Infection of cultured human endothelial cells by Legionella pneumophila

PLoS ONE

Volumn 3, Issue 4, 2008, Pages

  Chiaraviglio, Lucius ^a   Brown, Daniel A ^a   Kirby, James E ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL STRAIN; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; ENDOCYTOSIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; LUNG INJURY; PHAGOSOME; UMBILICAL VEIN; BACTERIAL INFECTION; CELL DIVISION; CYTOLOGY; ENDOPLASMIC RETICULUM; MEMBRANE FUSION; MICROBIOLOGY; PHYSIOLOGY; ULTRASTRUCTURE;

LEGIONELLA PNEUMOPHILA; NEGIBACTERIA;

BACTERIAL INFECTIONS; CELL DIVISION; CELLS, CULTURED; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; HUMANS; LEGIONELLA PNEUMOPHILA; MEMBRANE FUSION; PHAGOSOMES;

EID: 44349136839     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002012     Document Type: Article

References (35)

1. Stout JE, Yu VL (1997) Legionellosis. N Engl J Med 337: 682-687.
2. Horwitz MA, Silverstein SC (1980) Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest 66: 441-450.
3. King CH, Fields BS, Shotts EB Jr., White EH (1991) Effects of cytochalasin D and methylamine on intracellular growth of Legionella pneumophila in amoebae and human monocyte-like cells. Infect Immun 59: 758-763.
4. Newsome AL, Baker RL, Miller RD, Arnold RR (1985) Interactions between Naegleria fowleri and Legionella pneumophila. Infect Immun 50: 449-452.
5. Horwitz MA (1983) The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome Fusion in human monocytes.J Exp Med 158: 2108-2126.
6. Roy CR, Tilney LG (2002) The road less traveled: transport of Legionella to the endoplasmic reticulum. J Cell Biol 158: 415-419.
7. Segal G, Purcell M, Shuman HA (1998) Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome. Proc Natl Acad Sci U S A 95: 1669-1674.
8. Segal G, Shuman HA (1997) Characterization of a new region required for macrophage killing by Legionella pneumophila. Infect Immun 65: 5057-5066.
9. Vogel JP, Andrews HL, Wong SK, Isberg RR (1998) Conjugative transfer by the virulence system of Legionella pneumophda. Science 279: 873-876.
10. Nash TW, Libby DM, Horwitz MA (1984) Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macropbages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest 74: 771-782.
11. Mody CH, Paine R 3rd, Shahrabadi MS, Simon RH, Pearlman E, et al. (1993) Legionella pneumophila replicates within rat alveolar epithelial cells. J Infect Dis 167: 1138-1145.
12. Gao LY, Stone BJ, Brieland JK, Abu Kwaik Y (1998) Different fates of Legionella pneumophila pmi and mil mutants within macrophages and alveolar epithelial cells. Microb Pathog 25: 291-306.
13. Cianciotto NP, Stamos JK, Kamp DW (1995) Infectivity of Legionella pneumophila mip mutant for alveolar epithelial cells. Curr Microbiol 30: 247-250.
14. Maruta K, Miyamoto H, Hamada T, Ogawa M, Taniguchi H, et al. (1998) Entry and intracellular growth of Legionella dumoffii in alveolar epithelial cells. Am J Respir Crit Care Med 157: 1967-1974.
15. Evans CP, Winn WC Jr. (1981) Extrathoracic localization of Legionella pneumophila in Legionnaires' pneumonia. Am J Clin Pathol 76: 813-815.
16. Bricland J, Freeman P, Kunkel R, Chrisp C, Hurley M, et al. (1994) Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J mice. A routine model of human Legionnaires' disease. Am J Pathol 145: 1537-1546.
17. Berger KH, Isberg RR (1993) Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol Microbiol 7: 7-19.
18. Isberg RR (1991) Discrimination between intracellular uptake and surface adhesion of bacterial pathogens. Science 252: 934-938.
19. Kirby JE, Vogel JP, Andrews HL, Isberg RR (1998) Evidence for pore-forming ability by Legionella pneumophila. Mol Microbiol 27: 323-336.
20. Andrews HL, Vogel JP, Isberg RR (1998) Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway. Infect Immun 66: 950-958.
21. Khelef N, Shuman HA, Maxfield FR (2001) Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway. Infect Immun 69: 5157-5161.
22. Watarai M, Derre I, Kirby J, Growney JD, Dietrich WF, et al. (2001) Legionella pneumophila is internalized by a macropinocytotic, uptake pathway controlled by the Dot/Icm system and the mouse Lgn1 locus. J Exp Med 194: 1081-1096.
23. Marra A, Blander SJ, Horwitz MA, Shuman HA (1992) Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc Natl Arad Sci U S A 89: 9607-9611.
24. Chi JT, Chang NY, Haraldsen G, Jahnsen FL, Troyanskaya OG, et al. (2003) Endothelail cell diversity revealed by global expression profiling. Proc Natl Acad Sci U S A 100: 10623-10628.
25. Fabbi M, Pastoris MC, Scanziani E, Magnino S, Di Matteo L (1998) Epidemiological and environmental investigations of Legionella pneumophila infection in cattle and case report of fatal pneumonia in a calf. J Clin Microbiol 36: 1942-1947.
26. Horwitz MA (1983) Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med 158: 1319-1331.
27. Abu Kwaik Y (1996) The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum. Appl Environ Microbiol 62: 2022-2028.
28. Husmann LK, Johnson W (1994) Cytotoxicity of extracellular Legionella pneumophila. Infect Immun 62: 2111-2114.
29. Marruchella A, Franco C (2003) Severe alveolar haemorrhage in legionella pneumonia. Sarcoidosis Vase Diffuse Lung Dis 20: 77.
30. Similar KM, Pearce MJ (2004) Diffuse alveolar hemorrhage due to Legionella pneumonia. Sarcoidosis Vasc Diffuse Lung Dis 21: 158-159.
31. Chastre J, Raghut G, Soler P, Brun P, Basset F, et al. (1987) Pulmonary fibrosis following pneumonia due to acute Legionnaires' disease. Clinical, ultrastructural, and immunofluorescent study. Chest 91: 57-62.
32. Massey R, Kumar P, Pepper JR (2003) Innocent victim of a localised outbreak: legionella endocarditis. Heart 89: 16e-.
33. Tompkins LS, Roessler BJ, Redd SC, Markowitz LE, Cohen ML (1988) Legionella, prosthetic-valve endocarditis. N Engl J Med 318: 530-535.
34. McCabe RE, Baldwin JC, McGregor CA, Miller DC, Vosti KL (19M) Prosthetic valve endocarditis caused by Legionella pneumophila. Ann Intern Med 100: 525-527.
35. Swanson MS, Isberg RR (1996) Identification of Legionella pneumophila mutants that have aberrant intracellular fates. Infect Immun 64: 2585-2594.