메뉴 건너뛰기




Volumn 18, Issue 2, 2011, Pages 105-112

Direct Effects of Phosphate on Vascular Cell Function

Author keywords

Chronic kidney disease; Elastin degradation; Phosphate; Smooth muscle cell; Vascular calcification

Indexed keywords

PHOSPHATE;

EID: 79952613184     PISSN: 15485595     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ackd.2010.12.002     Document Type: Review
Times cited : (105)

References (88)
  • 2
    • 64949130692 scopus 로고    scopus 로고
    • The emerging role of phosphate in vascular calcification
    • Giachelli C. The emerging role of phosphate in vascular calcification. Kidney Int 2009, 75:890-897.
    • (2009) Kidney Int , vol.75 , pp. 890-897
    • Giachelli, C.1
  • 3
    • 1542347890 scopus 로고    scopus 로고
    • Vascular calcification in chronic kidney disease
    • Goodman W., London G., Amann K., et al. Vascular calcification in chronic kidney disease. Am J Kidney Dis 2004, 43:572-579.
    • (2004) Am J Kidney Dis , vol.43 , pp. 572-579
    • Goodman, W.1    London, G.2    Amann, K.3
  • 4
    • 0042885985 scopus 로고    scopus 로고
    • Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality
    • London G., Guérin A., Marchais S., Métivier F., Pannier B., Adda H. Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 2003, 18:1731-1740.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1731-1740
    • London, G.1    Guérin, A.2    Marchais, S.3    Métivier, F.4    Pannier, B.5    Adda, H.6
  • 5
    • 0035916234 scopus 로고    scopus 로고
    • Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure
    • Guerin A., Blacher J., Pannier B., Marchais S., Safar M., London G. Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. Circulation 2001, 103:987-992.
    • (2001) Circulation , vol.103 , pp. 987-992
    • Guerin, A.1    Blacher, J.2    Pannier, B.3    Marchais, S.4    Safar, M.5    London, G.6
  • 7
    • 0034995079 scopus 로고    scopus 로고
    • Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells
    • Ahmed S., O'Neill K., Hood A., Evan A., Moe S. Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells. Am J Kidney Dis 2001, 37:1267-1276.
    • (2001) Am J Kidney Dis , vol.37 , pp. 1267-1276
    • Ahmed, S.1    O'Neill, K.2    Hood, A.3    Evan, A.4    Moe, S.5
  • 8
    • 33745962708 scopus 로고    scopus 로고
    • Molecular mechanisms of vascular calcification: lessons learned from the aorta
    • Shao J., Cai J., Towler D. Molecular mechanisms of vascular calcification: lessons learned from the aorta. Arterioscler Thromb Vasc Biol 2006, 26:1423-1430.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1423-1430
    • Shao, J.1    Cai, J.2    Towler, D.3
  • 9
    • 0033565955 scopus 로고    scopus 로고
    • Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly
    • Otto C., Lind B., Kitzman D., Gersh B., Siscovick D. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 1999, 341:142-147.
    • (1999) N Engl J Med , vol.341 , pp. 142-147
    • Otto, C.1    Lind, B.2    Kitzman, D.3    Gersh, B.4    Siscovick, D.5
  • 10
    • 0037388830 scopus 로고    scopus 로고
    • Valvular and perivalvular abnormalities in end-stage renal disease
    • Umana E., Ahmed W., Alpert M. Valvular and perivalvular abnormalities in end-stage renal disease. Am J Med Sci 2003, 325:237-242.
    • (2003) Am J Med Sci , vol.325 , pp. 237-242
    • Umana, E.1    Ahmed, W.2    Alpert, M.3
  • 11
    • 0031920748 scopus 로고    scopus 로고
    • Association of serum phosphorus and calcium × phosphate product with mortality risk in chronic hemodialysis patients: a national study
    • Block G., Hulbert-Shearon T., Levin N., Port F. Association of serum phosphorus and calcium × phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis 1998, 31:607-617.
