Induction of long-term immunity against respiratory syncytial virus glycoprotein by an osmotic polymeric nanocarrier

Acta Biomaterialia

Volumn 10, Issue 11, 2014, Pages 4606-4617

  Firdous, Jannatul ^a,b   Islam, Mohammad Ariful ^a,b,c   Park, Sung Moo ^a,b   Cheon, In Su ^a,d   Shim, Byoung Shik ^d   Yoon, Hyo Shin ^a   Song, Manki ^d   Chang, Jun ^e   Choi, Yun Jaie ^a   Park, Yeong Min ^f   Boraschi, Diana ^g   Han, Seung Hyun ^h   Cho, Chong Su ^a   Yun, Cheol Heui ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c HARVARD MEDICAL SCHOOL   (United States)

^d International Vaccine Institute   (South Korea)

^e Ewha Womans University   (South Korea)

^f Konkuk University School of Medicine   (South Korea)

^g INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^h School of Dentistry   (South Korea)

Author keywords

Adjuvant activity; Enhanced phagocytosis; Long term antibody response; Osmotically active polysorbitol transporter; RSV glycoprotein

Indexed keywords

ANTIBODIES; ANTIGENS; GLYCOPROTEINS; OSMOSIS; VIRUSES;

ADJUVANT ACTIVITY; ANTIBODIES RESPONSE; ENHANCED PHAGOCYTOSE; LONG-TERM ANTIBODY RESPONSE; OSMOTICALLY ACTIVE POLYSORBITOL TRANSPORTER; PHAGOCYTIC CELLS; POLY(ETHYLENIMINE); PROPERTY; RESPIRATORY SYNCYTIAL VIRUS; RESPIRATORY SYNCYTIAL VIRUS GLYCOPROTEIN;

ANTIGEN-ANTIBODY REACTIONS;

ACRYLIC ACID DERIVATIVE; CHOLERA TOXIN; GLYCOPROTEIN; IMMUNOLOGICAL ADJUVANT; NANOCARRIER; POLYETHYLENEIMINE; POLYSACCHARIDE; POLYSORBITOL TRANSPORTER; SORBITOL DIACRYLATE; UNCLASSIFIED DRUG; FLUORESCEIN ISOTHIOCYANATE; NANOPARTICLE; POLYESTER; POLYSORBITOL-BASED OSMOTICALLY ACTIVE TRANSPORTER POLYMER; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN CELL; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; MACROPHAGE ACTIVATION; MOLECULAR STABILITY; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; OSMOSIS; PHAGOCYTOSIS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SURFACE CHARGE; VIRUS IMMUNITY; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL LINE; CELL SHAPE; CHEMISTRY; DRUG EFFECTS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNITY; IMMUNOLOGY; MACROPHAGE; OSMOLARITY; SYNTHESIS; ULTRASTRUCTURE;

RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANIMALS; CELL LINE; CELL SHAPE; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; GLYCOPROTEINS; HUMANS; IMMUNITY; MACROPHAGES; MICE, INBRED BALB C; MICE, INBRED C57BL; NANOPARTICLES; OSMOLAR CONCENTRATION; PHAGOCYTOSIS; POLYESTERS; POLYETHYLENEIMINE; RESPIRATORY SYNCYTIAL VIRUSES; VIRAL PROTEINS;

EID: 84908102828     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.07.034     Document Type: Article

References (53)

