메뉴 건너뛰기




Volumn 33, Issue 25, 2014, Pages 3267-3276

MiR-508-5p regulates multidrug resistance of gastric cancer by targeting ABCB1 and ZNRD1

Author keywords

ABCB1; drug resistance; gastric cancer; miR 508 5p; ZNRD1

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 508 5P; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN ZNRD1; UNCLASSIFIED DRUG;

EID: 84908022850     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.297     Document Type: Article
Times cited : (165)

References (46)
  • 2
    • 79954524112 scopus 로고    scopus 로고
    • Mechanism of cell adaptation: When and how do cancer cells develop chemoresistance?
    • Fodale V, Pierobon M, Liotta L, Petricoin E. Mechanism of cell adaptation: when and how do cancer cells develop chemoresistance? Cancer J 2011; 17: 89-95.
    • (2011) Cancer J , vol.17 , pp. 89-95
    • Fodale, V.1    Pierobon, M.2    Liotta, L.3    Petricoin, E.4
  • 4
    • 84874944420 scopus 로고    scopus 로고
    • P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel
    • Hendrikx JJ, Lagas JS, Rosing H, Schellens JH, Beijnen JH, Schinkel AH. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. Int J Cancer 2012; 132: 2439-2447.
    • (2012) Int J Cancer , vol.132 , pp. 2439-2447
    • Hendrikx, J.J.1    Lagas, J.S.2    Rosing, H.3    Schellens, J.H.4    Beijnen, J.H.5    Schinkel, A.H.6
  • 5
    • 84869094020 scopus 로고    scopus 로고
    • Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells
    • Zhu H, Liu Z, Tang L, Liu J, Zhou M, Xie F et al. Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells. Eur J Pharmacol 2012; 696: 43-53.
    • (2012) Eur J Pharmacol , vol.696 , pp. 43-53
    • Zhu, H.1    Liu, Z.2    Tang, L.3    Liu, J.4    Zhou, M.5    Xie, F.6
  • 6
    • 84871081930 scopus 로고    scopus 로고
    • Overexpression of lung resistance-related protein and P-glycoprotein and response to induction chemotherapy in acute myelogenous leukemia
    • Tsuji K, Wang YH, Takanashi M, Odajima T, Lee GA, Sugimori H et al. Overexpression of lung resistance-related protein and P-glycoprotein and response to induction chemotherapy in acute myelogenous leukemia. Hematol Rep 2012; 4: e18.
    • (2012) Hematol Rep , vol.4
    • Tsuji, K.1    Wang, Y.H.2    Takanashi, M.3    Odajima, T.4    Lee, G.A.5    Sugimori, H.6
  • 7
    • 9144222021 scopus 로고    scopus 로고
    • Death receptor 5 and Bcl-2 protein expression as predictors of tumor response to gemcitabine and cisplatin in patients with advanced non-small-cell lung cancer
    • Han JY, Hong EK, Choi BG, Park JN, Kim KW, Kang JH et al. Death receptor 5 and Bcl-2 protein expression as predictors of tumor response to gemcitabine and cisplatin in patients with advanced non-small-cell lung cancer. Med Oncol 2003; 20: 355-362.
    • (2003) Med Oncol , vol.20 , pp. 355-362
    • Han, J.Y.1    Hong, E.K.2    Choi, B.G.3    Park, J.N.4    Kim, K.W.5    Kang, J.H.6
  • 8
    • 63449133612 scopus 로고    scopus 로고
    • Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma
    • Michaud WA, Nichols AC, Mroz EA, Faquin WC, Clark JR, Begum S et al. Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma. Clin Cancer Res 2009; 15: 1645-1654.
    • (2009) Clin Cancer Res , vol.15 , pp. 1645-1654
    • Michaud, W.A.1    Nichols, A.C.2    Mroz, E.A.3    Faquin, W.C.4    Clark, J.R.5    Begum, S.6
  • 9
    • 12344266609 scopus 로고    scopus 로고
    • Expression of BclxL in ovarian carcinoma is associated with chemoresistance and recurrent disease
    • Williams J, Lucas PC, Griffith KA, Choi M, Fogoros S, Hu YY et al. Expression of BclxL in ovarian carcinoma is associated with chemoresistance and recurrent disease. Gynecol Oncol 2005; 96: 287-295.
    • (2005) Gynecol Oncol , vol.96 , pp. 287-295
    • Williams, J.1    Lucas, P.C.2    Griffith, K.A.3    Choi, M.4    Fogoros, S.5    Hu, Y.Y.6
  • 12
    • 47549105007 scopus 로고    scopus 로고
    • Upregulation of ZNRD1 enhances cisplatin resistance in human esophageal cancer cells by regulation of ERCC1 and Bcl-2
    • Guo W, Zhao YP, Jiang YG, Wang RW, Hong L, Fan DM. Upregulation of ZNRD1 enhances cisplatin resistance in human esophageal cancer cells by regulation of ERCC1 and Bcl-2. Tumour Biol 2008; 29: 188-194.
