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Volumn 51, Issue 4, 2014, Pages 273-281

Mutation Position Within Evolutionary Subclonal Architecture in AML

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC; CD135 ANTIGEN; DNA METHYLTRANSFERASE 3A; QUIZARTINIB; RETINOIC ACID; SORAFENIB; SUNITINIB; WT1 PROTEIN; NUCLEOTIDE;

EID: 84907997640     PISSN: 00371963     EISSN: 15328686     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2014.08.004     Document Type: Article
Times cited : (18)

References (91)
  • 1
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell P.C. The clonal evolution of tumor cell populations. Science 1976, 194:23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 3
    • 0029066836 scopus 로고
    • Change in karyotype between diagnosis and first relapse in acute myelogenous leukemia
    • Estey E., Keating M.J., Pierce S., Stass S. Change in karyotype between diagnosis and first relapse in acute myelogenous leukemia. Leukemia 1995, 9:972-976.
    • (1995) Leukemia , vol.9 , pp. 972-976
    • Estey, E.1    Keating, M.J.2    Pierce, S.3    Stass, S.4
  • 4
    • 0024401553 scopus 로고
    • Cytogenetic studies of 103 patients with acute myelogenous leukemia in relapse
    • Garson O.M., Hagemeijer A., Sakurai M., et al. Cytogenetic studies of 103 patients with acute myelogenous leukemia in relapse. Cancer Genet Cytogenet 1989, 40:187-202.
    • (1989) Cancer Genet Cytogenet , vol.40 , pp. 187-202
    • Garson, O.M.1    Hagemeijer, A.2    Sakurai, M.3
  • 5
    • 0036798512 scopus 로고    scopus 로고
    • Karyotype instability between diagnosis and relapse in 117 patients with acute myeloid leukemia: implications for resistance against therapy
    • Kern W., Haferlach T., Schnittger S., et al. Karyotype instability between diagnosis and relapse in 117 patients with acute myeloid leukemia: implications for resistance against therapy. Leukemia 2002, 16:2084-2091.
    • (2002) Leukemia , vol.16 , pp. 2084-2091
    • Kern, W.1    Haferlach, T.2    Schnittger, S.3
  • 6
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M., Maley C.C. Clonal evolution in cancer. Nature 2012, 481:306-313.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 7
    • 0034661150 scopus 로고    scopus 로고
    • Apparently unrelated clones shown by spectral karyotyping to represent clonal evolution of cryptic t(10;11)(p13;q23) in a patient with acute monoblastic leukemia
    • Stark B., Jeison M., Gobuzov R., et al. Apparently unrelated clones shown by spectral karyotyping to represent clonal evolution of cryptic t(10;11)(p13;q23) in a patient with acute monoblastic leukemia. Cancer Genet Cytogenet 2000, 120:105-110.
    • (2000) Cancer Genet Cytogenet , vol.120 , pp. 105-110
    • Stark, B.1    Jeison, M.2    Gobuzov, R.3
  • 8
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson K., Lutz C., van Delft F.W., et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011, 469:356-361.
    • (2011) Nature , vol.469 , pp. 356-361
    • Anderson, K.1    Lutz, C.2    van Delft, F.W.3
  • 9
    • 0027730783 scopus 로고
    • Acute myeloid leukemia (AML) can be oligoclonal
    • Schmetzer H.M., Gerhartz H.H. Acute myeloid leukemia (AML) can be oligoclonal. Leukemia 1993, 7:1965-1970.
    • (1993) Leukemia , vol.7 , pp. 1965-1970
    • Schmetzer, H.M.1    Gerhartz, H.H.2
  • 10
    • 0032831614 scopus 로고    scopus 로고
    • Evaluation of clonality in myeloid stem-cell disorders
    • Gale R.E. Evaluation of clonality in myeloid stem-cell disorders. Semin Hematol 1999, 36:361-372.
    • (1999) Semin Hematol , vol.36 , pp. 361-372
    • Gale, R.E.1
  • 11
    • 0029090558 scopus 로고
    • Single or multistep origin of hemopoietic tumors: the contribution of clonality studies
    • Lo Coco F., Saglio G. Single or multistep origin of hemopoietic tumors: the contribution of clonality studies. Leukemia 1995, 9:1586-1589.
    • (1995) Leukemia , vol.9 , pp. 1586-1589
    • Lo Coco, F.1    Saglio, G.2
  • 12
    • 84864255882 scopus 로고    scopus 로고
    • The origin and evolution of mutations in acute myeloid leukemia
    • Welch J.S., Ley T.J., Link D.C., et al. The origin and evolution of mutations in acute myeloid leukemia. Cell 2012, 150:1-15.
    • (2012) Cell , vol.150 , pp. 1-15
    • Welch, J.S.1    Ley, T.J.2    Link, D.C.3
  • 13
    • 84865827060 scopus 로고    scopus 로고
    • Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
    • 149ra118
    • Jan M., Snyder T.M., Corces-Zimmerman M.R., et al. Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med 2012, 4:149ra118.
