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Volumn 22, Issue 1, 2013, Pages 1-9

Detection of minor clones with internal tandem duplication mutations of FLT3 gene in acute myeloid leukemia using delta-PCR

Author keywords

acute myeloid leukemia; Delta PCR; FLT3; internal tandem duplication; minimal residual disease

Indexed keywords

ANTINEOPLASTIC AGENT; CD135 ANTIGEN;

EID: 84873989514     PISSN: 10529551     EISSN: 15334066     Source Type: Journal    
DOI: 10.1097/PDM.0b013e31825d81f4     Document Type: Article
Times cited : (11)

References (28)
  • 1
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature. 2001;411:355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 2
    • 0029998037 scopus 로고    scopus 로고
    • FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells
    • Turner AM, Lin NL, Issarachai S, et al. FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells. Blood. 1996;88:3383-3390.
    • (1996) Blood , vol.88 , pp. 3383-3390
    • Turner, A.M.1    Lin, N.L.2    Issarachai, S.3
  • 3
    • 0031686409 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
    • Kiyoi H, Towatari M, Yokota S, et al. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia. 1998;12: 1333-1337.
    • (1998) Leukemia , vol.12 , pp. 1333-1337
    • Kiyoi, H.1    Towatari, M.2    Yokota, S.3
  • 4
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom medical research council AML 10 and 12 trials
    • Kottaridis PD, Gale RE, Frew ME, et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood. 2001;98:1752-1759.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3
  • 5
    • 0035168677 scopus 로고    scopus 로고
    • Prevalence and prognostic significance of FLT3 internal tandem duplication in pediatric acute myeloid leukemia
    • Meshinchi S, Woods WG, Stirewalt DL, et al. Prevalence and prognostic significance of FLT3 internal tandem duplication in pediatric acute myeloid leukemia. Blood. 2001;97:89-94.
    • (2001) Blood , vol.97 , pp. 89-94
    • Meshinchi, S.1    Woods, W.G.2    Stirewalt, D.L.3
  • 6
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 2002;99:4326-4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3
  • 7
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics FAB subtype and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S, Schoch C, Dugas M, et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood. 2002;100:59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3
  • 8
    • 79952043438 scopus 로고    scopus 로고
    • FLT3 inhibitors: A story of the old and the new
    • Fathi A, Levis M. FLT3 inhibitors: a story of the old and the new. Curr Opin Hematol. 2011;18:71-76.
    • (2011) Curr Opin Hematol , vol.18 , pp. 71-76
    • Fathi, A.1    Levis, M.2
  • 9
    • 2642511275 scopus 로고    scopus 로고
    • FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia
    • Schnittger S, Schoch C, Kern W, et al. FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia. Acta Haematol. 2004;112:68-78.
    • (2004) Acta Haematol , vol.112 , pp. 68-78
    • Schnittger, S.1    Schoch, C.2    Kern, W.3
  • 10
    • 0034777536 scopus 로고    scopus 로고
    • Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific
    • Stirewalt DL, Willman CL, Radich JP, et al. Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific. Leuk Res. 2001;25:1085-1088.
    • (2001) Leuk Res , vol.25 , pp. 1085-1088
    • Stirewalt, D.L.1    Willman, C.L.2    Radich, J.P.3
  • 11
    • 0030451722 scopus 로고    scopus 로고
    • Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
    • Nakao M, Yokota S, Iwai T, et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia. 1996;10:1911-1918.
    • (1996) Leukemia , vol.10 , pp. 1911-1918
    • Nakao, M.1    Yokota, S.2    Iwai, T.3
  • 12
    • 0038365363 scopus 로고    scopus 로고
    • Detection of FLT3 internal tandem duplication and D835 mutations by a multiplex polymerase chain reaction and capillary electrophoresis assay
    • Murphy KM, Levis M, Hafez MJ, et al. Detection of FLT3 internal tandem duplication and D835 mutations by a multiplex polymerase chain reaction and capillary electrophoresis assay. J Mol Diagn. 2003;5:96-102.
    • (2003) J Mol Diagn , vol.5 , pp. 96-102
    • Murphy, K.M.1    Levis, M.2    Hafez, M.J.3
  • 13
    • 78651061501 scopus 로고    scopus 로고
    • D-PCR, a simple method to detect translocations and insertion/deletion mutations
    • Lin MT, Tseng LH, Rich RG, et al. D-PCR, a simple method to detect translocations and insertion/deletion mutations. J Mol Diagn. 2011;13:85-92.
    • (2011) J Mol Diagn , vol.13 , pp. 85-92
    • Lin, M.T.1    Tseng, L.H.2    Rich, R.G.3
  • 14
    • 0036786289 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: A comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse
    • Shih LY, Huang CF, Wu JH, et al. Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse. Blood. 2002;100:2387-2392.
    • (2002) Blood , vol.100 , pp. 2387-2392