1. S. Storey Respiratory syncytial virus market Nat Rev Drug Discov 9 2010 15 16
2. N. Sigurs, R. Bjarnason, F. Sigurbergsson, and B. Kjellman Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7 Am J Resp Crit Care 161 2000 1501 1507
3. N. Sigurs, R. Bjarnason, F. Sigurbergsson, B. Kjellman, and B. Bjorksten Asthma and immunoglobulin-E antibodies after respiratory syncytial virus bronchiolitis-a prospective cohort study with matched controls Pediatrics 95 1995 500 505
4. C.B. Hall, C.E. Long, and K.C. Schnabel Respiratory syncytial virus infections in previously healthy working adults Clin Infect Dis 33 2001 792 796
5. M. Beem Repeated infections with respiratory syncytial virus J Immunol 98 1967 1115 1122
6. W.P. Glezen, L.H. Taber, A.L. Frank, and J.A. Kasel Risk of primary infection and reinfection with respiratory syncytial virus Am J Dis Child 140 1986 543 546
7. C.B. Hall, E.E. Walsh, C.E. Long, and K.C. Schnabel Immunity to and frequency of reinfection with respiratory syncytial virus J Infect Dis 163 1991 693 698
8. N. Krishnamoorthy, A. Khare, T.B. Oriss, M. Raundhal, C. Morse, and M. Yarlagadda Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma Nat Med 18 2012 1525 1530
9. R.C. Welliver Pharmacotherapy of respiratory syncytial virus infection Curr Opin Pharmacol 10 2010 289 293
10. H. Wu, D.S. Pfarr, G.A. Losonsky, and P.A. Kiener Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab Curr Top Microbiol Immunol 317 2008 103 123
11. M. Magro, D. Andreu, P. Gomez-Puertas, J.A. Melero, and C. Palomo Neutralization of human respiratory syncytial virus infectivity by antibodies and low-molecular-weight compounds targeted against the fusion glycoprotein J Virol 84 2010 7970 7982
12. W. Olszewska, and P. Openshaw Emerging drugs for respiratory syncytial virus infection Expert Opin Emerg Drugs 14 2009 207 217
13. O. Adams, L. Bonzel, A. Kovacevic, E. Mayatepek, T. Hoehn, and M. Vogel Palivizumab-resistant human respiratory syncytial virus infection in infancy Clin Infect Dis 51 2010 185 188
14. F. Tayyari, D. Marchant, T.J. Moraes, W. Duan, P. Mastrangelo, and R.G. Hegele Identification of nucleolin as a cellular receptor for human respiratory syncytial virus Nat Med 17 2011 1132 1135
15. J. DeVincenzo, R. Lambkin-Williams, T. Wilkinson, J. Cehelsky, S. Nochur, and E. Walsh A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus Proc Natl Acad Sci USA 107 2010 8800 8805
16. W. Olszewska, G. Ispas, C. Schnoeller, D. Sawant, T. Van de Casteele, and D. Nauwelaers Antiviral and lung protective activity of a novel respiratory syncytial virus fusion inhibitor in a mouse model Eur Respir J 38 2011 401 408
17. R.A. Tripp, L.P. Jones, L.M. Haynes, H. Zheng, P.M. Murphy, and L.J. Anderson CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein Nat Immunol 2 2001 732 738
18. J.B. Ulmer, U. Valley, and R. Rappuoli Vaccine manufacturing: challenges and solutions Nat Biotechnol 24 2006 1377 1383
19. K. Hu, J. Dou, F. Yu, X. He, X. Yuan, and Y. Wang An ocular mucosal administration of nanoparticles containing DNA vaccine pRSC-gD-IL-21 confers protection against mucosal challenge with herpes simplex virus type 1 in mice Vaccine 29 2011 1455 1462
20. F. Wegmann, K.H. Gartlan, A.M. Harandi, S.A. Brinckmann, M. Coccia, and W.R. Hillson Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens Nat Biotechnol 30 2012 883 888
21. G. Orr, D.J. Panther, K.J. Cassens, J.L. Phillips, B.J. Tarasevich, and J.G. Pounds Syndecan-1 mediates the coupling of positively charged submicrometer amorphous silica particles with actin filaments across the alveolar epithelial cell membrane Toxicol Appl Pharmacol 236 2009 210 220
22. M. Cendoroglo, S. Sundaram, B.L. Jaber, and B.J.G. Pereira Effect of glucose concentration, osmolality, and sterilization process of peritoneal dialysis fluids on cytokine production by peripheral blood mononuclear cells and polymorphonuclear cell functions in vitro Am J Kidney Dis 31 1998 273 282
23. N.M. Otto, R. Schindler, A. Lun, O. Boenisch, U. Frei, and M. Oppert Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro Crit Care 12 2008 R107
24. M.H. Wu, G. Dirnopoulos, A. Mantalaris, and J. Varley The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line Biotechnol Appl Biochem 40 2004 41 46
25. M.A. Islam, C.H. Yun, Y.J. Choi, J.Y. Shin, R. Arote, and H.L. Jiang Accelerated gene transfer through a polysorbitol-based transporter mechanism Biomaterials 32 2011 9908 9924
26. Q.P. Luu, J.Y. Shin, Y.K. Kim, M.A. Islam, S.K. Kang, and M.H. Cho High gene transfer by the osmotic polysorbitol-mediated transporter through the selective caveolae endocytic pathway Mol Pharm 9 2012 2206 2218
