-
1
-
-
23944523430
-
The emerging role of the PI3-K-Akt pathway in prostate cancer progression
-
15724144
-
Li L Ittmann MM Ayala G: The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis. 2005;8(2):108-18. 15724144 10.1038/sj.pcan.4500776
-
(2005)
Prostate Cancer Prostatic Dis
, vol.8
, Issue.2
, pp. 108-118
-
-
Li, L.1
Ittmann, M.M.2
Ayala, G.3
-
2
-
-
0042847224
-
Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation
-
12874217
-
Na SY Patra A Scheuring Y: Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. J Immunol. 2003;171(3):1285-96. 12874217
-
(2003)
J Immunol
, vol.171
, Issue.3
, pp. 1285-1296
-
-
Na, S.Y.1
Patra, A.2
Scheuring, Y.3
-
3
-
-
80053909808
-
Akt Fine-tunes NF-ΚB-dependent gene expression during T cell activation
-
21862580, 3195567
-
Cheng J Phong B Wilson DC: Akt Fine-tunes NF-ΚB-dependent gene expression during T cell activation. J Biol Chem. 2011;286(41):36076-85. 21862580 10.1074/jbc.M111.259549 3195567
-
(2011)
J Biol Chem
, vol.286
, Issue.41
, pp. 36076-36085
-
-
Cheng, J.1
Phong, B.2
Wilson, D.C.3
-
4
-
-
0037025948
-
CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly
-
12163562, 2193932
-
Jones RG Elford AR Parsons MJ: CD28-dependent Activation of Protein Kinase B/Akt Blocks Fas-mediated Apoptosis by Preventing Death-inducing Signaling Complex Assembly. J Exp Med. 2002;196(3):335-48. 12163562 10.1084/jem.20020307 2193932
-
(2002)
J Exp Med
, vol.196
, Issue.3
, pp. 335-348
-
-
Jones, R.G.1
Elford, A.R.2
Parsons, M.J.3
-
5
-
-
0035221568
-
Akt provides the CD28 costimulatory signal for upregulation of IL-2 and IFN-gamma but not Th2 cytokines
-
11135576
-
Kane LP Andres PG Howland KC: Akt provides the CD28 costimulatory signal for upregulation of IL-2 and IFN-gamma but not Th2 cytokines. Nat Immunol. 2001;2(1):37-44. 11135576 10.1038/83144
-
(2001)
Nat Immunol
, vol.2
, Issue.1
, pp. 37-44
-
-
Kane, L.P.1
Andres, P.G.2
Howland, K.C.3
-
6
-
-
0033519453
-
Induction of NF-kappaB by the Akt/PKB kinase
-
10359702
-
Kane LP Shapiro VS Stokoe D: Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol. 1999;9(11):601-604. 10359702 10.1016/S0960-9822(99)80265-6
-
(1999)
Curr Biol
, vol.9
, Issue.11
, pp. 601-604
-
-
Kane, L.P.1
Shapiro, V.S.2
Stokoe, D.3
-
7
-
-
1842581764
-
Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins
-
15067058
-
Patra AK Na SY Bommhardt U: Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins. J Immunol. 2004;172(8):4812-20. 15067058
-
(2004)
J Immunol
, vol.172
, Issue.8
, pp. 4812-4820
-
-
Patra, A.K.1
Na, S.Y.2
Bommhardt, U.3
-
8
-
-
84876721681
-
Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells
-
23389849, 3685436
-
Pande S Browne G Padmanabhan S: Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells. J Cell Physiol. 2013;228(8):1784-92. 23389849 10.1002/jcp.24339 3685436
-
(2013)
J Cell Physiol
, vol.228
, Issue.8
, pp. 1784-1792
-
-
Pande, S.1
Browne, G.2
Padmanabhan, S.3
-
9
-
-
84869872964
-
Novel Foxo1-dependent transcriptional programs control T(reg) cell function
-
23135404, 3771531
-
Ouyang W Liao W Luo CT: Novel Foxo1-dependent transcriptional programs control T(reg) cell function. Nature. 2012;491(7425):554-9. 23135404 10.1038/nature11581 3771531
-
(2012)
Nature
, vol.491
, Issue.7425
, pp. 554-559
-
-
Ouyang, W.1
Liao, W.2
Luo, C.T.3
-
10
-
-
79951745387
-
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
-
21295499, 3052433
-
