메뉴 건너뛰기




Volumn 100, Issue 4, 2014, Pages 370-376

Markers to predict the efficacy of bevacizumab in the treatment of metastatic colorectal cancer

Author keywords

Bevacizumab; Biomarker; Colorectal cancer; Efficacy; Metastasis

Indexed keywords

BEVACIZUMAB; BIOLOGICAL MARKER; CA 125 ANTIGEN; CA 19-9 ANTIGEN; CARBONATE DEHYDRATASE IX; CARCINOEMBRYONIC ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LACTATE DEHYDROGENASE; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN D; ANGIOGENESIS INHIBITOR; B RAF KINASE; BRAF PROTEIN, HUMAN; MONOCLONAL ANTIBODY; TRANSCRIPTOME; VEGFA PROTEIN, HUMAN;

EID: 84908153983     PISSN: 03008916     EISSN: 20382529     Source Type: Journal    
DOI: 10.1700/1636.17888     Document Type: Review
Times cited : (11)

References (75)
  • 1
    • 0029816983 scopus 로고    scopus 로고
    • Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
    • Borgström P, Hillan KJ, Sriramarao P, Ferrara N: Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res, 56: 4032-4039, 1996.
    • (1996) Cancer Res , vol.56 , pp. 4032-4039
    • Borgström, P.1    Hillan, K.J.2    Sriramarao, P.3    Ferrara, N.4
  • 2
    • 0028935608 scopus 로고
    • Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
    • Warren RS, Yuan H, Matli MR, Gillett NA, Ferrara N: Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest, 95: 1789-1797, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 1789-1797
    • Warren, R.S.1    Yuan, H.2    Matli, M.R.3    Gillett, N.A.4    Ferrara, N.5
  • 3
    • 84860169991 scopus 로고    scopus 로고
    • Bevacizumab-based therapies in the first-line treatment of metastatic colorectal cancer
    • Strickler JH, Hurwitz HI: Bevacizumab-based therapies in the first-line treatment of metastatic colorectal cancer. Oncologist, 17: 513-524, 2012.
    • (2012) Oncologist , vol.17 , pp. 513-524
    • Strickler, J.H.1    Hurwitz, H.I.2
  • 6
    • 84886438384 scopus 로고    scopus 로고
    • Safety of bevacizumab in treating metastatic colorectal cancer: A systematic review and meta-analysis of all randomized clinical trials
    • Dai F, Shu L, Bian Y, Wang Z, Yang Z, Chu W, Gao S: Safety of bevacizumab in treating metastatic colorectal cancer: A systematic review and meta-analysis of all randomized clinical trials. Clin Drug Investig, 33: 779-788, 2013.
    • (2013) Clin Drug Investig , vol.33 , pp. 779-788
    • Dai, F.1    Shu, L.2    Bian, Y.3    Wang, Z.4    Yang, Z.5    Chu, W.6    Gao, S.7
  • 9
    • 77951100677 scopus 로고    scopus 로고
    • Increased risk of high-grade HTN with bevacizumab in cancer patients: A meta-analysis
    • Ranpura V, Pulipati B, Chu D, Zhu X, Wu S: Increased risk of high-grade HTN with bevacizumab in cancer patients: A meta-analysis. Am J Hypertens, 23: 460-468, 2010.
    • (2010) Am J Hypertens , vol.23 , pp. 460-468
    • Ranpura, V.1    Pulipati, B.2    Chu, D.3    Zhu, X.4    Wu, S.5
  • 11
    • 84871126002 scopus 로고    scopus 로고
    • Hypertension as a predictive biomarker in bevacizumab treatment for colorectal cancer patients
    • Tahover E, Uziely B, Salah A, Temper M, Peretz T, Hubert A: Hypertension as a predictive biomarker in bevacizumab treatment for colorectal cancer patients. Med Oncol, 30: 327, 2013.
    • (2013) Med Oncol , vol.30 , pp. 327
    • Tahover, E.1    Uziely, B.2    Salah, A.3    Temper, M.4    Peretz, T.5    Hubert, A.6
  • 12
    • 79951673901 scopus 로고    scopus 로고
    • Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
    • Österlund P, Soveri LM, Isoniemi H, Poussa T, Alanko T, Bono P: Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy. Br J Cancer, 104: 599-604, 2011.
