Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication

Science

Volumn 346, Issue 6208, 2014, Pages

  Maric, Marija ^a,b   Maculins, Timurs ^b,c   De Piccoli, Giacomo ^b,d   Labib, Karim ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

^d UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CDC48 PROTEIN; CMG HELICASE; DNA HELICASE; DNA TOPOISOMERASE; FUNGAL DNA; HELICASE; HYDROXYUREA; MINICHROMOSOME MAINTENANCE PROTEIN 7; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CDC45 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; DIA2 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; F BOX PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN; NUCLEAR PROTEIN; PRP8 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN;

CELL ORGANELLE; CHROMOSOME; DNA; ENZYME ACTIVITY; EUKARYOTE; YEAST;

ARTICLE; CELL CYCLE S PHASE; CHROMOSOME REPLICATION; CONTROLLED STUDY; DISSOLUTION; DNA CONTENT; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PHENOTYPE; PROTEIN PROCESSING; S PHASE CELL CYCLE CHECKPOINT; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; YEAST; YEAST CELL; GENETICS; METABOLISM;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE PROTEINS; DNA REPLICATION; DNA-BINDING PROTEINS; F-BOX PROTEINS; MINICHROMOSOME MAINTENANCE PROTEINS; NUCLEAR PROTEINS; RIBONUCLEOPROTEIN, U4-U6 SMALL NUCLEAR; RIBONUCLEOPROTEIN, U5 SMALL NUCLEAR; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 84908248970     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1253596     Document Type: Article

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