Macintyre AN Finlay D Preston G: Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. Immunity. 2011;34(2):224-36. 21295499 10.1016/j.immuni.2011.01.012 3052433
-
(2011)
Immunity
, vol.34
, Issue.2
, pp. 224-236
-
-
Macintyre, A.N.1
Finlay, D.2
Preston, G.3
-
11
-
-
78049268109
-
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
-
20823247, 2944719
-
Hand TW Cui W Jung YW: Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proc Natl Acad Sci U S A. 2010;107(38):16601-6. 20823247 10.1073/pnas.1003457107 2944719
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.38
, pp. 16601-16606
-
-
Hand, T.W.1
Cui, W.2
Jung, Y.W.3
-
12
-
-
33847345465
-
CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B
-
17312138
-
Saibil SD Jones RG Deenick EK: CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J Immunol. 2007;178(5):2932-9. 17312138
-
(2007)
J Immunol
, vol.178
, Issue.5
, pp. 2932-2939
-
-
Saibil, S.D.1
Jones, R.G.2
Deenick, E.K.3
-
13
-
-
19944433628
-
Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
-
15456405, 1134710
-
Barnett SF Defeo-Jones D Fu S: Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors. Biochem J. 2005;385(Pt 2):399-408. 15456405 10.1042/BJ20041140 1134710
-
(2005)
Biochem J
, vol.385
, pp. 399-408
-
-
Barnett, S.F.1
Defeo-Jones, D.2
Fu, S.3
-
14
-
-
17144392548
-
The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation
-
15853641
-
Barnett SF Bilodeau MT Lindsley CW: The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation. Curr Top Med Chem. 2005;5(2):109-25. 15853641 10.2174/1568026053507714
-
(2005)
Curr Top Med Chem
, vol.5
, Issue.2
, pp. 109-125
-
-
Barnett, S.F.1
Bilodeau, M.T.2
Lindsley, C.W.3
-
15
-
-
20044370874
-
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
-
15713898
-
DeFeo-Jones D Barnett SF Fu S: Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members. Mol Cancer Ther. 2005;4(2):271-9. 15713898
-
(2005)
Mol Cancer Ther
, vol.4
, Issue.2
, pp. 271-279
-
-
DeFeo-Jones, D.1
Barnett, S.F.2
Fu, S.3
-
16
-
-
19944431003
-
Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors
-
15664853
-
Lindsley CW Zhao Z Leister WH: Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors. Bioorg Med Chem Lett. 2005;15(3):761-4. 15664853 10.1016/j.bmcl.2004.11.011
-
(2005)
Bioorg Med Chem Lett
, vol.15
, Issue.3
, pp. 761-764
-
-
Lindsley, C.W.1
Zhao, Z.2
Leister, W.H.3
-
17
-
-
2142646543
-
A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse
-
15100285
-
Kane LP Mollenauer MN Weiss A: A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse. J Immunol. 2004;172(9):5441-9. 15100285
-
(2004)
J Immunol
, vol.172
, Issue.9
, pp. 5441-5449
-
-
Kane, L.P.1
Mollenauer, M.N.2
Weiss, A.3
-
18
-
-
33644772836
-
CARMA1 is required for Akt-mediated NF-kappaB activation in T cells
-
16508008, 1430296
-
Narayan P Holt B Tosti R: CARMA1 is required for Akt-mediated NF-kappaB activation in T cells. Mol Cell Biol. 2006;26(6):2327-36. 16508008 10.1128/MCB.26.6.2327-2336.2006 1430296
-
(2006)
Mol Cell Biol
, vol.26
, Issue.6
, pp. 2327-2336
-
-
Narayan, P.1
Holt, B.2
Tosti, R.3
-
19
-
-
0020602877
-
Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells
-
6193236, 2187090
-
Kaye J Porcelli S Tite J: Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells. J Exp Med. 1983;158(3):836-56. 6193236 10.1084/jem.158.3.836 2187090
-
(1983)
J Exp Med
, vol.158
, Issue.3
, pp. 836-856
-
-
Kaye, J.1
Porcelli, S.2
Tite, J.3