    • (2012) Sci Transl Med , vol.4
    • Jan, M.1    Snyder, T.M.2    Corces-Zimmerman, M.R.3
  • 15
    • 37449023112 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease in acute myeloid leukemia
    • Kern W., Haferlach C., Haferlach T., Schnittger S. Monitoring of minimal residual disease in acute myeloid leukemia. Cancer 2008, 112:4-16.
    • (2008) Cancer , vol.112 , pp. 4-16
    • Kern, W.1    Haferlach, C.2    Haferlach, T.3    Schnittger, S.4
  • 16
    • 0021345113 scopus 로고
    • Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
    • Larson R.A., Kondo K., Vardiman J.W., et al. Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med 1984, 76:827-841.
    • (1984) Am J Med , vol.76 , pp. 827-841
    • Larson, R.A.1    Kondo, K.2    Vardiman, J.W.3
  • 17
    • 84907981950 scopus 로고    scopus 로고
    • Comparison of mutation patterns between diagnosis and relapse in 444 patients with acute myeloid leukemia shows high variability of stability and influence on time to relapse
    • Schnittger S., Alpermann T., Nadarajah N., et al. Comparison of mutation patterns between diagnosis and relapse in 444 patients with acute myeloid leukemia shows high variability of stability and influence on time to relapse. American Society of Hematology 2012, December 8-11, (Atlanta, Ga).
    • American Society of Hematology
    • Schnittger, S.1    Alpermann, T.2    Nadarajah, N.3
  • 18
    • 0347480534 scopus 로고    scopus 로고
    • Recurrence of acute myelogenous leukemia with the same AML1/ETO breakpoint as at diagnosis after complete remission lasting 15 years: analysis of stored bone marrow smears
    • Tsukamoto N., Karasawa M., Tanaka Y., et al. Recurrence of acute myelogenous leukemia with the same AML1/ETO breakpoint as at diagnosis after complete remission lasting 15 years: analysis of stored bone marrow smears. Int J Hematol 2003, 78:362-369.
    • (2003) Int J Hematol , vol.78 , pp. 362-369
    • Tsukamoto, N.1    Karasawa, M.2    Tanaka, Y.3
  • 19
    • 0034494569 scopus 로고    scopus 로고
    • Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 Trial
    • De Botton S., Chevret S., Sanz M., et al. Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 Trial. Br J Haematol 2000, 111:801-806.
    • (2000) Br J Haematol , vol.111 , pp. 801-806
    • De Botton, S.1    Chevret, S.2    Sanz, M.3
  • 20
    • 0029835098 scopus 로고    scopus 로고
    • Incidence and implication of additional chromosome aberrations in acute promyelocytic leukaemia with translocation t(15;17)(q22;q21): a report on 50 patients
    • Schoch C., Haase D., Haferlach T., et al. Incidence and implication of additional chromosome aberrations in acute promyelocytic leukaemia with translocation t(15;17)(q22;q21): a report on 50 patients. Br J Haematol 1996, 94:493-500.
    • (1996) Br J Haematol , vol.94 , pp. 493-500
    • Schoch, C.1    Haase, D.2    Haferlach, T.3
  • 21
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children[U+05F3]s Leukaemia Working Parties
    • Grimwade D., Walker H., Oliver F., et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children[U+05F3]s Leukaemia Working Parties. Blood 1998, 92:2322-2333.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 22
    • 0025918683 scopus 로고
    • Cytogenetic studies in acute promyelocytic leukemia: a survey of secondary chromosomal abnormalities
    • Berger R., Le Coniat M., Derre J., et al. Cytogenetic studies in acute promyelocytic leukemia: a survey of secondary chromosomal abnormalities. Genes Chromosomes Cancer 1991, 3:332-337.
    • (1991) Genes Chromosomes Cancer , vol.3 , pp. 332-337
    • Berger, R.1    Le Coniat, M.2    Derre, J.3
  • 23
    • 0037438881 scopus 로고    scopus 로고
    • Trisomy 21 and other chromosomal abnormalities in acute promyelocytic leukemia
    • Wan T.S., Ma S.K., Au W.Y., et al. Trisomy 21 and other chromosomal abnormalities in acute promyelocytic leukemia. Cancer Genet Cytogenet 2003, 140:170-173.
    • (2003) Cancer Genet Cytogenet , vol.140 , pp. 170-173
    • Wan, T.S.1    Ma, S.K.2    Au, W.Y.3
  • 24
    • 0030872469 scopus 로고    scopus 로고
    • High frequency of trisomy 8 in acute promyelocytic leukemia: a fluorescence in situ hybridization study
    • Sessarego M., Fugazza G., Balleari E., et al. High frequency of trisomy 8 in acute promyelocytic leukemia: a fluorescence in situ hybridization study. Cancer Genet Cytogenet 1997, 97:161-164.
