-
1
-
-
84863301039
-
Lipid digestion as a trigger for supersaturation: In vitro and in vivo evaluation of the utility of polymeric precipitation inhibitors in selfemulsifying drug delivery systems
-
M.U. Anby, H.D. Williams, M. McIntosh, H. Benameur, G.A. Edwards, C.W. Pouton, and C.J.H. Porter Lipid digestion as a trigger for supersaturation: in vitro and in vivo evaluation of the utility of polymeric precipitation inhibitors in selfemulsifying drug delivery systems Mol. Pharm. 9 2012 2063 2079
-
(2012)
Mol. Pharm.
, vol.9
, pp. 2063-2079
-
-
Anby, M.U.1
Williams, H.D.2
McIntosh, M.3
Benameur, H.4
Edwards, G.A.5
Pouton, C.W.6
Porter, C.J.H.7
-
2
-
-
80052265520
-
In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems
-
T.L. Anne, S. Philip, and M. Anette In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems Int. J. Pharm. 417 2011 245 255
-
(2011)
Int. J. Pharm.
, vol.417
, pp. 245-255
-
-
Anne, T.L.1
Philip, S.2
Anette, M.3
-
3
-
-
84055221829
-
Understanding lipid digestion in the GI tract for effective drug delivery
-
J.C. Bakala N'Goma, S. Amara, K. Dridi, V. Jannin, and F. Carriere Understanding lipid digestion in the GI tract for effective drug delivery Ther. Deliv. 3 2012 105 124
-
(2012)
Ther. Deliv.
, vol.3
, pp. 105-124
-
-
Bakala N'Goma, J.C.1
Amara, S.2
Dridi, K.3
Jannin, V.4
Carriere, F.5
-
4
-
-
84893047439
-
Fate of nanostructured lipid carriers (NLCs) following the oral route: Design, pharmacokinetics and biodistribution
-
A. Beloqui, M. Solinís Á, A. Delgado, C. Evora, A. Isla, and A. Rodríguez-Gascón Fate of nanostructured lipid carriers (NLCs) following the oral route: design, pharmacokinetics and biodistribution J. Microencaps. 31 2014 1 8
-
(2014)
J. Microencaps.
, vol.31
, pp. 1-8
-
-
Beloqui, A.1
Solinís Á., M.2
Delgado, A.3
Evora, C.4
Isla, A.5
Rodríguez-Gascón, A.6
-
5
-
-
33645459679
-
Evaluation of antioxidant activity and inhibitory effect on nitric oxide production of some common vegetables
-
J.Y. Bor, H.Y. Chen, and G.C. Yen Evaluation of antioxidant activity and inhibitory effect on nitric oxide production of some common vegetables J. Agric. Food Chem. 54 2006 1680 1686
-
(2006)
J. Agric. Food Chem.
, vol.54
, pp. 1680-1686
-
-
Bor, J.Y.1
Chen, H.Y.2
Yen, G.C.3
-
6
-
-
0034601204
-
Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs
-
T. Cershanik, and S. Benita Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs Eur. J. Pharm. Biopharm. 50 2000 179 188
-
(2000)
Eur. J. Pharm. Biopharm.
, vol.50
, pp. 179-188
-
-
Cershanik, T.1
Benita, S.2
-
7
-
-
56049116002
-
Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation
-
H.Q. Chen, Z.U. Jin, X.J. Wang, X.M. Xu, L. Deng, and J.W. Zhao Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation Neurosci. Lett. 448 2008 175 179
-
(2008)
Neurosci. Lett.
, vol.448
, pp. 175-179
-
-
Chen, H.Q.1
Jin, Z.U.2
Wang, X.J.3
Xu, X.M.4
Deng, L.5
Zhao, J.W.6
-
8
-
-
0029562489
-
Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects
-
P.P. Constantinides Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects Pharm. Res. 12 1995 1561 1572
-
(1995)
Pharm. Res.
