Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread

Journal of Immunology

Volumn 193, Issue 9, 2014, Pages 4429-4438

  Kersh, Anna E ^a   Edwards, Lindsay J ^b   Evavold, Brian D ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EPITOPE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; INTERLEUKIN 17; LYMPHOCYTE ANTIGEN RECEPTOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ASSAY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATING DISEASE; DISEASE COURSE; DISEASE MODEL; FEMALE; FREQUENCY ANALYSIS; LYMPHOCYTE COUNT; LYMPHOCYTIC INFILTRATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; RECEPTOR BINDING; RELAPSE; REMISSION; TH17 CELL; ANIMAL; BIOSYNTHESIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DEMYELINATING AUTOIMMUNE DISEASES, CNS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPITOPES; FEMALE; INTERLEUKIN-17; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED NOD; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS;

EID: 84908142770     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401456     Document Type: Article

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