    • (1997) Cancer Genet Cytogenet , vol.97 , pp. 161-164
    • Sessarego, M.1    Fugazza, G.2    Balleari, E.3
  • 25
    • 0033763906 scopus 로고    scopus 로고
    • Additional chromosome aberrations in acute promyelocytic leukemia: characteristics and prognostic influence
    • Pantic M., Novak A., Marisavljevic D., et al. Additional chromosome aberrations in acute promyelocytic leukemia: characteristics and prognostic influence. Med Oncol 2000, 17:307-313.
    • (2000) Med Oncol , vol.17 , pp. 307-313
    • Pantic, M.1    Novak, A.2    Marisavljevic, D.3
  • 26
    • 0029079231 scopus 로고
    • Trisomy 8 in acute promyelocytic leukaemia: an interphase study by fluorescence in situ hybridization
    • Kwong Y.L., Wong K.F., Chan T.K. Trisomy 8 in acute promyelocytic leukaemia: an interphase study by fluorescence in situ hybridization. Br J Haematol 1995, 90:697-700.
    • (1995) Br J Haematol , vol.90 , pp. 697-700
    • Kwong, Y.L.1    Wong, K.F.2    Chan, T.K.3
  • 27
    • 0031040058 scopus 로고    scopus 로고
    • Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia
    • Hiorns L.R., Swansbury G.J., Mehta J., et al. Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia. Br J Haematol 1997, 96:314-321.
    • (1997) Br J Haematol , vol.96 , pp. 314-321
    • Hiorns, L.R.1    Swansbury, G.J.2    Mehta, J.3
  • 28
    • 84872056078 scopus 로고    scopus 로고
    • Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG)
    • Paschka P., Du J., Schlenk R.F., et al. Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG). Blood 2013, 121:170-177.
    • (2013) Blood , vol.121 , pp. 170-177
    • Paschka, P.1    Du, J.2    Schlenk, R.F.3
  • 29
    • 75149119465 scopus 로고    scopus 로고
    • Modeling interactions between leukemia-specific chromosomal changes, somatic mutations, and gene expression patterns during progression of core-binding factor leukemias
    • Jones D., Yao H., Romans A., et al. Modeling interactions between leukemia-specific chromosomal changes, somatic mutations, and gene expression patterns during progression of core-binding factor leukemias. Genes Chromosomes Cancer 2010, 49:182-191.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 182-191
    • Jones, D.1    Yao, H.2    Romans, A.3
  • 30
    • 80052493235 scopus 로고    scopus 로고
    • Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia
    • Wakita S., Yamaguchi H., Miyake K., et al. Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia. Leukemia 2010, 25:1423-1432.
    • (2010) Leukemia , vol.25 , pp. 1423-1432
    • Wakita, S.1    Yamaguchi, H.2    Miyake, K.3
  • 31
    • 84883742457 scopus 로고    scopus 로고
    • The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia
    • Allen C., Hills R.K., Lamb K., et al. The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia. Leukemia 2013, 27:1891-1901.
    • (2013) Leukemia , vol.27 , pp. 1891-1901
    • Allen, C.1    Hills, R.K.2    Lamb, K.3
  • 32
    • 34547844402 scopus 로고    scopus 로고
    • The incidence and prognostic significance of additional chromosome restructuring in acute promyelocytic leukemia
    • Olshanskaya Y.V., Gutorova D.S., Shuravina E.N., et al. The incidence and prognostic significance of additional chromosome restructuring in acute promyelocytic leukemia. Gematologiya I Transfuziologiya 2007, 52:27-32.
    • (2007) Gematologiya I Transfuziologiya , vol.52 , pp. 27-32
    • Olshanskaya, Y.V.1    Gutorova, D.S.2    Shuravina, E.N.3
  • 33
    • 0030912485 scopus 로고    scopus 로고
    • Secondary cytogenetic changes in acute promyelocytic leukemia-prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study
    • Slack J.L., Arthur D.C., Lawrence D., et al. Secondary cytogenetic changes in acute promyelocytic leukemia-prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study. J Clin Oncol 1997, 15:1786-1795.
    • (1997) J Clin Oncol , vol.15 , pp. 1786-1795
    • Slack, J.L.1    Arthur, D.C.2    Lawrence, D.3
  • 34
    • 0034855778 scopus 로고    scopus 로고
    • Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anthracyclin based protocol
    • Hernandez J.M., Martin G., Gutierrez N.C., et al. Additional cytogenetic changes do not influence the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with an ATRA plus anthracyclin based protocol. A report of the Spanish group PETHEMA. Haematologica 2001, 86:807-813.