, vol.12
, pp. 1561-1572
-
-
Constantinides, P.P.1
-
9
-
-
33750592309
-
Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: Correlation with in vivo data and the relationship to intra-enterocyte processes in rats
-
A. Dahan, and A. Hoffman Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: correlation with in vivo data and the relationship to intra-enterocyte processes in rats Pharm. Res. 23 2006 2165 2174
-
(2006)
Pharm. Res.
, vol.23
, pp. 2165-2174
-
-
Dahan, A.1
Hoffman, A.2
-
11
-
-
84879807012
-
In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine
-
R. Devraj, H.D. Williams, D.B. Warren, K. Mohsin, C.J.H. Porter, and C.W. Pouton In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine Eur. J. Pharm. Sci. 49 2013 748 760
-
(2013)
Eur. J. Pharm. Sci.
, vol.49
, pp. 748-760
-
-
Devraj, R.1
Williams, H.D.2
Warren, D.B.3
Mohsin, K.4
Porter, C.J.H.5
Pouton, C.W.6
-
12
-
-
70549111587
-
Formulating fluticasone propionate in novel PEG-containing nanostructured lipid carriers (PEG-NLC)
-
S. Doktorovová, J. Araújo, M.L. Garcia, E. Rakovský, and E.B. Souto Formulating fluticasone propionate in novel PEG-containing nanostructured lipid carriers (PEG-NLC) Colloids Surf. B Biointerfaces 75 2010 538 542
-
(2010)
Colloids Surf. B Biointerfaces
, vol.75
, pp. 538-542
-
-
Doktorovová, S.1
Araújo, J.2
Garcia, M.L.3
Rakovský, E.4
Souto, E.B.5
-
13
-
-
77955468413
-
Phospholipids and lipid-based formulations in oral drug delivery
-
G. Fricker, T. Kromp, A. Wendel, A. Blume, J. Zirkel, H. Rebmann, C. Setzer, R.O. Quinkert, C. Setzer, F. Martin, M.G. Christel, and C. Müller-Goymann Phospholipids and lipid-based formulations in oral drug delivery Pharm. Res. 27 2010 1469 1486
-
(2010)
Pharm. Res.
, vol.27
, pp. 1469-1486
-
-
Fricker, G.1
Kromp, T.2
Wendel, A.3
Blume, A.4
Zirkel, J.5
Rebmann, H.6
Setzer, C.7
Quinkert, R.O.8
Setzer, C.9
Martin, F.10
Christel, M.G.11
Müller-Goymann, C.12
-
14
-
-
57149103144
-
Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin
-
S. Günter, M. Irmgard, and M.S. Christoph Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin Planta Med. 74 2008 1667 1677
-
(2008)
Planta Med.
, vol.74
, pp. 1667-1677
-
-
Günter, S.1
Irmgard, M.2
Christoph, M.S.3
-
15
-
-
13844299448
-
Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages
-
S. Hougee, A. Sanders, J. Faber, Y.M. Graus, W.B. Van den Berg, J. Garssen, H.F. Smit, and M.A. Hoijer Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages Biochem. Pharmacol. 69 2005 241 248
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 241-248
-
-
Hougee, S.1
Sanders, A.2
Faber, J.3
Graus, Y.M.4
Van Den Berg, W.B.5
Garssen, J.6
Smit, H.F.7
Hoijer, M.A.8
-
16
-
-
0342617694
-
Lipid-based vehicles for the oral delivery of poorly water soluble drugs
-
A.J. Humberstone, and W.N. Charman Lipid-based vehicles for the oral delivery of poorly water soluble drugs Adv. Drug. Deliv. Rev 25 1997 103 128
-
(1997)
Adv. Drug. Deliv. Rev
, vol.25
, pp. 103-128
-
-
Humberstone, A.J.1
Charman, W.N.2
-
17
-
-
27144481028
-
Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy
-
K. Jores, A. Haberland, S. Wartewig, K. Mäder, and W. Mehnert Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy Pharm. Res. 22 2005 1887 1897
-
(2005)
Pharm. Res.