    • (1998) Am J Kidney Dis , vol.31 , pp. 607-617
    • Block, G.1    Hulbert-Shearon, T.2    Levin, N.3    Port, F.4
  • 12
    • 18144402703 scopus 로고    scopus 로고
    • Predictors and consequences of altered mineral metabolism: the Dialysis Outcomes and Practice Patterns Study
    • Young E., Albert J., Satayathum S., et al. Predictors and consequences of altered mineral metabolism: the Dialysis Outcomes and Practice Patterns Study. Kidney Int 2005, 67:1179-1187.
    • (2005) Kidney Int , vol.67 , pp. 1179-1187
    • Young, E.1    Albert, J.2    Satayathum, S.3
  • 13
    • 34248522825 scopus 로고    scopus 로고
    • Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community
    • Dhingra R., Sullivan L., Fox C., et al. Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med 2007, 167:879-885.
    • (2007) Arch Intern Med , vol.167 , pp. 879-885
    • Dhingra, R.1    Sullivan, L.2    Fox, C.3
  • 14
    • 33750123431 scopus 로고    scopus 로고
    • Mineral metabolism and cardiovascular morbidity and mortality risk: peritoneal dialysis patients compared with haemodialysis patients
    • Noordzij M., Korevaar J., Bos W., et al. Mineral metabolism and cardiovascular morbidity and mortality risk: peritoneal dialysis patients compared with haemodialysis patients. Nephrol Dial Transplant 2006, 21:2513-2520.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 2513-2520
    • Noordzij, M.1    Korevaar, J.2    Bos, W.3
  • 15
    • 49749113618 scopus 로고    scopus 로고
    • Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    • Tentori F., Blayney M., Albert J., et al. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 2008, 52:519-530.
    • (2008) Am J Kidney Dis , vol.52 , pp. 519-530
    • Tentori, F.1    Blayney, M.2    Albert, J.3
  • 17
    • 0036310682 scopus 로고    scopus 로고
    • Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients
    • Chertow G., Burke S., Raggi P. Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int 2002, 62:245-252.
    • (2002) Kidney Int , vol.62 , pp. 245-252
    • Chertow, G.1    Burke, S.2    Raggi, P.3
  • 18
    • 33847223412 scopus 로고    scopus 로고
    • Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients
    • Block G., Raggi P., Bellasi A., Kooienga L., Spiegel D. Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int 2007, 71:438-441.
    • (2007) Kidney Int , vol.71 , pp. 438-441
    • Block, G.1    Raggi, P.2    Bellasi, A.3    Kooienga, L.4    Spiegel, D.5
  • 19
    • 35848951189 scopus 로고    scopus 로고
    • The progression of coronary artery calcification in predialysis patients on calcium carbonate or sevelamer
    • Russo D., Miranda I., Ruocco C., et al. The progression of coronary artery calcification in predialysis patients on calcium carbonate or sevelamer. Kidney Int 2007, 72:1255-1261.
    • (2007) Kidney Int , vol.72 , pp. 1255-1261
    • Russo, D.1    Miranda, I.2    Ruocco, C.3
  • 20
    • 43849094954 scopus 로고    scopus 로고
    • A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study
    • Qunibi W., Moustafa M., Muenz L., et al. A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study. Am J Kidney Dis 2008, 51:952-965.
    • (2008) Am J Kidney Dis , vol.51 , pp. 952-965
    • Qunibi, W.1    Moustafa, M.2    Muenz, L.3
  • 21
    • 20544433192 scopus 로고    scopus 로고
    • Serum phosphate levels and mortality risk among people with chronic kidney disease
    • Kestenbaum B., Sampson J., Rudser K., et al. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 2005, 16:520-528.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 520-528
    • Kestenbaum, B.1    Sampson, J.2    Rudser, K.3
  • 22
    • 27444436252 scopus 로고    scopus 로고
    • Relation between serum phosphate level and cardiovascular event rate in people with coronary disease
    • Tonelli M., Sacks F., Pfeffer M., Gao Z., Curhan G. Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. Circulation 2005, 112:2627-2633.
