-
1
-
-
37649019157
-
Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients
-
Azuma M, Shi M, Danenberg KD, Gadner H, Barrett C, Jacques CJ, Sherod A, Igbal S, El-Khoueiry A, Yand D, Zhang W (2007) Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients. Pharmacogenomics 8: 1705-1713
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1705-1713
-
-
Azuma, M.1
Shi, M.2
Danenberg, K.D.3
Gadner, H.4
Barrett, C.5
Jacques, C.J.6
Sherod, A.7
Igbal, S.8
El-Khoueiry, A.9
Yand, D.10
Zhang, W.11
-
2
-
-
0035479076
-
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
-
DOI 10.1016/S0360-3016(01)01630-3, PII S0360301601016303
-
Brizel DM, Schroeder T, Scher RL, Walenta S, Clough RW, Dewhirst MW, Mueller-Klieser W (2001) Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. Int J Radiat Oncol Biol Phys 51: 349-353 (Pubitemid 32884281)
-
(2001)
International Journal of Radiation Oncology Biology Physics
, vol.51
, Issue.2
, pp. 349-353
-
-
Brizel, D.M.1
Schroeder, T.2
Scher, R.L.3
Walenta, S.4
Clough, R.W.5
Dewhirst, M.W.6
Mueller-Klieser, W.7
-
3
-
-
72249083700
-
Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases
-
Chun YS, Vauthey JN, Boonsirikamchai P (2009) Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases. JAMA 2: 2338-2344
-
(2009)
JAMA
, vol.2
, pp. 2338-2344
-
-
Chun, Y.S.1
Vauthey, J.N.2
Boonsirikamchai, P.3
-
4
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
De Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, Boni C, Cortes-Funes H, Cervantes A, Freyer G, Papamichael D, Le Bail N, Louvet C, Hendler D, de Braud F, Wilson C, Morvan F, Bonetti A (2000) Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 18: 2938-2947 (Pubitemid 30644117)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.16
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
Homerin, M.4
Hmissi, A.5
Cassidy, J.6
Boni, C.7
Cortes-Funes, H.8
Cervantes, A.9
Freyer, G.10
Papamichael, D.11
Le Bail, N.12
Louvet, C.13
Hendler, D.14
De Braud, F.15
Wilson, C.16
Morvan, F.17
Bonetti, A.18
-
5
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone. as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, Jandik P, Iveson T, Carmichael J, Alakl M, Gruia G, Awad L, Rougier P (2000) Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomized trial. Lancet 355: 1041-1047 (Pubitemid 30162806)
-
(2000)
Lancet
, vol.355
, Issue.9209
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
6
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
7
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL (2002) Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47 (Pubitemid 37328806)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
8
-
-
79956334386
-
Randomized, placebo-controlled, phase III study of first-line oxaliplatin-based chemotherapy plus PTK787/ZK222584, an oral vascular endothelial growth factor receptor inhibitor, in patients with metastatic colorectal adenocarcinoma
-
Hecht JR, Trarbach T, Hainsworth JD, Major P, Jager E, Wolff RA, Lloyd-Salvant K, Bodoky G, Pendergrass K, BergW, Chen BL, Jalava T, Meinhardt G, Laurent D, Lebwohl D, Kerr D (2011) Randomized, placebo-controlled, phase III study of first-line oxaliplatin-based chemotherapy plus PTK787/ZK222584, an oral vascular endothelial growth factor receptor inhibitor, in patients with metastatic colorectal adenocarcinoma. J Clin Oncol 20: 1997-2003
-
(2011)
J Clin Oncol
, vol.20
, pp. 1997-2003
-
-
Hecht, J.R.1
Trarbach, T.2
Hainsworth, J.D.3
Major, P.4
Jager, E.5
Wolff, R.A.6
Lloyd-Salvant, K.7
Bodoky, G.8
Pendergrass, K.9
Bergw Chen, B.L.10
Jalava, T.11
Meinhardt, G.12
Laurent, D.13
Lebwohl, D.14
Kerr, D.15
-
9
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
DOI 10.1056/NEJMoa032691
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350: 2335-2342 (Pubitemid 38702844)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
10
-
-
24644432555
-
Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986
-
DOI 10.1200/JCO.2005.05.546
-
Koehne CH, Van Cutsem E, Wils J, Bokemeyer C, El-Serafi M, Lutz MP, Lorenz M, Reichardt P, Ruckle-Lanz H, Frickhofen N, Fuchs R, Mergenthaler HG, Langenbuch T, Vanhoefer U, Rougier P, Voigtmann R, Muller L, Genicot B, Anak O, Nordlinger B (2005) Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 23: 4856-4865 (Pubitemid 46223990)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.22
, pp. 4856-4865
-
-
Kohne, C.-H.1
Van Cutsem, E.2
Wils, J.3
Bokemeyer, C.4
El-Serafi, M.5
Lutz, M.P.6
Lorenz, M.7
Reichardt, P.8
Ruckle-Lanz, H.9
Frickhofen, N.10
Fuchs, R.11
Mergenthaler, H.-G.12
Langenbuch, T.13
Vanhoefer, U.14
Rougier, P.15
Voigtmann, R.16
Muller, L.17
Genicot, B.18
Anak, O.19
Nordlinger, B.20
more..
