Rationally designed macrocyclic peptides as synergistic agonists of LPS-induced inflammatory response

Tetrahedron

Volumn 70, Issue 42, 2014, Pages 7664-7668

  Gao, Meng ^a   London, Nir ^b,d   Cheng, Kui ^c   Tamura, Ryo ^c   Jin, Jialin ^a   Schueler Furman, Ora ^b   Yin, Hang ^a,c  

^a TSINGHUA UNIVERSITY   (China)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Computational design; Drug synergy; Macrocyclic peptide; Myeloid differentiation factor 2; Toll like receptor 4

Indexed keywords

ALKALINE PHOSPHATASE; CYCLOPEPTIDE; CYSTEINE; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 2 MACROCYCLIC PEPTIDE; NITRIC OXIDE; SECRETED EMBRYONIC ALKALINE PHOSPHATASE; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; ARTICLE; CELL VIABILITY ASSAY; CRYSTAL STRUCTURE; CYCLIZATION; ELECTROSPRAY; INNATE IMMUNITY; MACROPHAGE; MASS SPECTROMETRY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MTT ASSAY; PEPTIDE SYNTHESIS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 84907940003     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2014.07.026     Document Type: Article

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