, vol.22
, pp. 1887-1897
-
-
Jores, K.1
Haberland, A.2
Wartewig, S.3
Mäder, K.4
Mehnert, W.5
-
18
-
-
0035201891
-
Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation
-
S. Kayoko, S. Noriko, N. Ryushi, S. Motoyoshi, A. Izumi, N. Tsutomu, and K. Naohide Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation Drug Metab. Dispos. 29 2001 1521 1524
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1521-1524
-
-
Kayoko, S.1
Noriko, S.2
Ryushi, N.3
Motoyoshi, S.4
Izumi, A.5
Tsutomu, N.6
Naohide, K.7
-
19
-
-
14044267753
-
Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity
-
B. Koen, V. Ruth, V. Guido, and V.S. Johannes Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity J. Biol. Chem. 280 2005 5636 5645
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 5636-5645
-
-
Koen, B.1
Ruth, V.2
Guido, V.3
Johannes, V.S.4
-
20
-
-
33644885997
-
Antioxidant enzymes activity involvement in luteolin-induced human lung squamous carcinoma CH27 cell apoptosis
-
H.W. Leunga, C.L. Kuob, W.H. Yangc, C.H. Lind, and H.Z. Lee Antioxidant enzymes activity involvement in luteolin-induced human lung squamous carcinoma CH27 cell apoptosis Eur. J. Pharmacol. 534 2006 12 18
-
(2006)
Eur. J. Pharmacol.
, vol.534
, pp. 12-18
-
-
Leunga, H.W.1
Kuob, C.L.2
Yangc, W.H.3
Lind, C.H.4
Lee, H.Z.5
-
21
-
-
80053565056
-
Bioadhesion and enhanced bioavailability by wheat germ agglutinin-grafted lipid nanoparticles for oral delivery of poorly water-soluble drug bufalin
-
Y. Liu, P.F. Wang, C. Sun, J.H. Zhao, Y. Du, F. Shi, and N.P. Feng Bioadhesion and enhanced bioavailability by wheat germ agglutinin-grafted lipid nanoparticles for oral delivery of poorly water-soluble drug bufalin Int. J. Pharm. 31 2011 260 265
-
(2011)
Int. J. Pharm.
, vol.31
, pp. 260-265
-
-
Liu, Y.1
Wang, P.F.2
Sun, C.3
Zhao, J.H.4
Du, Y.5
Shi, F.6
Feng, N.P.7
-
22
-
-
64149094878
-
Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery
-
Q.Z. Lu, A.H. Yu, and Y.W. Xi Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery Int. J. Pharm. 272 2009 191 198
-
(2009)
Int. J. Pharm.
, vol.272
, pp. 191-198
-
-
Lu, Q.Z.1
Yu, A.H.2
Xi, Y.W.3
-
23
-
-
84860625072
-
Absorption, distribution and pharmacokinetics of nanoemulsions
-
Y. Lu, J.P. Qi, and W. Wu Absorption, distribution and pharmacokinetics of nanoemulsions Cur. Drug Metab. 13 2012 396 417
-
(2012)
Cur. Drug Metab.