    • (2011) Br J Cancer , vol.104 , pp. 599-604
    • Österlund, P.1    Soveri, L.M.2    Isoniemi, H.3    Poussa, T.4    Alanko, T.5    Bono, P.6
  • 13
    • 82455166762 scopus 로고    scopus 로고
    • Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients
    • De Stefano A, Carlomagno C, Pepe S, Bianco R, De Placido S: Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients. Cancer Chemother Pharmacol, 68: 1207-1213, 2011.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1207-1213
    • De Stefano, A.1    Carlomagno, C.2    Pepe, S.3    Bianco, R.4    De Placido, S.5
  • 14
    • 60549118166 scopus 로고    scopus 로고
    • Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab
    • Scartozzi M, Galizia E, Chiorrini S, Giampieri R, Berardi R, Pierantoni C, Cascinu S: Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab. Ann Oncol, 20: 227-230, 2009.
    • (2009) Ann Oncol , vol.20 , pp. 227-230
    • Scartozzi, M.1    Galizia, E.2    Chiorrini, S.3    Giampieri, R.4    Berardi, R.5    Pierantoni, C.6    Cascinu, S.7
  • 15
    • 79957553899 scopus 로고    scopus 로고
    • Analysis of hypertension in advanced, recurrent colorectal cancer patients treated with firstline bevacizumab
    • Yamamura K, Ishigure K: Analysis of hypertension in advanced, recurrent colorectal cancer patients treated with firstline bevacizumab. Gan To Kagaku Ryoho, 38: 85-88, 2011.
    • (2011) Gan To Kagaku Ryoho , vol.38 , pp. 85-88
    • Yamamura, K.1    Ishigure, K.2
  • 17
    • 42049112958 scopus 로고    scopus 로고
    • Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer
    • Saif MW, Longo WL, Israel G: Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer. Clin Colorectal Cancer, 7: 144-148, 2008.
    • (2008) Clin Colorectal Cancer , vol.7 , pp. 144-148
    • Saif, M.W.1    Longo, W.L.2    Israel, G.3
  • 18
    • 33750558062 scopus 로고    scopus 로고
    • Skin rash secondary to bevacizumab in a patient with advanced colorectal cancer and relation to response
    • Gotlib V, Khaled S, Lapko I, Mar N, Saif MW: Skin rash secondary to bevacizumab in a patient with advanced colorectal cancer and relation to response. Anticancer Drugs, 17: 1227-1229, 2006.
    • (2006) Anticancer Drugs , vol.17 , pp. 1227-1229
    • Gotlib, V.1    Khaled, S.2    Lapko, I.3    Mar, N.4    Saif, M.W.5
  • 19
    • 84873023298 scopus 로고    scopus 로고
    • Lack of association of proteinuria and clinical outcome in patients treated with bevacizumab for metastatic colorectal cancer
    • Iwasa S, Nakajima TE, Nagashima K, Honma Y, Kato K, Hamaguchi T, Yamada Y, Shimada Y: Lack of association of proteinuria and clinical outcome in patients treated with bevacizumab for metastatic colorectal cancer. Anticancer Res, 33: 309-316, 2013.
    • (2013) Anticancer Res , vol.33 , pp. 309-316
    • Iwasa, S.1    Nakajima, T.E.2    Nagashima, K.3    Honma, Y.4    Kato, K.5    Hamaguchi, T.6    Yamada, Y.7    Shimada, Y.8
  • 20
    • 38849087252 scopus 로고    scopus 로고
    • Obesity and risk of colorectal cancer: A meta-analysis of 31 studies with 70, 000 events
    • Moghaddam AA, Woodward M, Huxley R: Obesity and risk of colorectal cancer: A meta-analysis of 31 studies with 70, 000 events. Cancer Epidemiol Biomarkers Prev, 16: 2533-2547, 2007.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2533-2547
    • Moghaddam, A.A.1    Woodward, M.2    Huxley, R.3
  • 21
    • 0345117960 scopus 로고    scopus 로고
    • Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects
    • Miyazawa-Hoshimoto S, Takahashi K, Bujo H, Hashimoto N, Saito Y: Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects. Diabetologia, 46: 1483-1488, 2003.
