Alterations in the anterior hypothalamic dopamine system in aggressive adolescent AAS-treated hamsters

Hormones and Behavior

Volumn 55, Issue 2, 2009, Pages 348-355

  Ricci, Lesley A ^a   Schwartzer, Jared J ^a   Melloni Jr , Richard H ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Adolescent AAS; Aggression; AH; D2; Dopamine; TH

Indexed keywords

ANDROSTANOLONE; DOPAMINE; DOPAMINE 2 RECEPTOR; NANDROLONE; SESAME SEED OIL; TESTOSTERONE CIPIONATE; TYROSINE 3 MONOOXYGENASE;

ADOLESCENT; AGGRESSION; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DOPAMINE METABOLISM; DOPAMINERGIC SYSTEM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LATERAL HYPOTHALAMUS; MALE; NERVE CELL PLASTICITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTUM PELLUCIDUM; STRIA TERMINALIS; SUPRAOPTIC NUCLEUS; SYRIAN HAMSTER;

AGGRESSION; AMYGDALA; ANIMALS; BEHAVIOR, ANIMAL; CRICETINAE; DOPAMINE; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MESOCRICETUS; PHOTOMICROGRAPHY; RECEPTORS, DOPAMINE D2; SEPTAL NUCLEI; SEPTUM OF BRAIN; STEROIDS; TYROSINE 3-MONOOXYGENASE;

EID: 58849085418     PISSN: 0018506X     EISSN: 10956867     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2008.10.011     Document Type: Article

References (75)