    • (2005) Circulation , vol.112 , pp. 2627-2633
    • Tonelli, M.1    Sacks, F.2    Pfeffer, M.3    Gao, Z.4    Curhan, G.5
  • 24
    • 33845700085 scopus 로고    scopus 로고
    • Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease
    • Levin A., Bakris G., Molitch M., et al. Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney Int 2007, 71:31-38.
    • (2007) Kidney Int , vol.71 , pp. 31-38
    • Levin, A.1    Bakris, G.2    Molitch, M.3
  • 25
    • 33645826282 scopus 로고    scopus 로고
    • Biology of vascular calcification in renal disease
    • Farzaneh-Far A., Shanahan C. Biology of vascular calcification in renal disease. Nephron Exp Nephrol 2005, 101:e134-e138.
    • (2005) Nephron Exp Nephrol , vol.101
    • Farzaneh-Far, A.1    Shanahan, C.2
  • 26
    • 34648834843 scopus 로고    scopus 로고
    • The fallacy of the calcium-phosphorus product
    • O'Neill W. The fallacy of the calcium-phosphorus product. Kidney Int 2007, 72:792-796.
    • (2007) Kidney Int , vol.72 , pp. 792-796
    • O'Neill, W.1
  • 27
    • 0027302528 scopus 로고
    • Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells
    • Shanahan C., Weissberg P., Metcalfe J. Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells. Circ Res 1993, 73:193-204.
    • (1993) Circ Res , vol.73 , pp. 193-204
    • Shanahan, C.1    Weissberg, P.2    Metcalfe, J.3
  • 28
    • 0034730291 scopus 로고    scopus 로고
    • Phosphate regulation of vascular smooth muscle cell calcification
    • Jono S., McKee M., Murry C., et al. Phosphate regulation of vascular smooth muscle cell calcification. Circ Res 2000, 87:E10-E17.
    • (2000) Circ Res , vol.87
    • Jono, S.1    McKee, M.2    Murry, C.3
  • 29
    • 0033774013 scopus 로고    scopus 로고
    • Prevalence and clinical consequences of elevated Ca × P product in hemodialysis patients
    • Block G. Prevalence and clinical consequences of elevated Ca × P product in hemodialysis patients. Clin Nephrol 2000, 54:318-324.
    • (2000) Clin Nephrol , vol.54 , pp. 318-324
    • Block, G.1
  • 30
    • 0035824898 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
    • Steitz S., Speer M., Curinga G., et al. Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res 2001, 89:1147-1154.
    • (2001) Circ Res , vol.89 , pp. 1147-1154
    • Steitz, S.1    Speer, M.2    Curinga, G.3
  • 31
    • 33646136895 scopus 로고    scopus 로고
    • Chemical and hormonal determinants of vascular calcification in vitro
    • Lomashvili K., Garg P., O'Neill W. Chemical and hormonal determinants of vascular calcification in vitro. Kidney Int 2006, 69:1464-1470.
    • (2006) Kidney Int , vol.69 , pp. 1464-1470
    • Lomashvili, K.1    Garg, P.2    O'Neill, W.3
  • 32
    • 2542471518 scopus 로고    scopus 로고
    • Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin
    • Lomashvili K., Cobbs S., Hennigar R., Hardcastle K., O'Neill W. Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. J Am Soc Nephrol 2004, 15:1392-1401.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1392-1401
    • Lomashvili, K.1    Cobbs, S.2    Hennigar, R.3    Hardcastle, K.4    O'Neill, W.5
  • 33
    • 0033524663 scopus 로고    scopus 로고
    • Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin
    • Wada T., McKee M., Steitz S., Giachelli C. Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res 1999, 84:166-178.
    • (1999) Circ Res , vol.84 , pp. 166-178
    • Wada, T.1    McKee, M.2    Steitz, S.3    Giachelli, C.4
  • 34
    • 67349171514 scopus 로고    scopus 로고
    • Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin
    • El-Abbadi M., Pai A., Leaf E., et al. Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin. Kidney Int 2009, 75:1297-1307.
