Sex, drugs, and violence: Neuromodulation of attachment and conflict in voles

Current Topics in Behavioral Neurosciences

Volumn 17, Issue , 2014, Pages 229-264

  Gobrogge, Kyle L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Addiction; Anterior hypothalamus; Dopamine; Drug abuse; Mating; Medial amygdala; Neural circuitry; Nucleus accumbens; Oxytocin; Social attachment; Vasopressin; Ventral tegmental area

Indexed keywords

ADENYLATE CYCLASE; DOPAMINE; NEUROTRANSMITTER; OXYTOCIN; VASOPRESSIN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS;

ANIMAL MODEL; ARTICLE; DRUG ABUSE; ELECTROSTIMULATION; FEMALE; HUMAN; IMMUNOREACTIVITY; MALE; MATING; MICROPHOTOGRAPHY; NERVOUS SYSTEM; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RODENT MODEL; SEX; SOCIAL BONDING; VIOLENCE; ANIMAL; ARVICOLINAE; CONFLICT; METABOLISM; OBJECT RELATION; PAIR BONDING; PHYSIOLOGY; REVIEW;

ANIMALS; ARVICOLINAE; CONFLICT (PSYCHOLOGY); FEMALE; HUMANS; MALE; NEUROTRANSMITTER AGENTS; OBJECT ATTACHMENT; PAIR BOND;

EID: 84908021126     PISSN: 18663370     EISSN: 18663389     Source Type: Book Series    
DOI: 10.1007/7854_2013_264     Document Type: Article

References (248)

1. Adams DB, Boudreau W, Cowan CW, Kokonowski C, Oberteuffer K, Yohay K (1993) Offense produced by chemical stimulation of the anterior hypothalamus of the rat. Physiol Behav 53: 1127-1132.
2. Albers EH, Dean A, Karom MC, Smith D, Huhman KL (2006) Role of V1a vasopressin receptors in the control of aggression in Syrian hamsters. Brain Res 1073-1074: 425-430.
3. Albert DJ, Walsh ML (1984) Neural systems and the inhibitory modulation of agonistic behavior: a comparison of mammalian species. Neurosci Biobehav Rev 8: 5-24.
4. Alcaro A, Huber R, Panksepp J (2007) Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev 56: 283-321.
5. Aragona BJ, Detwiler JM, Wang Z (2007) Amphetamine reward in the monogamous prairie vole. Neurosci Lett 418: 190-194.
6. Aragona BJ, Liu Y, Curtis JT, Stephan FK, Wang Z (2003) A critical role for nucleus accumbens dopamine in partner-preference formation in male prairie voles. J Neurosci 23: 3483-3490.
7. Aragona BJ, Liu Y, Yu YJ, Curtis JT, Detwiler JM, Insel TR, Wang Z (2006) Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nat Neurosci 9: 133-139.
8. Aragona BJ, Wang Z (2007) Opposing regulation of pair bond formation by cAMP signaling within the nucleus accumbens shell. J Neurosci 27: 13352-13356.
9. Aragona BJ, Wang Z (2009) Dopamine regulation of social choice in a monogamous rodent species. Front Behav Neurosci 3: 15.
10. Asmus SE, Kincaid AE, Newman SW (1992) A species-specific population of tyrosine hydroxylase-immunoreactive neurons in the medial amygdaloid nucleus of the Syrian hamster. Brain Res 575: 199-207.
11. Asmus SE, Newman SW (1993) Tyrosine hydroxylase neurons in the male hamster chemosensory pathway contain androgen receptors and are influenced by gonadal hormones. J Comp Neurol 331: 445-457.
12. Backstrom T, Winberg S (2009) Arginine-vasotocin influence on aggressive behavior and dominance in rainbow trout. Physiol Behav 96: 470-475.
13. Baler RD, Volkow ND (2006) Drug addiction: the neurobiology of disrupted self-control. Trends Mol Med 12: 559-566.
14. Bales KL, Carter CS (2003) Sex differences and developmental effects of oxytocin on aggression and social behavior in prairie voles (Microtus ochrogaster). Horm Behav 44: 178-184.
15. Bamshad M, Novak MA, De Vries GJ (1993) Sex and species differences in the vasopressin innervation of sexually naive and parental prairie voles, Microtus ochrogaster and meadow voles, Microtus pennsylvanicus. J Neuroendocrinol 5: 247-255.
16. Bartels A, Zeki S (2004) The neural correlates of maternal and romantic love. Neuroimage 21: 1155-1166.
17. Bermond B, Mos J, Meelis W, van der Poel AM, Kruk MR (1982) Aggression induced by stimulation of the hypothalamus: effects of androgens. Pharmacol Biochem Behav 16: 41-45.
18. Bielsky IF, Hu SB, Ren X, Terwilliger EF, Young LJ (2005) The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement study. Neuron 47: 503-513.
19. Bosch OJ, Nair HP, Ahern TH, Neumann ID, Young LJ (2009) The CRF system mediates increased passive stress-coping behavior following the loss of a bonded partner in a monogamous rodent. Neuropsychopharmacology 34: 1406-1415.
20. Bowler CM, Cushing BS, Carter CS (2002) Social factors regulate female-female aggression and affiliation in prairie voles. Physiol Behav 76: 559-566.
21. Boyson SJ, McGonigle P, Molinoff PB (1986) Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain. J Neurosci 6: 3177-3188.
22. Brackett NL, Iuvone PM, Edwards DA (1986) Midbrain lesions, dopamine and male sexual behavior. Behav Brain Res 20: 231-240.
23. Caldwell HK, Albers HE (2004) Effect of photoperiod on vasopressin-induced aggression in Syrian hamsters. Horm Behav 46: 444-449.
24. Caldwell HK, Lee HJ, Macbeth AH, Young WS III (2008) Vasopressin: behavioral roles of an "original" neuropeptide. Prog Neurobiol 84: 1-24.
25. Callier S, Snapyan M, Le Crom S, Prou D, Vincent JD, Vernier P (2003) Evolution and cell biology of dopamine receptors in vertebrates. Biol Cell 95: 489-502.