, vol.13
, pp. 396-417
-
-
Lu, Y.1
Qi, J.P.2
Wu, W.3
-
24
-
-
84877718885
-
Characterization and evaluation of an oral microemulsion containing the antitumor diterpenoid compound ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid
-
Y. Lu, K. Wu, L. Li, Y. He, L. Cui, N. Liang, and B. Mu Characterization and evaluation of an oral microemulsion containing the antitumor diterpenoid compound ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid Int. J. Nanomedicine 8 2013 1879 1886
-
(2013)
Int. J. Nanomedicine
, vol.8
, pp. 1879-1886
-
-
Lu, Y.1
Wu, K.2
Li, L.3
He, Y.4
Cui, L.5
Liang, N.6
Mu, B.7
-
25
-
-
60149091041
-
Synthesis and biological evaluation of novel luteolin derivatives as antibacterial agents
-
P.C. Lv, H.Q. Li, J.Y. Xue, L. Shi, and H.L. Zhu Synthesis and biological evaluation of novel luteolin derivatives as antibacterial agents Eur. J. Med. Chem. 44 2009 908 914
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 908-914
-
-
Lv, P.C.1
Li, H.Q.2
Xue, J.Y.3
Shi, L.4
Zhu, H.L.5
-
26
-
-
84862898541
-
Design of lipid-based formulations for oral administration of poorly water-soluble drug fenofibrate effects of digestion
-
H.L. Mu, H. Rene, and M. Anette Design of lipid-based formulations for oral administration of poorly water-soluble drug fenofibrate effects of digestion AAPS Pharm. Sci. Tech. 13 2013 637 646
-
(2013)
AAPS Pharm. Sci. Tech.
, vol.13
, pp. 637-646
-
-
Mu, H.L.1
Rene, H.2
Anette, M.3
-
27
-
-
0037151496
-
Nanostructured lipid matrices for improved microencapsulation of drugs
-
R.H. Muller, M. Radtke, and S.A. Wissing Nanostructured lipid matrices for improved microencapsulation of drugs Int. J. Pharm. 242 2002 121 128
-
(2002)
Int. J. Pharm.
, vol.242
, pp. 121-128
-
-
Muller, R.H.1
Radtke, M.2
Wissing, S.A.3
-
28
-
-
0037177514
-
Lipase degradation of Dynasan 114 and Dynasan 116 solid lipid nanoparticles (SLN) - Effect of surfactants storage time and crystallinity
-
C. Olbrich, O. Kayser, and R.H. Muller Lipase degradation of Dynasan 114 and Dynasan 116 solid lipid nanoparticles (SLN) - effect of surfactants storage time and crystallinity Int. J. Pharm. 237 2002 119 128
-
(2002)
Int. J. Pharm.
, vol.237
, pp. 119-128
-
-
Olbrich, C.1
Kayser, O.2
Muller, R.H.3
-
29
-
-
79960592269
-
Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs
-
L. Paula, K. Hanna, and L. Anni Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs Eur. J. Pharm. Biopharm. 78 2011 531 538
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.78
, pp. 531-538
-
-
Paula, L.1
Hanna, K.2
Anni, L.3
-
30
-
-
33847394968
-
Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs
-
C.J.H. Porter, N.L. Trevaskis, and W.N. Charman Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs Nat. Rev. Drug Discov. 6 2007 231 248
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 231-248
-
-
Porter, C.J.H.1
Trevaskis, N.L.2
Charman, W.N.3
-
31
-
-
0033805858
-
Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and self-microemulsifying drug delivery systems
-
C.W. Pouton Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and self-microemulsifying drug delivery systems Eur. J. Pharm. Sci. 11 2000 93 98
-
(2000)
Eur. J. Pharm. Sci.
, vol.11
, pp. 93-98
-
-
Pouton, C.W.1
-
32
-
-
84860640294
-
Absorption, distribution and pharmacokinetics of solid lipid nanoparticles
-
J.P. Qi, Y. Lu, and W. Wu Absorption, distribution and pharmacokinetics of solid lipid nanoparticles Cur. Drug Metab. 13 2012 418 428
-
(2012)
Cur. Drug Metab.
, vol.13
, pp. 418-428
-
-
Qi, J.P.1
Lu, Y.2
Wu, W.3
-
33
-
-
16344363233
-
Nanostructured lipid carriers: A novel generation of solid lipid drug carriers
-
M. Radtke, E.B. Souro, and R.H. Muller Nanostructured lipid carriers:a novel generation of solid lipid drug carriers Pharm. Technol. Eur. 17 2005 45 50
-
(2005)
Pharm. Technol. Eur.