-
20
-
-
49949103770
-
Efficiency analysis of competing tests for finding differentially expressed genes in lung adenocarcinoma
-
19259419, 2623303
-
Jordan R Patel S Hu H: Efficiency analysis of competing tests for finding differentially expressed genes in lung adenocarcinoma. Cancer Inform. 2008;6:389-421. 19259419 2623303
-
(2008)
Cancer Inform
, vol.6
, pp. 389-421
-
-
Jordan, R.1
Patel, S.2
Hu, H.3
-
21
-
-
13244270483
-
caGEDA: a web application for the integrated analysis of global gene expression patterns in cancer
-
16323966
-
Patel S Lyons-Weiler J: caGEDA: a web application for the integrated analysis of global gene expression patterns in cancer. Appl Bioinformatics. 2004;3(1):49-62. 16323966 10.2165/00822942-200403010-00007
-
(2004)
Appl Bioinformatics
, vol.3
, Issue.1
, pp. 49-62
-
-
Patel, S.1
Lyons-Weiler, J.2
-
22
-
-
34548400259
-
A systems biology approach for pathway level analysis
-
17785539, 1987343
-
Draghici S Khatri P Tarca AL: A systems biology approach for pathway level analysis. Genome Res. 2007;17(10):1537-45. 17785539 10.1101/gr.6202607 1987343
-
(2007)
Genome Res
, vol.17
, Issue.10
, pp. 1537-1545
-
-
Draghici, S.1
Khatri, P.2
Tarca, A.L.3
-
23
-
-
77954364953
-
Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data
-
20215436, 2887972
-
Essaghir A Toffalini F Knoops L: Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data. Nucleic Acids Res. 2010;38(11):e120. 20215436 10.1093/nar/gkq149 2887972
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.11
, pp. e120
-
-
Essaghir, A.1
Toffalini, F.2
Knoops, L.3
-
24
-
-
58849120491
-
Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition
-
19166270, 2628406
-
Calleja V Laguerre M Parker PJ: Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. PLoS Biol. 2009;7(1):e17. 19166270 10.1371/journal.pbio.1000017 2628406
-
(2009)
PLoS Biol
, vol.7
, Issue.1
, pp. e17
-
-
Calleja, V.1
Laguerre, M.2
Parker, P.J.3
-
25
-
-
34548453703
-
Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells
-
17563061
-
Logie L Ruiz-Alcaraz AJ Keane M: Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells. Diabetes. 2007;56(9):2218-27. 17563061 10.2337/db07-0343
-
(2007)
Diabetes
, vol.56
, Issue.9
, pp. 2218-2227
-
-
Logie, L.1
Ruiz-Alcaraz, A.J.2
Keane, M.3
-
26
-
-
36549040859
-
The selectivity of protein kinase inhibitors: a further update
-
17850214, 2267365
-
Bain J Plater L Elliott M: The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007;408(3):297-315. 17850214 10.1042/BJ20070797 2267365
-
(2007)
Biochem J
, vol.408
, Issue.3
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
-
27
-
-
0031971539
-
Functional analysis of CD82 in the early phase of T cell activation: roles in cell adhesion and signal transduction
-
9565351
-
Shibagaki N Hanada K Yamaguchi S: Functional analysis of CD82 in the early phase of T cell activation: roles in cell adhesion and signal transduction. Eur J Immunol. 1998;28(4):1125-33. 9565351 10.1002/(SICI)1521-4141(199804)28:04&<1125::AID-IMMU1125&>3.0.CO;2-C
-
(1998)
Eur J Immunol
, vol.28
, Issue.4
, pp. 1125-1133
-
-
Shibagaki, N.1
Hanada, K.2
Yamaguchi, S.3
-
28
-
-
0029055433
-
CD82, member of the tetra-span-transmembrane protein family, is a costimulatory protein for T cell activation
-
7602090
-
Lebel-Binay S Lagaudrière C Fradelizi D: CD82, member of the tetra-span-transmembrane protein family, is a costimulatory protein for T cell activation. J Immunol. 1995;155(1):101-10. 7602090
