In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs

Journal of Medicinal Chemistry

Volumn 57, Issue 19, 2014, Pages 7999-8009

  Wang, Changning ^a   Schroeder, Frederick A ^a   Wey, Hsiao Ying ^a   Borra, Ronald ^a   Wagner, Florence F ^b   Reis, Surya ^a   Kim, Sung Won ^c   Holson, Edward B ^b   Haggarty, Stephen J ^a   Hooker, Jacob M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 11; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; MARTINOSTAT C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BABOON; BRAIN; CENTRAL NERVOUS SYSTEM; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG SYNTHESIS; EPIGENETICS; EX VIVO STUDY; HEART; IN VIVO STUDY; KIDNEY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; ORGAN; PANCREAS; POSITRON EMISSION TOMOGRAPHY; SPLEEN; ANIMAL; AUTORADIOGRAPHY; DOSE RESPONSE; ENZYMOLOGY; HEART MUSCLE; HUMAN; MALE; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; AUTORADIOGRAPHY; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIGENOMICS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; KIDNEY; MALE; MYOCARDIUM; PAPIO; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84907938314     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500872p     Document Type: Article

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