Alkaloid cluster gene ccsA of the ergot fungus Claviceps purpurea encodes chanoclavine I synthase, a flavin adenine dinucleotide-containing oxidoreductase mediating the transformation of N-methyl-dimethylallyltryptophan to chanoclavine I

Applied and Environmental Microbiology

Volumn 76, Issue 6, 2010, Pages 1822-1830

  Lorenz, Nicole ^a   Olšovská, Jana ^b   Šulc, Miroslav ^b   Tudzynski, Paul ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID BIOSYNTHESIS; AXENIC CULTURE; BIOTECHNOLOGICAL APPLICATIONS; CLAVICEPS PURPUREA; CLUSTER GENES; COMPLEMENTATION; ERGOT ALKALOIDS; FLAVIN ADENINE DINUCLEOTIDE; GENE CLUSTERS; KNOCKOUT MUTANT; OXIDOREDUCTASES; PRODUCTION STRAIN; SECONDARY METABOLITES; SYNTHASES; WILD-TYPE STRAIN;

BIOSYNTHESIS; GENES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; THIN LAYER CHROMATOGRAPHY;

BIOCHEMISTRY;

CHANOCLAVINE; DRUG DERIVATIVE; ERGOLINE DERIVATIVE; FLAVINE ADENINE NUCLEOTIDE; FUNGAL PROTEIN; OXIDOREDUCTASE; TRYPTOPHAN;

ALKALOID; BIOTECHNOLOGY; BIOTRANSFORMATION; CATALYSIS; CHROMATOGRAPHY; ENZYME ACTIVITY; FUNGUS; GENE EXPRESSION; MASS SPECTROMETRY; SECONDARY METABOLITE;

ARTICLE; BIOLOGICAL MODEL; BIOSYNTHESIS; CLAVICEPS; COENZYME; ENZYMOLOGY; GENE DELETION; GENETIC COMPLEMENTATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; THIN LAYER CHROMATOGRAPHY;

BIOSYNTHETIC PATHWAYS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CLAVICEPS; COENZYMES; ERGOLINES; FLAVIN-ADENINE DINUCLEOTIDE; FUNGAL PROTEINS; GENE DELETION; GENETIC COMPLEMENTATION TEST; MASS SPECTROMETRY; MODELS, BIOLOGICAL; OXIDOREDUCTASES; TRYPTOPHAN;

ASCOMYCOTA; CLAVICEPS PURPUREA; SCLEROTIUM (ASCOMYCOTA);

EID: 77749260568     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00737-09     Document Type: Article

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