-
(1995)
J Immunol
, vol.155
, Issue.1
, pp. 101-110
-
-
Lebel-Binay, S.1
Lagaudrière, C.2
Fradelizi, D.3
-
29
-
-
0025878925
-
Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone
-
1711975
-
Xia MQ Tone M Packman L: Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. Eur J Immunol. 1991;21(7):1677-84. 1711975 10.1002/eji.1830210714
-
(1991)
Eur J Immunol
, vol.21
, Issue.7
, pp. 1677-1684
-
-
Xia, M.Q.1
Tone, M.2
Packman, L.3
-
30
-
-
0028870425
-
Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes
-
7718516
-
Rowan WC Hale G Tite JP: Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. Int Immunol. 1995;7(1):69-77. 7718516 10.1093/intimm/7.1.69
-
(1995)
Int Immunol
, vol.7
, Issue.1
, pp. 69-77
-
-
Rowan, W.C.1
Hale, G.2
Tite, J.P.3
-
31
-
-
33746836125
-
CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells
-
16797237
-
Watanabe T Masuyama J Sohma Y: CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells. Clin Immunol. 2006;120(3):247-59. 16797237 10.1016/j.clim.2006.05.006
-
(2006)
Clin Immunol
, vol.120
, Issue.3
, pp. 247-259
-
-
Watanabe, T.1
Masuyama, J.2
Sohma, Y.3
-
32
-
-
37549028779
-
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
-
18092230
-
Jastrzebski K Hannan KM Tchoubrieva EB: Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. Growth Factors. 2007;25(4):209-26. 18092230 10.1080/08977190701779101
-
(2007)
Growth Factors
, vol.25
, Issue.4
, pp. 209-226
-
-
Jastrzebski, K.1
Hannan, K.M.2
Tchoubrieva, E.B.3
-
33
-
-
46749134481
-
Gene expression profiling in women with breast cancer in a Saudi population
-
18382789
-
Bin Amer SM Maqbool Z Nirmal MS: Gene expression profiling in women with breast cancer in a Saudi population. Saudi Med J. 2008;29(4):507-13. 18382789
-
(2008)
Saudi Med J
, vol.29
, Issue.4
, pp. 507-513
-
-
Bin Amer, S.M.1
Maqbool, Z.2
Nirmal, M.S.3
-
34
-
-
76049086340
-
Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia
-
20116044, 2820177
-
Doherty L Sheen MR Vlachos A: Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010;86(2):222-8. 20116044 10.1016/j.ajhg.2009.12.015 2820177
-
(2010)
Am J Hum Genet
, vol.86
, Issue.2
, pp. 222-228
-
-
Doherty, L.1
Sheen, M.R.2
Vlachos, A.3
-
35
-
-
0025177034
-
Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a
-
2403926, 551645
-
Ziemiecki A Müller RG Fu XC: Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a. EMBO J. 1990;9(1):191-6. 2403926 551645
-
(1990)
EMBO J
, vol.9
, Issue.1
, pp. 191-196
-
-
Ziemiecki, A.1
Müller, R.G.2
Fu, X.C.3
-
36
-
-
78751580292
-
Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors
-
21040949
-
Artero-Castro A Castellvi J García A: Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors. Hum Pathol. 2011;42(2):194-203. 21040949 10.1016/j.humpath.2010.04.020
-
(2011)
Hum Pathol
, vol.42
, Issue.2
, pp. 194-203
-
-
Artero-Castro, A.1
Castellvi, J.2
García, A.3
-
37
-
-
80052970809
-
FoxO transcription factors; Regulation by AKT and 14-3-3 proteins
-
21708191
-
Tzivion G Dobson M Ramakrishnan G: FoxO transcription factors; Regulation by AKT and 14-3-3 proteins. Biochim Biophys Acta. 2011;1813(11):1938-45. 21708191 10.1016/j.bbamcr.2011.06.002
-
(2011)
Biochim Biophys Acta
, vol.1813
, Issue.11
, pp. 1938-1945
-
-
Tzivion, G.1
Dobson, M.2
Ramakrishnan, G.3
-
38
-
-
84866353412
-
FOXO transcription factors throughout T cell biology
-
22918467
-
