Ameliorative potential of morin in streptozotocin-induced neuropathic pain in rats

Tropical Journal of Pharmaceutical Research

Volumn 13, Issue 9, 2014, Pages 1429-1436

  Alsharari, Shakir D ^a   Al Rejaie, Salim S ^a   Abuohashish, Hatem M ^a,b   Aleisa, Abdulaziz M ^a   Parmar, Mihir Y ^a   Ahmed, Mohammed M ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Anti inflammatory; Diabetes; Morin; Neuropathy pain; Oxidative stress

Indexed keywords

CATALASE; GLUCOSE; GLUTATHIONE; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MORIN; SOMATOMEDIN C; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; MALE; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; RANDALL-SELITTO TEST; RAT; SCIATIC NERVE; STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY; TAIL FLICK TEST;

EID: 84908116305     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v13i9.8     Document Type: Article

References (48)

1. Abdi S, Haruo A, Bloomstone J. Electroconvulsive therapy for neuropathic pain: a case report and literature review Pain Physician. 2004; 7: 261-263.
2. Galer BS, Gianas A, Jensen MP. Painful diabetic polyneuropathy: epidemiology, pain description, and quality of life Diabetes Res Clin Pract. 2000; 47: 123-128.
3. Callaghan BC, Little AA, Feldman EL, Hughes RA. Enhanced glucose control for preventing and treating diabetic neuropathy Cochrane Database Syst Rev. 2012; 6: CD007543.
4. Cameron NE, Cotter MA. Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes Diabetes Res Clin Pract. 1999; 45: 137-146.
5. Stevens MJ, Obrosova I, Cao X, Van Huysen C, Greene DA. Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy Diabetes. 2000; 49: 1006-1015.
6. Calcutt NA. Experimental models of painful diabetic neuropathy J Neurol Sci. 2004; 220: 137-139.
7. Sima AA, Zhang W, Xu G, Sugimoto K, Guberski D, Yorek MA. A comparison of diabetic polyneuropathy in type II diabetic BBZDR/Wor rats and in type I diabetic BB/Wor rats Diabetologia. 2000; 43: 786-793.
8. Ceriello A. Controlling oxidative stress as a novel molecular approach to protecting the vascular wall in diabetes Curr Opin Lipidol. 2006; 17: 510-518.
9. Cunha JM, Jolivalt CG, Ramos KM, Gregory JA, Calcutt NA, Mizisin AP. Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors Metabolism. 2008; 57: 873-881.
10. Figueroa-Romero C, Sadidi M, Feldman EL. Mechanisms of disease: the oxidative stress theory of diabetic neuropathy Rev Endocr Metab Disord. 2008; 9: 301-314.
11. Zherebitskaya E, Akude E, Smith DR, Fernyhough P. Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress Diabetes. 2009; 58: 1356-1364.
12. Nandhakumar R, Salini K, Niranjali Devaraj S. Morin augments anticarcinogenic and antiproliferative efficacy against 7,12-dimethylbenz(a)-anthracene induced experimental mammary carcinogenesis Mol Cell Biochem. 2012; 364: 79-92.
13. Prahalathan P, Kumar S, Raja B. Morin attenuates blood pressure and oxidative stress in deoxycorticosterone acetate-salt hypertensive rats: a biochemical and histopathological evaluation Metabolism. 2012; 61: 1087-1099.
14. Merwid-Lad A, Trocha M, Chlebda E, et al. Effects of morin-5'-sulfonic acid sodium salt (NaMSA) on cyclophosphamide-induced changes in oxido-redox state in rat liver and kidney Hum Exp Toxicol. 2012; 31: 812-819.
15. Fang SH, Hou YC, Chang WC, Hsiu SL, Chao PD, Chiang BL. Morin sulfates/glucuronides exert antiinflammatory activity on activated macrophages and decreased the incidence of septic shock Life Sci. 2003; 74: 743-756.
16. Aleisa AM, Al-Rejaie SS, Abuohashish HM, Ahmed MM, Parmar MY. Neohro-protective role of morin against experimentally induced diabetic nephropathy Digest Journal of Nanomaterials and Biostructures. 2013; 8: 395-401.
17. Abuohashish HM, Al-Rejaie SS, Al-Hosaini KA, Parmar MY, Ahmed MM. Alleviating effects of morin against experimentally-induced diabetic osteopenia Diabetol Metab Syndr. 2013; 5: 5.
18. Ola MS, Ahmed MM, Abuohashish HM, Al-Rejaie SS, Alhomida AS. Telmisartan ameliorates neurotrophic support and oxidative stress in the retina of streptozotocin-induced diabetic rats Neurochem Res. 2013; 38: 1572-1579.
19. M. M. Al-Enazi. Ameliorative potential of rutin on streptozotocin-induced neuropathic pain in rat AJPP. 2013; 7: 2743-2754.
20. Sugimoto K, Rashid IB, Shoji M, Suda T, Yasujima M. Early changes in insulin receptor signaling and pain sensation in streptozotocin-induced diabetic neuropathy in rats J Pain. 2008; 9: 237-245.
21. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent Anal Biochem. 1968; 25: 192-205.
22. Kono Y. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase Arch Biochem Biophys. 1978; 186: 189-195.
23. Aebi H. Catalase In: Bergmeyer, ed.^eds. Methods in enzymatic analysis, City;1974; pp 674-684.
24. Lenzen S. The mechanisms of alloxan-and streptozotocin-induced diabetes Diabetologia. 2008; 51: 216-226.
25. Kamboj SS, Vasishta RK, Sandhir R. N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy J Neurochem. 2010; 112: 77-91.
26. Kapoor R, Srivastava S, Kakkar P. Bacopa monnieri modulates antioxidant responses in brain and kidney of diabetic rats Environ Toxicol Pharmacol. 2009; 27: 62-69.
27. Nadig PD, Revankar RR, Dethe SM, Narayanswamy SB, Aliyar MA. Effect of Tinospora cordifolia on experimental diabetic neuropathy Indian J Pharmacol. 2012; 44: 580-583.
28. Zhou JY, Zhou SW. Protection of trigonelline on experimental diabetic peripheral neuropathy Evid Based Complement Alternat Med. 2012; 2012: 164219.
29. Ranjithkumar R, Prathab Balaji S, Balaji B, Ramesh RV, Ramanathan M. Standardized Aqueous Tribulus terristris (nerunjil) extract attenuates hyperalgesia in experimentally induced diabetic neuropathic pain model: role of oxidative stress and inflammatory mediators Phytother Res. 2013; 27: 1646-1657.
30. Ohsawa M, Kamei J. Possible involvement of spinal protein kinase C in thermal allodynia and hyperalgesia in diabetic mice Eur J Pharmacol. 1999; 372: 221-228.
31. Freeman RS, Burch RL, Crowder RJ, et al. NGF deprivation-induced gene expression: after ten years, where do we stand? Prog Brain Res. 2004; 146: 111-126.
32. Scarth JP. Modulation of the growth hormone-insulin-like growth factor (GH-IGF) axis by pharmaceutical, nutraceutical and environmental xenobiotics: an emerging role for xenobiotic-metabolizing enzymes and the transcription factors regulating their expression. A review Xenobiotica. 2006; 36: 119-218.
33. Bolajoko EB, Mossanda KS, Adeniyi F, Akinosun O, Fasanmade A, Moropane M. Antioxidant and oxidative stress status in type 2 diabetes and diabetic foot ulcer S Afr Med J. 2008; 98: 614-617.
34. Julius U, Drel VR, Grassler J, Obrosova IG. Nitrosylated proteins in monocytes as a new marker of oxidativenitrosative stress in diabetic subjects with macroangiopathy Exp Clin Endocrinol Diabetes. 2009; 117: 72-77.
35. Bonnefont-Rousselot D. Glucose and reactive oxygen species Curr Opin Clin Nutr Metab Care. 2002; 5: 561-568.
36. Halliwell B. Drug antioxidant effects. A basis for drug selection? Drugs. 1991; 42: 569-605.
37. Cui XP, Li BY, Gao HQ, Wei N, Wang WL, Lu M. Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats J Nutr Sci Vitaminol (Tokyo). 2008; 54: 321-328.
38. Brownlee M. The pathobiology of diabetic complications: a unifying mechanism Diabetes. 2005; 54: 1615-1625.
39. Navarro-Gonzalez JF, Mora-Fernandez C. The role of inflammatory cytokines in diabetic nephropathy J Am Soc Nephrol. 2008; 19: 433-442.
40. Mora A, Paya M, Rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation Biochem Pharmacol. 1990; 40: 793-797.
41. Wu TW, Fung KP, Yang CC, Weisel RD. Antioxidation of human low density lipoprotein by morin hydrate Life Sci. 1995; 57: PL51-56.
42. Wu TW, Zeng LH, Wu J, Fung KP. Morin hydrate is a plant-derived and antioxidant-based hepatoprotector Life Sci. 1993; 53: PL 213-218.
43. Kapoor R, Kakkar P. Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes PLoS One. 2012; 7: e41663.
44. Zhang R, Kang KA, Kang SS, Park JW, Hyun JW. Morin (2',3,4',5,7-pentahydroxyflavone) protected cells against gamma-radiation-induced oxidative stress Basic Clin Pharmacol Toxicol. 2011; 108: 63-72.
45. Galvez J, Coelho G, Crespo ME, et al. Intestinal antiinflammatory activity of morin on chronic experimental colitis in the rat Aliment Pharmacol Ther. 2001; 15: 2027-2039.
46. Kim JW, Lee JH, Hwang BY et al. Morin inhibits Fyn kinase in mast cells and IgE-mediated type I hypersensitivity response in vivo Biochem Pharmacol. 2009; 77: 1506-1512.
47. Harasstani OA, Moin S, Tham CL, et al.. Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells Inflamm Res. 2010; 59: 711-721.
48. Chen WP, Wang YL, Tang JL, Hu PF, Bao JP, Wu LD. Morin inhibits interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes Int Immunopharmacol. 2012; 12: 447-452