1. Adams B.W., and Moghaddam B. Tactile stimulation activates dopamine release in the lateral septum. Brain Res. 858 (2000) 177-180
2. Angulo J.A., Printz D., Ledoux M., and McEwen B.S. Isolation stress increases tyrosine hydroxylase mRNA in the locus coeruleus and midbrain and decreases proenkephalin mRNA in the striatum and nucleus accumbens. Brain Res. Mol. Brain Res. 11 (1991) 301-308
3. Arregui A., Azpiroz A., Brain P.F., and Simon V. Effects of two selective dopaminergic antagonists on ethologically-assessed encounters in male mice. Gen. Pharmacol. 24 (1993) 353-356
4. Asmus S.E., and Newman S.W. Tyrosine hydroxylase neurons in the male hamster chemosensory pathway contain androgen receptors and are influenced by gonadal hormones. J. Comp. Neurol. 331 (1993) 445-457
5. Asmus S.E., Kincaid A.E., and Newman S.W. A species-specific population of tyrosine hydroxylase-immunoreactive neurons in the medial amygdaloid nucleus of the Syrian hamster. Brain Res. 575 (1992) 199-207
6. Azdad K., Piet R., Poulain D.A., and Oliet S.H. Dopamine D4 receptor-mediated presynaptic inhibition of GABAergic transmission in the rat supraoptic nucleus. J. Neurophysiol. 90 (2003) 559-565
7. Baggio G., and Ferrari F. Role of brain dopaminergic mechanisms in rodent aggressive behavior: influence of (+/-)N-n-propyl-norapomorphine on three experimental models. Psychopharmacology 70 (1980) 63-68
8. Baimoukhametova D.V., Hewitt S.A., Sank C.A., and Bains J.S. Dopamine modulates use-dependent plasticity of inhibitory synapses. J. Neurosci. 24 (2004) 5162-5171
9. Boundy V.A., Luedtke R.R., Artymyshyn R.P., Filtz T.M., and Molinoff P.B. Development of polyclonal anti-D2 dopamine receptor antibodies using sequence-specific peptides. Mol. Pharmacol. 43 (1993) 666-676
10. Buckley W.E., Yesalis III C.E., Friedl K.E., Anderson W.A., Streit A.L., and Wright J.E. Estimated prevalence of anabolic steroid use among male high school seniors. JAMA 260 (1988) 3441-3445
11. Carrillo, M., Ricci, L.A., Melloni, R.H., Jr., in press. Adolescent anabolic steroids reorganize the glutamatergic neural circuitry in the hypothalamus. Brain Research
12. Chernigovskaia E.V., Glazova M.V., Iamova L.A., Evteeva S.E., and Krasnovskaia I.A. Catecholamines in the regulation of the functional state of vasopressinergic cells in the rat hypothalamus. Zh. Evol. Biokhim. Fiziol. 37 (2001) 144-149
13. Christophersen N.S., Meijer X., Jorgensen J.R., Englund U., Gronborg M., Seiger A., Brundin P., and Wahlberg L.U. Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain. Brain Res. Bull. 70 (2006) 457-466
14. Coccaro E.F., Kavoussi R.J., Hauger R.L., Cooper T.B., and Ferris C.F. Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects. Arch. Gen. Psychiatry 55 (1998) 708-714
15. DeLeon K.R., Grimes J.M., Connor D.F., and Melloni Jr. R.H. Adolescent cocaine exposure and offensive aggression: involvement of serotonin neural signaling and innervation in male Syrian hamsters. Behav. Brain Res. 133 (2002) 211-220
16. Delville Y., De Vries G.J., and Ferris C.F. Neural connections of the anterior hypothalamus and agonistic behavior in golden hamsters. Brain Behav. Evol. 55 (2000) 53-76
17. Ellison G. Monoamine neurotoxins: selective and delayed effects on behavior in colonies of laboratory rats. Brain Res. 103 (1976) 81-92
18. Extein I. Psychopharmacology in psychiatric emergencies. Int. J. Psychiatry Med. 10 (1980) 189-204
19. Ferrari F., and Giuliani D. Behavioural assessment in rats of the antipsychotic potential of the potent dopamine D2 receptor antagonist, (-)eticlopride. Pharmacol. Res. 31 (1995) 261-267
20. Ferrari P.F., van Erp A.M., Tornatzky W., and Miczek K.A. Accumbal dopamine and serotonin in anticipation of the next aggressive episode in rats. Eur. J. Neurosci. 17 (2003) 371-378
21. Ferris C.F., and Potegal M. Vasopressin receptor blockade in the anterior hypothalamus suppresses aggression in hamsters. Physiol. Behav. 44 (1988) 235-239
22. Ferris C.F., Albers H.E., Wesolowski S.M., Goldman B.D., and Luman S.E. Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters. Science (New York, NY 224 (1984) 521-523
23. Ferris C.F., Melloni Jr. R.H., Koppel G., Perry K.W., Fuller R.W., and Delville Y. Vasopressin/serotonin interactions in the anterior hypothalamus control aggressive behavior in golden hamsters. J. Neurosci. 17 (1997) 4331-4340
24. Filipenko M.L., Alekseyenko O.V., Beilina A.G., Kamynina T.P., and Kudryavtseva N.N. Increase of tyrosine hydroxylase and dopamine transporter mRNA levels in ventral tegmental area of male mice under influence of repeated aggression experience. Brain Res. Mol. Brain Res. 96 (2001) 77-81
25. Fischer S.G., Ricci L.A., and Melloni Jr. R.H. Repeated anabolic/androgenic steroid exposure during adolescence alters phosphate-activated glutaminase and glutamate receptor 1 (GluR1) subunit immunoreactivity in Hamster brain: correlation with offensive aggression. Behav. Brain Res. 180 (2007) 77-85