Hedrick SM Hess Michelini R Doedens AL: FOXO transcription factors throughout T cell biology. Nat Rev Immunol. 2012;12(9):649-61. 22918467 10.1038/nri3278
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.9
, pp. 649-661
-
-
Hedrick, S.M.1
Hess Michelini, R.2
Doedens, A.L.3
-
39
-
-
79251541212
-
The extending network of FOXO transcriptional target genes
-
20673124
-
van der Vos KE Coffer PJ: The extending network of FOXO transcriptional target genes. Antioxid Redox Signal. 2011;14(4):579-92. 20673124 10.1089/ars.2010.3419
-
(2011)
Antioxid Redox Signal
, vol.14
, Issue.4
, pp. 579-592
-
-
van der Vos, K.E.1
Coffer, P.J.2
-
40
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
17254969, 1855089
-
Paik JH Kollipara R Chu G: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 2007;128(2):309-23. 17254969 10.1016/j.cell.2006.12.029 1855089
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
-
41
-
-
41049085574
-
Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors
-
18226221, 2268685
-
Terragni J Graham JR Adams KW: Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors. BMC Cell Biol. 2008;9:6. 18226221 10.1186/1471-2121-9-6 2268685
-
(2008)
BMC Cell Biol
, vol.9
, pp. 6
-
-
Terragni, J.1
Graham, J.R.2
Adams, K.W.3
-
42
-
-
79960716001
-
Akt signalling in health and disease
-
21620960
-
Hers I Vincent EE Tavare JM: Akt signalling in health and disease. Cell Signal. 2011;23(10):1515-27. 21620960 10.1016/j.cellsig.2011.05.004
-
(2011)
Cell Signal
, vol.23
, Issue.10
, pp. 1515-1527
-
-
Hers, I.1
Vincent, E.E.2
Tavare, J.M.3
-
43
-
-
34250788809
-
AKT/PKB signaling: navigating downstream
-
17604717, 2756685
-
Manning BD Cantley LC: AKT/PKB signaling: navigating downstream. Cell. 2007;129(7):1261-74. 17604717 10.1016/j.cell.2007.06.009 2756685
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
44
-
-
48849086912
-
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer
-
18652687, 2496917
-
Heinonen H Nieminen A Saarela M: Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer. BMC Genomics. 2008;9:348. 18652687 10.1186/1471-2164-9-348 2496917
-
(2008)
BMC Genomics
, vol.9
, pp. 348
-
-
Heinonen, H.1
Nieminen, A.2
Saarela, M.3
-
45
-
-
13244298415
-
Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway
-
15550386
-
Latres E Amini AR Amini AA: Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway. J Biol Chem. 2005;280(4):2737-44. 15550386 10.1074/jbc.M407517200
-
(2005)
J Biol Chem
, vol.280
, Issue.4
, pp. 2737-2744
-
-
Latres, E.1
Amini, A.R.2
Amini, A.A.3
-
46
-
-
54249141095
-
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
-
18577716, 2638731
-
Maciver NJ Jacobs SR Wieman HL: Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J Leukoc Biol. 2008;84(4):949-57. 18577716 10.1189/jlb.0108024 2638731
-
(2008)
J Leukoc Biol
, vol.84
, Issue.4
, pp. 949-957
-
-
Maciver, N.J.1
Jacobs, S.R.2
Wieman, H.L.3
-
47
-
-
0038578823
-
The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3
-
12670391
-
Kane LP Weiss A: The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunol Rev. 2003;192(1):7-20. 12670391 10.1034/j.1600-065X.2003.00008.x
-
(2003)
Immunol Rev
, vol.192
, Issue.1
, pp. 7-20
-
-
Kane, L.P.1
Weiss, A.2
-
48
-
-
81455135900
-
Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation
-
21987662, 3208080
-
Obar JJ Jellison ER Sheridan BS: Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. J Immunol. 2011;187(10):4967-78. 21987662 10.4049/jimmunol.1102335 3208080
