메뉴 건너뛰기




Volumn 13, Issue 2, 2006, Pages 52-57

The role of EBV in MS pathogenesis

Author keywords

Co factor; Epstein Barr virus; Molecular mimicry; Multiple sclerosis; Seroepidemiology

Indexed keywords

CAPSID PROTEIN; CELL NUCLEUS ANTIGEN; EARLY ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; VIRUS ANTIBODY;

EID: 33646778802     PISSN: 13528963     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (36)

References (47)
  • 1
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler D. Multiple sclerosis. J Clin Invest 2004; 113: 788-794.
    • (2004) J Clin Invest , vol.113 , pp. 788-794
    • Hafler, D.1
  • 2
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 2004; 55: 458-468.
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 3
    • 0041589180 scopus 로고    scopus 로고
    • Neuropathology of multiple sclerosis - New concepts
    • Kornek B, Lassmann H. Neuropathology of multiple sclerosis - new concepts. Brain Res Bull 2003; 61: 321-326.
    • (2003) Brain Res Bull , vol.61 , pp. 321-326
    • Kornek, B.1    Lassmann, H.2
  • 5
    • 0031953328 scopus 로고    scopus 로고
    • Effect of age at onset and parental disease status on sibling risks for MS
    • Sadovnick AD, Yee, IML, Ebers GC, Risch NJ. Effect of age at onset and parental disease status on sibling risks for MS. Neurology 1998; 50: 719-723.
    • (1998) Neurology , vol.50 , pp. 719-723
    • Sadovnick, A.D.1    Yee, I.M.L.2    Ebers, G.C.3    Risch, N.J.4
  • 6
    • 0025767289 scopus 로고
    • HLA class-II associated genetic susceptibility in multiple sclerosis: A critical evaluation
    • Olerup O, Hillert J. HLA class-II associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 1991; 38: 1-15.
    • (1991) Tissue Antigens , vol.38 , pp. 1-15
    • Olerup, O.1    Hillert, J.2
  • 8
    • 17444436401 scopus 로고    scopus 로고
    • The genetics of multiple sclerosis: Principles, background and updated results of the United Kingdom systematic genome screen
    • Chataway J, Feakes R, Coraddu F, Gray J, Deans J, Fraser M et al. The genetics of multiple sclerosis: principles, background and updated results of the United Kingdom systematic genome screen. Brain 1998; 121: 1869-1887.
    • (1998) Brain , vol.121 , pp. 1869-1887
    • Chataway, J.1    Feakes, R.2    Coraddu, F.3    Gray, J.4    Deans, J.5    Fraser, M.6
  • 11
    • 0035141553 scopus 로고    scopus 로고
    • Multiple sclerosis in the Faroe Islands: On epitome
    • Kurtzke JF, Heltberg A. Multiple sclerosis in the Faroe Islands: on epitome. J Clin Epidemiol 2001; 54: 1-22.
    • (2001) J Clin Epidemiol , vol.54 , pp. 1-22
    • Kurtzke, J.F.1    Heltberg, A.2
  • 12
    • 18744409058 scopus 로고    scopus 로고
    • Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses
    • Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses. Rev Med Virol 2005; 15: 179-211.
    • (2005) Rev Med Virol , vol.15 , pp. 179-211
    • Christensen, T.1
  • 13
    • 0035523053 scopus 로고    scopus 로고
    • Herpesvirus and multiple sclerosis
    • Simmons A. Herpesvirus and multiple sclerosis. Herpes 2001; 8: 60-03.
    • (2001) Herpes , vol.8 , pp. 60-103
    • Simmons, A.1
  • 14
    • 17144378952 scopus 로고    scopus 로고
    • A systematic review of the epidemiology and interaction of herpes simplex virus types 1 and 2
    • Looker KJ, Garnett GP. A systematic review of the epidemiology and interaction of herpes simplex virus types 1 and 2. Sex Transm Infect 2005; 81: 103-107.
    • (2005) Sex Transm Infect , vol.81 , pp. 103-107
    • Looker, K.J.1    Garnett, G.P.2
  • 15
    • 13844310858 scopus 로고    scopus 로고
    • Sixth disease and the ubiquity of human herpesviruses
    • Prober C. Sixth disease and the ubiquity of human herpesviruses. N Engl J Med 2005; 352: 753-755.
    • (2005) N Engl J Med , vol.352 , pp. 753-755
    • Prober, C.1
  • 16
    • 0035971959 scopus 로고    scopus 로고