26. Floody O.R., and Pfaff D.W. Aggressive behavior in female hamsters: the hormonal basis for fluctuations in female aggressiveness correlated with estrous state. J. Comp. Physiol. Psychol. 91 (1977) 443-464
27. Forsling M.L., and Williams H. Central effects of dopamine on vasopressin release in the normally hydrated and water-loaded rat. J. Physiol. 346 (1984) 49-59
28. Gendreau P.L., Petitto J.M., Gariepy J.L., and Lewis M.H. D2-like dopamine receptor mediation of social-emotional reactivity in a mouse model of anxiety: strain and experience effects. Neuropsychopharmacology 18 (1998) 210-221
29. Gies U., and Theodosis D.T. Synaptic plasticity in the rat supraoptic nucleus during lactation involves GABA innervation and oxytocin neurons: a quantitative immunocytochemical analysis. J. Neurosci. 14 (1994) 2861-2869
30. Gobrogge K.L., Liu Y., Jia X., and Wang Z. Anterior hypothalamic neural activation and neurochemical associations with aggression in pair-bonded male prairie voles. J. Comp. Neurol. 502 (2007) 1109-1122
31. Grimes J.M., and Melloni Jr. R.H. Serotonin modulates offensive attack in adolescent anabolic steroid-treated hamsters. Pharmacol. Biochem. Behav. 73 (2002) 713-721
32. Grimes J.M., Ricci L.A., and Melloni Jr. R.H. Glutamic acid decarboxylase (GAD65) immunoreactivity in brains of aggressive, adolescent anabolic steroid-treated hamsters. Horm. Behav. 44 (2003) 271-280
33. Grimes J.M., Ricci L.A., and Melloni Jr. R.H. Plasticity in anterior hypothalamic vasopressin correlates with aggression during anabolic-androgenic steroid withdrawal in hamsters. Behav. Neurosci. 120 (2006) 115-124
34. Grimes J.M., Ricci L.A., and Melloni Jr. R.H. Alterations in anterior hypothalamic vasopressin, but not serotonin, correlate with the temporal onset of aggressive behavior during adolescent anabolic-androgenic steroid exposure in hamsters (Mesocricetus auratus). Behav. Neurosci. 121 (2007) 941-948
35. Harrison R.J., Connor D.F., Nowak C., Nash K., and Melloni Jr. R.H. Chronic anabolic-androgenic steroid treatment during adolescence increases anterior hypothalamic vasopressin and aggression in intact hamsters. Psychoneuroendocrinology 25 (2000) 317-338
36. Kimura T., Share L., Wang B.C., and Crofton J.T. Central effects of dopamine and bromocriptine on vasopressin release and blood pressure. Neuroendocrinology 33 (1981) 347-351
37. Kindlundh A.M., Lindblom J., Bergstrom L., Wikberg J.E., and Nyberg F. The anabolic-androgenic steroid nandrolone decanoate affects the density of dopamine receptors in the male rat brain. Eur. J. Neurosci. 13 (2001) 291-296
38. Kindlundh A.M., Lindblom J., and Nyberg F. Chronic administration with nandrolone decanoate induces alterations in the gene-transcript content of dopamine D(1)- and D(2)-receptors in the rat brain. Brain Res. 979 (2003) 37-42
39. Knepel W., Nutto D., and Hertting G. Evidence for the involvement of a GABA-mediated inhibition in the hypovolaemia-induced vasopressin release. Pflugers Arch. 388 (1980) 177-183
40. Lamprecht F., Eichelman B., Thoa N.B., Williams R.B., and Kopin I.J. Rat fighting behavior: serum dopamine-β-hydroxylase and hypothalamic tyrosine hydroxylase. Science (New York, NY 177 (1972) 1214-1215
41. Leibowitz S.F., Jhanwar-Uniyal M., Dvorkin B., and Makman M.H. Distribution of alpha-adrenergic, beta-adrenergic and dopaminergic receptors in discrete hypothalamic areas of rat. Brain Res. 233 (1982) 97-114
42. Lerwill C.J., and Makaings P. The agonistic behavior of the golden hamster. Anim. Behav. 19 (1971) 714-721
43. Lindvall O., Bjorklund A., and Skagerberg G. Selective histochemical demonstration of dopamine terminal systems in rat di- and telencephalon: new evidence for dopaminergic innervation of hypothalamic neurosecretory nuclei. Brain Res. 306 (1984) 19-30
44. Louilot A., Le Moal M., and Simon H. Differential reactivity of dopaminergic neurons in the nucleus accumbens in response to different behavioral situations. An in vivo voltammetric study in free moving rats. Brain Res. 397 (1986) 395-400
45. Mansour A., Meador-Woodruff J.H., Bunzow J.R., Civelli O., Akil H., and Watson S.J. Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. J. Neurosci. 10 (1990) 2587-2600
46. Margolis E.B., Lock H., Hjelmstad G.O., and Fields H.L. The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?. J. Physiol. 577 (2006) 907-924
47. Marsh K.E., Creutz L.M., Hawkins M.B., and Godwin J. Aromatase immunoreactivity in the bluehead wrasse brain, Thalassoma bifasciatum: immunolocalization and co-regionalization with arginine vasotocin and tyrosine hydroxylase. Brain Res. 1126 (2006) 91-101
48. Matsuda T., Sakaue M., Ago Y., Sakamoto Y., Koyama Y., and Baba A. Functional alteration of brain dopaminergic system in isolated aggressive mice. Nihon Shinkei Seishin Yakurigaku Zasshi 21 (2001) 71-76