-
(2011)
J Immunol
, vol.187
, Issue.10
, pp. 4967-4978
-
-
Obar, J.J.1
Jellison, E.R.2
Sheridan, B.S.3
-
49
-
-
43449134355
-
Distinct regulation of effector and memory T-cell differentiation
-
18362944
-
Kallies A: Distinct regulation of effector and memory T-cell differentiation. Immunol Cell Biol. 2008;86(4):325-32. 18362944 10.1038/icb.2008.16
-
(2008)
Immunol Cell Biol
, vol.86
, Issue.4
, pp. 325-332
-
-
Kallies, A.1
-
50
-
-
33846410668
-
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells
-
17190839, 2118424
-
Riou C Yassine-Diab B Van Grevenynghe J: Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells. J Exp Med. 2007;204(1):79-91. 17190839 10.1084/jem.20061681 2118424
-
(2007)
J Exp Med
, vol.204
, Issue.1
, pp. 79-91
-
-
Riou, C.1
Yassine-Diab, B.2
Van Grevenynghe, J.3
-
51
-
-
84860342013
-
Signal integration by Akt regulates CD8 T cell effector and memory differentiation
-
22467649, 3331885
-
Kim EH Sullivan JA Plisch EH: Signal integration by Akt regulates CD8 T cell effector and memory differentiation. J Immunol. 2012;188(9):4305-14. 22467649 10.4049/jimmunol.1103568 3331885
-
(2012)
J Immunol
, vol.188
, Issue.9
, pp. 4305-4314
-
-
Kim, E.H.1
Sullivan, J.A.2
Plisch, E.H.3
-
52
-
-
80052282364
-
AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer
-
21878679
-
Chan JC Hannan KM Riddell K: AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer. Sci Signal. 2011;4(188):ra56. 21878679 10.1126/scisignal.2001754
-
(2011)
Sci Signal
, vol.4
, Issue.188
, pp. ra56
-
-
Chan, J.C.1
Hannan, K.M.2
Riddell, K.3
-
53
-
-
78650085394
-
Foxo transcription factors control regulatory T cell development and function
-
21167754, 3034255
-
Kerdiles YM Stone EL Beisner DR: Foxo transcription factors control regulatory T cell development and function. Immunity. 2010;33(6):890-904. 21167754 10.1016/j.immuni.2010.12.002 3034255
-
(2010)
Immunity
, vol.33
, Issue.6
, pp. 890-904
-
-
Kerdiles, Y.M.1
Stone, E.L.2
Beisner, D.R.3
-
54
-
-
41149113441
-
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
-
18283119, 2275380
-
Haxhinasto S Mathis D Benoist C: The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J Exp Med. 2008;205(3):565-74. 18283119 10.1084/jem.20071477 2275380
-
(2008)
J Exp Med
, vol.205
, Issue.3
, pp. 565-574
-
-
Haxhinasto, S.1
Mathis, D.2
Benoist, C.3
-
55
-
-
45549098562
-
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
-
18509048, 2409380
-
Sauer S Bruno L Hertweck A: T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. Proc Natl Acad Sci U S A. 2008;105(22):7797-802. 18509048 10.1073/pnas.0800928105 2409380
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.22
, pp. 7797-7802
-
-
Sauer, S.1
Bruno, L.2
Hertweck, A.3
-
56
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
23021216, 3471363
-
Nie Z Hu G Wei G: c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell. 2012;151(1):68-79. 23021216 10.1016/j.cell.2012.08.033 3471363
-
(2012)
Cell
, vol.151
, Issue.1
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
-
57
-
-
17744400301
-
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
-
11250904, 145518
-
Boon K Caron HN van Asperen R: N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J. 2001;20(6):1383-93. 11250904 10.1093/emboj/20.6.1383 145518
-
(2001)
EMBO J
, vol.20
, Issue.6
, pp. 1383-1393
-
-
Boon, K.1
Caron, H.N.2
van Asperen, R.3
|