26. Calon F, Hadj Tahar A, Blanchet PJ, Morissette M, Grondin R, Goulet M, Doucet JP, Robertson GS, Nestler E, Di Paolo T, Bedard PJ (2000) Dopamine-receptor stimulation: biobehavioral and biochemical consequences. Trends Neurosci 23: S92-100.
27. Carr DB, Sesack SR (2000) Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons. J Neurosci 20: 3864-3873.
28. Carter CS, De Vries AC, Getz LL (1995) Physiological substrates of mammalian monogamy: the prairie vole model. Neurosci Biobehav Rev 19: 303-314.
29. Carter CS, Getz LL (1993) Monogamy and the prairie vole. Sci Am 268: 100-106.
30. Cavanaugh BL, Lonstein JS (2010) Social novelty increases tyrosine hydroxylase immunoreactivity in the extended olfactory amygdala of female prairie voles. Physiol Behav 100: 381-386.
31. Chassler L (1997) Understanding anorexia nervosa and bulimia nervosa from an attachment perspective. Clin Soc Work J 25: 407-423.
32. Chermack ST, Murray RL, Walton MA, Booth BA, Wryobeck J, Blow FC (2008) Partner aggression among men and women in substance use disorder treatment: correlates of psychological and physical aggression and injury. Drug Alcohol Depend 98: 35-44.
33. Cheung S, Ballew JR, Moore KE, Lookingland KJ (1998) Contribution of dopamine neurons in the medial zona incerta to the innervation of the central nucleus of the amygdala, horizontal diagonal band of Broca and hypothalamic paraventricular nucleus. Brain Res 808: 174-181.
34. Choi GB, Dong HW, Murphy AJ, Valenzuela DM, Yancopoulos GD, Swanson LW, Anderson DJ (2005) Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus. Neuron 46: 647-660.
35. Clifton PG, Somerville EM (1994) Disturbance of meal patterning following nucleus accumbens lesions in the rat. Brain Res 667: 123-128.
36. Coccaro EF, Kavoussi RJ, Hauger RL, Cooper TB, Ferris CF (1998) Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects. Arch Gen Psychiatry 55: 708-714.
37. Cooper MA, Karom M, Huhman KL, Albers HE (2005) Repeated agonistic encounters in hamsters modulate AVP V1a receptor binding. Horm Behav 48: 545-551.
38. Curtis JT, Hood AN, Chen Y, Cobb GP, Wallace DR (2010) Chronic metals ingestion by prairie voles produces sex-specific deficits in social behavior: an animal model of autism. Behav Brain Res 213: 42-49.
39. Curtis JT, Stowe JR, Wang Z (2003) Differential effects of intraspecific interactions on the striatal dopamine system in social and non-social voles. Neuroscience 118: 1165-1173.
40. Curtis JT, Wang Z (2003) Forebrain c-fos expression under conditions conducive to pair bonding in female prairie voles (Microtus ochrogaster). Physiol Behav 80: 95-101.
41. Curtis JT, Wang Z (2005a) Glucocorticoid receptor involvement in pair bonding in female prairie voles: the effects of acute blockade and interactions with central dopamine reward systems. Neuroscience 134: 369-376.
42. Curtis JT, Wang Z (2005b) Ventral tegmental area involvement in pair bonding in male prairie voles. Physiol Behav 86: 338-346.
43. Cushing BS, Mogekwu N, Le WW, Hoffman GE, Carter CS (2003a) Cohabitation induced Fos immunoreactivity in the monogamous prairie vole. Brain Res 965: 203-211.
44. Cushing BS, Yamamoto Y, Hoffman GE, Carter CS (2003b) Central expression of c-Fos in neonatal male and female prairie voles in response to treatment with oxytocin. Brain Res Dev Brain Res 143: 129-136.
45. De Leon KR, Grimes JM, Connor DF, Melloni RH Jr (2002a) Adolescent cocaine exposure and offensive aggression: involvement of serotonin neural signaling and innervation in male Syrian hamsters. Behav Brain Res 133: 211-220.
46. De Leon KR, Grimes JM, Melloni RH Jr (2002b) Repeated anabolic-androgenic steroid treatment during adolescence increases vasopressin V(1A) receptor binding in Syrian hamsters: correlation with offensive aggression. Horm Behav 42: 182-191.
47. Delville Y, De Vries GJ, Ferris CF (2000) Neural connections of the anterior hypothalamus and agonistic behavior in golden hamsters. Brain Behav Evol 55: 53-76.
48. Demas GE, Moffatt CA, Drazen DL, Nelson RJ (1999) Castration does not inhibit aggressive behavior in adult male prairie voles (Microtus ochrogaster). Physiol Behav 66: 59-62.
49. De Vries AC, DeVries MB, Taymans S, Carter CS (1995) Modulation of pair bonding in female prairie voles (Microtus ochrogaster) by corticosterone. Proc Natl Acad Sci U S A 92: 7744-7748.
50. Dewsbury DA (1987) The comparative psychology of monogamy. Nebr Symp Motiv 35: 1-50.
51. Deyo RA, Straube KT, Disterhoft JF (1989) Nimodipine facilitates associative learning in aging rabbits. Science 243: 809-811.
52. Dominguez JM, Gil M, Hull EM (2006) Preoptic glutamate facilitates male sexual behavior. J Neurosci 26: 1699-1703.
53. Donaldson ZR, Young LJ (2008) Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322: 900-904.
54. Duncan GJ, Wilkerson B, England P (2003) Cleaning up their act: the impact of marriage and cohabitation on licit and illicit drug use. Northwestern University, WP.
55. El-Bassel N, Witte SS, Wada T, Gilbert L, Wallace J (2001) Correlates of partner violence among female street-based sex workers: substance abuse, history of childhood abuse, and HIV risks. AIDS Patient Care STDS 15: 41-51.
56. Ericsson M, Poston WS II, Foreyt JP (1996) Common biological pathways in eating disorders and obesity. Addict Behav 21: 733-743.
57. Eyny YS, Horvitz JC (2003) Opposing roles of D1 and D2 receptors in appetitive conditioning. J Neurosci 23: 1584-1587.