    • (2001) A report of the Spanish group PETHEMA. Haematologica , vol.86 , pp. 807-813
    • Hernandez, J.M.1    Martin, G.2    Gutierrez, N.C.3
  • 35
    • 48749106371 scopus 로고    scopus 로고
    • Acute myeloid leukemia harboring t(8;21)(q22;q22): a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations
    • Lin P., Chen L., Luthra R., et al. Acute myeloid leukemia harboring t(8;21)(q22;q22): a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations. Mod Pathol 2008, 21:1029-1036.
    • (2008) Mod Pathol , vol.21 , pp. 1029-1036
    • Lin, P.1    Chen, L.2    Luthra, R.3
  • 36
    • 20244386716 scopus 로고    scopus 로고
    • Del (9q) AML: clinical and cytological characteristics and prognostic implications
    • Peniket A., Wainscoat J., Side L., et al. Del (9q) AML: clinical and cytological characteristics and prognostic implications. Br J Haematol 2005, 129:210-220.
    • (2005) Br J Haematol , vol.129 , pp. 210-220
    • Peniket, A.1    Wainscoat, J.2    Side, L.3
  • 37
    • 79951966910 scopus 로고    scopus 로고
    • Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations
    • Bacher U., Haferlach T., Alpermann T., et al. Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations. Br J Haematol 2011, 152:713-720.
    • (2011) Br J Haematol , vol.152 , pp. 713-720
    • Bacher, U.1    Haferlach, T.2    Alpermann, T.3
  • 38
    • 0024523546 scopus 로고
    • Two karyotypically independent leukemic clones with the t(8;21) and 11q23 translocation in acute myeloblastic leukemia at relapse
    • Hayashi Y., Raimondi S.C., Behm F.G., et al. Two karyotypically independent leukemic clones with the t(8;21) and 11q23 translocation in acute myeloblastic leukemia at relapse. Blood 1989, 73:1650-1655.
    • (1989) Blood , vol.73 , pp. 1650-1655
    • Hayashi, Y.1    Raimondi, S.C.2    Behm, F.G.3
  • 39
    • 39149094274 scopus 로고    scopus 로고
    • Emergence of an unrelated highly aberrant clone in an AML patient at relapse four months after peripheral blood stem cell transplantation
    • Kadam P.S., Jain H.V., Parikh P.M., et al. Emergence of an unrelated highly aberrant clone in an AML patient at relapse four months after peripheral blood stem cell transplantation. Indian J Hum Genet 2007, 13:114-118.
    • (2007) Indian J Hum Genet , vol.13 , pp. 114-118
    • Kadam, P.S.1    Jain, H.V.2    Parikh, P.M.3
  • 40
    • 84907981949 scopus 로고    scopus 로고
    • Composite single cell genetics and clonal phylogeny in acute lymphoblastic leukaemia
    • (Atlanta, Ga)
    • Potter N.E., Ermini L., Papaemmanuil E., et al. Composite single cell genetics and clonal phylogeny in acute lymphoblastic leukaemia. American Society of Hematology 2012, (Atlanta, Ga).
    • (2012) American Society of Hematology
    • Potter, N.E.1    Ermini, L.2    Papaemmanuil, E.3
  • 41
    • 0033043084 scopus 로고    scopus 로고
    • Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene
    • Nakano Y., Kiyoi H., Miyawaki S., et al. Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene. Br J Haematol 1999, 104:659-664.
    • (1999) Br J Haematol , vol.104 , pp. 659-664
    • Nakano, Y.1    Kiyoi, H.2    Miyawaki, S.3
  • 42
    • 84896081834 scopus 로고    scopus 로고
    • Functional heterogeneity of genetically defined subclones in acute myeloid leukemia
    • Klco J.M., Spencer D.H., Miller C.A., et al. Functional heterogeneity of genetically defined subclones in acute myeloid leukemia. Cancer Cell 2014, 25:379-392.
    • (2014) Cancer Cell , vol.25 , pp. 379-392
    • Klco, J.M.1    Spencer, D.H.2    Miller, C.A.3
  • 43
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • Shlush L.I., Zandi S., Mitchell A., et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 2014, 506:328-333.
    • (2014) Nature , vol.506 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3
  • 44
    • 84864775100 scopus 로고    scopus 로고
    • Diversity of the juxtamembrane and TKD1 mutations (exons 13-15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data
    • Schnittger S., Bacher U., Haferlach C., et al. Diversity of the juxtamembrane and TKD1 mutations (exons 13-15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data. Genes Chromosomes Cancer 2012, 51:910-924.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 910-924
    • Schnittger, S.1    Bacher, U.2    Haferlach, C.3
  • 45
    • 84873989514 scopus 로고    scopus 로고
    • Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR
    • Beierl K., Tseng L.H., Beierl R., et al. Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR. Diagn Mol Pathol 2013, 22:1-9.
    • (2013) Diagn Mol Pathol , vol.22 , pp. 1-9
    • Beierl, K.1    Tseng, L.H.2    Beierl, R.3
  • 46
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley T.J., Ding L., Walter M.J., et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010, 363:2424-2433.
