Increased serum and urinary MicroRNAs in children with idiopathic nephrotic syndrome

Clinical Chemistry

Volumn 59, Issue 4, 2013, Pages 658-666

  Luo, Yang ^a   Wang, Cheng ^a   Chen, Xi ^a   Zhong, Tianying ^b   Cai, Xiaoyi ^a   Chen, Sidi ^c   Shi, Yonghui ^a   Hu, Jing ^a   Guan, Xiaocui ^a   Xia, Zhengkun ^a,d   Wang, Junjun ^a,d   Zen, Ke ^a   Zhang, Chen Yu ^a   Zhang, Chunni ^a,d  

^a NANJING UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c MicroMedMark Biotech Co Ltd   (China)

^d JINLING HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; MICRORNA; MICRORNA 150; MICRORNA 151; MICRORNA 191; MICRORNA 19B; MICRORNA 30A; PREDNISONE; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; BLOOD LEVEL; CHILD; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFANT; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; PRESCHOOL CHILD; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK; RNA ANALYSIS; SCHOOL CHILD; URINE LEVEL;

ADOLESCENT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; COHORT STUDIES; HUMANS; MICRORNAS; NEPHROTIC SYNDROME; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROC CURVE;

EID: 84875826816     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2012.195297     Document Type: Article

References (36)

1. Bagga A, Mantan M. Nephrotic syndrome in children. Indian J Med Res 2005;122:13-28.
2. Eddy AA, Symons JM. Nephrotic syndrome in childhood. Lancet 2003;362:629 -39.
3. Li H, Wu J, Niu D, Shi Y, Zhang C, Wang J. The level of native and oxidized lipoprotein(a) in children with nephrotic syndrome. Clin Biochem 2012;45:101-5.
4. Boute N, Gribouval O, Roselli S, Benessy F, Lee H, Fuchshuber A, et al. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat Genet 2000;24:349 -54.
5. Abeyagunawardena AS. Treatment of steroid sensitive nephrotic syndrome. Indian J Pediatr 2005; 72:763-9.
6. Tarshish P, Tobin JN, Bernstein J, Edelmann CM Jr. Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children. J Am Soc Nephrol 1997;8:769 -76.
7. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2003;116:281-97.
8. Rosenfeld N, Aharonov R, Meiri E, Rosenwald S, Spector Y, Zepeniuk M, et al. MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol 2008;26:462-9.
9. Chen X, Ba Y, Ma LJ, Cai X, Yin Y, Wang KH, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008;18:997-1006.
10. Hu Z, Chen X, Zhao Y, Tian T, Jin G, Shu Y, et al. Serum microRNA expression signatures identified in a genome-wide profiling predict survival of non-small-cell lung cancer. J Clin Oncol 2010;28: 1721-6.
11. Zhang C, Wang C, Chen X, Yang C, Li K, Wang J, et al. Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin Chem 2010;56:1871-9.
12. Wang C, Yang C, Chen X, Yao B, Zhu C, Li L, et al. Altered profile of seminal plasma microRNAs in the molecular diagnosis of male infertility. Clin Chem 2011;57:1722-31.
13. Liu R, Chen X, Du Y, Yao W, Shen L, Wang C, et al. Serum microRNA expression profile as a biomarker in the diagnosis and prognosis of pancreatic cancer. Clin Chem 2012;58:610-8.
14. Yang C, Wang C, Chen X, Chen S, Zhang Y, Zhi F, et al. Identification of seven serum microRNAs from a genome-wide serum miRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas. Int J Cancer 2013;132:116-27.
15. Weber JA, Baxter DH, Zhang S, Huang DY, Huang KH, Lee MJ, et al. The microRNA spectrum in 12 body fluids. Clin Chem 2012;56:1733-41.
16. Devaux Y, Vausort M, Goretti E, Nazarov PV, Azuaje F, Gilson G, et al. Use of circulating microRNAs to diagnose acute myocardial infarction. Clin Chem 2012;58:559-67.
17. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadanyan EL, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 2008; 105:10513-8.
18. Palacin M, Reguero JR, Martin M, Diaz Molina B, Moris C, Alvarez V, et al. Profile of microRNAs differentially produced in hearts from patients with hypertrophic cardiomyopathy and sarcomeric mutations. Clin Chem 2011;57:1614-6.
19. Chen X, Liang H, Zhang J, Zen K, Zhang CY. Horizontal transfer of microRNAs: molecular mechanisms and clinical applications. Protein Cell 2012;3:28 -37.
20. Wang G, Tam L, Li E, Kwan B, Chow K, Luk C, et al. Serum and urinary free microRNA level in patients with systemic lupus erythematosus. Lupus 2011;20:493-500.
21. Wang G, Kwan BC, Lai FM, Chow KM, Li PK, Szeto CC. Elevated levels of miR-146a and miR- 155 in kidney biopsy and urine from patients with IgA nephropathy. Dis Markers 2011;30:171-9.
22. Wang G, Kwan BC, Lai FM, Chow KM, Li PK, Szeto CC. Expression of microRNAs in the urinary sediment of patients with IgA nephropathy. J Am Soc Nephrol 2012;23:765-6.
23. Lorenzen JM, Kielstein JT, Hafer C, Gupta SK, Kümpers P, Faulhaber-Walter R, et al. Circulating miR-210 predicts survival in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol 2011;6:1540-6.
24. Neal CS, Michael MZ, Pimlott LK, Yong TY, Li JYZ, Gleadle JM. Circulating microRNA expression is reduced in chronic kidney disease. Nephrol Dial Transpl 2011;26:3794-802.
25. International Study of Kidney Disease in Children. The primary nephritic syndrome in children. Identification of patients with minimal change nephritic syndrome from initial response to prednisone. A report of the International Study of Kidney Disease in Children. J Pediatr 1981;98:561-4.
26. Mathieson PW. Update on the podocyte. Curr Opin Nephrol Hypertens 2009;18:206 -11.
27. Shi S, Yu L, Chiu C, Sun Y, Chen J, Khitrov G, et al. Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol 2008;19:2159-69.
28. Zhdanova O, Srivastava S, Di L, Li Z, Tchelebi L, Dworkin S, et al. The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy. Kidney Int 2011;80: 719-30.
29. Harvey SJ, Jarad G, Cunningham J, Goldberg S, Schermer B, Harfe BD, et al. Podocyte-specific deletion of Dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol 2008;19:2150-8.
30. Agrawal R, Tran U, Wessely O. The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development 2009;136:3927-36.
31. Shalhoub RJ. Pathogenesis of lipoid nephrosis: a disorder of T-cell function. Lancet 1974;2:556-60.
32. Brenu EW, Ashton KJ, van Driel M, Staines DR, Peterson D, Atkinson GM, et al. Cytotoxic lymphocyte microRNAs as prospective biomarkers for chronic fatigue syndrome/myalgic encephalomyelitis. J Affect Disord 2012;141:261-9.
33. Ghisi M, Corradin A, Basso K, Frasson C, Serafin V, Mukherjee S, et al. Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150. Blood 2011;117: 7053-62.
34. Jiang S, Li C, Olive V, Lykken E, Feng F, Sevilla J, et al. Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. Blood 2011;118:5487-97.
35. Banaszak B, Banaszak P. The increasing incidence of initial steroid resistance in childhood nephritic syndrome. Pediatr Nephrol 2012;27:927-32.
36. Hara M, Yanagihara T, Kihara I. Cumulative expression of urinary podocytes reflects disease progression in IgA nephropathy Schönlein- Henoch purpura nephritis. Clin J Am Soc Nephrol 2007;2:231-8.