58. Farooque RS, Stout RG, Ernst FA (2005) Heterosexual intimate partner homicide: review of ten years of clinical experience. J Forensic Sci 50: 648-651.
59. Ferris CF, Albers HE, Wesolowski SM, Goldman BD, Luman SE (1984) Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters. Science 224: 521-523.
60. Ferris CF, Axelson JF, Martin AM, Roberge LF (1989) Vasopressin immunoreactivity in the anterior hypothalamus is altered during the establishment of dominant/subordinate relationships between hamsters. Neuroscience 29: 675-683.
61. Ferris CF, Lu SF, Messenger T, Guillon CD, Heindel N, Miller M, Koppel G, Robert Bruns F, Simon NG (2006) Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior. Pharmacol Biochem Behav 83: 169-174.
62. Ferris CF, Melloni RH Jr, Koppel G, Perry KW, Fuller RW, Delville Y (1997) Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters. J Neurosci 17: 4331-4340.
63. Ferris CF, Potegal M (1988) Vasopressin receptor blockade in the anterior hypothalamus suppresses aggression in hamsters. Physiol Behav 44: 235-239.
64. Fisher H, Aron A, Brown LL (2005) Romantic love: an fMRI study of a neural mechanism for mate choice. J Comp Neurol 493: 58-62.
65. Gatewood JD, Wills A, Shetty S, Xu J, Arnold AP, Burgoyne PS, Rissman EF (2006) Sex chromosome complement and gonadal sex influence aggressive and parental behaviors in mice. J Neurosci 26: 2335-2342.
66. Getz LL, Carter CS, Gavish L (1981) The mating system of the prairie vole, Microtus ochrogaster. Field and laboratory evidence for pair-bonding. Beh Ecol Sociobio 8: 189-194.
67. Getz LL, Hofmann JE (1986) Social organization in free-living prairie voles, Microtus ochrogaster. Beh Ecol Sociobio 18: 275-282.
68. Gingrich B, Liu Y, Cascio C, Wang Z, Insel TR (2000) Dopamine D2 receptors in the nucleus accumbens are important for social attachment in female prairie voles (Microtus ochrogaster). Behav Neurosci 114: 173-183.
69. Gingrich BS, Huot RL, Wang Z, Insel TR (1997) Differential Fos expression following microinjection of oxytocin or vasopressin in the prairie vole brain. Ann N Y Acad Sci 807: 504-505.
70. Gobrogge KL, Liu Y, Jia X, Wang Z (2007) Anterior hypothalamic neural activation and neurochemical associations with aggression in pair-bonded male prairie voles. J Comp Neurol 502: 1109-1122.
71. Gobrogge KL, Liu Y, Wang Z (2008) Dopamine regulation of pair bonding in monogamous prairie voles. In: Bridges R (ed) The neurobiology of the parental brain. Elsevier, San Diego, pp 345-358.
72. Gobrogge KL, Liu Y, Young LJ, Wang Z (2009) Anterior hypothalamic vasopressin regulates pair-bonding and drug-induced aggression in a monogamous rodent. Proc Natl Acad Sci U S A 106: 19144-19149.
73. Gobrogge KL, Wang Z (2009) Neural circuitry underlying pair bonding-induced aggression in monogamous male prairie voles. In: Society for Neuroscience Abstracts #3774 Chicago, IL.
74. Gobrogge KL, Wang Z (2011) Genetics of aggression in voles. Adv Genet 75: 121-150.
75. Gonzaga GC, Turner RA, Keltner D, Campos B, Altemus M (2006) Romantic love and sexual desire in close relationships. Emotion 6: 163-179.
76. Goodson JL (2008) Nonapeptides and the evolutionary patterning of sociality. Prog Brain Res 170: 3-15.
77. Grimes JM, Ricci LA, Melloni RH Jr (2007) Alterations in anterior hypothalamic vasopressin, but not serotonin, correlate with the temporal onset of aggressive behavior during adolescent anabolic-androgenic steroid exposure in hamsters (Mesocricetus auratus). Behav Neurosci 121: 941-948.
78. Grippo AJ, Cushing BS, Carter CS (2007) Depression-like behavior and stressor-induced neuroendocrine activation in female prairie voles exposed to chronic social isolation. Psychosom Med 69: 149-157.
79. Haapasalo J, Hamalainen T (1996) Childhood family problems and current psychiatric problems among young violent and property offenders. J Am Acad Child Adolesc Psychiatry 35: 1394-1401.
80. Hagelstam C, Hakkanen H (2006) Adolescent homicides in Finland: offence and offender characteristics. Forensic Sci Int 164: 110-115.
81. Hairston JE, Ball GF, Nelson RJ (2003) Photoperiodic and temporal influences on chemosensory induction of brain fos expression in female prairie voles. J Neuroendocrinol 15: 161-172.
82. Haller J, Abraham I, Zelena D, Juhasz G, Makara GB, Kruk MR (1998) Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area. Behav Pharmacol 9: 469-475.
83. Hammock EA, Young LJ (2002) Variation in the vasopressin V1a receptor promoter and expression: implications for inter-and intraspecific variation in social behaviour. Eur J Neurosci 16: 399-402.
84. Hammock EA, Young LJ (2004) Functional microsatellite polymorphism associated with divergent social structure in vole species. Mol Biol Evol 21: 1057-1063.
85. Hammock EA, Young LJ (2005) Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 308: 1630-1634.
86. Harrison RJ, Connor DF, Nowak C, Melloni RH Jr (2000a) Chronic low-dose cocaine treatment during adolescence facilitates aggression in hamsters. Physiol Behav 69: 555-562.
87. Harrison RJ, Connor DF, Nowak C, Nash K, Melloni RH Jr (2000b) Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters. Psychoneuroendocrinology 25: 317-338.
88. Havassy BE, Wasserman DA, Hall SM (1995) Social relationships and abstinence from cocaine in an American treatment sample. Addiction 90: 699-710.