    • (2008) Tumour Biol , vol.29 , pp. 188-194
    • Guo, W.1    Zhao, Y.P.2    Jiang, Y.G.3    Wang, R.W.4    Hong, L.5    Fan, D.M.6
  • 13
    • 33745392383 scopus 로고    scopus 로고
    • ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2
    • Hong L, Qiao T, Han Y, Han S, Zhang X, Lin T et al. ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2. Biochem Cell Biol 2006; 84: 199-206.
    • (2006) Biochem Cell Biol , vol.84 , pp. 199-206
    • Hong, L.1    Qiao, T.2    Han, Y.3    Han, S.4    Zhang, X.5    Lin, T.6
  • 14
    • 70350400865 scopus 로고    scopus 로고
    • Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library
    • Zhao L, Pan Y, Gang Y, Wang H, Jin H, Tie J et al. Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library. J Biol Chem 2009; 284: 26273-26285.
    • (2009) J Biol Chem , vol.284 , pp. 26273-26285
    • Zhao, L.1    Pan, Y.2    Gang, Y.3    Wang, H.4    Jin, H.5    Tie, J.6
  • 15
    • 2442530500 scopus 로고    scopus 로고
    • Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosis
    • Shi Y, Zhai H, Wang X, Han Z, Liu C, Lan M et al. Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosis. Exp Cell Res 2004; 296: 337-346.
    • (2004) Exp Cell Res , vol.296 , pp. 337-346
    • Shi, Y.1    Zhai, H.2    Wang, X.3    Han, Z.4    Liu, C.5    Lan, M.6
  • 16
    • 27244432205 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Chen C.Z. MicroRNAs as oncogenes and tumor suppressors. N Engl J Med 2005; 353: 1768-1771.
    • (2005) N Engl J Med , vol.353 , pp. 1768-1771
    • Chen, C.Z.1
  • 17
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 19
    • 81255138201 scopus 로고    scopus 로고
    • Reduced miR-128 in breast tumorinitiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5
    • Zhu Y, Yu F, Jiao Y, Feng J, Tang W, Yao H et al. Reduced miR-128 in breast tumorinitiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 2011; 17: 7105-7115.
    • (2011) Clin Cancer Res , vol.17 , pp. 7105-7115
    • Zhu, Y.1    Yu, F.2    Jiao, Y.3    Feng, J.4    Tang, W.5    Yao, H.6
  • 20
    • 84856222156 scopus 로고    scopus 로고
    • MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1
    • Sun L, Yao Y, Liu B, Lin Z, Lin L, Yang M et al. MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. Oncogene 2012; 31: 432-445.
    • (2012) Oncogene , vol.31 , pp. 432-445
    • Sun, L.1    Yao, Y.2    Liu, B.3    Lin, Z.4    Lin, L.5    Yang, M.6
  • 21
    • 79952281614 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
    • Rao X, Di Leva G, Li M, Fang F, Devlin C, Hartman-Frey C et al. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene 2011; 30: 1082-1097.
    • (2011) Oncogene , vol.30 , pp. 1082-1097
    • Rao, X.1    Di Leva, G.2    Li, M.3    Fang, F.4    Devlin, C.5    Hartman-Frey, C.6
  • 22
    • 84863142634 scopus 로고    scopus 로고
    • DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression
    • Ma K, He Y, Zhang H, Fei Q, Niu D, Wang D et al. DNA methylation- regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem 2012; 287: 5639-5649.
    • (2012) J Biol Chem , vol.287 , pp. 5639-5649
    • Ma, K.1    He, Y.2    Zhang, H.3    Fei, Q.4    Niu, D.5    Wang, D.6
  • 23
    • 70450237022 scopus 로고    scopus 로고
    • Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
    • Song B, Wang Y, Xi Y, Kudo K, Bruheim S, Botchkina GI et al. Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene 2009; 28: 4065-4074.
    • (2009) Oncogene , vol.28 , pp. 4065-4074
    • Song, B.1    Wang, Y.2    Xi, Y.3    Kudo, K.4    Bruheim, S.5    Botchkina, G.I.6
  • 24
    • 79955847973 scopus 로고    scopus 로고
    • Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells
    • Zhao X, Yang L, Hu J. Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells. J Exp Clin Cancer Res 2011; 30: 55.
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 55
    • Zhao, X.1    Yang, L.2    Hu, J.3
  • 25
    • 84862888913 scopus 로고    scopus 로고
    • MiR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2
    • Zhu W, Zhu D, Lu S, Wang T, Wang J, Jiang B et al. miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. Med Oncol 2012; 29: 384-391.