    • Age-specific seroprevalence to varicella-zoster virus: Study in Swiss children and analysis of European data
    • Aebi C, Fischer K, Gorgievski M, Matter L, Muhlemann K. Age-specific seroprevalence to varicella-zoster virus: study in Swiss children and analysis of European data. Vaccine 2001; 19: 3097-3103.
    • (2001) Vaccine , vol.19 , pp. 3097-3103
    • Aebi, C.1    Fischer, K.2    Gorgievski, M.3    Matter, L.4    Muhlemann, K.5
  • 17
    • 13944262199 scopus 로고    scopus 로고
    • Human herpesvirus-8: Clinical features of an emerging viral pathogen
    • Bhaduri-McIntosh S. Human herpesvirus-8: clinical features of an emerging viral pathogen. Pediatr Intect Dis J 2005; 24: 81-82.
    • (2005) Pediatr Intect Dis J , vol.24 , pp. 81-82
    • Bhaduri-McIntosh, S.1
  • 19
    • 0000974298 scopus 로고    scopus 로고
    • Cytomegalovirus
    • (Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B et al. eds). Philadelphia: Lippincott Williams & Wilkins
    • Pass RF: Cytomegalovirus. In: Fields Virology, 4th edn (Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B et al. eds). Philadelphia: Lippincott Williams & Wilkins 2001; pp2675-2706.
    • (2001) Fields Virology, 4th Edn. , pp. 2675-2706
    • Pass, R.F.1
  • 20
    • 0030626495 scopus 로고    scopus 로고
    • The implications of Epstein-Barr virus in multiple sclerosis - A review
    • Munch, M, Hvas J, Christensen T, Møller-Larsen A, Haahr S. The implications of Epstein-Barr virus in multiple sclerosis - a review. Acta Neurol Scand 1997; 95 (Suppl 169): 59-64.
    • (1997) Acta Neurol Scand , vol.95 , Issue.SUPPL. 169 , pp. 59-64
    • Munch, M.1    Hvas, J.2    Christensen, T.3    Møller-Larsen, A.4    Haahr, S.5
  • 22
    • 0029311682 scopus 로고
    • Increased risk of multiple sclerosis after late Epstein-Barr virus infection: A historical prospective study
    • Haahr S, Koch-Henriksen N, Moller-Larsen A, Eriksen LS, Andersen HM. Increased risk of multiple sclerosis after late Epstein-Barr virus infection: a historical prospective study. Mult Scler 1995; 1: 73-77.
    • (1995) Mult Scler , vol.1 , pp. 73-77
    • Haahr, S.1    Koch-Henriksen, N.2    Moller-Larsen, A.3    Eriksen, L.S.4    Andersen, H.M.5
  • 23
    • 0034077488 scopus 로고    scopus 로고
    • Clinical infections and multiple sclerosis: Contributions from analytical epidemiology
    • Casetta I, Granieri E. Clinical infections and multiple sclerosis: contributions from analytical epidemiology. J Neurovirol 2000; 6 (Suppl 2): 147-151.
    • (2000) J Neurovirol , vol.6 , Issue.SUPPL. 2 , pp. 147-151
    • Casetta, I.1    Granieri, E.2
  • 24
    • 0032423861 scopus 로고    scopus 로고
    • A single subtype of Epstein-Barr virus in members of multiple sclerosis clusters
    • Munch M, Hvas J, Christensen T, Moller-Larsen A, Haahr S. A single subtype of Epstein-Barr virus in members of multiple sclerosis clusters. Acta Neurol Scand 1998; 98: 395-399.
    • (1998) Acta Neurol Scand , vol.98 , pp. 395-399
    • Munch, M.1    Hvas, J.2    Christensen, T.3    Moller-Larsen, A.4    Haahr, S.5
  • 26
    • 0034507210 scopus 로고    scopus 로고
    • Altered prevalence and reactivity of anti-Epstein-Barr virus antibodies in patients with multiple sclerosis
    • Wagner HJ, Hennig H, Jabs WJ, Siekhaus A, Wessel K et al. Altered prevalence and reactivity of anti-Epstein-Barr virus antibodies in patients with multiple sclerosis. Viral Immunol 2000; 13: 497-502.
    • (2000) Viral Immunol , vol.13 , pp. 497-502
    • Wagner, H.J.1    Hennig, H.2    Jabs, W.J.3    Siekhaus, A.4    Wessel, K.5
  • 27
    • 0034001316 scopus 로고    scopus 로고
    • Epstein-Barr virus and multiple sclerosis
    • Ascherio A, Munch M. Epstein-Barr virus and multiple sclerosis. Epidemiology 2000; 11: 220-224.
    • (2000) Epidemiology , vol.11 , pp. 220-224
    • Ascherio, A.1    Munch, M.2
  • 28
    • 0031465706 scopus 로고    scopus 로고