89. Hernandez L, Hoebel BG (1989) Food intake and lateral hypothalamic self-stimulation covary after medial hypothalamic lesions or ventral midbrain 6-hydroxydopamine injections that cause obesity. Behav Neurosci 103: 412-422.
90. Hostetler CM, Harkey SL, Bales KL (2010) D2 antagonist during development decreases anxiety and infanticidal behavior in adult female prairie voles (Microtus ochrogaster). Behav Brain Res 210: 127-130.
91. Hull EM, Dominguez JM (2006) Getting his act together: roles of glutamate, nitric oxide, and dopamine in the medial preoptic area. Brain Res 1126: 66-75.
92. Hull EM, Dominguez JM (2007) Sexual behavior in male rodents. Horm Behav 52: 45-55.
93. Hull EM, Eaton RC, Moses J, Lorrain D (1993) Copulation increases dopamine activity in the medial preoptic area of male rats. Life Sci 52: 935-940.
94. Hull EM, Muschamp JW, Sato S (2004) Dopamine and serotonin: influences on male sexual behavior. Physiol Behav 83: 291-307.
95. Ikemoto S, Panksepp J (1999) The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev 31: 6-41.
96. Insel TR (2003) Is social attachment an addictive disorder? Physiol Behav 79: 351-357.
97. Insel TR (2010) The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior. Neuron 65: 768-779.
98. Insel TR, Hulihan TJ (1995) A gender-specific mechanism for pair bonding: oxytocin and partner preference formation in monogamous voles. Behav Neurosci 109: 782-789.
99. Insel TR, Preston S, Winslow JT (1995) Mating in the monogamous male: behavioral consequences. Physiol Behav 57: 615-627.
100. Insel TR, Shapiro LE (1992) Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. Proc Natl Acad Sci USA 89: 5981-5985.
101. Insel TR, Wang Z, Ferris CF (1994) Patterns of brain vasopressin receptor distribution associated with social organization in microtine rodents. J Neurosci 14: 5381-5392.
102. Insel TR, Winslow JT, Wang Z, Young LJ (1998) Oxytocin, vasopressin, and the neuroendocrine basis of pair bond formation. Adv Exp Med Biol 449: 215-224.
103. Israel S, Lerer E, Shalev I, Uzefovsky F, Reibold M, Bachner-Melman R, Granot R, Bornstein G, Knafo A, Yirmiya N, Ebstein RP (2008) Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between. Prog Brain Res 170: 435-449.
104. Jackson D, Burns R, Trksak G, Simeone B, DeLeon KR, Connor DF, Harrison RJ, Melloni RH Jr (2005) Anterior hypothalamic vasopressin modulates the aggression-stimulating effects of adolescent cocaine exposure in Syrian hamsters. Neuroscience 133: 635-646.
105. Jannett F (1982) Nesting patterns of adult voles, Microtus montanus, in field populations. J Mamm 63: 495-498.
106. Johnson AE, Audigier S, Rossi F, Jard S, Tribollet E, Barberis C (1993) Localization and characterization of vasopressin binding sites in the rat brain using an iodinated linear AVP antagonist. Brain Res 622: 9-16.
107. Kaestner R (1995) The effects of cocaine and marijuana use on marriage and marital stability. National bureau of economic research working paper no. 5038.
108. Kandel DB, Rosenbaum E, Chen K (1994) Impact of maternal drug-use and life experiences on preadolescent children born to teenage mothers. J Marriage Fam 56: 325-340.
109. Katz LF, Ball GF, Nelson RJ (1999) Elevated Fos-like immunoreactivity in the brains of postpartum female prairie voles, Microtus ochrogaster. Cell Tissue Res 298: 425-435.
110. Kelley AE, Berridge KC (2002) The neuroscience of natural rewards: relevance to addictive drugs. J Neurosci 22: 3306-3311.
111. Kendrick KM (2004) The neurobiology of social bonds. J Neuroendocrinol 16: 1007-1008.
112. Kim SJ, Young LJ, Gonen D, Veenstra-VanderWeele J, Courchesne R, Courchesne E, Lord C, Leventhal BL, Cook EH Jr, Insel TR (2002) Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism. Mol Psychiatry 7: 503-507.
113. Kirkpatrick B, Kim JW, Insel TR (1994) Limbic system fos expression associated with paternal behavior. Brain Res 658: 112-118.
114. Knyshevski I, Connor DF, Harrison RJ, Ricci LA, Melloni RH Jr (2005a) Persistent activation of select forebrain regions in aggressive, adolescent cocaine-treated hamsters. Behav Brain Res 159: 277-286.
115. Knyshevski I, Ricci LA, McCann TE, Melloni RH Jr (2005b) Serotonin type-1A receptors modulate adolescent, cocaine-induced offensive aggression in hamsters. Physiol Behav 85: 167-176.
116. Koob GF (2000) Neurobiology of addiction. Toward the development of new therapies. Ann N Y Acad Sci 909: 170-185.
117. Koob GF, Le Moal M (2001) Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24: 97-129.
118. Koolhaas JM, Van den Brink THC, Roozendaal B, Boorsma F (1990) Medial amygdala and aggressive behavior: interaction between testosterone and vasopressin. Aggressive Behav 16: 223-229.
119. Kosten TR (1996) Basic neurobiology of abused drugs. NIDA Res Monogr 162: 54-56.
120. Kozorovitskiy Y, Hughes M, Lee K, Gould E (2006) Fatherhood affects dendritic spines and vasopressin V1a receptors in the primate prefrontal cortex. Nat Neurosci 9: 1094-1095.
121. Kramer KM, Choe C, Carter CS, Cushing BS (2006) Developmental effects of oxytocin on neural activation and neuropeptide release in response to social stimuli. Horm Behav 49: 206-214.
122. Krug EG, Dahlberg LL, Mercy JA, Zwi AB, Lozito R (2002) World report on violence and health. World Health Organization, Geneva.
123. Kruk MR (1991) Ethology and pharmacology of hypothalamic aggression in the rat. Neurosci Biobehav Rev 15: 527-538.
124. Kruk MR, Van der Laan CE, Mos J, Van der Poel AM, Meelis W, Olivier B (1984) Comparison of aggressive behaviour induced by electrical stimulation in the hypothalamus of male and female rats. Prog Brain Res 61: 303-314.