    • (2009) Kidney Int , vol.75 , pp. 1297-1307
    • El-Abbadi, M.1    Pai, A.2    Leaf, E.3
  • 35
    • 65249154077 scopus 로고    scopus 로고
    • Phosphorus overload and PTH induce aortic expression of Runx2 in experimental uraemia
    • Graciolli F., Neves K., dos Reis L., et al. Phosphorus overload and PTH induce aortic expression of Runx2 in experimental uraemia. Nephrol Dial Transplant 2009, 24:1416-1421.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1416-1421
    • Graciolli, F.1    Neves, K.2    dos Reis, L.3
  • 36
    • 64249157371 scopus 로고    scopus 로고
    • Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries
    • Speer M., Yang H., Brabb T., et al. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circ Res 2009, 104:733-741.
    • (2009) Circ Res , vol.104 , pp. 733-741
    • Speer, M.1    Yang, H.2    Brabb, T.3
  • 37
    • 55449101447 scopus 로고    scopus 로고
    • Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis
    • Shroff R., McNair R., Figg N., et al. Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis. Circulation 2008, 118:1748-1757.
    • (2008) Circulation , vol.118 , pp. 1748-1757
    • Shroff, R.1    McNair, R.2    Figg, N.3
  • 38
    • 7044260650 scopus 로고    scopus 로고
    • Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis
    • Kaden J., Bickelhaupt S., Grobholz R., et al. Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis. J Heart Valve Dis 2004, 13:560-566.
    • (2004) J Heart Valve Dis , vol.13 , pp. 560-566
    • Kaden, J.1    Bickelhaupt, S.2    Grobholz, R.3
  • 39
    • 0037341318 scopus 로고    scopus 로고
    • Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification
    • Tyson K., Reynolds J., McNair R., Zhang Q., Weissberg P., Shanahan C. Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification. Arterioscler Thromb Vasc Biol 2003, 23:489-494.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 489-494
    • Tyson, K.1    Reynolds, J.2    McNair, R.3    Zhang, Q.4    Weissberg, P.5    Shanahan, C.6
  • 40
    • 0037337818 scopus 로고    scopus 로고
    • Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels
    • Moe S., Duan D., Doehle B., O'Neill K., Chen N. Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels. Kidney Int 2003, 63:1003-1011.
    • (2003) Kidney Int , vol.63 , pp. 1003-1011
    • Moe, S.1    Duan, D.2    Doehle, B.3    O'Neill, K.4    Chen, N.5
  • 41
    • 77950612644 scopus 로고    scopus 로고
    • Ultrastructural analysis of vascular calcifications in uremia
    • Schlieper G., Aretz A., Verberckmoes S., et al. Ultrastructural analysis of vascular calcifications in uremia. J Am Soc Nephrol 2010, 21:689-696.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 689-696
    • Schlieper, G.1    Aretz, A.2    Verberckmoes, S.3
  • 44
    • 0032446940 scopus 로고    scopus 로고
    • Na+-dependent phosphate cotransporters: the NaPi protein families
    • Werner A., Dehmelt L., Nalbant P. Na+-dependent phosphate cotransporters: the NaPi protein families. J Exp Biol 1998, 201:3135-3142.
    • (1998) J Exp Biol , vol.201 , pp. 3135-3142
    • Werner, A.1    Dehmelt, L.2    Nalbant, P.3
  • 45
    • 0032484615 scopus 로고    scopus 로고
    • Immunodetection of a type III sodium-dependent phosphate cotransporter in tissues and OK cells
    • Boyer C., Baines A., Beaulieu E., Béliveau R. Immunodetection of a type III sodium-dependent phosphate cotransporter in tissues and OK cells. Biochim Biophys Acta 1998, 1368:73-83.