    • (2012) Med Oncol , vol.29 , pp. 384-391
    • Zhu, W.1    Zhu, D.2    Lu, S.3    Wang, T.4    Wang, J.5    Jiang, B.6
  • 26
    • 84859779031 scopus 로고    scopus 로고
    • MiR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP
    • Zhu W, Xu H, Zhu D, Zhi H, Wang T, Wang J et al. miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. Cancer Chemother Pharmacol 2012; 69: 723-731.
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 723-731
    • Zhu, W.1    Xu, H.2    Zhu, D.3    Zhi, H.4    Wang, T.5    Wang, J.6
  • 27
    • 77955619456 scopus 로고    scopus 로고
    • MiR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines
    • Zhu W, Shan X, Wang T, Shu Y, Liu P. miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines. Int J Cancer 2010; 127: 2520-2529.
    • (2010) Int J Cancer , vol.127 , pp. 2520-2529
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 28
    • 44949249814 scopus 로고    scopus 로고
    • MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • Zhu W, Shan X, Wang T, Shu Y, Liu P. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 2008; 123: 372-379.
    • (2008) Int J Cancer , vol.123 , pp. 372-379
    • Zhu, W.1    Shan, X.2    Wang, T.3    Shu, Y.4    Liu, P.5
  • 29
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther 2008; 7: 2152-2159.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Chekhun, V.F.6
  • 30
    • 80053257151 scopus 로고    scopus 로고
    • Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia
    • Feng DD, Zhang H, Zhang P, Zheng YS, Zhang XJ, Han BW et al. Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. J Cell Mol Med 2011; 15: 2164-2175.
    • (2011) J Cell Mol Med , vol.15 , pp. 2164-2175
    • Feng, D.D.1    Zhang, H.2    Zhang, P.3    Zheng, Y.S.4    Zhang, X.J.5    Han, B.W.6
  • 31
    • 49149114863 scopus 로고    scopus 로고
    • Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
    • Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG et al. Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 2008; 76: 582-588.
    • (2008) Biochem Pharmacol , vol.76 , pp. 582-588
    • Zhu, H.1    Wu, H.2    Liu, X.3    Evans, B.R.4    Medina, D.J.5    Liu, C.G.6
  • 32
    • 80053257151 scopus 로고    scopus 로고
    • Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukemia
    • Feng DD, Zhang H, Zhang P, Zheng YS, Zhang XJ, Han BW et al. Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukemia. J Cell Mol Med 2011; 15: 2164-2175.
    • (2011) J Cell Mol Med , vol.15 , pp. 2164-2175
    • Feng, D.D.1    Zhang, H.2    Zhang, P.3    Zheng, Y.S.4    Zhang, X.J.5    Han, B.W.6
  • 33
    • 77956183846 scopus 로고    scopus 로고
    • Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma
    • Zhang H, Li M, Han Y, Hong L, Gong T, Sun L et al. Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma. Dig Dis Sci 2010; 55: 2545-2551.
    • (2010) Dig Dis Sci , vol.55 , pp. 2545-2551
    • Zhang, H.1    Li, M.2    Han, Y.3    Hong, L.4    Gong, T.5    Sun, L.6
  • 34
    • 82255185758 scopus 로고    scopus 로고
    • Tunicamycin depresses p-glycoprotein glycosylation without an effect on its membrane localization and drug efflux activity in l1210 cells
    • Seres M, Cholujova D, Bubenckova T, Breier A, Sulova Z. Tunicamycin depresses p-glycoprotein glycosylation without an effect on its membrane localization and drug efflux activity in l1210 cells. Int J Mol Sci 2011; 12: 7772-7784.
    • (2011) Int J Mol Sci , vol.12 , pp. 7772-7784
    • Seres, M.1    Cholujova, D.2    Bubenckova, T.3    Breier, A.4    Sulova, Z.5
  • 35
    • 0034142125 scopus 로고    scopus 로고
    • Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system
    • Gribar JJ, Ramachandra M, Hrycyna CA, Dey S, Ambudkar SV. Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system. J Mem Biol 2000; 173: 203-214.
    • (2000) J Mem Biol , vol.173 , pp. 203-214
    • Gribar, J.J.1    Ramachandra, M.2    Hrycyna, C.A.3    Dey, S.4    Ambudkar, S.V.5
  • 36
    • 0028901907 scopus 로고
    • Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype
    • Kramer R, Weber TK, Arceci R, Ramchurren N, Kastrinakis WV, Steele Jr G et al. Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype. Br J Cancer 1995; 71: 670-675.
