메뉴 건너뛰기




Volumn 21, Issue 12, 2008, Pages 1163-1174

In vitro investigation of pig cells for resistance to human antibody-mediated rejection

Author keywords

1,3 galactosyltransferase gene knockout; Anti pig antibodies; Complement regulatory protein; Cytotoxicity; Gal 1,3Gal; Pig; Xenotransplantation

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MEMBRANE COFACTOR PROTEIN;

EID: 55649120266     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2008.00736.x     Document Type: Article
Times cited : (97)

References (33)
  • 1
    • 0347367029 scopus 로고    scopus 로고
    • Production of alpha 1,3-galactosyltransferase-deficient pigs
    • Phelps CJ, Koike C, Vaught TD, et al. Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 2003 299 : 411.
    • (2003) Science , vol.299 , pp. 411
    • Phelps, C.J.1    Koike, C.2    Vaught, T.D.3
  • 2
    • 2442567900 scopus 로고    scopus 로고
    • Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations
    • Kolber-Simonds D, Lai L, Watt SR, et al. Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations. Proc Natl Acad Sci U S A 2004 101 : 7335.
    • (2004) Proc Natl Acad Sci U S a , vol.101 , pp. 7335
    • Kolber-Simonds, D.1    Lai, L.2    Watt, S.R.3
  • 3
    • 0024297335 scopus 로고
    • Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells
    • Galili U, Shohet SB, Kobrin E, Stults CL, Macher BA. Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells. J Biol Chem 1988 263 : 17755.
    • (1988) J Biol Chem , vol.263 , pp. 17755
    • Galili, U.1    Shohet, S.B.2    Kobrin, E.3    Stults, C.L.4    MacHer, B.A.5
  • 4
    • 0026623093 scopus 로고
    • Identification of carbohydrate structures that bind human antiporcine antibodies: Implications for discordant xenografting in humans
    • Good AH, Cooper DK, Malcolm AJ, et al. Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992 24 : 559.
    • (1992) Transplant Proc , vol.24 , pp. 559
    • Good, A.H.1    Cooper, D.K.2    Malcolm, A.J.3
  • 5
    • 0027135892 scopus 로고
    • Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: Relevance to discordant xenografting in man
    • Cooper DK, Good AH, Koren E, et al. Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transpl Immunol 1993 1 : 198.
    • (1993) Transpl Immunol , vol.1 , pp. 198
    • Cooper, D.K.1    Good, A.H.2    Koren, E.3
  • 6
    • 0029039406 scopus 로고
    • Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection
    • Collins BH, Cotterell AH, McCurry KR, et al. Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection. J Immunol 1995 154 : 5500.
    • (1995) J Immunol , vol.154 , pp. 5500
    • Collins, B.H.1    Cotterell, A.H.2    McCurry, K.R.3
  • 7
    • 13444282227 scopus 로고    scopus 로고
    • Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: Initial experience
    • Kuwaki K, Tseng YL, Dor FJ, et al. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med 2005 11 : 29.
    • (2005) Nat Med , vol.11 , pp. 29
    • Kuwaki, K.1    Tseng, Y.L.2    Dor, F.J.3
  • 8
    • 13444269248 scopus 로고    scopus 로고
    • Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue
    • Yamada K, Yazawa K, Shimizu A, et al. Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 2005 11 : 32.
    • (2005) Nat Med , vol.11 , pp. 32
    • Yamada, K.1    Yazawa, K.2    Shimizu, A.3
  • 9
    • 28644446730 scopus 로고    scopus 로고
    • Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys
    • Chen G, Qian H, Starzl T, et al. Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med 2005 11 : 1295.
    • (2005) Nat Med , vol.11 , pp. 1295
    • Chen, G.1    Qian, H.2    Starzl, T.3
  • 10
    • 33745094078 scopus 로고    scopus 로고
    • Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humans
    • Hara H, Ezzelarab M, Rood PP, et al. Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humans. Xenotransplantation 2006 13 : 357.
    • (2006) Xenotransplantation , vol.13 , pp. 357
    • Hara, H.1    Ezzelarab, M.2    Rood, P.P.3
  • 11
    • 33747603670 scopus 로고    scopus 로고
    • Antibodies directed to pig non-Gal antigens in naive and sensitized baboons
    • Ezzelarab M, Hara H, Busch J, et al. Antibodies directed to pig non-Gal antigens in naive and sensitized baboons. Xenotransplantation 2006 13 : 400.
    • (2006) Xenotransplantation , vol.13 , pp. 400
    • Ezzelarab, M.1    Hara, H.2    Busch, J.3
  • 12
    • 33645365768 scopus 로고    scopus 로고
    • Incidence and cytotoxicity of antibodies in cynomolgus monkeys directed to nonGal antigens, and their relevance for experimental models