    • An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus
    • James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJA, Harley JB. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 1997; 100: 3019-3026.
    • (1997) J Clin Invest , vol.100 , pp. 3019-3026
    • James, J.A.1    Kaufman, K.M.2    Farris, A.D.3    Taylor-Albert, E.4    Lehman, T.J.A.5    Harley, J.B.6
  • 29
    • 0037330508 scopus 로고    scopus 로고
    • Antibodies against a human endogenous retrovirus and the preponderance of Env splice variants in multiple sclerosis patients
    • Christensen T, Sorensen PD, Hansen HJ, Moller-Larsen A. Antibodies against a human endogenous retrovirus and the preponderance of Env splice variants in multiple sclerosis patients. Mult Scler 2003; 9:6-15.
    • (2003) Mult Scler , vol.9 , pp. 6-15
    • Christensen, T.1    Sorensen, P.D.2    Hansen, H.J.3    Moller-Larsen, A.4
  • 30
    • 0031663125 scopus 로고    scopus 로고
    • The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis
    • Reiber H, Ungefehr S, Jacobi C. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Mult Scler 1998; 4: 111-117.
    • (1998) Mult Scler , vol.4 , pp. 111-117
    • Reiber, H.1    Ungefehr, S.2    Jacobi, C.3
  • 31
    • 0026699281 scopus 로고
    • Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein
    • Bray PF, Luka J, Bray PF, Culp KW, Schlight JP. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 1992; 42: 1798-1804.
    • (1992) Neurology , vol.42 , pp. 1798-1804
    • Bray, P.F.1    Luka, J.2    Bray, P.F.3    Culp, K.W.4    Schlight, J.P.5
  • 32
    • 18244378502 scopus 로고    scopus 로고
    • Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis
    • Cepok S, Zhou D, Srivastava R, Nessler S, Stei S, Bussow K et al. Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. J Clin Invest 2005; 115: 1352-1360.
    • (2005) J Clin Invest , vol.115 , pp. 1352-1360
    • Cepok, S.1    Zhou, D.2    Srivastava, R.3    Nessler, S.4    Stei, S.5    Bussow, K.6
  • 33
    • 0033983723 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen-1 (EBNA-1) associated oligoclonal bands in patients with multiple sclerosis
    • Rand KH, Houck H, Denslow ND, Heilman KM. Epstein-Barr virus nuclear antigen-1 (EBNA-1) associated oligoclonal bands in patients with multiple sclerosis. J Neurol Sci 2000; 173: 32-39.
    • (2000) J Neurol Sci , vol.173 , pp. 32-39
    • Rand, K.H.1    Houck, H.2    Denslow, N.D.3    Heilman, K.M.4
  • 34
    • 23944526944 scopus 로고    scopus 로고
    • Intrathecal antibody (IgG) production against human herpes-virus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response
    • Derfuss T, Hohlfeld R, Meinl E. Intrathecal antibody (IgG) production against human herpes-virus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response. J Neurol 2005; 252: 968-971.
    • (2005) J Neurol , vol.252 , pp. 968-971
    • Derfuss, T.1    Hohlfeld, R.2    Meinl, E.3
  • 35
    • 0033868149 scopus 로고    scopus 로고
    • Association between clinical disease activity and Epstein-Barr virus reactivation in MS
    • Wandinger KP, Jabs W, Siekhaus A, Bubel S, Trillenberg P, Wagner H et al. Association between clinical disease activity and Epstein-Barr virus reactivation in MS. Neurology 2000; 55: 178-184.
    • (2000) Neurology , vol.55 , pp. 178-184
    • Wandinger, K.P.1    Jabs, W.2    Siekhaus, A.3    Bubel, S.4    Trillenberg, P.5    Wagner, H.6
  • 36
    • 10844286423 scopus 로고    scopus 로고
    • Plasma viral load of Epstein-Barr virus and risk of multiple sclerosis
    • Wagner HJ, Munger KL, Ascherio A. Plasma viral load of Epstein-Barr virus and risk of multiple sclerosis. Eur J Neurol 2004; 11: 833-834.
    • (2004) Eur J Neurol , vol.11 , pp. 833-834
    • Wagner, H.J.1    Munger, K.L.2    Ascherio, A.3
  • 37
    • 2342482423 scopus 로고    scopus 로고