    • (1995) Br J Cancer , vol.71 , pp. 670-675
    • Kramer, R.1    Weber, T.K.2    Arceci, R.3    Ramchurren, N.4    Kastrinakis, W.V.5    Steele Jr., G.6
  • 37
    • 11244301795 scopus 로고    scopus 로고
    • Reversal of multidrug resistance of gastric cancer cells by down-regulation of ZNRD1 with ZNRD1 siRNA
    • Hong L, Ning X, Shi Y, Shen H, Zhang Y, Lan M et al. Reversal of multidrug resistance of gastric cancer cells by down-regulation of ZNRD1 with ZNRD1 siRNA. Br J Biomed Sci 2004; 61: 206-210.
    • (2004) Br J Biomed Sci , vol.61 , pp. 206-210
    • Hong, L.1    Ning, X.2    Shi, Y.3    Shen, H.4    Zhang, Y.5    Lan, M.6
  • 38
    • 4344572739 scopus 로고    scopus 로고
    • Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein
    • Hong L, Ning X, Shi Y, Shen H, Zhang Y, Lan M et al. Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein. Cancer Biol Ther 2004; 3: 377-381.
    • (2004) Cancer Biol Ther , vol.3 , pp. 377-381
    • Hong, L.1    Ning, X.2    Shi, Y.3    Shen, H.4    Zhang, Y.5    Lan, M.6
  • 39
    • 77956296766 scopus 로고    scopus 로고
    • Identification of microRNA-21as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer
    • Hwang JH, Voortman J, Giovannetti E, Steinberg SM, Leon LG, Kim YT et al. Identification of microRNA-21as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer. PLoS One 2010; 5: e10630.
    • (2010) PLoS One , vol.5
    • Hwang, J.H.1    Voortman, J.2    Giovannetti, E.3    Steinberg, S.M.4    Leon, L.G.5    Kim, Y.T.6
  • 40
    • 84867397137 scopus 로고    scopus 로고
    • MicroRNA-10b is a prognostic indicator in colorectal cancer and confers resistance to the chemotherapeutic agent 5-fluorouracil in colorectal cancer cells
    • Nishida N, Yamashita S, Mimori K, Sudo T, Tanaka F, Shibata K et al. MicroRNA-10b is a prognostic indicator in colorectal cancer and confers resistance to the chemotherapeutic agent 5-fluorouracil in colorectal cancer cells. Ann Surg Oncol 2012; 19: 3065-3071.
    • (2012) Ann Surg Oncol , vol.19 , pp. 3065-3071
    • Nishida, N.1    Yamashita, S.2    Mimori, K.3    Sudo, T.4    Tanaka, F.5    Shibata, K.6
  • 41
    • 67549139894 scopus 로고    scopus 로고
    • Tumor micro RNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients
    • Eitan R, Kushnir M, Lithwick-Yanai G, David MB, Hoshen M, Glezerman M et al. Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients. Gynecol Oncol 2009; 114: 253-259.
    • (2009) Gynecol Oncol , vol.114 , pp. 253-259
    • Eitan, R.1    Kushnir, M.2    Lithwick-Yanai, G.3    David, M.B.4    Hoshen, M.5    Glezerman, M.6
  • 42
    • 81555234231 scopus 로고    scopus 로고
    • MiRNA signature associated with outcome of gastric cancer patients following chemotherapy
    • Kim CH, Kim HK, Rettig RL, Kim J, Lee ET, Aprelikova O et al. miRNA signature associated with outcome of gastric cancer patients following chemotherapy. BMC Med Genomics 2011; 4: 79.
    • (2011) BMC Med Genomics , vol.4 , pp. 79
    • Kim, C.H.1    Kim, H.K.2    Rettig, R.L.3    Kim, J.4    Lee, E.T.5    Aprelikova, O.6
  • 43
    • 84866423871 scopus 로고    scopus 로고
    • Micro RNAs in the p53 network: Micromanagement of tumour suppression
    • Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 2012; 12: 613-626.
    • (2012) Nat Rev Cancer , vol.12 , pp. 613-626
    • Hermeking, H.1
  • 44
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • Hou J, Lin L, Zhou W, Wang Z, Ding G, Dong Q et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 2011; 19: 232-243.
    • (2011) Cancer Cell , vol.19 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3    Wang, Z.4    Ding, G.5    Dong, Q.6
  • 45
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific micro RNAs regulate the G1-S transition and promote rapid proliferation
    • Wang Y, Baskerville S, Shenoy A, Babiarz JE, Baehner L, Blelloch R. Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet 2008; 40: 1478-1483.
    • (2008) Nat Genet , vol.40 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.E.4    Baehner, L.5    Blelloch, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.