49. Melloni Jr. R.H., Connor D.F., Hang P.T., Harrison R.J., and Ferris C.F. Anabolic-androgenic steroid exposure during adolescence and aggressive behavior in golden hamsters. Physiol. Behav. 61 (1997) 359-364
50. Moos F., and Richard P. Excitatory effect of dopamine on oxytocin and vasopressin reflex releases in the rat. Brain Res. 241 (1982) 249-260
51. Morin L.P., and Wood R.I. A Stereotaxic Atlas of The Golden Hamster Brain (2001), Academic Press
52. Navarro J.F., and Manzaneque J.M. Acute and subchronic effects of tiapride on isolation-induced aggression in male mice. Pharmacol. Biochem. Behav. 58 (1997) 255-259
53. NIDACapsules (2006) http://www.nida.nih.gov/Infofacts/steroids.html. In.
54. Northcutt K.V., Wang Z., and Lonstein J.S. Sex and species differences in tyrosine hydroxylase-synthesizing cells of the rodent olfactory extended amygdala. J. Comp. Neurol. 500 (2007) 103-115
55. Pirnik Z., and Kiss A. Fos expression variances in mouse hypothalamus upon physical and osmotic stimuli: co-staining with vasopressin, oxytocin, and tyrosine hydroxylase. Brain Res. Bull. 65 (2005) 423-431
56. Puglisi-Allegra S., and Cabib S. Pharmacological evidence for a role of D2 dopamine receptors in the defensive behavior of the mouse. Behav. Neural Biol. 50 (1988) 98-111
57. Putnam S.K., Sato S., and Hull E.M. Effects of testosterone metabolites on copulation and medial preoptic dopamine release in castrated male rats. Horm. Behav. 44 (2003) 419-426
58. Ricci L.A., Rasakham K., Grimes J.M., and Melloni Jr. R.H. Serotonin-1A receptor activity and expression modulate adolescent anabolic/androgenic steroid-induced aggression in hamsters. Pharmacol. Biochem. Behav. 85 (2006) 1-11
59. Ricci L.A., Grimes J.M., and Melloni Jr. R.H. Lasting changes in neuronal activation patterns in select forebrain regions of aggressive, adolescent anabolic/androgenic steroid-treated hamsters. Behav. Brain Res. 176 (2007) 344-352
60. Ricci L.A., Connor D.F., Morrison R., and Melloni Jr. R.H. Risperidone exerts potent anti-aggressive effects in a developmentally immature animal model of escalated aggression. Biol. Psychiatry 62 (2007) 218-225
61. Rodriguez-Arias M., Minarro J., Aguilar M.A., Pinazo J., and Simon V.M. Effects of risperidone and SCH 23390 on isolation-induced aggression in male mice. Eur. Neuropsychopharmacol. 8 (1998) 95-103
62. Rodriguiz R.M., Chu R., Caron M.G., and Wetsel W.C. Aberrant responses in social interaction of dopamine transporter knockout mice. Behav. Brain Res. 148 (2004) 185-198
63. Sanghera M.K., Grady S., Smith W., Woodward D.J., and Porter J.C. Incertohypothalamic A13 dopamine neurons: effect of gonadal steroids on tyrosine hydroxylase. Neuroendocrinology 53 (1991) 268-275
64. Schwartzer J.J., Connor D.F., Morrison R., Ricci L.A., and Melloni Jr. R.H. Repeated risperidone administration during puberty suppresses the generation of the highly aggressive phenotype in a developmentally immature animal model of escalated aggression. Physiol. Behav. 95 1-2 (2008) 176-181
65. Schwartzer, J.J., Morrison, R., Ricci, L.A., Melloni, R.H., Jr., in press. Acute and repeated exposure to paliperidone suppresses the development of the aggressive phenotype in a developmentally sensitive animal model of escalated aggression. Psychopharm
66. Serova L.I., and Naumenko E.V. Involvement of the brain catecholaminergic system in the regulation of dominant behavior. Pharmacol. Biochem. Behav. 53 (1996) 285-290
67. Shi H., and Bartness T.J. Catecholaminergic enzymes, vasopressin and oxytocin distribution in Siberian hamster brain. Brain Res. Bull. 53 (2000) 833-843
68. Sibley D.R., Monsma Jr. F.J., and Shen Y. Molecular neurobiology of dopaminergic receptors. Int. Rev. Neurobiol. 35 (1993) 391-415
69. Sweidan S., Edinger H., and Siegel A. D2 dopamine receptor-mediated mechanisms in the medial preoptic-anterior hypothalamus regulate effective defense behavior in the cat. Brain Res. 549 (1991) 127-137
70. van Erp A.M., and Miczek K.A. Aggressive behavior, increased accumbal dopamine, and decreased cortical serotonin in rats. J. Neurosci. 20 (2000) 9320-9325
71. Weiner D.M., Levey A.I., Sunahara R.K., Niznik H.B., O'Dowd B.F., Seeman P., and Brann M.R. D1 and D2 dopamine receptor mRNA in rat brain. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 1859-1863
72. Wilczynski W., Yang E.J., and Simmons D. Sex differences and hormone influences on tyrosine hydroxylase immunoreactive cells in the leopard frog. J. Neurobiol. 56 (2003) 54-65
73. Wommack J.C., and Delville Y. Chronic social stress during puberty enhances tyrosine hydroxylase immunoreactivity within the limbic system in golden hamsters. Brain Res. 933 (2002) 139-143
74. Yesalis C.E., Kennedy N.J., Kopstein A.N., and Bahrke M.S. Anabolic-androgenic steroid use in the United States. JAMA 270 (1993) 1217-1221
75. Yesalis C.E., Barsukiewicz C.K., Kopstein A.N., and Bahrke M.S. Trends in anabolic-androgenic steroid use among adolescents. Arch. Pediatr. Adolesc. Med. 151 (1997) 1197-1206