    • (2003) Diabetologia , vol.46 , pp. 1483-1488
    • Miyazawa-Hoshimoto, S.1    Takahashi, K.2    Bujo, H.3    Hashimoto, N.4    Saito, Y.5
  • 22
    • 58249092148 scopus 로고    scopus 로고
    • Insulin-insulin-like growth factor axis and colon cancer
    • Sridhar SS, Goodwin PJ: Insulin-insulin-like growth factor axis and colon cancer. J Clin Oncol, 27: 165-167, 2009.
    • (2009) J Clin Oncol , vol.27 , pp. 165-167
    • Sridhar, S.S.1    Goodwin, P.J.2
  • 23
    • 34848851922 scopus 로고    scopus 로고
    • Angiogenesis modulates adipogenesis and obesity
    • Cao Y: Angiogenesis modulates adipogenesis and obesity. J Clin Invest, 117: 2362-2368, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 2362-2368
    • Cao, Y.1
  • 25
    • 84880949229 scopus 로고    scopus 로고
    • Effect of increased body mass index (BMI) on time to tumour progression (TTP) in unresectable metastatic colorectal cancer (mCRC) patients treated with bevacizumab-based therapy
    • Aykan FN, Yildiz I, Sen F, Kilic L, Keskin S, Ciftci R, Karabulut S, Sakar B, Disci R: Effect of increased body mass index (BMI) on time to tumour progression (TTP) in unresectable metastatic colorectal cancer (mCRC) patients treated with bevacizumab-based therapy. Med Oncol, 30: 679, 2013.
    • (2013) Med Oncol , vol.30 , pp. 679
    • Aykan, F.N.1    Yildiz, I.2    Sen, F.3    Kilic, L.4    Keskin, S.5    Ciftci, R.6    Karabulut, S.7    Sakar, B.8    Disci, R.9
  • 27
    • 73349143677 scopus 로고    scopus 로고
    • Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer
    • Hong YS, Cho HJ, Kim SY, Jung KH, Park JW, Choi HS, Oh JH, Kim BC, Sohn DK, Kim DY, Chang HJ: Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer. BMC Cancer, 9: 246, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 246
    • Hong, Y.S.1    Cho, H.J.2    Kim, S.Y.3    Jung, K.H.4    Park, J.W.5    Choi, H.S.6    Oh, J.H.7    Kim, B.C.8    Sohn, D.K.9    Kim, D.Y.10    Chang, H.J.11
  • 29
    • 84859891997 scopus 로고    scopus 로고
    • Bevacizumab in metastatic colorectal cancer and carcinoembryonic antigen kinetics: Case report and review of literature
    • de Andrade DP, Lima JP, Lima AD, Sasse AD, dos Santos LV: Bevacizumab in metastatic colorectal cancer and carcinoembryonic antigen kinetics: Case report and review of literature. Anticancer Drugs, 22: 15-17, 2011.
    • (2011) Anticancer Drugs , vol.22 , pp. 15-17
    • De Andrade, D.P.1    Lima, J.P.2    Lima, A.D.3    Sasse, A.D.4    Dos Santos, L.V.5
  • 30
    • 80052407055 scopus 로고    scopus 로고
    • Predictors of the efficacy of FOLFIRI plus bevacizumab as second-line treatment in metastatic colorectal cancer patients
    • Suenaga M, Matsusaka S, Ueno M, Yamamoto N, Shinozaki E, Mizunuma N, Yamaguchi T, Hatake K: Predictors of the efficacy of FOLFIRI plus bevacizumab as second-line treatment in metastatic colorectal cancer patients. Surg Today, 41: 1067-1074, 2011.