    • Rood PP, Hara H, Busch JL, et al. Incidence and cytotoxicity of antibodies in cynomolgus monkeys directed to nonGal antigens, and their relevance for experimental models. Transpl Int 2006 19 : 158.
    • (2006) Transpl Int , vol.19 , pp. 158
    • Rood, P.P.1    Hara, H.2    Busch, J.L.3
  • 13
    • 55649092751 scopus 로고    scopus 로고
    • Innate immune mechanisms predominate in GT-KO pig organ graft failure in baboons
    • (Abstract).
    • Ezzelarab M, Garcia B, Azimzadeh A, et al. Innate immune mechanisms predominate in GT-KO pig organ graft failure in baboons. Xenotransplantation 2007 14 : 403 (Abstract).
    • (2007) Xenotransplantation , vol.14 , pp. 403
    • Ezzelarab, M.1    Garcia, B.2    Azimzadeh, A.3
  • 14
    • 0002719184 scopus 로고    scopus 로고
    • Introduction of [alpha](1,2)-fucosyltransferase and its effect on [alpha]-Gal epitopes in transgenic pig
    • Koike C, Kannagi R, Takuma Y, et al. Introduction of [alpha](1,2)- fucosyltransferase and its effect on [alpha]-Gal epitopes in transgenic pig. Xenotransplantation 1996 3 : 81.
    • (1996) Xenotransplantation , vol.3 , pp. 81
    • Koike, C.1    Kannagi, R.2    Takuma, Y.3
  • 15
    • 0029959441 scopus 로고    scopus 로고
    • Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase
    • Sharma A, Okabe J, Birch P, et al. Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase. Proc Natl Acad Sci U S A 1996 93 : 7190.
    • (1996) Proc Natl Acad Sci U S a , vol.93 , pp. 7190
    • Sharma, A.1    Okabe, J.2    Birch, P.3
  • 16
    • 0032571375 scopus 로고    scopus 로고
    • Transgenic expression of human alpha1,2-fucosyltransferase (H-transferase) prolongs mouse heart survival in an ex vivo model of xenograft rejection
    • Chen CG, Salvaris EJ, Romanella M, et al. Transgenic expression of human alpha1,2-fucosyltransferase (H-transferase) prolongs mouse heart survival in an ex vivo model of xenograft rejection. Transplantation 1998 65 : 832.
    • (1998) Transplantation , vol.65 , pp. 832
    • Chen, C.G.1    Salvaris, E.J.2    Romanella, M.3
  • 17
    • 0033208674 scopus 로고    scopus 로고
    • Expression of the human alpha1,2-fucosyltransferase in transgenic pigs modifies the cell surface carbohydrate phenotype and confers resistance to human serum-mediated cytolysis
    • Costa C, Zhao L, Burton WV, et al. Expression of the human alpha1,2-fucosyltransferase in transgenic pigs modifies the cell surface carbohydrate phenotype and confers resistance to human serum-mediated cytolysis. FASEB J 1999 13 : 1762.
    • (1999) FASEB J , vol.13 , pp. 1762
    • Costa, C.1    Zhao, L.2    Burton, W.V.3
  • 19
    • 0035156757 scopus 로고    scopus 로고
    • Human membrane cofactor protein (MCP, CD 46) protects transgenic pig hearts from hyperacute rejection in primates
    • Adams DH, Kadner A, Chen RH, Farivar RS. Human membrane cofactor protein (MCP, CD 46) protects transgenic pig hearts from hyperacute rejection in primates. Xenotransplantation 2001 8 : 36.
    • (2001) Xenotransplantation , vol.8 , pp. 36
    • Adams, D.H.1    Kadner, A.2    Chen, R.H.3    Farivar, R.S.4
  • 20
    • 0035189366 scopus 로고    scopus 로고
    • Protection of xenogeneic cells from human complement-mediated lysis by the expression of human DAF, CD59 and MCP
    • Huang J, Gou D, Zhen C, et al. Protection of xenogeneic cells from human complement-mediated lysis by the expression of human DAF, CD59 and MCP. FEMS Immunol Med Microbiol 2001 31 : 203.
    • (2001) FEMS Immunol Med Microbiol , vol.31 , pp. 203
    • Huang, J.1    Gou, D.2    Zhen, C.3
  • 21
    • 10744224843 scopus 로고    scopus 로고
    • Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons
    • Loveland BE, Milland J, Kyriakou P, et al. Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons. Xenotransplantation 2004 11 : 171.
    • (2004) Xenotransplantation , vol.11 , pp. 171
    • Loveland, B.E.1    Milland, J.2    Kyriakou, P.3
  • 22
    • 33645961873 scopus 로고    scopus 로고
    • Endothelial cell protection in xenotransplantation: Looking after a key player in rejection
    • Banz Y, Rieben R. Endothelial cell protection in xenotransplantation: looking after a key player in rejection. Xenotransplantation 2006 13 : 19.
    • (2006) Xenotransplantation , vol.13 , pp. 19
    • Banz, Y.1    Rieben, R.2
  • 23
    • 35748931149 scopus 로고    scopus 로고
    • Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: Implications for xenotransplantation in infants