    • (2010) N Engl J Med , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 47
    • 84862654187 scopus 로고    scopus 로고
    • Detection of high-frequency and novel DNMT3A mutations in acute myeloid leukemia by high-resolution melting curve analysis
    • Singh R.R., Bains A., Patel K.P., et al. Detection of high-frequency and novel DNMT3A mutations in acute myeloid leukemia by high-resolution melting curve analysis. J Mol Diagn 2012, 14:336-345.
    • (2012) J Mol Diagn , vol.14 , pp. 336-345
    • Singh, R.R.1    Bains, A.2    Patel, K.P.3
  • 48
    • 84894468522 scopus 로고    scopus 로고
    • DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia
    • Bisling K.E., Brewin J.N., McGovern A.P., et al. DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia. Leuk Lymphoma 2014, 55:711-714.
    • (2014) Leuk Lymphoma , vol.55 , pp. 711-714
    • Bisling, K.E.1    Brewin, J.N.2    McGovern, A.P.3
  • 49
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research N
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013, 368:2059-2074. Cancer Genome Atlas Research N.
    • (2013) N Engl J Med , vol.368 , pp. 2059-2074
  • 50
    • 80054047835 scopus 로고    scopus 로고
    • NPM1 mutation is a stable marker for minimal residual disease monitoring in acute myeloid leukaemia patients with increased sensitivity compared to WT1 expression
    • Kristensen T., Moller M.B., Friis L., et al. NPM1 mutation is a stable marker for minimal residual disease monitoring in acute myeloid leukaemia patients with increased sensitivity compared to WT1 expression. Eur J Haematol 2011, 87:400-408.
    • (2011) Eur J Haematol , vol.87 , pp. 400-408
    • Kristensen, T.1    Moller, M.B.2    Friis, L.3
  • 51
    • 27744502042 scopus 로고    scopus 로고
    • Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype
    • Boissel N., Renneville A., Biggio V., et al. Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype. Blood 2005, 106:3618-3620.
    • (2005) Blood , vol.106 , pp. 3618-3620
    • Boissel, N.1    Renneville, A.2    Biggio, V.3
  • 52
    • 24144494881 scopus 로고    scopus 로고
    • Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia
    • Suzuki T., Kiyoi H., Ozeki K., et al. Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood 2005, 106:2854-2861.
    • (2005) Blood , vol.106 , pp. 2854-2861
    • Suzuki, T.1    Kiyoi, H.2    Ozeki, K.3
  • 53
    • 84862012956 scopus 로고    scopus 로고
    • The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse
    • Bachas C., Schuurhuis G.J., Assaraf Y.G., et al. The role of minor subpopulations within the leukemic blast compartment of AML patients at initial diagnosis in the development of relapse. Leukemia 2012, 26:1313-1320.
    • (2012) Leukemia , vol.26 , pp. 1313-1320
    • Bachas, C.1    Schuurhuis, G.J.2    Assaraf, Y.G.3
  • 54
    • 3843149406 scopus 로고    scopus 로고
    • Evolution of FLT3-ITD and D835 activating point mutations in relapsing acute myeloid leukemia and response to salvage therapy
    • Tiesmeier J., Muller-Tidow C., Westermann A., et al. Evolution of FLT3-ITD and D835 activating point mutations in relapsing acute myeloid leukemia and response to salvage therapy. Leuk Res 2004, 28:1069-1074.
    • (2004) Leuk Res , vol.28 , pp. 1069-1074
    • Tiesmeier, J.1    Muller-Tidow, C.2    Westermann, A.3
  • 55
    • 84877587361 scopus 로고    scopus 로고
    • Mutations of the epigenetics-modifying gene (DNMT3a, TET2, IDH1/2) at diagnosis may induce FLT3-ITD at relapse in de novo acute myeloid leukemia
    • Wakita S., Yamaguchi H., Omori I., et al. Mutations of the epigenetics-modifying gene (DNMT3a, TET2, IDH1/2) at diagnosis may induce FLT3-ITD at relapse in de novo acute myeloid leukemia. Leukemia 2012, 27:1044-1052.
    • (2012) Leukemia , vol.27 , pp. 1044-1052
    • Wakita, S.1    Yamaguchi, H.2    Omori, I.3
  • 56
    • 84862909358 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications
    • Hou H.A., Kuo Y.Y., Liu C.Y., et al. DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications. Blood 2012, 119:559-568.
    • (2012) Blood , vol.119 , pp. 559-568
    • Hou, H.A.1    Kuo, Y.Y.2    Liu, C.Y.3
  • 57
    • 77955364207 scopus 로고    scopus 로고
    • FLT3 mutations at diagnosis and relapse in acute myeloid leukemia: cytogenetic and pathologic correlations, including cuplike blast morphology
    • McCormick S.R., McCormick M.J., Grutkoski P.S., et al. FLT3 mutations at diagnosis and relapse in acute myeloid leukemia: cytogenetic and pathologic correlations, including cuplike blast morphology. Arch Pathol Lab Med 2010, 134:1143-1151.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 1143-1151
    • McCormick, S.R.1    McCormick, M.J.2    Grutkoski, P.S.3
  • 58
    • 84864739408 scopus 로고    scopus 로고
    • Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia
    • Nazha A., Cortes J., Faderl S., et al. Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia. Haematologica 2012, 97:1242-1245.
