The important ergot alkaloid intermediate chanoclavine-I produced in the yeast saccharomyces cerevisiae by the combined action of EasC and EasE from aspergillus japonicus

Microbial Cell Factories

Volumn 13, Issue 1, 2014, Pages

  Nielsen, Curt A F ^a   Folly, Christophe ^a   Hatsch, Anaëlle ^a   Molt, Andrea ^b   Schröder, Hartwig ^b   O'Connor, Sarah E ^c   Naesby, Michael ^a  

^a EVOLVA SA   (Switzerland)

^b BASF SE   (Germany)

^c JOHN INNES CENTRE   (United Kingdom)

Author keywords

Chanoclavine I; Ergot alkaloids; Metabolic engineering; Pathway reconstruction; S. cerevisiae

Indexed keywords

CHANOCLAVINE I; EASC PROTEIN; EASE PROTEIN; ERGOT ALKALOID; ERO1 PROTEIN; FUNGAL ENZYME; PDI1 PROTEIN; UNCLASSIFIED DRUG; CHANOCLAVINE; ERGOLINE DERIVATIVE; FUNGAL PROTEIN; SIGNAL PEPTIDE; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; ARTICLE; ASPERGILLUS JAPONICUS; CONTROLLED STUDY; DISULFIDE BOND; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PEROXISOME; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; ASPERGILLUS; BIOSYNTHESIS; CHEMISTRY; FUNGAL GENE; GENETIC ENGINEERING; GENETICS; METABOLISM; OPEN READING FRAME;

ASPERGILLUS; BIOSYNTHETIC PATHWAYS; ERGOLINES; ERGOT ALKALOIDS; FUNGAL PROTEINS; GENES, FUNGAL; GENETIC ENGINEERING; OPEN READING FRAMES; PEROXISOMES; PROTEIN SORTING SIGNALS; SACCHAROMYCES CEREVISIAE; TRYPTOPHAN;

EID: 84908115795     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-014-0095-2     Document Type: Article

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