125. Kuptsov PA, Pleskacheva MG, Voronkova DN, Lipp HP, Anokhin KV (2005) Features of the c-Fos gene expression along the hippocampal rostro-caudal axis in common voles after rapid spatial learning. Zh Vyssh Nerv Deiat Im I P Pavlova 55: 231-240.
126. Landgraf R, Frank E, Aldag JM, Neumann ID, Sharer CA, Ren X, Terwilliger EF, Niwa M, Wigger A, Young LJ (2003) Viral vector-mediated gene transfer of the vole V1a vasopressin receptor in the rat septum: improved social discrimination and active social behaviour. Eur J Neurosci 18: 403-411.
127. Lansing SW, Lonstein JS (2006) Tyrosine hydroxylase-synthesizing cells in the hypothalamus of prairie voles (Microtus ochrogaster): sex differences in the anteroventral periventricular preoptic area and effects of adult gonadectomy or neonatal gonadal hormones. J Neurobiol 66: 197-204.
128. Lim MM, Wang Z, Olazabal DE, Ren X, Terwilliger EF, Young LJ (2004) Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene. Nature 429: 754-757.
129. Lim MM, Young LJ (2004) Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole. Neuroscience 125: 35-45.
130. Lin D, Boyle MP, Dollar P, Lee H, Lein ES, Perona P, Anderson DJ (2011) Functional identification of an aggression locus in the mouse hypothalamus. Nature 470: 221-226.
131. Lindvall O, Stenevi U (1978) Dopamine and noradrenaline neurons projecting to the septal area in the rat. Cell Tissue Res 190: 383-407.
132. Liu Y, Aragona BJ, Young KA, Dietz DM, Kabbaj M, Mazei-Robison M, Nestler EJ, Wang Z (2010) Nucleus accumbens dopamine mediates amphetamine-induced impairment of social bonding in a monogamous rodent species. Proc Natl Acad Sci U S A 107: 1217-1222.
133. Liu Y, Curtis JT, Wang Z (2001) Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster). Behav Neurosci 115: 910-919.
134. Liu Y, Wang Z (2003) Nucleus accumbens oxytocin and dopamine interact to regulate pair bond formation in female prairie voles. Neuroscience 121: 537-544.
135. Liu Y, Young KA, Curtis JT, Aragona BJ, Wang Z (2011) Social bonding decreases the rewarding properties of amphetamine through a dopamine D1 receptor-mediated mechanism. J Neurosci 31: 7960-7966.
136. Madan A, Beech DJ, Flint L (2001) Drugs, guns, and kids: the association between substance use and injury caused by interpersonal violence. J Pediatr Surg 36: 440-442.
137. Maeda H, Mogenson GJ (1980) An electrophysiological study of inputs to neurons of the ventral tegmental area from the nucleus accumbens and medial preoptic-anterior hypothalamic areas. Brain Res 197: 365-377.
138. Maldonado R (2003) The neurobiology of addiction. J Neural Transm Suppl 66: 1-14.
139. Marazziti D, Dell'Osso B, Baroni S, Mungai F, Catena M, Rucci P, Albanese F, Giannaccini G, Betti L, Fabbrini L, Italiani P, Del Debbio A, Lucacchini A, Dell'Osso L (2006) A relationship between oxytocin and anxiety of romantic attachment. Clin Pract Epidemol Ment Health 2: 28.
140. Marsden CA (2006) Dopamine: the rewarding years. Br J Pharmacol 147(Suppl 1): S136-S144.
141. Martel P, Fantino M (1996) Influence of the amount of food ingested on mesolimbic dopaminergic system activity: a microdialysis study. Pharmacol Biochem Behav 55: 297-302.
142. Mas M, Fumero B, Gonzalez-Mora JL (1995) Voltammetric and microdialysis monitoring of brain monoamine neurotransmitter release during sociosexual interactions. Behav Brain Res 71: 69-79.
143. McGuire B, Novak M (1984) A comparison of maternal behavior in the meadow vole (Microtus pennsylvanicus), prairie vole (M. ochrogaster) and pine vole (M. pinetorum). Anim Behav 32: 1132-1141.
144. McGuire B, Novak M (1986) Parental care and its relation to social organization in the montane vole. J Mammal 67: 305-311.
145. Meisel RL, Camp DM, Robinson TE (1993) A microdialysis study of ventral striatal dopamine during sexual behavior in female Syrian hamsters. Behav Brain Res 55: 151-157.
146. Melloni RH Jr, Connor DF, Hang PT, Harrison RJ, Ferris CF (1997) Anabolic-androgenic steroid exposure during adolescence and aggressive behavior in golden hamsters. Physiol Behav 61: 359-364.
147. Melloni RH Jr, Connor DF, Todtenkopf MS, DeLeon KR, Sanyal P, Harrison RJ (2001) Repeated cocaine treatment activates flank marking in adolescent female hamsters. Physiol Behav 73: 561-570.
148. Melloni RH Jr, Ferris CF (1996) Adolescent anabolic steroid use and aggressive behavior in golden hamsters. Ann N Y Acad Sci 794: 372-375.
149. Meyer-Lindenberg A, Kolachana B, Gold B, Olsh A, Nicodemus KK, Mattay V, Dean M, Weinberger DR (2009) Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans. Mol Psychiatry 10: 968-975.
150. Michard-Vanhee C (1988) Aggressive behavior induced in female mice by an early single injection of testosterone is genotype dependent. Behav Genet 18: 1-12.
151. Michell RH, Kirk CJ, Billah MM (1979) Hormonal stimulation of phosphatidylinositol breakdown with particular reference to the hepatic effects of vasopressin. Biochem Soc Trans 7: 861-865.
152. Miczek KA (1979) A new test for aggression in rats without aversive stimulation: differential effects of d-amphetamine and cocaine. Psychopharmacology 60: 253-259.
153. Miczek KA, de Almeida RM, Kravitz EA, Rissman EF, de Boer SF, Raine A (2007) Neurobiology of escalated aggression and violence. J Neurosci 27: 11803-11806.