    • (2011) Surg Today , vol.41 , pp. 1067-1074
    • Suenaga, M.1    Matsusaka, S.2    Ueno, M.3    Yamamoto, N.4    Shinozaki, E.5    Mizunuma, N.6    Yamaguchi, T.7    Hatake, K.8
  • 33
    • 83655184792 scopus 로고    scopus 로고
    • Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab
    • Budai B, Komlósi V, Adleff V, Pap E, Réti A, Nagy T, Kralovánszky J, Láng I, Hitre E: Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab. Pharmacogenet Genomics, 22: 69-72, 2012.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 69-72
    • Budai, B.1    Komlósi, V.2    Adleff, V.3    Pap, E.4    Réti, A.5    Nagy, T.6    Kralovánszky, J.7    Láng, I.8    Hitre, E.9
  • 35
    • 80052718134 scopus 로고    scopus 로고
    • Gene expression of vascular endothelial growth factor A, thymidylate synthase, and tissue inhibitor of metalloproteinase 3 in prediction of response to bevacizumab treatment in colorectal cancer patients
    • Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Ikeuchi H: Gene expression of vascular endothelial growth factor A, thymidylate synthase, and tissue inhibitor of metalloproteinase 3 in prediction of response to bevacizumab treatment in colorectal cancer patients. Dis Colon Rectum, 54: 1026-1035, 2011.
    • (2011) Dis Colon Rectum , vol.54 , pp. 1026-1035
    • Watanabe, T.1    Kobunai, T.2    Yamamoto, Y.3    Matsuda, K.4    Ishihara, S.5    Nozawa, K.6    Iinuma, H.7    Ikeuchi, H.8
  • 38
    • 78149468780 scopus 로고    scopus 로고
    • Dose-finding study and pharmacogenomic analysis of fixed-rate infusion of gemcitabine, irinotecan and bevacizumab in pretreated metastatic colorectal cancer patients
    • Abajo A, Rodriguez J, Bitarte N, Zarate R, Boni V, Ponz M, Chopitea A, Bandres E, Garcia-Foncillas J: Dose-finding study and pharmacogenomic analysis of fixed-rate infusion of gemcitabine, irinotecan and bevacizumab in pretreated metastatic colorectal cancer patients. Br J Cancer, 103: 1529-1535, 2010.
    • (2010) Br J Cancer , vol.103 , pp. 1529-1535
    • Abajo, A.1    Rodriguez, J.2    Bitarte, N.3    Zarate, R.4    Boni, V.5    Ponz, M.6    Chopitea, A.7    Bandres, E.8    Garcia-Foncillas, J.9
  • 39
    • 84864444473 scopus 로고    scopus 로고
    • The predictive value of single nucleotide polymorphisms in the VEGF system to the efficacy of first-line treatment with bevacizumab plus chemotherapy in patients with metastatic colorectal cancer: Results from the Nordic ACT trial
    • Hansen TF, Christensen RD, Andersen RF, Garm Spindler KL, Johnsson A, Jakobsen A: The predictive value of single nucleotide polymorphisms in the VEGF system to the efficacy of first-line treatment with bevacizumab plus chemotherapy in patients with metastatic colorectal cancer: Results from the Nordic ACT trial. Int J Colorectal Dis, 27: 715-720, 2012.
    • (2012) Int J Colorectal Dis , vol.27 , pp. 715-720
    • Hansen, T.F.1    Christensen, R.D.2    Andersen, R.F.3    Garm Spindler, K.L.4    Johnsson, A.5    Jakobsen, A.6
  • 41
    • 77955755832 scopus 로고    scopus 로고
    • Association of plasma VEGF-A, soluble VEGFR-1 and VEGFR-2 levels and clinical response and survival in advanced colorectal cancer patients receiving bevacizumab with modified FOLFOX6
    • Aoyagi Y, Iinuma H, Horiuchi A, Shimada R, Watanabe T: Association of plasma VEGF-A, soluble VEGFR-1 and VEGFR-2 levels and clinical response and survival in advanced colorectal cancer patients receiving bevacizumab with modified FOLFOX6. Oncol Lett, 1: 253-259, 2010.