    • (2012) Haematologica , vol.97 , pp. 1242-1245
    • Nazha, A.1    Cortes, J.2    Faderl, S.3
  • 59
    • 77957078727 scopus 로고    scopus 로고
    • Genomic, immunophenotypic, and NPM1/FLT3 mutational studies on 17 patients with normal karyotype acute myeloid leukemia (AML) followed by aberrant karyotype AML at relapse
    • Wang E.S., Sait S.N., Gold D., et al. Genomic, immunophenotypic, and NPM1/FLT3 mutational studies on 17 patients with normal karyotype acute myeloid leukemia (AML) followed by aberrant karyotype AML at relapse. Cancer Genet Cytogenet 2010, 202:101-107.
    • (2010) Cancer Genet Cytogenet , vol.202 , pp. 101-107
    • Wang, E.S.1    Sait, S.N.2    Gold, D.3
  • 60
    • 77954671159 scopus 로고    scopus 로고
    • WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system
    • Hou H.A., Huang T.C., Lin L.I., et al. WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system. Blood 2010, 115:5222-5231.
    • (2010) Blood , vol.115 , pp. 5222-5231
    • Hou, H.A.1    Huang, T.C.2    Lin, L.I.3
  • 61
    • 79751530369 scopus 로고    scopus 로고
    • The prognostic impact and stability of isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia
    • Chou W.C., Lei W.C., Ko B.S., et al. The prognostic impact and stability of isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia. Leukemia 2011, 25:246-253.
    • (2011) Leukemia , vol.25 , pp. 246-253
    • Chou, W.C.1    Lei, W.C.2    Ko, B.S.3
  • 62
    • 70349579540 scopus 로고    scopus 로고
    • Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML
    • Schnittger S., Kern W., Tschulik C., et al. Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML. Blood 2009, 114:2220-2231.
    • (2009) Blood , vol.114 , pp. 2220-2231
    • Schnittger, S.1    Kern, W.2    Tschulik, C.3
  • 63
    • 78649502291 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease in acute myeloid leukemia with frequent and rare patient-specific NPM1 mutations
    • Dvorakova D., Racil Z., Jeziskova I., et al. Monitoring of minimal residual disease in acute myeloid leukemia with frequent and rare patient-specific NPM1 mutations. Am J Hematol 2010, 85:926-929.
    • (2010) Am J Hematol , vol.85 , pp. 926-929
    • Dvorakova, D.1    Racil, Z.2    Jeziskova, I.3
  • 64
    • 84901335895 scopus 로고    scopus 로고
    • Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse
    • Jain P., Kantarjian H., Patel K., et al. Mutated NPM1 in patients with acute myeloid leukemia in remission and relapse. Leuk Lymphoma 2014, 55:1337-1344.
    • (2014) Leuk Lymphoma , vol.55 , pp. 1337-1344
    • Jain, P.1    Kantarjian, H.2    Patel, K.3
  • 65
    • 0024520075 scopus 로고
    • Acute myeloid leukemia: analysis of ras gene mutations and clonality defined by polymorphic X-linked loci
    • Bartram C.R., Ludwig W.D., Hiddemann W., et al. Acute myeloid leukemia: analysis of ras gene mutations and clonality defined by polymorphic X-linked loci. Leukemia 1989, 3:247-256.
    • (1989) Leukemia , vol.3 , pp. 247-256
    • Bartram, C.R.1    Ludwig, W.D.2    Hiddemann, W.3
  • 66
    • 0036785393 scopus 로고    scopus 로고
    • Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
    • Kottaridis P.D., Gale R.E., Langabeer S.E., Frew M.E., Bowen D.T., Linch D.C. Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors. Blood 2002, 100:2393-2398.
    • (2002) Blood , vol.100 , pp. 2393-2398
    • Kottaridis, P.D.1    Gale, R.E.2    Langabeer, S.E.3    Frew, M.E.4    Bowen, D.T.5    Linch, D.C.6
  • 67
    • 4544243925 scopus 로고    scopus 로고
    • Abnormalities of p51, p53, FLT3 and N-ras genes and their prognostic value in relapsed acute myeloid leukemia
    • Nakamura H., Inokuchi K., Yamaguchi H., Dan K. Abnormalities of p51, p53, FLT3 and N-ras genes and their prognostic value in relapsed acute myeloid leukemia. J Nippon Med Sch 2004, 71:270-278.