154. Mokuau N (2002) Culturally based interventions for substance use and child abuse among native Hawaiians. Public Health Rep 117(Suppl 1): S82-S87.
155. Moore TM, Stuart GL, Meehan JC, Rhatigan DL, Hellmuth JC, Keen SM (2008) Drug abuse and aggression between intimate partners: a meta-analytic review. Clin Psychol Rev 28: 247-274.
156. Moos RH, Nichol AC, Moos BS (2002) Risk factors for symptom exacerbation among treated patients with substance use disorders. Addiction 97: 75-85.
157. Moses J, Loucks JA, Watson HL, Matuszewich L, Hull EM (1995) Dopaminergic drugs in the medial preoptic area and nucleus accumbens: effects on motor activity, sexual motivation, and sexual performance. Pharmacol Biochem Behav 51: 681-686.
158. Motta SC, Goto M, Gouveia FV, Baldo MV, Canteras NS, Swanson LW (2009) Dissecting the brain's fear system reveals the hypothalamus is critical for responding in subordinate conspecific intruders. Proc Natl Acad Sci U S A 106(12): 4870-4875.
159. Murphy TH, Worley PF, Baraban JM (1991) L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes. Neuron 7: 625-635.
160. Neill DB, Fenton H, Justice JB Jr (2002) Increase in accumbal dopaminergic transmission correlates with response cost not reward of hypothalamic stimulation. Behav Brain Res 137: 129-138.
161. Nesse RM, Berridge KC (1997) Psychoactive drug use in evolutionary perspective. Science 278: 63-66.
162. Nestler EJ, Aghajanian GK (1997) Molecular and cellular basis of addiction. Science 278: 58-63.
163. Nestler EJ, Malenka RC (2004) The addicted brain. Sci Am 290: 78-85.
164. Neve KA, Seamans JK, Trantham-Davidson H (2004) Dopamine receptor signaling. J Recept Signal Transduct Res 24: 165-205.
165. Newman SW (1999) The medial extended amygdala in male reproductive behavior. A node in the mammalian social behavior network. Ann N Y Acad Sci 877: 242-257.
166. Northcutt KV, Lonstein JS (2009) Social contact elicits immediate-early gene expression in dopaminergic cells of the male prairie vole extended olfactory amygdala. Neuroscience 163: 9-22.
167. Northcutt KV, Wang Z, Lonstein JS (2007) Sex and species differences in tyrosine hydroxylasesynthesizing cells of the rodent olfactory extended amygdala. J Comp Neurol 500: 103-115.
168. O'Farrell TJ, Fals-Stewart W (2000) Behavioral couples therapy for alcoholism and drug abuse. J Subst Abuse Treat 18: 51-54.
169. Oliveras D, Novak M (1986) A comparison of paternal behavior in the meadow vole, Microtus pennsylvanicus, the pine vole, Microtus pinetorum, and prairie vole, Microtus ochrogaster. Anim Behav 34: 519-526.
170. Ophir AG, Wolff JO, Phelps SM (2008) Variation in neural V1aR predicts sexual fidelity and space use among male prairie voles in semi-natural settings. Proc Natl Acad Sci U S A 105: 1249-1254.
171. Panksepp J, Knutson B, Burgdorf J (2002) The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model. Addiction 97: 459-469.
172. Pecina S, Cagniard B, Berridge KC, Aldridge JW, Zhuang X (2003) Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards. J Neurosci 23: 9395-9402.
173. Pedersen CA (2004) Biological aspects of social bonding and the roots of human violence. Ann N Y Acad Sci 1036: 106-127.
174. Pfaus JG, Damsma G, Nomikos GG, Wenkstern DG, Blaha CD, Phillips AG, Fibiger HC (1990) Sexual behavior enhances central dopamine transmission in the male rat. Brain Res 530: 345-348.
175. Pitkow LJ, Sharer CA, Ren X, Insel TR, Terwilliger EF, Young LJ (2001) Facilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole. J Neurosci 21: 7392-7396.
176. Pollack A (2004) Coactivation of D1 and D2 dopamine receptors: in marriage, a case of his, hers, and theirs. Sci STKE 2004: pe50.
177. Prichard ZM, Mackinnon AJ, Jorm AF, Easteal S (2007) AVPR1A and OXTR polymorphisms are associated with sexual and reproductive behavioral phenotypes in humans. Mutation in brief no. 981. Online. Hum Mutat 28: 1150.
178. Raggenbass M, Goumaz M, Sermasi E, Tribollet E, Dreifuss JJ (1991) Vasopressin generates a persistent voltage-dependent sodium current in a mammalian motoneuron. J Neurosci 11: 1609-1616.
179. Ramamurthi B (1988) Stereotactic operation in behaviour disorders Amygdalotomy and hypothalamotomy. Acta Neurochir Suppl 44: 152-157.
180. Resendez SL, Kuhnmuench M, Krzywosinski T, Aragona BJ (2012) kappa-Opioid receptors within the nucleus accumbens shell mediate pair bond maintenance. J Neurosci 32: 6771-6784.
181. Ricci LA, Schwartzer JJ, Melloni RH Jr (2009) Alterations in the anterior hypothalamic dopamine system in aggressive adolescent AAS-treated hamsters. Horm Behav 55: 348-355.
182. Riters LV, Panksepp J (1997) Effects of vasotocin on aggressive behavior in male Japanese quail. Ann N Y Acad Sci 807: 478-480.
183. Roeling TA, Kruk MR, Schuurmans R, Veening JG (1993) Behavioural responses of bicucculline methiodide injections into the ventral hypothalamus of freely moving, socially interacting rats. Brain Res 615: 121-127.
184. Ryding E, Lindstrom M, Traskman-Bendz L (2008) The role of dopamine and serotonin in suicidal behaviour and aggression. Prog Brain Res 172: 307-315.
185. Sano K, Yoshioka M, Ogashiwa M, Ishijima B, Ohye C (1966) Postero-medial hypothalamotomy in the treatment of aggressive behaviors. Confin Neurol 27: 164-167.
