Nutrients intake is associated with DNA methylation of candidate inflammatory genes in a population of obese subjects

Nutrients

Volumn 6, Issue 10, 2014, Pages 4625-4639

  Bollati, Valentina ^a,b   Favero, Chiara ^a   Albetti, Benedetta ^a   Tarantini, Letizia ^a   Moroni, Alice ^a   Byun, Hyang Min ^c   Motta, Valeria ^a   Conti, Diana Misaela ^b   Tirelli, Amedea Silvia ^b   Vigna, Luisella ^b   Bertazzi, Pier Alberto ^a,b   Pesatori, Angela Cecilia ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

CD14; DNA methylation; Et 1; HERV w; INOS; Nutrients; TNF

Indexed keywords

BETA CAROTENE; BISULFITE; CAROTENOID; CD14 ANTIGEN; ENDOTHELIN 1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; INDUCIBLE NITRIC OXIDE SYNTHASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; CHOLESTEROL; FOLIC ACID; LOW DENSITY LIPOPROTEIN; NOS2 PROTEIN, HUMAN; PLACENTA PROTEIN; RETINOL; SYNCYTIN; VIRUS ENVELOPE PROTEIN;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; DIABETES MELLITUS; DNA METHYLATION; ENDOGENOUS RETROVIRUS; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INFLAMMATION; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; NUTRIENT UPTAKE; NUTRITIONAL ASSESSMENT; OBESITY; OXIDATIVE STRESS; PYROSEQUENCING; QUESTIONNAIRE; SMOKING; AGED; BLOOD; CALORIC INTAKE; EATING; GENETICS; METABOLISM; MIDDLE AGED; NUTRITIONAL STATUS;

HUMAN ENDOGENOUS RETROVIRUS W;

ADULT; AGED; ANTIGENS, CD14; BETA CAROTENE; BODY MASS INDEX; CAROTENOIDS; CHOLESTEROL; CHOLESTEROL, HDL; DNA METHYLATION; EATING; ENDOTHELIN-1; ENERGY INTAKE; FEMALE; FOLIC ACID; GENE PRODUCTS, ENV; HUMANS; INFLAMMATION; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; NUTRITIONAL STATUS; OBESITY; OVERWEIGHT; PREGNANCY PROTEINS; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN A;

EID: 84908177730     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu6104625     Document Type: Article

References (44)