    • (1998) Biochim Biophys Acta , vol.1368 , pp. 73-83
    • Boyer, C.1    Baines, A.2    Beaulieu, E.3    Béliveau, R.4
  • 46
    • 0028341123 scopus 로고
    • Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters
    • Kavanaugh M., Miller D., Zhang W., et al. Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters. Proc Natl Acad Sci U S A 1994, 91:7071-7075.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7071-7075
    • Kavanaugh, M.1    Miller, D.2    Zhang, W.3
  • 47
    • 0038005392 scopus 로고    scopus 로고
    • Characterization of an in vitro model of calcification in retinal pigmented epithelial cells
    • Sugitani H., Wachi H., Murata H., Sato F., Mecham R., Seyama Y. Characterization of an in vitro model of calcification in retinal pigmented epithelial cells. J Atheroscler Thromb 2003, 10:48-56.
    • (2003) J Atheroscler Thromb , vol.10 , pp. 48-56
    • Sugitani, H.1    Wachi, H.2    Murata, H.3    Sato, F.4    Mecham, R.5    Seyama, Y.6
  • 48
    • 0036406957 scopus 로고    scopus 로고
    • Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells
    • Chen N., O'Neill K., Duan D., Moe S. Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells. Kidney Int 2002, 62:1724-1731.
    • (2002) Kidney Int , vol.62 , pp. 1724-1731
    • Chen, N.1    O'Neill, K.2    Duan, D.3    Moe, S.4
  • 49
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X., Yang H., Giachelli C. Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 2006, 98:905-912.
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.2    Giachelli, C.3
  • 50
    • 34247339631 scopus 로고    scopus 로고
    • Characterization of phosphate transport in rat vascular smooth muscle cells: implications for vascular calcification
    • Villa-Bellosta R., Bogaert Y., Levi M., Sorribas V. Characterization of phosphate transport in rat vascular smooth muscle cells: implications for vascular calcification. Arterioscler Thromb Vasc Biol 2007, 27:1030-1036.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1030-1036
    • Villa-Bellosta, R.1    Bogaert, Y.2    Levi, M.3    Sorribas, V.4
  • 51
    • 0018792450 scopus 로고
    • Structure-activity relationship of inhibitors of hydroxyapatite formation
    • Williams G., Sallis J. Structure-activity relationship of inhibitors of hydroxyapatite formation. Biochem J 1979, 184:181-184.
    • (1979) Biochem J , vol.184 , pp. 181-184
    • Williams, G.1    Sallis, J.2
  • 52
    • 0014759515 scopus 로고
    • The inhibitory effect of phosphonates on the formation of calcium phosphate crystals in vitro and on aortic and kidney calcification in vivo
    • Fleisch H., Russell R., Bisaz S., Mühlbauer R., Williams D. The inhibitory effect of phosphonates on the formation of calcium phosphate crystals in vitro and on aortic and kidney calcification in vivo. Eur J Clin Invest 1970, 1:12-18.
    • (1970) Eur J Clin Invest , vol.1 , pp. 12-18
    • Fleisch, H.1    Russell, R.2    Bisaz, S.3    Mühlbauer, R.4    Williams, D.5
  • 53
    • 65549090151 scopus 로고    scopus 로고
    • Phosphonoformic acid prevents vascular smooth muscle cell calcification by inhibiting calcium-phosphate deposition
    • Villa-Bellosta R., Sorribas V. Phosphonoformic acid prevents vascular smooth muscle cell calcification by inhibiting calcium-phosphate deposition. Arterioscler Thromb Vasc Biol 2009, 29:761-766.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 761-766
    • Villa-Bellosta, R.1    Sorribas, V.2
  • 54
    • 70349576584 scopus 로고    scopus 로고
    • Vascular smooth muscle cell calcification and SLC20 inorganic phosphate transporters: effects of PDGF, TNF-alpha, and Pi
    • Villa-Bellosta R., Levi M., Sorribas V. Vascular smooth muscle cell calcification and SLC20 inorganic phosphate transporters: effects of PDGF, TNF-alpha, and Pi. Pflugers Arch 2009, 458:1151-1161.
