle produces more irisin than skeletal muscle Peptides 52C 2013 68 73
6. P. Boström, J. Wu, M.P. Jedrychowski, A. Korde, L. Ye, and J.C. Lo A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Nature 481 2012 463 468
7. J. Brenmoehl, E. Albrecht, K. Komolka, L. Schering, M. Langhammer, and A. Hoeflich Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise Int J Biol Sci 10 2014 338 349
8. J.H. Carter, L.E. Douglass, J.A. Deddens, B.M. Colligan, T.R. Bhatt, and J.O. Pemberton Pak-1 expression increases with progression of colorectal carcinomas to metastasis Clin Cancer Res 10 2004 3448 3456
9. J.I. Castillo-Quan From white to brown fat through the PGC-1α dependent myokine irisin: implications for diabetesand obesity Dis Model Mech 5 2012 293 295
10. Y.K. Choi, M.K. Kim, K.H. Bae, H.A. Seo, J.Y. Jeong, and W.K. Lee Serum irisin levels in new-onset type 2 diabetes Diabetes Res Clin Pract 100 2013 96 101
11. S.L. Dun, R.M. Lyu, Y.H. Chen, J.K. Chang, J.J. Luo, and N.J. Dun Irisin-immunoreactivity in neural and non-neural cells of the rodent Neuroscience 240 2013 155 162
12. H.P. Erickson Irisin and FNDC5 in retrospect: an exercise hormone or a transmembrane receptor? Adipocyte 2 2013 289 293
13. T. Hofmann, U. Elbelt, and A. Stengel Irisin as a muscle-derived hormone stimulating thermogenesis - a critical update Peptides 54C 2014 89 100
14. S.M. Hsu, L. Raine, and H. Fanger Use of avidin-biotin-peroxidase complex (ABC) inimmunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures J Histochem Cytochem 29 1981 577 580
15. J.Y. Huh, G. Panagiotou, V. Mougios, M. Brinkoetter, M.T. Vamvini, and B.E. Schneider FNDC5 and irisin in humans. I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise Metabolism 61 2012 1725 1738
16. H.G. Joost, L.M. Williams, W. Langhans, and C. Diéguez Effects of obestatin on energy balance and growth hormone secretion in rodents Endocrinology 148 2007 21 26
17. K. Komolka, E. Albrecht, L. Schering, J. Brenmoehl, A. Hoeflich, and S. Maak Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle? PLoS ONE 9 2014 e88060
18. T. Kuloglu, S. Aydin, M.N. Eren, M. Yilmaz, I. Sahin, and M. Kalayci Irisin: a potentially candidate marker for myocardial infarction Peptides 55 2014 85 91
19. T. Kurdiova, M. Balaz, M. Vician, D. Maderova, M. Vlcek, and L. Valkovic Are skeletal muscle & adipose tissue Fndc5 gene expression and irisin release affected by obesity, diabetes and exercise? In vivo & in vitro studies J Physiol 592 2014 1091 1107
20. T. Kurdiova, M. Balaz, A. Mayer, D. Maderova, V. Belan, and C. Wolfrum Exercise-mimicking treatment fails to increase Fndc5 mRNA & Irisin secretion in primary human myotubes Peptides 56 2014 1 7
21. J.M. Moreno-Navarrete, F. Ortega, M. Serrano, E. Guerra, G. Pardo, and F. Tinahones Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance J Clin Endocrinol Metab 98 2013 E769 E778
22. M.K. Piya, A.L. Harte, K. Sivakumar, G. Tripathi, P.D. Voyias, and S. James The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers and gestational diabetes Am J Physiol Endocrinol Metab 306 2014 E512 E518
23. A. Roca-Rivada, C. Castelao, L.L. Senin, M.O. Landrove, J. Baltar, and C. Belén FNDC5/irisin is not only a myokine but also an adipokine PLoS ONE 8 2013 e60563
24. F. Romani, A. Lanzone, A. Tropea, A. Familiari, E. Scarinci, and M. Sali In vitro effect of unacylated ghrelin and obestatin on human luteal cell function Fertil Steril 97 2012 991 996
25. I. Sahin, S. Aydin, Y. Ozkan, A.F. Dagli, K.O. Akin, and S.P. Guzel Diet-induced obesity suppresses ghrelin in rat gastrointestinal tract and serum Mol Cell Biochem 355 2011 299 308
26. F. Sanchis-Gomar, R. Alis, H. Pareja-Galeano, M. Romagnoli, and C. Perez-Quilis Inconsistency in circulating irisin levels: what is really happening? Horm Metab Res 46 2014 591 596