    • (2010) Oncol Lett , vol.1 , pp. 253-259
    • Aoyagi, Y.1    Iinuma, H.2    Horiuchi, A.3    Shimada, R.4    Watanabe, T.5
  • 43
    • 84860208741 scopus 로고    scopus 로고
    • Vascular endothelial growth factors (VEGF) and VEGF receptor expression as predictive biomarkers for benefit with bevacizumab in metastatic colorectal cancer (mCRC): Analysis of the phase III MAX study
    • Weickhardt AJ, Williams D, Lee C, Simes J, Murone C, Wilson K, Cummins M, Asadi K, Price TJ, Mariadason J, Tebbutt NC: Vascular endothelial growth factors (VEGF) and VEGF receptor expression as predictive biomarkers for benefit with bevacizumab in metastatic colorectal cancer (mCRC): Analysis of the phase III MAX study. J Clin Oncol, 29: 3531, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 3531
    • Weickhardt, A.J.1    Williams, D.2    Lee, C.3    Simes, J.4    Murone, C.5    Wilson, K.6    Cummins, M.7    Asadi, K.8    Price, T.J.9    Mariadason, J.10    Tebbutt, N.C.11
  • 51
    • 61449202998 scopus 로고    scopus 로고
    • The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
    • Hurwitz HI, Yi J, Ince W, Novotny WF, Rosen O: The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. Oncologist, 14: 22-28, 2009.
    • (2009) Oncologist , vol.14 , pp. 22-28
    • Hurwitz, H.I.1    Yi, J.2    Ince, W.3    Novotny, W.F.4    Rosen, O.5
  • 53
    • 79960149283 scopus 로고    scopus 로고
    • Impact of KRAS and BRAF gene mutation status on outcomes from the phase III AGITG MAX trial of capecitabine alone or in combination with bevacizumab and mitomycin in advanced colorectal cancer
    • Price TJ, Hardingham JE, Lee CK, Weickhardt A, Townsend AR, Wrin JW, Chua A, Shivasami A, Cummins MM, Murone C, Tebbutt NC: Impact of KRAS and BRAF gene mutation status on outcomes from the phase III AGITG MAX trial of capecitabine alone or in combination with bevacizumab and mitomycin in advanced colorectal cancer. J Clin Oncol, 29: 2675-2682, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 2675-2682
    • Price, T.J.1    Hardingham, J.E.2    Lee, C.K.3    Weickhardt, A.4    Townsend, A.R.5    Wrin, J.W.6    Chua, A.7    Shivasami, A.8    Cummins, M.M.9    Murone, C.10    Tebbutt, N.C.11
  • 54
    • 84879590699 scopus 로고    scopus 로고
    • KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: A pooled analysis of 12 published trials
    • Petrelli F, Coinu A, Cabiddu M, Ghilardi M, Barni S: KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: A pooled analysis of 12 published trials. Med Oncol, 30: 650, 2013.
    • (2013) Med Oncol , vol.30 , pp. 650
    • Petrelli, F.1    Coinu, A.2    Cabiddu, M.3    Ghilardi, M.4    Barni, S.5
  • 56
    • 84877049200 scopus 로고    scopus 로고
    • Analysis of PTEN, VEGF, HER2 and P53 status in determining colorectal cancer benefit from bevacizumab therapy
    • Kara O, Duman BB, Kara B, Erdogan S, Parsak CK, Sakman G: Analysis of PTEN, VEGF, HER2 and P53 status in determining colorectal cancer benefit from bevacizumab therapy. Asian Pac J Cancer Prev, 13: 6397-6401, 2012.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 6397-6401
    • Kara, O.1    Duman, B.B.2    Kara, B.3    Erdogan, S.4    Parsak, C.K.5    Sakman, G.6
  • 57
    • 84884287113 scopus 로고    scopus 로고
    • Bevacizumabbased treatment in colorectal cancer with a NRAS Q61K mutation
    • Janku F, Wheler JJ, Hong DS, Kurzrock R: Bevacizumabbased treatment in colorectal cancer with a NRAS Q61K mutation. Target Oncol, 8: 183-188, 2013.
    • (2013) Target Oncol , vol.8 , pp. 183-188
    • Janku, F.1    Wheler, J.J.2    Hong, D.S.3    Kurzrock, R.4
  • 58
    • 0942277099 scopus 로고    scopus 로고
    • Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients
    • Beerepoot LV, Mehra N, Vermaat JS, Zonnenberg BA, Gebbink MF, Voest EE: Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients. Ann Oncol, 15: 139-145, 2004.