186. Schwartzer JJ, Melloni RH Jr (2010a) Anterior hypothalamic dopamine D2 receptors modulate adolescent anabolic/androgenic steroid-induced offensive aggression in the Syrian hamster. Behav Pharmacol 21: 314-322.
187. Schwartzer JJ, Melloni RH Jr (2010b) Dopamine activity in the lateral anterior hypothalamus modulates AAS-induced aggression through D2 but not D5 receptors. Behav Neurosci 124: 645-655.
188. Schwartzer JJ, Ricci LA, Melloni RH Jr (2009) Interactions between the dopaminergic and GABAergic neural systems in the lateral anterior hypothalamus of aggressive AAS-treated hamsters. Behav Brain Res 203: 15-22.
189. Self DW, Barnhart WJ, Lehman DA, Nestler EJ (1996) Opposite modulation of cocaine-seeking behavior by D1-and D2-like dopamine receptor agonists. Science 271: 1586-1589.
190. Self DW, Genova LM, Hope BT, Barnhart WJ, Spencer JJ, Nestler EJ (1998) Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. J Neurosci 18: 1848-1859.
191. Siegel A, Roeling TA, Gregg TR, Kruk MR (1999) Neuropharmacology of brain-stimulationevoked aggression. Neurosci Biobehav Rev 23: 359-389.
192. Siever LJ (2008) Neurobiology of aggression and violence. Am J Psychiatry 165: 429-442.
193. Smeltzer MD, Curtis JT, Aragona BJ, Wang Z (2006) Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles. Neurosci Lett 394: 146-151.
194. Son MC, Brinton RD (2001) Regulation and mechanism of L-type calcium channel activation via V1a vasopressin receptor activation in cultured cortical neurons. Neurobiol Learn Mem 76: 388-402.
195. Spunt B, Brownstein HH, Crimmins SM, Langley S, Spanjol K (1998) Alcohol-related homicides committed by women. J Psychoactive Drugs 30: 33-43.
196. Stowe JR, Liu Y, Curtis JT, Freeman ME, Wang Z (2005) Species differences in anxiety-related responses in male prairie and meadow voles: the effects of social isolation. Physiol Behav 86: 369-378.
197. Stribley JM, Carter CS (1999) Developmental exposure to vasopressin increases aggression in adult prairie voles. Proc Natl Acad Sci U S A 96: 12601-12604.
198. Surmeier DJ, Ding J, Day M, Wang Z, Shen W (2007) D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons. Trends Neurosci 30: 228-235.
199. Swain JE, Lorberbaum JP, Kose S, Strathearn L (2007) Brain basis of early parent-infant interactions: psychology, physiology, and in vivo functional neuroimaging studies. J Child Psychol Psychiatry 48: 262-287.
200. Swanson LW (1982) The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res Bull 9: 321-353.
201. Swartz MS, Swanson JW, Hiday VA, Borum R, Wagner HR, Burns BJ (1998) Violence and severe mental illness: the effects of substance abuse and nonadherence to medication. Am J Psychiatry 155: 226-231.
202. Tamarin R (1985) Biology of New World Microtus. Am Soc Mamm Spec Pub 8. Shippensburg, PA.
203. Thibonnier M (1992) Signal transduction of V1-vascular vasopressin receptors. Regul Pept 38: 1-11.
204. Thibonnier M, Auzan C, Madhun Z, Wilkins P, Berti-Mattera L, Clauser E (1994) Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor. J Biol Chem 269: 3304-3310.
205. Thibonnier M, Bayer AL, Simonson MS, Douglas JG (1992) Effects of amiloride analogues on AVP binding and activation of V1-receptor-expressing cells. Am J Physiol 262: E76-E86.
206. Thibonnier M, Goraya T, Berti-Mattera L (1993) G protein coupling of human platelet V1 vascular vasopressin receptors. Am J Physiol 264: C1336-C1344.
207. Thompson R, Gupta S, Miller K, Mills S, Orr S (2004) The effects of vasopressin on human facial responses related to social communication. Psychoneuroendocrinology 29: 35-48.
208. Tidey JW, Miczek KA (1992) Morphine withdrawal aggression: modification with D1 and D2 receptor agonists. Psychopharmacology 108: 177-184.
209. Triemstra JL, Nagatani S, Wood RI (2005) Chemosensory cues are essential for mating-induced dopamine release in MPOA of male Syrian hamsters. Neuropsychopharm 30: 1436-1442.
210. Tubbiola ML, Wysocki CJ (1997) FOS immunoreactivity after exposure to conspecific or heterospecific urine: where are chemosensory cues sorted? Physiol Behav 62: 867-870.
211. Vale JR, Ray D, Vale CA (1972) The interaction of genotype and exogenous neonatal androgen: agonistic behavior in female mice. Behav Biol 7: 321-334.
212. Veenema AH, Beiderbeck DI, Lukas M, Neumann ID (2010) Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression. Horm Behav 58: 273-281.
213. Veenema AH, Blume A, Niederle D, Buwalda B, Neumann ID (2006) Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin. Eur J Neurosci 24: 1711-1720.
214. Veening JG, Coolen LM, de Jong TR, Joosten HW, de Boer SF, Koolhaas JM, Olivier B (2005) Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies. Eur J Pharmacol 526: 226-239.
215. Villalba C, Boyle PA, Caliguri EJ, De Vries GJ (1997) Effects of the selective serotonin reuptake inhibitor fluoxetine on social behaviors in male and female prairie voles (Microtus ochrogaster). Horm Behav 32: 184-191.
216. Volkow ND, Wang GJ, Fowler JS, Logan J, Jayne M, Franceschi D, Wong C, Gatley SJ, Gifford AN, Ding YS, Pappas N (2002) "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse 44: 175-180.
217. Walsh C, MacMillan HL, Jamieson E (2003) The relationship between parental substance abuse and child maltreatment: findings from the Ontario Health Supplement. Child Abuse Negl 27: 1409-1425.
