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Volumn 12, Issue 11, 2011, Pages 7772-7784

Tunicamycin depresses P-glycoprotein glycosylation without an effect on its membrane localization and drug efflux activity in L1210 cells

Author keywords

L1210; N glycosylation; P gp (MDR1); Tunicamycin

Indexed keywords

GLYCOPROTEIN P; TUNICAMYCIN; VINCRISTINE; ABCB1 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN;

EID: 82255185758     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12117772     Document Type: Article
Times cited : (35)

References (31)
  • 1
    • 23844521998 scopus 로고    scopus 로고
    • P-glycoprotein-implications of metabolism of neoplastic cells and cancer therapy
    • Breier, A.; Barancik, M.; Sulova, Z.; Uhrik, B. P-glycoprotein-implications of metabolism of neoplastic cells and cancer therapy. Curr. Cancer Drug Targets 2005, 5, 457-468.
    • (2005) Curr. Cancer Drug Targets , vol.5 , pp. 457-468
    • Breier, A.1    Barancik, M.2    Sulova, Z.3    Uhrik, B.4
  • 2
    • 73949102380 scopus 로고    scopus 로고
    • Multidrug resistance in cancer
    • Baguley, B.C. Multidrug resistance in cancer. Methods Mol. Biol. 2010, 596, 1-14.
    • (2010) Methods Mol. Biol , vol.596 , pp. 1-14
    • Baguley, B.C.1
  • 3
    • 0034042332 scopus 로고    scopus 로고
    • Cytotoxic activity of several unrelated drugs on L1210 mouse leukemic cell sublines with P-glycoprotein (PGP) mediated multidrug resistance (MDR) phenotype
    • Breier, A.; Drobna, Z.; Docolomansky, P.; Barancik, M. Cytotoxic activity of several unrelated drugs on L1210 mouse leukemic cell sublines with P-glycoprotein (PGP) mediated multidrug resistance (MDR) phenotype. A QSAR study. Neoplasma 2000, 47, 100-106.
    • (2000) A QSAR Study. Neoplasma , vol.47 , pp. 100-106
    • Breier, A.1    Drobna, Z.2    Docolomansky, P.3    Barancik, M.4
  • 4
    • 34547852327 scopus 로고    scopus 로고
    • Distinct N-glycan glycosylation of P-glycoprotein isolated from the human uterine sarcoma cell line MES-SA/Dx5
    • Greer, D.A.; Ivey, S. Distinct N-glycan glycosylation of P-glycoprotein isolated from the human uterine sarcoma cell line MES-SA/Dx5. Biochim. Biophys. Acta 2007, 1770, 1275-1282.
    • (2007) Biochim. Biophys. Acta , vol.1770 , pp. 1275-1282
    • Greer, D.A.1    Ivey, S.2
  • 5
    • 7644238103 scopus 로고    scopus 로고
    • Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein
    • Loo, T.W.; Bartlett, M.C.; Clarke, D.M. Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein. Biochem. Biophys. Res. Commun. 2004, 325, 580-585.
    • (2004) Biochem. Biophys. Res. Commun , vol.325 , pp. 580-585
    • Loo, T.W.1    Bartlett, M.C.2    Clarke, D.M.3
  • 6
    • 0027408359 scopus 로고
    • N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein
    • Schinkel, A.H.; Kemp, S.; Dolle, M.; Rudenko, G.; Wagenaar, E. N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein. J. Biol. Chem. 1993, 268, 7474-7481.
    • (1993) J. Biol. Chem , vol.268 , pp. 7474-7481
    • Schinkel, A.H.1    Kemp, S.2    Dolle, M.3    Rudenko, G.4    Wagenaar, E.5
  • 7
    • 0032483985 scopus 로고    scopus 로고
    • Quality control by proteases in the endoplasmic reticulum. Removal of a protease-sensitive site enhances expression of human P-glycoprotein
    • Loo, T.W.; Clarke, D.M. Quality control by proteases in the endoplasmic reticulum. Removal of a protease-sensitive site enhances expression of human P-glycoprotein. J. Biol. Chem. 1998, 273, 32373-32376.
    • (1998) J. Biol. Chem , vol.273 , pp. 32373-32376
    • Loo, T.W.1    Clarke, D.M.2
  • 8
    • 68349133246 scopus 로고    scopus 로고
    • Structure, expression, and regulation of UDP-GlcNAc: Dolichol phosphate GlcNAc-1-phosphate transferase (DPAGT1)
