Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant

Circulation

Volumn 96, Issue 10, 1997, Pages 3534-3541

  Nieuwland, Rienk ^a   Berckmans, René J ^a   Rotteveel Eijkman, Reni C ^b   Maquelin, Kyra N ^b   Roozendaal, Klaas J ^b   Jansen, Piet G M ^c   Ten Have, Klaas ^b   Eijsman, León ^b   Hack, C Erik ^d   Sturk, Augueste ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d NONE

Author keywords

Cardiopulmonary bypass; Microparticles; Thrombin

Indexed keywords

BATROXOBIN; HEPARIN LYASE; PROCOAGULANT; THROMBIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; ERYTHROCYTE; HEART SURGERY; HUMAN; HUMAN CELL; MICROPARTICLE ENZYME IMMUNOASSAY; MONOCYTE; PLASMAPHERESIS; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION;

EID: 18244426161     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.10.3534     Document Type: Article

References (31)

1. Tans G, Rosing J, Christella M, Thomassen LGD, Reeb MJ, Zwaal RFA Griffin JH. Comparison of anticoagulant and procoagulant activities of stimulated platelets and platelet-derived microparticles Blood. 1991;77:2641-2648.
2. Sims PJ, Faioni EM, Wiedmer T, Shattil SJ. Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity. J Biol Chem. 1988;263. 18205-18212.
3. Rosing J, van Rijn JLML, Bevers EM, van Dieijen G, Comfurius P, Zwaal RFA. The role of activated human platelets in prothrombin and factor X activation. Blood. 1985;65:319-332.
4. Hoffman M, Monroe DM, Roberts HR. Coagulation factor IXa binding to activated platelets and platelet-derived microparticles: a flow cytometric study. Thromb Haemost. 1992;68:74-78.
5. Gilbert GE, Sims PJ, Wiedmer T, Furie B, Furie BC, Shattil SJ. Platelet-derived microparticles express high affinity receptors for factor VIII. J Biol Chem. 1991;266:17261-17268.
6. Holme PA, Brosstad. F, Solum NO. Platelet-derived microvesicles and activated platelets express factor Xa activity. Blood Coag Fibrinol. 1995;6:302-310.
7. Sims PJ, Wiedmer T, Esmon CT, Weiss HJ, Shattil SJ. Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane: studies in Scott syndrome: an isolated defect in platelet procoagulant activity. J Biol Chem. 1989;264: 17049-17057.
8. Satta N, Toti F, Feugeas O, Bohbot A, Dachary-Prigent J, Eschwege V, Hedman H, Freyssinet JM. Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharides. J Immunol. 1994;153:3245-3255.
9. Read MA, Cordle SR, Veach RA, Carlisle CD, Hawiger J. Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells. Proc Natl Acad Sci U S A.. 1993;90:9887-9891.
10. Abrams CS, Ellison N, Budzynski AZ, Shattil SJ. Direct detection of activated platelets and platelet-derived microparticles in humans. Blood. 1990;75:128-138.
11. Wun T, Paglieroni T, Holland P. Prolonged circulation of activated platelets following plasmapheresis. J Clin Apheresis. 1994;91:10-16.
12. Katopodis JN, Kolodny L, Jy W, Horstman LL, Mao W, De Marchena EJ, Myerberg R, Ahn YS. Platelet microparticles in acute coronary ischemias. Blood. 1994;84. Abstract.
13. Monura S, Komiyama Y, Miyake T, Miyazaki Y, Kido H, Suzuki M, Kagawa H, Yanabu M, Takahashi H, Fukuhara S. Amyloid-B protein precursor-rich platelet microparticles in thrombotic diseases. Thromb Haemost. 1994;72:519-522.
14. Warkentin ET, Hayward CPM, Boshkov LK, Santos AV, Sheppard JAI, Bode AP, Kelton JG. Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood. 1994;84: 3691-3699.
15. Lee YJ, Horstman LL, Janania J, Reyes Y, Kelley RE, Ahn YS. Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias. Thromb Res. 1996;72: 295-304.
16. Nomura S, Shouzu A, Nishikawa M, Kokawa T, Yasunaga K. Significance of platelet-derived microparticles in uremia. Nephron. 1993;63:485.
17. Jy W, Horsman LL, Arce M, Ahn YS. Platelet microparticles in ITP. J Lab Clin Med. 1992;119:334-335.
18. Holme PA, Solum NO, Brosstad F. Clinical significance of platelet-derived microvesicles: demonstration of their presence in patients suffering from disseminated intravascular coagulation (DIC). Thromb Haemost. 1993;69. Abstract.
19. Woodman RC, Harker LA. Bleeding complications associated with cardiopulmonary bypass. Blood. 1990;76:1680-1697.
20. Tabuchi N, de Haan J, Boonstra PW, van Oeveren W. Activation of fibrinolysis in the pericardial cavity during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1993;106:828-833.
21. Chung JH, Gikakis N, Rao K, Drak TA, Colman RW, Edmunds H Jr. Pericardial blood activates the extrinsic coagulation pathway during clinical cardiopulmonary bypass. Circulation. 1996;93: 2014-2018.
22. Hnatowich J, Verzin F, Ruscowski M. Investigations of avidin and biotin for imaging applications. J Nucl Med. 1987;28:1294-1302.
23. Dors DM, Nuijens JH, Huijbregts CCM, Hack CE. A novel sensitive assay for functional factor XII based on the generation of kallikrein-C1-inhibitor complexes in factor XII-deficient plasma by glass-bound factor XII. Thromb Haemost. 1992;67:664-648.
24. Kessels H, Beguin S, Andree H, Hemker HC. Measurement of thrombin generation in whole blood: the effect of heparin and aspirin. Thromb Haemost. 1994;72:78-83.
25. Siljander P, Carpen O, Lassila R. Platelet-derived microparticles associate with fibrin during thrombosis. Blood. 1996;87:4651-4663.
26. Rotteveel RC, Roozendaal KJ, Weijers RNM, Eijsman L. Influence of heparin, protamine and polybrene on the time integral of thrombin generation (endogenous thrombin potential). Haemostasis. 1996;26:1-10.
27. Molino M, Di Lallo M, Martelli N, de Gaetano G, Cerletti C. Effects of leukocyte-derived cathepsin G on platelet membrane glycoprotein Ib-IX and IIb-IIIa complexes: a comparison with thrombin. Blood. 1993;82:2442-2451.
28. Adelman B, Michelson AD, Greenberg J, Handin RI. Proteolysis of platelet glycoprotein Ib by plasmin is facilitated by plasmin lysine-binding regions. Blood. 1986;68:1280-1284.
29. Gemmell CH, Ramirez SM, Yeo EL, Sefton MV. Platelet activation in whole blood by artificial surfaces: identification of platelet-derived microparticles and activated platelet binding to leukocytes as material-induced activation events. J Lab Clin Med. 1995;125:276-287.
30. Hemker HC, Beguin S. Thrombin generation in plasma: its assessment via the endogenous thrombin potential. Thromb Haemost. 1995;74:134-138.
31. Stuart MCA, Bevers EM, Comfurius P, Zwaal RFA, Reutelingsperger CPM, Frederik PM. Ultrastructural detection of surface exposed phosphatidylserine on activated blood platelets. Thromb Haemost. 1994;71:1145-1151.