    • Rood PP, Tai HC, Hara H, et al. Late onset of development of natural anti-nonGal antibodies in infant humans and baboons: implications for xenotransplantation in infants. Transpl Int 2007 20 : 1050.
    • (2007) Transpl Int , vol.20 , pp. 1050
    • Rood, P.P.1    Tai, H.C.2    Hara, H.3
  • 24
    • 0023950859 scopus 로고
    • Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon
    • Cooper DK, Human PA, Lexer G, et al. Effects of cyclosporine and antibody adsorption on pig cardiac xenograft survival in the baboon. J Heart Transplant 1988 7 : 238.
    • (1988) J Heart Transplant , vol.7 , pp. 238
    • Cooper, D.K.1    Human, P.A.2    Lexer, G.3
  • 25
    • 2442616218 scopus 로고    scopus 로고
    • From ABO-incompatible human kidney transplantation to xenotransplantation
    • Alexandre GP. From ABO-incompatible human kidney transplantation to xenotransplantation. Xenotransplantation 2004 11 : 233.
    • (2004) Xenotransplantation , vol.11 , pp. 233
    • Alexandre, G.P.1
  • 26
    • 33846590924 scopus 로고    scopus 로고
    • Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs
    • Baumann BC, Stussi G, Huggel K, Rieben R, Seebach JD. Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs. Transplantation 2007 83 : 193.
    • (2007) Transplantation , vol.83 , pp. 193
    • Baumann, B.C.1    Stussi, G.2    Huggel, K.3    Rieben, R.4    Seebach, J.D.5
  • 27
    • 33644862221 scopus 로고    scopus 로고
    • The role of anti-non-Gal antibodies in the development of acute humoral xenograft rejection of hDAF transgenic porcine kidneys in baboons receiving anti-Gal antibody neutralization therapy
    • Chen G, Sun H, Yang H, et al. The role of anti-non-Gal antibodies in the development of acute humoral xenograft rejection of hDAF transgenic porcine kidneys in baboons receiving anti-Gal antibody neutralization therapy. Transplantation 2006 81 : 273.
    • (2006) Transplantation , vol.81 , pp. 273
    • Chen, G.1    Sun, H.2    Yang, H.3
  • 28
    • 0033064619 scopus 로고    scopus 로고
    • Regulation of the complement membrane attack pathway
    • Morgan BP. Regulation of the complement membrane attack pathway. Crit Rev Immunol 1999 19 : 173.
    • (1999) Crit Rev Immunol , vol.19 , pp. 173
    • Morgan, B.P.1
  • 29
    • 0027830469 scopus 로고
    • Different membrane cofactor protein (CD46) isoforms protect transfected cells against antibody and complement mediated lysis
    • Loveland BE, Johnstone RW, Russell SM, Thorley BR, McKenzie IF. Different membrane cofactor protein (CD46) isoforms protect transfected cells against antibody and complement mediated lysis. Transpl Immunol 1993 1 : 101.
    • (1993) Transpl Immunol , vol.1 , pp. 101
    • Loveland, B.E.1    Johnstone, R.W.2    Russell, S.M.3    Thorley, B.R.4    McKenzie, I.F.5
  • 30
    • 0029879429 scopus 로고    scopus 로고
    • A functional analysis of recombinant soluble CD46 in vivo and a comparison with recombinant soluble forms of CD55 and CD35 in vitro
    • Christiansen D, Milland J, Thorley BR, McKenzie IF, Loveland BE. A functional analysis of recombinant soluble CD46 in vivo and a comparison with recombinant soluble forms of CD55 and CD35 in vitro. Eur J Immunol 1996 26 : 578.
    • (1996) Eur J Immunol , vol.26 , pp. 578
    • Christiansen, D.1    Milland, J.2    Thorley, B.R.3    McKenzie, I.F.4    Loveland, B.E.5
  • 31
    • 0034292339 scopus 로고    scopus 로고
    • Cooperation between decay-accelerating factor and membrane cofactor protein in protecting cells from autologous complement attack
    • Brodbeck WG, Mold C, Atkinson JP, Medof ME. Cooperation between decay-accelerating factor and membrane cofactor protein in protecting cells from autologous complement attack. J Immunol 2000 165 : 3999.
    • (2000) J Immunol , vol.165 , pp. 3999
    • Brodbeck, W.G.1    Mold, C.2    Atkinson, J.P.3    Medof, M.E.4
  • 32
    • 33750988213 scopus 로고    scopus 로고
    • Intravascular thrombosis in discordant xenotransplantation
    • Crikis S, Cowan PJ, d'Apice AJ. Intravascular thrombosis in discordant xenotransplantation. Transplantation 2006 82 : 1119.
    • (2006) Transplantation , vol.82 , pp. 1119
    • Crikis, S.1    Cowan, P.J.2    D'Apice, A.J.3
  • 33
    • 34447642540 scopus 로고    scopus 로고
    • Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: Where do we go from here?
    • Cooper DK, Dorling A, Pierson III. RN, et al. Alpha1,3- galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here? Transplantation 2007 84 : 1.
    • (2007) Transplantation , vol.84 , pp. 1
    • Cooper, D.K.1    Dorling, A.2    Piersoniii., R.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.