    • (2004) J Nippon Med Sch , vol.71 , pp. 270-278
    • Nakamura, H.1    Inokuchi, K.2    Yamaguchi, H.3    Dan, K.4
  • 68
    • 39149092043 scopus 로고    scopus 로고
    • Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples
    • Shih L.Y., Liang D.C., Huang C.F., et al. Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples. Leukemia 2008, 22:303-307.
    • (2008) Leukemia , vol.22 , pp. 303-307
    • Shih, L.Y.1    Liang, D.C.2    Huang, C.F.3
  • 69
    • 33646474281 scopus 로고    scopus 로고
    • AML patients with CEBPalpha mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples
    • Shih L.Y., Liang D.C., Huang C.F., et al. AML patients with CEBPalpha mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples. Leukemia 2006, 20:604-609.
    • (2006) Leukemia , vol.20 , pp. 604-609
    • Shih, L.Y.1    Liang, D.C.2    Huang, C.F.3
  • 70
    • 84876798097 scopus 로고    scopus 로고
    • Identification of emerging FLT3 ITD-positive clones during clinical remission and kinetics of disease relapse in acute myeloid leukaemia with mutated nucleophosmin
    • Ottone T., Zaza S., Divona M., et al. Identification of emerging FLT3 ITD-positive clones during clinical remission and kinetics of disease relapse in acute myeloid leukaemia with mutated nucleophosmin. Br J Haematol 2013, 161:533-540.
    • (2013) Br J Haematol , vol.161 , pp. 533-540
    • Ottone, T.1    Zaza, S.2    Divona, M.3
  • 71
    • 84855967858 scopus 로고    scopus 로고
    • Minimal residual disease monitoring based on FLT3 internal tandem duplication in adult acute myeloid leukemia
    • Abdelhamid E., Preudhomme C., Helevaut N., et al. Minimal residual disease monitoring based on FLT3 internal tandem duplication in adult acute myeloid leukemia. Leuk Res 2012, 36:316-323.
    • (2012) Leuk Res , vol.36 , pp. 316-323
    • Abdelhamid, E.1    Preudhomme, C.2    Helevaut, N.3
  • 72
    • 84883730914 scopus 로고    scopus 로고
    • Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia
    • Krönke J., Bullinger L., Teleanu V., et al. Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia. Blood 2013, 122:100-108.
    • (2013) Blood , vol.122 , pp. 100-108
    • Krönke, J.1    Bullinger, L.2    Teleanu, V.3
  • 73
    • 33745198953 scopus 로고    scopus 로고
    • Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples
    • Cloos J., Goemans B.F., Hess C.J., et al. Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples. Leukemia 2006, 20:1217-1220.
    • (2006) Leukemia , vol.20 , pp. 1217-1220
    • Cloos, J.1    Goemans, B.F.2    Hess, C.J.3
  • 74
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukemia revealed by whole-genome sequencing
    • Ding L., Ley T.J., Larson D.E., et al. Clonal evolution in relapsed acute myeloid leukemia revealed by whole-genome sequencing. Nature 2012, 481:506-510.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3
  • 75
    • 84863337617 scopus 로고    scopus 로고
    • Clonal architecture of secondary acute myeloid leukemia
    • Walter M.J., Shen D., Ding L., et al. Clonal architecture of secondary acute myeloid leukemia. N Engl J Med 2012, 366:1090-1098.
    • (2012) N Engl J Med , vol.366 , pp. 1090-1098
    • Walter, M.J.1    Shen, D.2    Ding, L.3
  • 76
    • 84892582245 scopus 로고    scopus 로고
    • Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations
    • Lin T.L., Nagata Y., Kao H.W., et al. Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations. Haematologica 2014, 99:28-36.
    • (2014) Haematologica , vol.99 , pp. 28-36
    • Lin, T.L.1    Nagata, Y.2    Kao, H.W.3
  • 77
    • 84894304555 scopus 로고    scopus 로고
    • Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    • Corces-Zimmerman M.R., Hong W.J., Weissman I.L., Medeiros B.C., Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A 2014, 111:2548-2553.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 2548-2553
    • Corces-Zimmerman, M.R.1    Hong, W.J.2    Weissman, I.L.3    Medeiros, B.C.4    Majeti, R.5
  • 78
    • 0029901946 scopus 로고    scopus 로고
    • Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age
    • Busque L., Mio R., Mattioli J., et al. Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age. Blood 1996, 88:59-65.
    • (1996) Blood , vol.88 , pp. 59-65
    • Busque, L.1    Mio, R.2    Mattioli, J.3
  • 79
    • 0030928170 scopus 로고    scopus 로고
    • Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age
    • Gale R.E., Fielding A.K., Harrison C.N., Linch D.C. Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age. Br J Haematol 1997, 98:512-519.