218. Walum H, Westberg L, Henningsson S, Neiderhiser JM, Reiss D, Igl W, Ganiban JM, Spotts EL, Pedersen NL, Eriksson E, Lichtenstein P (2008) Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. Proc Natl Acad Sci U S A 105: 14153-14156.
219. Wang GJ, Volkow ND, Fowler JS (2002) The role of dopamine in motivation for food in humans: implications for obesity. Expert Opin Ther Targets 6: 601-609.
220. Wang Z (1995) Species differences in the vasopressin-immunoreactive pathways in the bed nucleus of the stria terminalis and medial amygdaloid nucleus in prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus). Behav Neurosci 109: 305-311.
221. Wang Z, Aragona BJ (2004) Neurochemical regulation of pair bonding in male prairie voles. Physiol Behav 83: 319-328.
222. Wang Z, Hulihan TJ, Insel TR (1997a) Sexual and social experience is associated with different patterns of behavior and neural activation in male prairie voles. Brain Res 767: 321-332.
223. Wang Z, Liu Y, Young LJ, Insel TR (1997b) Developmental changes in forebrain vasopressin receptor binding in prairie voles (Microtus ochrogaster) and montane voles (Microtus montanus). Ann N Y Acad Sci 807: 510-513.
224. Wang Z, Smith W, Major DE, De Vries GJ (1994) Sex and species differences in the effects of cohabitation on vasopressin messenger RNA expression in the bed nucleus of the stria terminalis in prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus). Brain Res 650: 212-218.
225. Wang Z, Young LJ, De Vries GJ, Insel TR (1998) Voles and vasopressin: a review of molecular, cellular, and behavioral studies of pair bonding and paternal behaviors. Prog Brain Res 119: 483-499.
226. Wang Z, Yu G, Cascio C, Liu Y, Gingrich B, Insel TR (1999) Dopamine D2 receptor-mediated regulation of partner preferences in female prairie voles (Microtus ochrogaster): a mechanism for pair bonding? Behav Neurosci 113: 602-611.
227. Wang Z, Zhou L, Hulihan TJ, Insel TR (1996) Immunoreactivity of central vasopressin and oxytocin pathways in microtine rodents: a quantitative comparative study. J Comp Neurol 366: 726-737.
228. Wang Z, Young LJ, Liu Y, Insel TR (1997c) Species differences in vasopressin receptor binding are evident early in development: comparative anatomic studies in prairie and montane voles. J Comp Neurol 378: 535-546.
229. Wersinger SR, Rissman EF (2000) Dopamine activates masculine sexual behavior independent of the estrogen receptor alpha. J Neurosci 20: 4248-4254.
230. White FJ, Kalivas PW (1998) Neuroadaptations involved in amphetamine and cocaine addiction. Drug Alcohol Depend 51: 141-153.
231. Williams JR, Carter CS, Insel T (1992) Partner preference development in female prairie voles is facilitated by mating or the central infusion of oxytocin. Ann N Y Acad Sci 652: 487-489.
232. Williams JR, Insel TR, Harbaugh CR, Carter CS (1994) Oxytocin administered centrally facilitates formation of a partner preference in female prairie voles (Microtus ochrogaster). J Neuroendocrinol 6: 247-250.
233. Winn P, Robbins TW (1985) Comparative effects of infusions of 6-hydroxydopamine into nucleus accumbens and anterolateral hypothalamus induced by 6-hydroxydopamine on the response to dopamine agonists, body weight, locomotor activity and measures of exploration in the rat. Neuropharm 24: 25-31.
234. Winslow JT, Hastings N, Carter CS, Harbaugh CR, Insel TR (1993) A role for central vasopressin in pair bonding in monogamous prairie voles. Nature 365: 545-548.
235. Wise RA (2002) Brain reward circuitry: insights from unsensed incentives. Neuron 36: 229-240.
236. Wommack JC, Wang Z (2007) Dopamine in the prefrontal cortex regulates partner preference formation in female prairie voles. Poster P1. 28, presented at the society for behavioral neuroendocrinology, Pacific Grove, CA.
237. Yamada S, Uchida S, Ohkura T, Kimura R, Yamaguchi M, Suzuki M, Yamamoto M (1996) Alterations in calcium antagonist receptors and calcium content in senescent brain and attenuation by nimodipine and nicardipine. J Pharmacol Exp Ther 277: 721-727.
238. Yamaguchi K, Kandel DB (1985) On the resolution of role incompatibility-A life event history analysis of family roles and marijuana use. Am J Sociol 90: 1284-1325.
239. Young KA, Gobrogge KL, Liu Y, Wang Z (2011a) The neurobiology of pair bonding: Insights from a socially monogamous rodent. Front Neuroendocrinol 32: 53-69.
240. Young KA, Gobrogge KL, Wang Z (2011b) The role of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior. Neurosci Biobehav Rev 35: 498-515.
241. Young KA, Liu Y, Wang Z (2008) The neurobiology of social attachment: A comparative approach to behavioral, neuroanatomical, and neurochemical studies. Comp Biochem Physiol C: Toxicol Pharmacol 148: 401-410.
242. Young LJ (1999) Frank A. Beach Award. Oxytocin and vasopressin receptors and species-typical social behaviors. Horm Behav 36: 212-221.
243. Young LJ, Nilsen R, Waymire KG, MacGregor GR, Insel TR (1999) Increased affiliative response to vasopressin in mice expressing the V1a receptor from a monogamous vole. Nature 400: 766-768.
244. Young LJ, Wang Z (2004) The neurobiology of pair bonding. Nat Neurosci 7: 1048-1054.
245. Young LJ, Wang Z, Insel TR (1998) Neuroendocrine bases of monogamy. Trends Neurosci 21: 71-75.
246. Young LJ, Winslow JT, Nilsen R, Insel TR (1997) Species differences in V1a receptor gene expression in monogamous and nonmonogamous voles: behavioral consequences. Behav Neurosci 111: 599-605.
247. Yun IA, Wakabayashi KT, Fields HL, Nicola SM (2004) The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. J Neurosci 24: 2923-2933.
248. Zeiss CJ (2005) Neuroanatomical phenotyping in the mouse: the dopaminergic system. Vet Pathol 42: 753-773.