    • (2009) Pflugers Arch , vol.458 , pp. 1151-1161
    • Villa-Bellosta, R.1    Levi, M.2    Sorribas, V.3
  • 55
    • 73649138204 scopus 로고    scopus 로고
    • Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1
    • Festing M., Speer M., Yang H., Giachelli C. Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis 2009, 47:858-863.
    • (2009) Genesis , vol.47 , pp. 858-863
    • Festing, M.1    Speer, M.2    Yang, H.3    Giachelli, C.4
  • 56
    • 40949158527 scopus 로고    scopus 로고
    • BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells
    • Li X., Yang H., Giachelli C. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis 2008, 199:271-277.
    • (2008) Atherosclerosis , vol.199 , pp. 271-277
    • Li, X.1    Yang, H.2    Giachelli, C.3
  • 57
    • 33748428184 scopus 로고    scopus 로고
    • The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells
    • Chen N., Duan D., O'Neill K., et al. The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells. Kidney Int 2006, 70:1046-1053.
    • (2006) Kidney Int , vol.70 , pp. 1046-1053
    • Chen, N.1    Duan, D.2    O'Neill, K.3
  • 59
    • 40949152051 scopus 로고    scopus 로고
    • Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells
    • Johnson K., Polewski M., Terkeltaub R. Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res 2008, 102:529-537.
    • (2008) Circ Res , vol.102 , pp. 529-537
    • Johnson, K.1    Polewski, M.2    Terkeltaub, R.3
  • 60
    • 0037317032 scopus 로고    scopus 로고
    • Transglutaminases: crosslinking enzymes with pleiotropic functions
    • Lorand L., Graham R. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 2003, 4:140-156.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 140-156
    • Lorand, L.1    Graham, R.2
  • 61
    • 77749264513 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia
    • Prosdocimo D., Wyler S., Romani A., O'Neill W., Dubyak G. Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia. Am J Physiol Cell Physiol 2010, 298:C702-C713.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Prosdocimo, D.1    Wyler, S.2    Romani, A.3    O'Neill, W.4    Dubyak, G.5
  • 62
    • 49049083428 scopus 로고    scopus 로고
    • Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification
    • Huang M., Sage A., Lu J., Demer L., Tintut Y. Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification. Biochem Biophys Res Commun 2008, 374:553-558.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 553-558
    • Huang, M.1    Sage, A.2    Lu, J.3    Demer, L.4    Tintut, Y.5
  • 63
    • 39049096394 scopus 로고    scopus 로고
    • Mechanisms of vascular calcification in chronic kidney disease
    • Moe S., Chen N. Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol 2008, 19:213-216.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 213-216
    • Moe, S.1    Chen, N.2
  • 64
    • 20844433032 scopus 로고    scopus 로고
    • Fetuin-A and extraosseous calcification in uremia
    • Ketteler M. Fetuin-A and extraosseous calcification in uremia. Curr Opin Nephrol Hypertens 2005, 14:337-342.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 337-342
    • Ketteler, M.1
  • 65
    • 67649397446 scopus 로고    scopus 로고
    • Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease
    • Silverstein D. Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease. Pediatr Nephrol 2009, 24:1445-1452.
    • (2009) Pediatr Nephrol , vol.24 , pp. 1445-1452
    • Silverstein, D.1
  • 66
    • 67649447069 scopus 로고    scopus 로고
    • Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK
    • Tanikawa T., Okada Y., Tanikawa R., Tanaka Y. Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK. J Vasc Res 2009, 46:572-580.
    • (2009) J Vasc Res , vol.46 , pp. 572-580
    • Tanikawa, T.1    Okada, Y.2    Tanikawa, R.3    Tanaka, Y.4
  • 67
    • 14544283020 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD
    • Reynolds J., Joannides A., Skepper J., et al. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 2004, 15:2857-2867.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2857-2867
    • Reynolds, J.1    Joannides, A.2    Skepper, J.3
  • 68
    • 75149140991 scopus 로고    scopus 로고
    • Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification
    • Shroff R., McNair R., Skepper J., et al. Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification. J Am Soc Nephrol 2010, 21:103-112.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 103-112
    • Shroff, R.1    McNair, R.2    Skepper, J.3
  • 69
    • 33646799150 scopus 로고    scopus 로고
    • Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway
    • Son B., Kozaki K., Iijima K., et al. Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway. Circ Res 2006, 98:1024-1031.