    • Shih, L.Y.1    Huang, C.F.2    Wu, J.H.3
  • 15
    • 0023275274 scopus 로고
    • Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas
    • Weiss LM, Warnke RA, Sklar J, et al. Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas. N Engl J Med. 1987;317:1185-1189.
    • (1987) N Engl J Med , vol.317 , pp. 1185-1189
    • Weiss, L.M.1    Warnke, R.A.2    Sklar, J.3
  • 16
    • 0021270716 scopus 로고
    • Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation
    • Tsujimoto Y, Yunis J, Onorato-Showe L, et al. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science. 1984;224: 1403-1406.
    • (1984) Science , vol.224 , pp. 1403-1406
    • Tsujimoto, Y.1    Yunis, J.2    Onorato-Showe, L.3
  • 17
    • 16944365287 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
    • Yokota S, Kiyoi H, Nakao M, et al. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines. Leukemia. 1997;11:1605-1609.
    • (1997) Leukemia , vol.11 , pp. 1605-1609
    • Yokota, S.1    Kiyoi, H.2    Nakao, M.3
  • 18
    • 0036727413 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
    • Wechsler J, Greene M, McDevitt MA, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002;32:148-152.
    • (2002) Nat Genet , vol.32 , pp. 148-152
    • Wechsler, J.1    Greene, M.2    McDevitt, M.A.3
  • 19
    • 0029921478 scopus 로고    scopus 로고
    • Mutations in theWilms' tumor geneWT1 in leukemias
    • King-Underwood L, Renshaw J, Pritchard-Jones K. Mutations in theWilms' tumor geneWT1 in leukemias. Blood. 1996;87:2171-2179.
    • (1996) Blood , vol.87 , pp. 2171-2179
    • King-Underwood, L.1    Renshaw, J.2    Pritchard-Jones, K.3
  • 20
    • 36349015373 scopus 로고    scopus 로고
    • A molecular fraction collecting tool for the ABI 310 automated sequencer
    • Lin MT, Rich RG, Shipley RF, et al. A molecular fraction collecting tool for the ABI 310 automated sequencer. J Mol Diagn. 2007;9:598-603.
    • (2007) J Mol Diagn , vol.9 , pp. 598-603
    • Lin, M.T.1    Rich, R.G.2    Shipley, R.F.3
  • 21
    • 0035476264 scopus 로고    scopus 로고
    • Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
    • Whitman SP, Archer KJ, Feng L, et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Res. 2001;61:7233-7239.
    • (2001) Cancer Res , vol.61 , pp. 7233-7239
    • Whitman, S.P.1    Archer, K.J.2    Feng, L.3
  • 22
    • 33845254595 scopus 로고    scopus 로고
    • Clinical implications of FLT3 mutations in pediatric AML
    • Meshinchi S, Alonzo TA, Stirewalt DL, et al. Clinical implications of FLT3 mutations in pediatric AML. Blood. 2006;108:3654-3661.
    • (2006) Blood , vol.108 , pp. 3654-3661
    • Meshinchi, S.1    Alonzo, T.A.2    Stirewalt, D.L.3
  • 23
    • 33745628343 scopus 로고    scopus 로고
    • More on prognostic significance of FLT3/ITD size in acute myeloid leukemia (AML)
    • Kusec R, Jaksic O, Ostojic S, et al. More on prognostic significance of FLT3/ITD size in acute myeloid leukemia (AML). Blood. 2006;108:405-406.
    • (2006) Blood , vol.108 , pp. 405-406
    • Kusec, R.1    Jaksic, O.2    Ostojic, S.3
  • 24
    • 33646431111 scopus 로고    scopus 로고
    • Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia
    • Stirewalt DL, Kopecky KJ, Meshinchi S, et al. Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia. Blood. 2006;107:3724-3726.
    • (2006) Blood , vol.107 , pp. 3724-3726
    • Stirewalt, D.L.1    Kopecky, K.J.2    Meshinchi, S.3
  • 25
    • 46749104163 scopus 로고    scopus 로고
    • Structural and numerical variation of FLT3/ITD in pediatric AML
    • Meshinchi S, StirewaltDL, Alonzo TA, et al. Structural and numerical variation of FLT3/ITD in pediatric AML. Blood. 2008;111:4930-4933.
    • (2008) Blood , vol.111 , pp. 4930-4933
    • Meshinchi, S.1    Stirewaltdl Alonzo, T.A.2
  • 26
    • 77949466438 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the progression of myelodysplastic syndrome
    • Nolte F, Hofmann WK. Molecular mechanisms involved in the progression of myelodysplastic syndrome. Future Oncol. 2010;6:445-455.
    • (2010) Future Oncol , vol.6 , pp. 445-455
    • Nolte, F.1    Hofmann, W.K.2
  • 27
    • 79251500335 scopus 로고    scopus 로고
    • FLT3 and NPM1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia
    • Bains A, Luthra R, Medeiros LJ, et al. FLT3 and NPM1 mutations in myelodysplastic syndromes: frequency and potential value for predicting progression to acute myeloid leukemia. Am J Clin Pathol. 2011;135:62-69.
    • (2011) Am J Clin Pathol , vol.135 , pp. 62-69
    • Bains, A.1    Luthra, R.2    Medeiros, L.J.3
  • 28
    • 70350504884 scopus 로고    scopus 로고
    • Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome
    • Kayser S, Schlenk RF, Londono MC, et al. Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome. Blood. 2009;114:2386-2392.
    • (2009) Blood , vol.114 , pp. 2386-2392
    • Kayser, S.1    Schlenk, R.F.2    Londono, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.