Enhanced bone tissue regeneration by antibacterial and osteoinductive silica-HACC-zein composite scaffolds loaded with rhBMP-2

Biomaterials

Volumn 35, Issue 38, 2014, Pages 10033-10045

  Zhou, Panyu ^a   Xia, Yan ^a   Cheng, Xiaosong ^a   Wang, Panfeng ^a   Xie, Yang ^a   Xu, Shuogui ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antibacterial; Bone tissue engineering; Osteoinductive; RhBMP 2; Silica HACC zein

Indexed keywords

BIOCOMPATIBILITY; CHLORINE COMPOUNDS; COMPUTERIZED TOMOGRAPHY; DEFECTS; ESCHERICHIA COLI; MEDICAL APPLICATIONS; MINERALOGY; REPAIR; SILICA; SYNTHESIS (CHEMICAL); TISSUE;

ANTIBACTERIAL; BIOMEDICAL APPLICATIONS; BONE TISSUE ENGINEERING; BONE TISSUE REGENERATION; CONFOCAL LASER SCANNING MICROSCOPY; OSTEOGENIC DIFFERENTIATION; OSTEOINDUCTIVE; RHBMP-2;

SCAFFOLDS (BIOLOGY);

CHITOSAN DERIVATIVE; HYDROXYPROPYLTRIMETHYL AMMONIUM CHLORIDE CHITOSAN; MOLECULAR SCAFFOLD; NANOPARTICLE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SILICON DIOXIDE; UNCLASSIFIED DRUG; ZEIN; AMMONIUM CHLORIDE; ANTIINFECTIVE AGENT; BMP2 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; BONE PROSTHESIS; CHITOSAN; DRUG IMPLANT; NANOCOMPOSITE; RECOMBINANT PROTEIN; SBA-15;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIUM ADHERENCE; BIOCOMPATIBILITY; BIODEGRADABLE IMPLANT; BONE CONDUCTION; BONE DEFECT; BONE DEVELOPMENT; BONE REMODELING; BONE TISSUE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ESCHERICHIA COLI; EXTRACELLULAR MATRIX; HISTOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; MICRO-COMPUTED TOMOGRAPHY; MINERALIZATION; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; RABBIT; RADIUS; STAPHYLOCOCCUS AUREUS; TISSUE ENGINEERING; TISSUE REGENERATION; ADMINISTRATION AND DOSAGE; ANIMAL; BACTERIAL PHENOMENA AND FUNCTIONS; BONE PROSTHESIS; BONE REGENERATION; CELL SURVIVAL; CHEMISTRY; DEVICE FAILURE ANALYSIS; DRUG EFFECTS; DRUG IMPLANT; PATHOLOGY; PHYSIOLOGY; PROSTHESIS; RADIUS FRACTURES; TISSUE SCAFFOLD; TREATMENT OUTCOME;

AMMONIUM CHLORIDE; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PHYSIOLOGICAL PHENOMENA; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; BONE SUBSTITUTES; CELL SURVIVAL; CHITOSAN; DRUG IMPLANTS; EQUIPMENT FAILURE ANALYSIS; HUMANS; MICE; NANOCOMPOSITES; OSTEOGENESIS; PROSTHESIS DESIGN; RABBITS; RADIUS FRACTURES; RECOMBINANT PROTEINS; SILICON DIOXIDE; TISSUE SCAFFOLDS; TREATMENT OUTCOME; ZEIN;

EID: 84908102316     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.09.009     Document Type: Article

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