1. Chawla, A.; Nguyen, K.D.; Goh, Y.P. Macrophage-mediated inflammation in metabolic disease. Nat. Rev. Immunol. 2011, 11, 738-749.
2. Ouchi, N.; Parker, J.L.; Lugus, J.J.; Walsh, K. Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 2011, 11, 85-97.
3. Esser, N.; Legrand-Poels, S.; Piette, J.; Scheen, A.J.; Paquot, N. Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res. Clini. Pract. 2014, 105, 141-150.
4. De Liso, F.; Bonara, P.; Vigna, L.; Novembrino, C.; de Giuseppe, R.; Bamonti, F.; Carbonelli, V.; Frugoni, C.; Tirelli, A.S.; Maiavacca, R.; et al. Oxidative stress and low-grade inflammatory status as. Cardiometabolic risk factors in italian occupational overweight/obese subjects. Eur. J. Inflamm. 2013, 11, 789-796.
5. Barnard, N.D.; Bush, A.I.; Ceccarelli, A.; Cooper, J.; de Jager, C.A.; Erickson, K.I.; Fraser, G.; Kesler, S.; Levin, S.M.; Lucey, B.; et al. Dietary and lifestyle guidelines for the prevention of alzheimer's disease. Neurobiol. Aging 2014, 35, S74-S78.
6. Michas, G.; Micha, R.; Zampelas, A. Dietary fats and cardiovascular disease: Putting together the pieces of a complicated puzzle. Atherosclerosis 2014, 234, 320-328.
7. Chowdhury, R.; Warnakula, S.; Kunutsor, S.; Crowe, F.; Ward, H.A.; Johnson, L.; Franco, O.H.; Butterworth, A.S.; Forouhi, N.G.; Thompson, S.G.; et al. Association of dietary, circulating, and supplement fatty acids with coronary risk: A systematic review and meta-analysis. Ann. Intern. Med. 2014, 160, 398-406.
8. McAtee, C.P. Fitness, nutrition and the molecular basis of chronic disease. Biotechnol. Geneti. Eng. Rev. 2013, 29, 1-23.
9. Lobo, V.; Patil, A.; Phatak, A.; Chandra, N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn. Rev. 2010, 4, 118-126.
10. Vigna, L.; Novembrino, C.; de Giuseppe, R.; de Liso, F.; Sommaruga, D.; Agnelli, G.; Belluigi, V.; Riboldi, L.; Bamonti, F. Nutritional and oxidative status in occupational obese subjects. Mediterr. J. Nutr. Metab. 2011, 4, 69-74.
11. Vassalle, C.; Vigna, L.; Bianchi, S.; Maffei, S.; Novembrino, C.; De Giuseppe, R.; de Liso, F.; Vannucci, A.; Tirelli, S.; Maiavacca, R.; et al. A biomarker of oxidative stress as a nontraditional risk factor in obese subjects. Biomark. Med. 2013, 7, 633-639.
12. Ciccone, M.M.; Cortese, F.; Gesualdo, M.; Carbonara, S.; Zito, A.; Ricci, G.; de Pascalis, F.; Scicchitano, P.; Riccioni, G. Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular care. Mediat. Inflamm. 2013, 2013, 782137.
13. Pounis, G.; Costanzo, S.; di Giuseppe, R.; de Lucia, F.; Santimone, I.; Sciarretta, A.; Barisciano, P.; Persichillo, M.; de Curtis, A.; Zito, F.; et al. Consumption of healthy foods at different content of antioxidant vitamins and phytochemicals and metabolic risk factors for cardiovascular disease in men and women of the moli-sani study. Eur. J. Clin. Nutr. 2013, 67, 207-213.
14. Cencioni, C.; Spallotta, F.; Martelli, F.; Valente, S.; Mai, A.; Zeiher, A.M.; Gaetano, C. Oxidative stress and epigenetic regulation in ageing and age-related diseases. Int. J. Mol. Sci. 2013, 14, 17643-17663.
15. Halliwell, B. The antioxidant paradox: Less paradoxical now? Br. J. Clin. Pharmacol. 2013, 75, 637-644.
16. Halliwell, B. The antioxidant paradox. Lancet 2000, 355, 1179-1180.
17. Nguyen, C.T.; Gonzales, F.A.; Jones, P.A. Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: Correlation of accessibility, methylation, mecp2 binding and acetylation. Nucleic Acids Res. 2001, 29, 4598-4606.
18. Wachsman, J.T. DNA methylation and the association between genetic and epigenetic changes: Relation to carcinogenesis. Mutat. Res. 1997, 375, 1-8.
19. Chen, J.; Xu, X. Diet, epigenetic, and cancer prevention. Adv. Genet. 2010, 71, 237-255.
20. World Health Organization (WHO). Obesity: Preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ. Tech. Rep. Ser. 2000, 894, 1-253.
21. Crapanzano, R.; Vigna, L.; Tirelli, A.S.; Sommaruga, D.; Cassinelli, L.; Bertazzi, P.A.; Riboldi, L. Vitamin d as a cardiovascular risk factor in workers. G. Ital. Med. Lav. Ergon. 2012, 34, 196-198.
22. Cassinelli, L.M.; Sommaruga, D.; Tirelli, A.S.; Rossi, P.; Vigna, L. Vitamin d as a modifiable risk factor in relation to overweight and obesity. Prog. Nutr. 2012, 14, 115-126.