    • (2006) Circ Res , vol.98 , pp. 1024-1031
    • Son, B.1    Kozaki, K.2    Iijima, K.3
  • 70
    • 0038051797 scopus 로고    scopus 로고
    • Receptor tyrosine kinase Axl modulates the osteogenic differentiation of pericytes
    • Collett G., Wood A., Alexander M., et al. Receptor tyrosine kinase Axl modulates the osteogenic differentiation of pericytes. Circ Res 2003, 92:1123-1129.
    • (2003) Circ Res , vol.92 , pp. 1123-1129
    • Collett, G.1    Wood, A.2    Alexander, M.3
  • 71
    • 33846103421 scopus 로고    scopus 로고
    • Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells
    • Son B., Kozaki K., Iijima K., et al. Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. Eur J Pharmacol 2007, 556:1-8.
    • (2007) Eur J Pharmacol , vol.556 , pp. 1-8
    • Son, B.1    Kozaki, K.2    Iijima, K.3
  • 72
    • 54049090502 scopus 로고    scopus 로고
    • Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization
    • Ewence A., Bootman M., Roderick H., et al. Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization. Circ Res 2008, 103:e28-e34.
    • (2008) Circ Res , vol.103
    • Ewence, A.1    Bootman, M.2    Roderick, H.3
  • 73
    • 79551568395 scopus 로고    scopus 로고
    • Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro
    • In press.
    • Sage A, Lu J, Tintut Y, Demer L. Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney Int. In press.
    • Kidney Int
    • Sage, A.1    Lu, J.2    Tintut, Y.3    Demer, L.4
  • 74
    • 0037385471 scopus 로고    scopus 로고
    • Cell characterization of porcine aortic valve and decellularized leaflets repopulated with aortic valve interstitial cells: the VESALIO Project (Vitalitate Exornatum Succedaneum Aorticum Labore Ingenioso Obtenibitur)
    • Bertipaglia B., Ortolani F., Petrelli L., et al. Cell characterization of porcine aortic valve and decellularized leaflets repopulated with aortic valve interstitial cells: the VESALIO Project (Vitalitate Exornatum Succedaneum Aorticum Labore Ingenioso Obtenibitur). Ann Thorac Surg 2003, 75:1274-1282.
    • (2003) Ann Thorac Surg , vol.75 , pp. 1274-1282
    • Bertipaglia, B.1    Ortolani, F.2    Petrelli, L.3
  • 75
    • 24344435113 scopus 로고    scopus 로고
    • Calcification of human valve interstitial cells is dependent on alkaline phosphatase activity
    • Mathieu P., Voisine P., Pépin A., Shetty R., Savard N., Dagenais F. Calcification of human valve interstitial cells is dependent on alkaline phosphatase activity. J Heart Valve Dis 2005, 14:353-357.
    • (2005) J Heart Valve Dis , vol.14 , pp. 353-357
    • Mathieu, P.1    Voisine, P.2    Pépin, A.3    Shetty, R.4    Savard, N.5    Dagenais, F.6
  • 76
    • 57549110622 scopus 로고    scopus 로고
    • Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate
    • Rattazzi M., Iop L., Faggin E., et al. Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate. Arterioscler Thromb Vasc Biol 2008, 28:2165-2172.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2165-2172
    • Rattazzi, M.1    Iop, L.2    Faggin, E.3
  • 77
    • 0033057678 scopus 로고    scopus 로고
    • Identification and characterization of calcifying valve cells from human and canine aortic valves
    • Mohler Er, Chawla M., Chang A., et al. Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis 1999, 8:254-260.