    • Bretthauer, R.K. Structure, expression, and regulation of UDP-GlcNAc: dolichol phosphate GlcNAc-1-phosphate transferase (DPAGT1). Curr. Drug Targets 2009, 10, 477-482.
    • (2009) Curr. Drug Targets , vol.10 , pp. 477-482
    • Bretthauer, R.K.1
  • 9
    • 0242610852 scopus 로고    scopus 로고
    • Glucose depletion enhances P-glycoprotein expression in hepatoma cells: Role of endoplasmic reticulum stress response
    • Ledoux, S.; Yang, R.; Friedlander, G.; Laouari, D. Glucose depletion enhances P-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Res. 2003, 63, 7284-7290.
    • (2003) Cancer Res , vol.63 , pp. 7284-7290
    • Ledoux, S.1    Yang, R.2    Friedlander, G.3    Laouari, D.4
  • 10
    • 77951230294 scopus 로고    scopus 로고
    • Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: A mechanistic study employing molecular genomics
    • Gaddameedhi, S.; Chatterjee, S. Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics. J. Cancer Res. Ther. 2009, 5, S61-S66.
    • (2009) J. Cancer Res. Ther , vol.5
    • Gaddameedhi, S.1    Chatterjee, S.2
  • 11
    • 42949147649 scopus 로고    scopus 로고
    • A23187, ionomycin and thapsigargin upregulate mRNA of HIF-1alpha via endoplasmic reticulum stress rather than a rise in intracellular calcium
    • Werno, C.; Zhou, J.; Brune, B. A23187, ionomycin and thapsigargin upregulate mRNA of HIF-1alpha via endoplasmic reticulum stress rather than a rise in intracellular calcium. J. Cell Physiol. 2008, 215, 708-714.
    • (2008) J. Cell Physiol , vol.215 , pp. 708-714
    • Werno, C.1    Zhou, J.2    Brune, B.3
  • 12
    • 34547487284 scopus 로고    scopus 로고
    • Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells
    • Hiss, D.C.; Gabriels, G.A.; Folb, P.I. Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells. Cancer Cell Int. 2007, 7, 5.
    • (2007) Cancer Cell Int , vol.7 , pp. 5
    • Hiss, D.C.1    Gabriels, G.A.2    Folb, P.I.3
  • 13
    • 4944242078 scopus 로고    scopus 로고
    • Regulation of the stability of P-glycoprotein by ubiquitination
    • Zhang, Z.; Wu, J.Y.; Hait, W.N.; Yang, J.M. Regulation of the stability of P-glycoprotein by ubiquitination. Mol. Pharmacol. 2004, 66, 395-403.
    • (2004) Mol. Pharmacol , vol.66 , pp. 395-403
    • Zhang, Z.1    Wu, J.Y.2    Hait, W.N.3    Yang, J.M.4
  • 14
    • 0026695622 scopus 로고
    • Adaptation of mouse leukemia cells L1210 to vincristine. Evidence for expression of P-glycoprotein
    • Polekova, L.; Barancik, M.; Mrazova, T.; Pirker, R.; Wallner, J.; Sulova, Z.; Breier, A. Adaptation of mouse leukemia cells L1210 to vincristine. Evidence for expression of P-glycoprotein. Neoplasma 1992, 39, 73-77.
    • (1992) Neoplasma , vol.39 , pp. 73-77
    • Polekova, L.1    Barancik, M.2    Mrazova, T.3    Pirker, R.4    Wallner, J.5    Sulova, Z.6    Breier, A.7
  • 18
    • 0020623816 scopus 로고
    • Changes in cell surface glycoproteins on non-differentiating L6 rat myoblasts selected for resistance to concanavalin A
    • Parfett, C.L.; Jamieson, J.C.; Wright, J.A. Changes in cell surface glycoproteins on non-differentiating L6 rat myoblasts selected for resistance to concanavalin A. Exp. Cell Res. 1983, 144, 405-415.
    • (1983) Exp. Cell Res , vol.144 , pp. 405-415
    • Parfett, C.L.1    Jamieson, J.C.2    Wright, J.A.3
  • 19
    • 0033669380 scopus 로고    scopus 로고
    • Evaluation of a vincristine resistant Caco-2 cell line for use in a calcein AM extrusion screening assay for P-glycoprotein interaction
    • Eneroth, A.; Astrom, E.; Hoogstraate, J.; Schrenk, D.; Conrad, S.; Kauffmann, H.M.; Gjellan, K. Evaluation of a vincristine resistant Caco-2 cell line for use in a calcein AM extrusion screening assay for P-glycoprotein interaction. Eur. J. Pharm. Sci. 2001, 12, 205-214.