23. UCSC Genome Bioinformatics. Available online: https://genome.ucsc.edu/ (accessed on 3 May 2014).
24. Festi, D.; Colecchia, A.; Pini, S.; Scaioli, E.; Maffeis, C.; Coccheri, S.; Petroni, M.L. Development and application of a simple and powerful tool for nutrition and lifestyle education for the italian general population by general practitioners and family paediatricians. Mediterr. J. Nutr. Metab. 2009, 2, 139-144.
25. Tarantini, L.; Bonzini, M.; Tripodi, A.; Angelici, L.; Nordio, F.; Cantone, L.; Apostoli, P.; Bertazzi, P.A.; Baccarelli, A.A. Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation. Occup. Environ. Med. 2013, 70, 418-425.
26. Bollati, V.; Baccarelli, A.; Hou, L.; Bonzini, M.; Fustinoni, S.; Cavallo, D.; Byun, H.M.; Jiang, J.; Marinelli, B.; Pesatori, A.C.; et al. Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res. 2007, 67, 876-880.
27. American Diabetes Asssociation. Standards of medical care in diabetes-2014. Diabetes Care 2014, 37 (Suppl. 1), S14-S80.
28. Wright, S.D.; Ramos, R.A.; Tobias, P.S.; Ulevitch, R.J.; Mathison, J.C. Cd14, a receptor for complexes of lipopolysaccharide (lps) and lps binding protein. Science 1990, 249, 1431-1433.
29. Munthe-Kaas, M.C.; Bertelsen, R.J.; Torjussen, T.M.; Hjorthaug, H.S.; Undlien, D.E.; Lyle, R.; Gervin, K.; Granum, B.; Mowinckel, P.; Carlsen, K.H.; et al. Pet keeping and tobacco exposure influence cd14 methylation in childhood. Pediatr. Allergy Immunol. 2012, 23, 747-754.
30. Zhen, J.; Lu, H.; Wang, X.Q.; Vaziri, N.D.; Zhou, X.J. Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species. Am. J. Hypertens. 2008, 21, 28-34.
31. Chan, G.C.; Fish, J.E.; Mawji, I.A.; Leung, D.D.; Rachlis, A.C.; Marsden, P.A. Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. J. Immunol. 2005, 175, 3846-3861.
32. Browatzki, M.; Pfeiffer, C.A.; Schmidt, J.; Kranzhofer, R. Endothelin-1 induces cd40 but not il-6 in human monocytes via the proinflammatory transcription factor nf-kappab. Eur. J. Med. Res. 2005, 10, 197-201.
33. Vallender, T.W.; Lahn, B.T. Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. FEBS Lett. 2006, 580, 4560-4566.
34. Christensen, T. The role of ebv in ms pathogenesis. Int. MS J. 2006, 13, 52-57.
35. Perron, H.; Bernard, C.; Bertrand, J.B.; Lang, A.B.; Popa, I.; Sanhadji, K.; Portoukalian, J. Endogenous retroviral genes, herpesviruses and gender in multiple sclerosis. J. Neurol. Sci. 2009, 286, 65-72.
36. Perron, H.; Lang, A. The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation. Clin. Rev. Allergy Immunol. 2010, 39, 51-61.
37. Campion, J.; Milagro, F.I.; Goyenechea, E.; Martinez, J.A. Tnf-alpha promoter methylation as a predictive biomarker for weight-loss response. Obesity Silver Spring 2009, 17, 1293-1297.
38. Hermsdorff, H.H.; Zulet, M.A.; Puchau, B.; Martinez, J.A. Fruit and vegetable consumption and proinflammatory gene expression from peripheral blood mononuclear cells in young adults: A translational study. Nutr. Metab. 2010, 7, 42.
39. Jimenez-Gomez, Y.; Lopez-Miranda, J.; Blanco-Colio, L.M.; Marin, C.; Perez-Martinez, P.; Ruano, J.; Paniagua, J.A.; Rodriguez, F.; Egido, J.; Perez-Jimenez, F. Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men. Atherosclerosis 2009, 204, e70-e76.
40. Kanuri, G.; Spruss, A.; Wagnerberger, S.; Bischoff, S.C.; Bergheim, I. Role of tumor necrosis factor alpha (tnfalpha) in the onset of fructose-induced nonalcoholic fatty liver disease in mice. J. Nutr. Biochem. 2011, 22, 527-534.
41. Hermsdorff, H.H.; Mansego, M.L.; Campion, J.; Milagro, F.I.; Zulet, M.A.; Martinez, J.A. Tnf-alpha promoter methylation in peripheral white blood cells: Relationship with circulating tnfalpha, truncal fat and n-6 pufa intake in young women. Cytokine 2013, 64, 265-271.
42. Subramanian, S.; Chait, A. The effect of dietary cholesterol on macrophage accumulation in adipose tissue: Implications for systemic inflammation and atherosclerosis. Curr. Opin. Lipidol. 2009, 20, 39-44.
43. Liu, K. Statistical issues related to semiquantitative food-frequency questionnaires. Am. J. Clin. Nutr. 1994, 59, 262S-265S.
44. Carroll, R.J.; Pee, D.; Freedman, L.S.; Brown, C.C. Statistical design of calibration studies. Am. J. Clin. Nutr. 1997, 65, 1187S-1189S.