    • (1999) J Heart Valve Dis , vol.8 , pp. 254-260
    • Mohler, E.1    Chawla, M.2    Chang, A.3
  • 79
    • 0028886929 scopus 로고
    • Calcified deposit formation in intimal thickenings of the human aorta
    • Bobryshev Y., Lord R., Warren B. Calcified deposit formation in intimal thickenings of the human aorta. Atherosclerosis 1995, 118:9-21.
    • (1995) Atherosclerosis , vol.118 , pp. 9-21
    • Bobryshev, Y.1    Lord, R.2    Warren, B.3
  • 80
    • 72449195175 scopus 로고    scopus 로고
    • Elastin degradation accelerates phosphate-induced mineralization of vascular smooth muscle cells
    • Hosaka N., Mizobuchi M., Ogata H., et al. Elastin degradation accelerates phosphate-induced mineralization of vascular smooth muscle cells. Calcif Tissue Int 2009, 85:523-529.
    • (2009) Calcif Tissue Int , vol.85 , pp. 523-529
    • Hosaka, N.1    Mizobuchi, M.2    Ogata, H.3
  • 81
    • 42149157247 scopus 로고    scopus 로고
    • Sequential activation of matrix metalloproteinase 9 and transforming growth factor beta in arterial elastocalcinosis
    • Bouvet C., Moreau S., Blanchette J., de Blois D., Moreau P. Sequential activation of matrix metalloproteinase 9 and transforming growth factor beta in arterial elastocalcinosis. Arterioscler Thromb Vasc Biol 2008, 28:856-862.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 856-862
    • Bouvet, C.1    Moreau, S.2    Blanchette, J.3    de Blois, D.4    Moreau, P.5
  • 82
    • 0016363786 scopus 로고
    • Calcium binding to elastin
    • Rucker R. Calcium binding to elastin. Adv Exp Med Biol 1974, 48:185-209.
    • (1974) Adv Exp Med Biol , vol.48 , pp. 185-209
    • Rucker, R.1
  • 83
    • 22144457065 scopus 로고    scopus 로고
    • Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells
    • Simionescu A., Philips K., Vyavahare N. Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells. Biochem Biophys Res Commun 2005, 334:524-532.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 524-532
    • Simionescu, A.1    Philips, K.2    Vyavahare, N.3
  • 84
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin C., Miyazono K., ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997, 390:465-471.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.1    Miyazono, K.2    ten Dijke, P.3
  • 85
    • 0034460993 scopus 로고    scopus 로고
    • Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
    • Lee K., Kim H., Li Q., et al. Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol Cell Biol 2000, 20:8783-8792.
    • (2000) Mol Cell Biol , vol.20 , pp. 8783-8792
    • Lee, K.1    Kim, H.2    Li, Q.3
  • 86
    • 70349396606 scopus 로고    scopus 로고
    • Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials
    • Navaneethan S., Palmer S., Craig J., Elder G., Strippoli G. Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials. Am J Kidney Dis 2009, 54:619-637.
    • (2009) Am J Kidney Dis , vol.54 , pp. 619-637
    • Navaneethan, S.1    Palmer, S.2    Craig, J.3    Elder, G.4    Strippoli, G.5
  • 87
    • 77950810562 scopus 로고    scopus 로고
    • Oral phosphate binders in patients with kidney failure
    • Tonelli M., Pannu N., Manns B. Oral phosphate binders in patients with kidney failure. N Engl J Med 2010, 362:1312-1324.
    • (2010) N Engl J Med , vol.362 , pp. 1312-1324
    • Tonelli, M.1    Pannu, N.2    Manns, B.3
  • 88
    • 62249090222 scopus 로고    scopus 로고
    • Targeting vascular calcification: softening-up a hard target
    • Kapustin A., Shanahan C. Targeting vascular calcification: softening-up a hard target. Curr Opin Pharmacol 2009, 9:84-89.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 84-89
    • Kapustin, A.1    Shanahan, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.