    • Brief presence of varicella-zoster viral DNA in mononuclear cells during relapses of multiple sclerosis
    • Ordonez G, Pineda B, Garcia-Navarrete R, Sotelo J. Brief presence of varicella-zoster viral DNA in mononuclear cells during relapses of multiple sclerosis. Arch Neurol 2004; 61: 529-532.
    • (2004) Arch Neurol , vol.61 , pp. 529-532
    • Ordonez, G.1    Pineda, B.2    Garcia-Navarrete, R.3    Sotelo, J.4
  • 38
    • 0029814261 scopus 로고
    • Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction
    • Sanders VJ, Felisan S, Waddell A, Tourtellotte WW. Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. J Neurovirol 1990; 2: 249-258.
    • (1990) J Neurovirol , vol.2 , pp. 249-258
    • Sanders, V.J.1    Felisan, S.2    Waddell, A.3    Tourtellotte, W.W.4
  • 39
    • 15944363765 scopus 로고    scopus 로고
    • Co-localization of human herpes virus 6 and tissue plasminogen activator in multiple sclerosis brain tissue
    • Virtanen JO, Zabriskie JB, Siren V, Friedman JE, Lyons MJ, Vaheri A et al. Co-localization of human herpes virus 6 and tissue plasminogen activator in multiple sclerosis brain tissue. Med Sci Monit 2005; 11: BR 84-87.
    • (2005) Med Sci Monit , vol.11 , pp. 84-87
    • Virtanen, J.O.1    Zabriskie, J.B.2    Siren, V.3    Friedman, J.E.4    Lyons, M.J.5    Vaheri, A.6
  • 40
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 1995; 80: 695-705.
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 41
    • 0032702603 scopus 로고    scopus 로고
    • The distinction blurs between an autoimmune versus microbial hypothesis in multiple sclerosis
    • Hafler DA. The distinction blurs between an autoimmune versus microbial hypothesis in multiple sclerosis. J Clin Invest 1999; 104: 527-529.
    • (1999) J Clin Invest , vol.104 , pp. 527-529
    • Hafler, D.A.1
  • 42
    • 0036793245 scopus 로고    scopus 로고
    • A functional and structural basis for TCR cross-reactivity in multiple sclerosis
    • Lang HL, Jacobsen H, Ikemizu S, Andersson C, Harlos K et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol 2002; 3: 940-943.
    • (2002) Nat Immunol , vol.3 , pp. 940-943
    • Lang, H.L.1    Jacobsen, H.2    Ikemizu, S.3    Andersson, C.4    Harlos, K.5
  • 43
    • 7244254454 scopus 로고    scopus 로고
    • Cerebrospinal fluid CD4+ T cells from a multiple sclerosis patient cross-recognize Epstein-Barr virus and myelin basic protein
    • Holmoy T, Kvale EO, Vartdal F. Cerebrospinal fluid CD4+ T cells from a multiple sclerosis patient cross-recognize Epstein-Barr virus and myelin basic protein. J Neurovirol 2004; 10: 278-283.
    • (2004) J Neurovirol , vol.10 , pp. 278-283
    • Holmoy, T.1    Kvale, E.O.2    Vartdal, F.3
  • 44
    • 0347997289 scopus 로고    scopus 로고
    • Altered CD8+ T cell responses to selected Epstein-Barr virus immunodominant epitopes in patients with multiple sclerosis
    • Hollsberg P, Hansen HJ, Haahr S. Altered CD8+ T cell responses to selected Epstein-Barr virus immunodominant epitopes in patients with multiple sclerosis. Clin Exp Immunol 2003; 132: 137-143.
    • (2003) Clin Exp Immunol , vol.132 , pp. 137-143
    • Hollsberg, P.1    Hansen, H.J.2    Haahr, S.3
  • 45
    • 0029083218 scopus 로고
    • The Epstein-Barr virus in autoimmunity
    • Vaughan JH. The Epstein-Barr virus in autoimmunity. Springer Semin Immunopathol 1995; 17: 203-230.
    • (1995) Springer Semin Immunopathol , vol.17 , pp. 203-230
    • Vaughan, J.H.1
  • 46
    • 6444244547 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled MRI study of anti-herpes virus therapy in MS
    • Bech E, Lycke J, Gadeberg P, Hansen HJ, Malmestrom C et al. A randomized, double-blind, placebo-controlled MRI study of anti-herpes virus therapy in MS. Neurology 2002; 58: 31-36.
    • (2002) Neurology , vol.58 , pp. 31-36
    • Bech, E.1    Lycke, J.2    Gadeberg, P.3    Hansen, H.J.4    Malmestrom, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.