    • (2004) Ann Oncol , vol.15 , pp. 139-145
    • Beerepoot, L.V.1    Mehra, N.2    Vermaat, J.S.3    Zonnenberg, B.A.4    Gebbink, M.F.5    Voest, E.E.6
  • 59
    • 78649484648 scopus 로고    scopus 로고
    • Circulating endothelial cells and endothelial progenitors as predictive markers of clinical response to bevacizumab-based first-line treatment in advanced colorectal cancer patients
    • Ronzoni M, Manzoni M, Mariucci S, Loupakis F, Brugnatelli S, Bencardino K, Rovati B, Tinelli C, Falcone A, Villa E, Danova M: Circulating endothelial cells and endothelial progenitors as predictive markers of clinical response to bevacizumab-based first-line treatment in advanced colorectal cancer patients. Ann Oncol, 21: 2382-2389, 2010.
    • (2010) Ann Oncol , vol.21 , pp. 2382-2389
    • Ronzoni, M.1    Manzoni, M.2    Mariucci, S.3    Loupakis, F.4    Brugnatelli, S.5    Bencardino, K.6    Rovati, B.7    Tinelli, C.8    Falcone, A.9    Villa, E.10    Danova, M.11
  • 60
    • 78649476661 scopus 로고    scopus 로고
    • The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab
    • Simkens LH, Tol J, Terstappen LW, Teerenstra S, Punt CJ, Nagtegaal ID: The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab. Ann Oncol, 21: 2447-2448, 2010.
    • (2010) Ann Oncol , vol.21 , pp. 2447-2448
    • Simkens, L.H.1    Tol, J.2    Terstappen, L.W.3    Teerenstra, S.4    Punt, C.J.5    Nagtegaal, I.D.6
  • 62
  • 65
    • 84888876366 scopus 로고    scopus 로고
    • Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab
    • Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz HI, Nixon AB: Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab. Cancer Med, 2: 234-242, 2013.
    • (2013) Cancer Med , vol.2 , pp. 234-242
    • Liu, Y.1    Starr, M.D.2    Bulusu, A.3    Pang, H.4    Wong, N.S.5    Honeycutt, W.6    Amara, A.7    Hurwitz, H.I.8    Nixon, A.B.9
  • 69
    • 84863726328 scopus 로고    scopus 로고
    • Identification of predictive circulating biomarkers of bevacizumab-containing regimen efficacy in pre-treated metastatic colorectal cancer patients
    • Abajo A, Boni V, Lopez I, Gonzalez-Huarriz M, Bitarte N, Rodriguez J, Zarate R, Bandres E, Garcia-Foncillas J: Identification of predictive circulating biomarkers of bevacizumab-containing regimen efficacy in pre-treated metastatic colorectal cancer patients. Br J Cancer, 107: 287-290, 2012.
    • (2012) Br J Cancer , vol.107 , pp. 287-290
    • Abajo, A.1    Boni, V.2    Lopez, I.3    Gonzalez-Huarriz, M.4    Bitarte, N.5    Rodriguez, J.6    Zarate, R.7    Bandres, E.8    Garcia-Foncillas, J.9
  • 71
    • 84879793148 scopus 로고    scopus 로고
    • Correlation between response to chemotherapy with concomitant bevacizumab for hepatic metastasis of colorectal cancer and degree of enhancement using contrast-enhanced computed tomography
    • Osawa G, Yoshimatsu K, Yokomizo H, Okayama S, Sagawa M, Naritaka Y: Correlation between response to chemotherapy with concomitant bevacizumab for hepatic metastasis of colorectal cancer and degree of enhancement using contrast-enhanced computed tomography. Cancer Chemother Pharmacol, 72: 209-215, 2013.
    • (2013) Cancer Chemother Pharmacol , vol.72 , pp. 209-215
    • Osawa, G.1    Yoshimatsu, K.2    Yokomizo, H.3    Okayama, S.4    Sagawa, M.5    Naritaka, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.