In situ monitoring of intracellular controlled drug release from mesoporous silica nanoparticles coated with pH-responsive charge-reversal polymer

ACS Applied Materials and Interfaces

Volumn 6, Issue 20, 2014, Pages 17446-17453

  Zhang, Peng ^a   Wu, Tong ^a   Kong, Ji Lie ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

doxorubicin hydrochloride; drug delivery; mesoporous silica nanoparticles; pH controlled release; pH responsive charge reversal polymer

Indexed keywords

CHEMOTHERAPY; DISEASES; DRUG DELIVERY; LANTHANUM COMPOUNDS; MESOPOROUS MATERIALS; NANOPARTICLES; ONCOLOGY; PLASTIC COATINGS; POLYMERS; SILICA; SILICA NANOPARTICLES; SYNTHESIS (CHEMICAL); TARGETED DRUG DELIVERY;

CHARGE REVERSAL; CITRACONIC ANHYDRIDES; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED DRUG RELEASE; DOXORUBICIN HYDROCHLORIDE; DRUG DELIVERY SYSTEM; MESOPOROUS SILICA NANOPARTICLES; PH-CONTROLLED RELEASE;

CONTROLLED DRUG DELIVERY;

AMINO-PROPYL-TRIETHOXYSILANE; BIOMATERIAL; CITRACONIC ANHYDRIDE; DELAYED RELEASE FORMULATION; DOXORUBICIN; NANOPARTICLE; POLYALLYLAMINE; POLYAMINE; POLYMER; SILANE DERIVATIVE; SILICON DIOXIDE;

CELL DEATH; CELL NUCLEUS; CHEMISTRY; CONFOCAL MICROSCOPY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; DRUG RELEASE; HELA CELL LINE; HUMAN; HYDROLYSIS; INFRARED SPECTROSCOPY; INTRACELLULAR SPACE; METABOLISM; PH; PHARMACOLOGY; POROSITY; ULTRASTRUCTURE;

CELL DEATH; CELL NUCLEUS; CITRACONIC ANHYDRIDES; COATED MATERIALS, BIOCOMPATIBLE; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG LIBERATION; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INTRACELLULAR SPACE; MICROSCOPY, CONFOCAL; NANOPARTICLES; POLYAMINES; POLYMERS; POROSITY; SILANES; SILICON DIOXIDE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84908181196     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am5059519     Document Type: Article

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