    • (1997) Br J Haematol , vol.98 , pp. 512-519
    • Gale, R.E.1    Fielding, A.K.2    Harrison, C.N.3    Linch, D.C.4
  • 80
    • 84861591789 scopus 로고    scopus 로고
    • Detectable clonal mosaicism from birth to old age and its relationship to cancer
    • Laurie C.C., Laurie C.A., Rice K., et al. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet 2012, 44:642-650.
    • (2012) Nat Genet , vol.44 , pp. 642-650
    • Laurie, C.C.1    Laurie, C.A.2    Rice, K.3
  • 81
    • 84868208186 scopus 로고    scopus 로고
    • Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
    • Busque L., Patel J.P., Figueroa M.E., et al. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet 2012, 44:1179-1181.
    • (2012) Nat Genet , vol.44 , pp. 1179-1181
    • Busque, L.1    Patel, J.P.2    Figueroa, M.E.3
  • 82
    • 0028081190 scopus 로고
    • Sequential acquisition of trisomy 8 and N-ras mutation in acute myeloid leukaemia demonstrated by analysis of isolated leukaemic colonies
    • Price C.M., Marshall C.J., Bashey A. Sequential acquisition of trisomy 8 and N-ras mutation in acute myeloid leukaemia demonstrated by analysis of isolated leukaemic colonies. Br J Haematol 1994, 88:338-342.
    • (1994) Br J Haematol , vol.88 , pp. 338-342
    • Price, C.M.1    Marshall, C.J.2    Bashey, A.3
  • 83
    • 84902685635 scopus 로고    scopus 로고
    • Single cell analysis exposes intra-tumor heterogeneity and suggests that FLT3-ITD is a late event in leukemogenesis
    • Shouval R., Shlush L.I., Yehudai-Resheff S., et al. Single cell analysis exposes intra-tumor heterogeneity and suggests that FLT3-ITD is a late event in leukemogenesis. Exp Hematol 2014, 42:457-463.
    • (2014) Exp Hematol , vol.42 , pp. 457-463
    • Shouval, R.1    Shlush, L.I.2    Yehudai-Resheff, S.3
  • 84
    • 77949887020 scopus 로고    scopus 로고
    • FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML
    • Pratz K.W., Sato T., Murphy K.M., et al. FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. Blood 2010, 115:1425-1432.
    • (2010) Blood , vol.115 , pp. 1425-1432
    • Pratz, K.W.1    Sato, T.2    Murphy, K.M.3
  • 85
    • 84860747223 scopus 로고    scopus 로고
    • Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
    • Smith C.C., Wang Q., Chin C.S., et al. Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Nature 2012, 485:260-263.
    • (2012) Nature , vol.485 , pp. 260-263
    • Smith, C.C.1    Wang, Q.2    Chin, C.S.3
  • 86
    • 84863785488 scopus 로고    scopus 로고
    • Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns
    • Moore A.S., Faisal A., Gonzalez de Castro D., et al. Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns. Leukemia 2012, 26:1462-1470.
    • (2012) Leukemia , vol.26 , pp. 1462-1470
    • Moore, A.S.1    Faisal, A.2    Gonzalez de Castro, D.3
  • 87
    • 84886413213 scopus 로고    scopus 로고
    • Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia
    • Baker S.D., Zimmerman E.I., Wang Y.D., et al. Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia. Clin Cancer Res 2013, 19:5758-5768.
    • (2013) Clin Cancer Res , vol.19 , pp. 5758-5768
    • Baker, S.D.1    Zimmerman, E.I.2    Wang, Y.D.3
  • 88
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C., Steudel C., Mohr B., et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood 2002, 99:4326-4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 89
    • 27244453278 scopus 로고    scopus 로고
    • Acute myeloid leukaemia with FLT3 gene mutations of both internal tandem duplication and point mutation type
    • Chen W., Jones D., Medeiros L.J., Luthra R., Lin P. Acute myeloid leukaemia with FLT3 gene mutations of both internal tandem duplication and point mutation type. Br J Haematol 2005, 130:726-728.
    • (2005) Br J Haematol , vol.130 , pp. 726-728
    • Chen, W.1    Jones, D.2    Medeiros, L.J.3    Luthra, R.4    Lin, P.5
  • 90
    • 0242551845 scopus 로고    scopus 로고
    • FLT3 mutations are associated with other molecular lesions in AML
    • Carnicer M.J., Nomdedeu J.F., Lasa A., et al. FLT3 mutations are associated with other molecular lesions in AML. Leuk Res 2004, 28:19-23.
    • (2004) Leuk Res , vol.28 , pp. 19-23
    • Carnicer, M.J.1    Nomdedeu, J.F.2    Lasa, A.3
  • 91
    • 33750530369 scopus 로고    scopus 로고
    • Acute myeloid leukemia: epidemiology and etiology
    • Deschler B., Lubbert M. Acute myeloid leukemia: epidemiology and etiology. Cancer 2006, 107:2099-2107.
    • (2006) Cancer , vol.107 , pp. 2099-2107
    • Deschler, B.1    Lubbert, M.2


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