    • (2001) Eur. J. Pharm. Sci , vol.12 , pp. 205-214
    • Eneroth, A.1    Astrom, E.2    Hoogstraate, J.3    Schrenk, D.4    Conrad, S.5    Kauffmann, H.M.6    Gjellan, K.7
  • 21
    • 5744228959 scopus 로고    scopus 로고
    • Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome
    • Ross, D.D. Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome. Best Pract. Res. Clin. Haematol. 2004, 17, 641-651.
    • (2004) Best Pract. Res. Clin. Haematol , vol.17 , pp. 641-651
    • Ross, D.D.1
  • 22
    • 0020684716 scopus 로고
    • The biochemical and ultrastructural effects of tunicamycin and D-glucosamine in L1210 leukemic cells
    • Morin, M.J.; Porter, C.W.; McKernan, P.; Bernacki, R.J. The biochemical and ultrastructural effects of tunicamycin and D-glucosamine in L1210 leukemic cells. J. Cell Physiol. 1983, 114, 162-172.
    • (1983) J. Cell Physiol , vol.114 , pp. 162-172
    • Morin, M.J.1    Porter, C.W.2    McKernan, P.3    Bernacki, R.J.4
  • 23
    • 78650631011 scopus 로고    scopus 로고
    • Effect of thapsigargin on P-glycoprotein-negative and P-glycoprotein-positive L1210 mouse leukaemia cells
    • Seres, M.; Ditte, P.; Breier, A.; Sulova, Z. Effect of thapsigargin on P-glycoprotein-negative and P-glycoprotein-positive L1210 mouse leukaemia cells. Gen. Physiol. Biophys. 2010, 29, 396-401.
    • (2010) Gen. Physiol. Biophys , vol.29 , pp. 396-401
    • Seres, M.1    Ditte, P.2    Breier, A.3    Sulova, Z.4
  • 24
    • 0028901907 scopus 로고
    • Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype
    • Kramer, R.; Weber, T.K.; Arceci, R.; Ramchurren, N.; Kastrinakis, W.V.; Steele, G., Jr.; Summerhayes, I.C. Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype. Br. J. Cancer 1995, 71, 670-675.
    • (1995) Br. J. Cancer , vol.71 , pp. 670-675
    • Kramer, R.1    Weber, T.K.2    Arceci, R.3    Ramchurren, N.4    Kastrinakis, W.V.5    Steele Jr., G.6    Summerhayes, I.C.7
  • 25
    • 0030898656 scopus 로고    scopus 로고
    • The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation
    • Bentley, J.; Quinn, D.M.; Pitman, R.S.; Warr, J.R.; Kellett, G.L. The human KB multidrug-resistant cell line KB-C1 is hypersensitive to inhibitors of glycosylation. Cancer Lett. 1997, 115, 221-227.
    • (1997) Cancer Lett , vol.115 , pp. 221-227
    • Bentley, J.1    Quinn, D.M.2    Pitman, R.S.3    Warr, J.R.4    Kellett, G.L.5
  • 27
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan, I.; Gottesman, M.M.; Ueda, K.; Lovelace, E.; Rutherford, A.V.; Willingham, M.C. A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc. Natl. Acad. Sci. USA 1988, 85, 4486-4490.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutherford, A.V.5    Willingham, M.C.6
  • 28
    • 0023019005 scopus 로고
    • Use of MTT colorimetric assay to measure cell activation
    • Gerlier, D.; Thomasset, N. Use of MTT colorimetric assay to measure cell activation. J. Immunol. Methods 1986, 94, 57-63.
    • (1986) J. Immunol. Methods , vol.94 , pp. 57-63
    • Gerlier, D.1    Thomasset, N.2
  • 29
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H.; Staehelin, T.; Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 1979, 76, 4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 31
    • 22944477782 scopus 로고    scopus 로고
    • DAPI fluorescence in nuclei isolated from tumors
    • Krishan, A.; Dandekar, P.D. DAPI fluorescence in nuclei isolated from tumors. J. Histochem. Cytochem. 2005, 53, 1033-1036.
    • (2005) J. Histochem. Cytochem , vol.53 , pp. 1033-1036
    • Krishan, A.1    Dandekar, P.D.2


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