, vol.17
, pp. 45-50
-
-
Radtke, M.1
Souro, E.B.2
Muller, R.H.3
-
34
-
-
84874669561
-
Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability
-
R. Sane, R.K. Mittapalli, and W.F. Elmquist Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability J. Pharm. Sci. 102 2013 1343 1354
-
(2013)
J. Pharm. Sci.
, vol.102
, pp. 1343-1354
-
-
Sane, R.1
Mittapalli, R.K.2
Elmquist, W.F.3
-
35
-
-
0035016152
-
Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products by HPTLC coupled with in situ densitometric analysis
-
L. Sek, C.J. Porter, and W.N. Charman Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products by HPTLC coupled with in situ densitometric analysis Biomed. Anal. 25 2001 651 661
-
(2001)
Biomed. Anal.
, vol.25
, pp. 651-661
-
-
Sek, L.1
Porter, C.J.2
Charman, W.N.3
-
36
-
-
84891590387
-
Binary lipids-based nanostructured lipid carriers for improved oral bioavailability of silymarin
-
M. Shangguan, Y. Lu, J. Qi, J. Han, Z. Tian, Y. Xie, F. Hu, H. Yuan, and W. Wu Binary lipids-based nanostructured lipid carriers for improved oral bioavailability of silymarin J. Biomater. Appl. 28 2014 887 896
-
(2014)
J. Biomater. Appl.
, vol.28
, pp. 887-896
-
-
Shangguan, M.1
Lu, Y.2
Qi, J.3
Han, J.4
Tian, Z.5
Xie, Y.6
Hu, F.7
Yuan, H.8
Wu, W.9
-
37
-
-
84861529172
-
In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
-
N. Thomas, R. Holm, A. Mullertz, and T. Rades In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) J. Control. Release 160 2012 25 32
-
(2012)
J. Control. Release
, vol.160
, pp. 25-32
-
-
Thomas, N.1
Holm, R.2
Mullertz, A.3
Rades, T.4
-
38
-
-
84881234825
-
Solidification of nanostructured lipid carrier (NLC) onto pellets by fluid-bed coating: Preparation, in vitro characterization and bioavailability in dogs
-
Z.Q. Tian, J.P. Qi, Y. i, J. Han, X. Yuan H. l. Zhang, Y.C. Xie, F.Q. Hu, Y. Lu, and W. Wu Solidification of nanostructured lipid carrier (NLC) onto pellets by fluid-bed coating: preparation, in vitro characterization and bioavailability in dogs Powder Technol. 247 2013 120 127
-
(2013)
Powder Technol.
, vol.247
, pp. 120-127
-
-
Tian, Z.Q.1
Qi, J.P.Y.I.2
Han, J.3
Yuan Zhang, L.H.X.4
Xie, Y.C.5
Hu, F.Q.6
Lu, Y.7
Wu, W.8
-
39
-
-
84890551417
-
Lipid-based formulations and drug supersaturation: Harnessing the unique benefits of the lipid digestion/absorption pathway
-
H.D. Williams, N.L. Trevaskis, Y.Y. Yeap, M.U. Anby, C.W. Pouton, and C.J. Porter Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway Pharm. Res. 30 2013 2976 2992
-
(2013)
Pharm. Res.
, vol.30
, pp. 2976-2992
-
-
Williams, H.D.1
Trevaskis, N.L.2
Yeap, Y.Y.3
Anby, M.U.4
Pouton, C.W.5
Porter, C.J.6
-
40
-
-
33646854907
-
Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system
-
W. Wu, Y. Wang, and L. Que Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system Eur. J. Pharm. Biopharm. 63 2006 288 294
-
(2006)
Eur. J. Pharm. Biopharm.
, vol.63
, pp. 288-294
-
-
Wu, W.1
Wang, Y.2
Que, L.3
|