-
11
-
-
23944498840
-
Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer
-
DOI 10.1007/s10585-005-2343-7
-
Koukourakis MI, Giatromanolaki A, Simopoulos C, Polychronidis A, Sivridis E (2005) Lactate dehydrogenase 5 (LDH5) relates to up-regulated hypoxia inducible factor pathway and metastasis in colorectal cancer. Clin Exp Metast 22: 25-30 (Pubitemid 41185858)
-
(2005)
Clinical and Experimental Metastasis
, vol.22
, Issue.1
, pp. 25-30
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Simopoulos, C.3
Polychronidis, A.4
Sivridis, E.5
-
12
-
-
0344197042
-
Lactate dehydrogenase isoenzymes 1 and 5: Differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors
-
DOI 10.1159/000074430
-
Koukourakis MI, Giatromanolaki A, Sivridis E (2003) Lactate dehydrogenase isoenzymes 1 and 5: differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors. Tumour Biol 24: 199-202 (Pubitemid 37500569)
-
(2003)
Tumor Biology
, vol.24
, Issue.4
, pp. 199-202
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
-
13
-
-
33749027749
-
Lactate dehydrogenase 5 expression in operable colorectal cancer: Strong association with survival and activated vascular endothelial growth factor pathway - A report of the tumour angiogenesis research group
-
DOI 10.1200/JCO.2006.05.9501
-
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL (2006) Lactate dehydrogenase 5 expression in operable colorectal cancer: strong association with survival and activated vascular endothelial growth factor pathway-a report of the Tumour Angiogenesis Research Group. J Clin Oncol 24: 4301-4308 (Pubitemid 46630788)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4301-4308
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Gatter, K.C.4
Harris, A.L.5
-
14
-
-
79960433377
-
Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy
-
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Trarbach T, Folprecht G (2011) Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy. Clin Cancer Res 15: 4892-4900
-
(2011)
Clin Cancer Res
, vol.15
, pp. 4892-4900
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Gatter, K.C.4
Trarbach, T.5
Folprecht, G.6
-
16
-
-
0034909448
-
Serum lactate dehydrogenase levels at presentation predict outcome of patients with limited-stage small-cell lung cancer
-
DOI 10.1097/00000421-200108000-00013
-
Tas F, Aydiner A, Demir C, Topuz E (2001b) Lactate dehydrogenase levels at presentation predict outcome of patients with limited stage small-cell lung cancer. Am J Clin Oncol 24: 376-378 (Pubitemid 32730733)
-
(2001)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.24
, Issue.4
, pp. 376-378
-
-
Tas, F.1
Aydiner, A.2
Demir, C.3
Topuz, E.4
-
17
-
-
0035205830
-
Prognostic factors in pancreatic carcinoma: Serum LDH levels predict survival in metastatic disease
-
DOI 10.1097/00000421-200112000-00003
-
Tas F, Aykan F, Alici S, Kaytan E, Aydiner A, Topuz E (2001a) Prognostic factors in pancreatic carcinoma: serum LDH levels predict survival in metastatic disease. Am J Clin Oncol 24: 547-550 (Pubitemid 33131412)
-
(2001)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.24
, Issue.6