27. M.A. Islam, J.Y. Shin, J. Firdous, T.E. Park, Y.J. Choi, and M.H. Cho The role of osmotic polysorbitol-based transporter in RNAi silencing via caveolae-mediated endocytosis and COX-2 expression Biomaterials 33 2012 8868 8880
28. G. Blanchard Rohner, M.D. Snape, D.F. Kelly, T. John, A. Morant, and L.M. Yu The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response J Immunol 180 2008 2165 2173
29. J.E. Jang, J.B. Lee, K.H. Kim, S.M. Park, B.S. Shim, and I.S. Cheon Evaluation of protective efficacy of respiratory syncytial virus vaccine against A and B subgroup human isolates in Korea PLoS ONE 6 2011 e23797
30. I.F. Jiang, V.B. Kumar, D.N. Lee, and C.F. Weng Acute osmotic stress affects Tilapia (Oreochromis mossambicus) innate immune responses Fish Shellfish Immunol 25 2008 841 846
31. V.B. Kumar, I.F. Jiang, H.H. Yang, and C.F. Weng Effects of serum on phagocytic activity and proteomic analysis of tilapia (Oreochromis mossambicus) serum after acute osmotic stress Fish Shellfish Immunol 26 2009 760 767
32. M.S. Lee, and G.M. Lee Effect of hypoosmotic pressure on cell growth and antibody production in recombinant Chinese hamster ovary cell culture Cytotechnology 36 2001 61 69
33. S.K. Lai, D.E. O'Hanlon, S. Harrold, S.T. Man, Y.Y. Wang, and R. Cone Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus Proc Natl Acad Sci USA 104 2007 1482 1487
34. S.S. Olmsted, J.L. Padgett, A.I. Yudin, K.J. Whaley, T.R. Moench, and R.A. Cone Diffusion of macromolecules and virus-like particles in human cervical mucus Biophys J 81 2001 1930 1937
35. C.B. He, Y.P. Hu, L.C. Yin, C. Tang, and C.H. Yin Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles Biomaterials 31 2010 3657 3666
36. L. Lyon Andrew, and J. Serpe Michael Hydrogel micro and nanoparticles 2012 Wiley-VCH, Verlag & Co. KGaA Weinleim, Germany 215
37. M. Roser, D. Fischer, and T. Kissel Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats Eur J Pharm Biopharm 46 1998 255 263
38. S. Bhattacharjee, L.H.J. de Haan, N.M. Evers, X. Jiang, A.T.M. Marcelis, and H. Zuilhof Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells Part Fibre Toxicol 7 2010 25
39. B. Sarmento, D.C. Ferreira, L. Jorgensen, and M. van de Weert Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles Eur J Pharm Biopharm 65 2007 10 17
40. K. Fujihashi, T. Koga, F.W. van Ginkel, Y. Hagiwara, and J.R. McGhee A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants Vaccine 20 2002 2431 2438
41. S.M. Moghimi, P. Symonds, J.C. Murray, A.C. Hunter, G. Debska, and A. Szewczyk A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy Mol Ther 11 2005 990 995
42. J.R. Panuska, R. Merolla, N.A. Rebert, S.P. Hoffmann, P. Tsivitse, and N.M. Cirino Respiratory syncytial virus induces interleukin-10 by human alveolar macrophages-suppression of early cytokine production and implications for incomplete immunity J Clin Invest 96 1995 2445 2453
43. J. Elias, J. Findlow, R. Borrow, A. Tremmel, M. Frosch, and U. Vogel Persistence of antibodies in laboratory staff immunized with quadrivalent meningococcal polysaccharide vaccine J Occup Med Toxicol 8 2013 4
44. T.V. Obukhanych, and M.C. Nussenzweig T-independent type II immune responses generate memory B cells J Exp Med 203 2006 305 310
45. J.B. Foote, T.I. Mahmoud, A.M. Vale, and J.F. Kearney Long-term maintenance of polysaccharide-specific antibodies by IgM-secreting cells J Immunol 188 2012 57 67
46. S.B. Han, S.K. Park, H.J. Ahn, Y.D. Yoon, Y.H. Kim, and J.J. Lee Characterization of B cell membrane receptors of polysaccharide isolated from the root of Acanthopanax koreanum Int Immunopharmacol 3 2003 683 691
47. C.P. Verschoor, A. Puchta, and D.M. Bowdish The macrophage Methods Mol Biol 844 2012 139 156
48. B.J. Bowen, and E.H. Morgan Effect of osmolar and ionic composition of the extracellular fluid on transferrin endocytosis and exocytosis and iron uptake by reticulocytes J Cell Physiol 134 1988 1 12
49. T. Akagi, M. Baba, and A. Mitsuru Biodegradable nanoparticles as vaccine adjuvants and delivery systems: regulation of immune responses by nanoparticle-based vaccine Adv Polym Sci 247 2012 31 64
50. A.K. Abbas, and A.H. Lichtman Cellular and molecular immunology 2005 Elsevier Inc. Philadelphia, PA 66 80
51. S. Foster, C.L. Duvall, E.F. Crownover, A.S. Hoffman, and P.S. Stayton Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy Bioconjug Chem 21 2010 2205 2212
52. R. Medzhitov, and C.A. Janeway Innate immunity: impact on the adaptive immune response Curr Opin Immunol 9 1997 4 9
53. S.K. Mazmanian, and D.L. Kasper The love-hate relationship between bacterial polysaccharides and the host immune system Nat Rev Immunol 6 2006 849 858