, pp. 547-550
-
-
Tas, F.1
Aykan, F.2
Alici, S.3
Kaytan, E.4
Aydiner, A.5
Topuz, E.6
-
18
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
DOI 10.1200/JCO.2004.05.113
-
Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D, Quinaux E, Couteau C, Buyse M, Ganem G, Landi B, Colin P, Louvet C, de Gramont A (2004) FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 22: 229-237 (Pubitemid 41095086)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.2
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
Quinaux, E.7
Couteau, C.8
Buyse, M.9
Ganem, G.10
Landi, B.11
Colin, P.12
Louvet, C.13
De Gramont, A.14
-
19
-
-
79956297102
-
Randomized, placebo-controlled, phase III study of oxaliplatin, fluorouracil and leucovorin with or without PTK787/ZK222584 in patients with previously treated metastatic colorectal adenocarcinoma
-
Tournigand C, Cervantes A, Figer A, Lledo G, Flesch M, Buyse M, Mineur L, Carola E, Etienne PL, Rivera F, Chirivella I, Perez-Staub N, Louvet C (2011) Randomized, placebo-controlled, phase III study of oxaliplatin, fluorouracil and leucovorin with or without PTK787/ZK222584 in patients with previously treated metastatic colorectal adenocarcinoma. J Clin Oncol 20: 2004-2010
-
(2011)
J Clin Oncol
, vol.20
, pp. 2004-2010
-
-
Tournigand, C.1
Cervantes, A.2
Figer, A.3
Lledo, G.4
Flesch, M.5
Buyse, M.6
Mineur, L.7
Carola, E.8
Etienne, P.L.9
Rivera, F.10
Chirivella, I.11
Perez-Staub, N.12
Louvet, C.13
-
20
-
-
79956297102
-
Randomized, placebo-controlled, phase III study of oxaliplatin, fluorouracil, and leucovorin with or without PTK787/ZK 222584 in patients with previously treated metastatic colorectal adenocarcinoma
-
Van Cutsem E, Bajetta E, Valle J, Köhne CH, Hecht JR, Moore M, Germond C, Berg W, Chen BL, Jalava T, Lebwohl D, Meinhardt G, Laurent D, Lin E (2011) Randomized, placebo-controlled, phase III study of oxaliplatin, fluorouracil, and leucovorin with or without PTK787/ZK 222584 in patients with previously treated metastatic colorectal adenocarcinoma. J Clin Oncol 29: 2004-2010
-
(2011)
J Clin Oncol
, vol.29
, pp. 2004-2010
-
-
Van Cutsem, E.1
Bajetta, E.2
Valle, J.3
Köhne, C.H.4
Hecht, J.R.5
Moore, M.6
Germond, C.7
Berg, W.8
Chen, B.L.9
Jalava, T.10
Lebwohl, D.11
Meinhardt, G.12
Laurent, D.13
Lin, E.14
-
21
-
-
77956626185
-
Serological diagnostic factors for liver metastasis in patients with colorectal cancer
-
Wu XZ, Ma F, Wang XL (2010) Serological diagnostic factors for liver metastasis in patients with colorectal cancer. World J Gastroenterol 16: 4084-4088
-
(2010)
World J Gastroenterol
, vol.16
, pp. 4084-4088
-
-
Wu, X.Z.1
Ma, F.2
Wang, X.L.3
-
22
-
-
0034881358
-
Diagnostic and prognostic value of serum and peritoneal fluid lactate dehydrogenase in epithelial ovarian cancer
-
Yuce K, Baykal C, Genc C, Al A, Ayhan A (2001) Diagnostic and prognostic value of serum and peritoneal fluid lactate dehydrogenase in epithelial ovarian cancer. Eur J Gynaecol Oncol 22: 228-232 (Pubitemid 32757877)
-
(2001)
European Journal of Gynaecological Oncology
, vol.22
, Issue.3
, pp. 228-232
-
-
Yuce, K.1
Baykal, C.2
Genc, C.3
Al, A.4
Ayhan, A.5
|