메뉴 건너뛰기




Volumn 31, Issue 1, 2014, Pages 1-8

Fate of nanostructured lipid carriers (NLCs) following the oral route: Design, pharmacokinetics and biodistribution

Author keywords

Bioavailability; Biodistribution; Lipids; Nanoparticles; NLCs; Spironolactone

Indexed keywords

7ALPHA THIOMETHYLSPIRONOLACTONE; CANRENONE; LIPID; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; PANCREATIN; PEPSIN A; SPIRONOLACTONE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

EID: 84893047439     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2013.788090     Document Type: Article
Times cited : (41)

References (45)
  • 1
    • 34547800192 scopus 로고    scopus 로고
    • Freeze-drying of nanoparticles: Formulation, process and storage considerations
    • Abdelwahed W, Degobert G, Stainmesse S, Fessi H. Freeze-drying of nanoparticles: Formulation, process and storage considerations. Adv Drug Deliv Rev, 2006;58:1688-713
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1688-1713
    • Abdelwahed, W.1    Degobert, G.2    Stainmesse, S.3    Fessi, H.4
  • 2
    • 84055221829 scopus 로고    scopus 로고
    • Understanding lipid-digestion processes in the GI tract before designing lipid-based drug-delivery systems
    • Bakala N'Goma JC, Amara S, Dridi K, Jannin V, Carrière F. Understanding lipid-digestion processes in the GI tract before designing lipid-based drug-delivery systems. Ther Deliv, 2012;3:105-24
    • (2012) Ther Deliv , vol.3 , pp. 105-124
    • Bakala N'Goma, J.C.1    Amara, S.2    Dridi, K.3    Jannin, V.4    Carrière, F.5
  • 3
    • 68349160715 scopus 로고    scopus 로고
    • Lipid-An emerging platform for oral delivery of drugs with poor bioavailability
    • Chakraborty S, Shukla D, Mishra B, Singh S. Lipid-An emerging platform for oral delivery of drugs with poor bioavailability. Eur J Pharm Biopharm, 2009;73:1-15
    • (2009) Eur J Pharm Biopharm , vol.73 , pp. 1-15
    • Chakraborty, S.1    Shukla, D.2    Mishra, B.3    Singh, S.4
  • 5
    • 39149124830 scopus 로고    scopus 로고
    • Lipid excipients and delivery systems for pharmaceutical development: A regulatory perspective
    • Chen M. Lipid excipients and delivery systems for pharmaceutical development: A regulatory perspective. Adv Drug Deliv Rev, 2008; 60:768-77
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 768-777
    • Chen, M.1
  • 6
    • 77649184038 scopus 로고    scopus 로고
    • Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: Physicochemical characterization and pharmacokinetics
    • Chen CC, Tsai TH, Huang ZR, Fang JY. Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: Physicochemical characterization and pharmacokinetics. Eur J Pharm Biopharm, 2010;74:474-82
    • (2010) Eur J Pharm Biopharm , vol.74 , pp. 474-482
    • Chen, C.C.1    Tsai, T.H.2    Huang, Z.R.3    Fang, J.Y.4
  • 7
    • 34250867442 scopus 로고    scopus 로고
    • The effect of different lipid based formulations on the oral absorption of lipophilic drugs: The ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats
    • Dahan A, Hoffman A. The effect of different lipid based formulations on the oral absorption of lipophilic drugs: The ability of in vitro lipolysis and consecutive ex vivo intestinal permeability data to predict in vivo bioavailability in rats. Eur J Pharm Biopharm, 2007;67:96-105
    • (2007) Eur J Pharm Biopharm , vol.67 , pp. 96-105
    • Dahan, A.1    Hoffman, A.2
  • 8
    • 44649133855 scopus 로고    scopus 로고
    • Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs
    • Dahan A, Hoffman A. Rationalizing the selection of oral lipid based drug delivery systems by an in vitro dynamic lipolysis model for improved oral bioavailability of poorly water soluble drugs. J Control Release, 2008;129:1-10
    • (2008) J Control Release , vol.129 , pp. 1-10
    • Dahan, A.1    Hoffman, A.2
  • 9
    • 79954417472 scopus 로고    scopus 로고
    • Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery
    • Das S, Chaudhury A. Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery. AAPS PharmSciTech, 2011; 12:62-76
    • (2011) AAPS PharmSciTech , vol.12 , pp. 62-76
    • Das, S.1    Chaudhury, A.2
  • 10
  • 12
    • 21744458087 scopus 로고    scopus 로고
    • Nanoparticle uptake by the oral route: Fulfilling its potential?
    • Florence AT. Nanoparticle uptake by the oral route: Fulfilling its potential? Drug Discov Today: Technol, 2005;2:75-81
    • (2005) Drug Discov Today: Technol , vol.2 , pp. 75-81
    • Florence, A.T.1
  • 13
    • 0035478442 scopus 로고    scopus 로고
    • Transcytosis of nanoparticle and dendrimer delivery systems: Evolving vistas
    • Florence AT, Hussain N. Transcytosis of nanoparticle and dendrimer delivery systems: Evolving vistas. Adv Drug Deliv Rev, 2001;50: S69-89
    • (2001) Adv Drug Deliv Rev , vol.50
    • Florence, A.T.1    Hussain, N.2
  • 15
    • 34548049221 scopus 로고    scopus 로고
    • Oral lipid-based formulations
    • Hauss DJ. Oral lipid-based formulations. Adv Drug Deliv Rev, 2007;59: 667-76
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 667-676
    • Hauss, D.J.1
  • 16
    • 38949117575 scopus 로고    scopus 로고
    • Approaches for the development of solid and semi-solid lipid-based formulations
    • Jannin V, Musakhanian J, Marchaud D. Approaches for the development of solid and semi-solid lipid-based formulations. Adv Drug Deliv Rev, 2008;60:734-46
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 734-746
    • Jannin, V.1    Musakhanian, J.2    Marchaud, D.3
  • 17
    • 34548049483 scopus 로고    scopus 로고
    • Nanosizing-Oral formulation development and biopharmaceutical evaluation
    • Kesisoglou F, Panmai S, Wu Y. Nanosizing-Oral formulation development and biopharmaceutical evaluation. Adv Drug Deliv Rev, 2007;59:631-44
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 631-644
    • Kesisoglou, F.1    Panmai, S.2    Wu, Y.3
  • 18
    • 0037148679 scopus 로고    scopus 로고
    • Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles
    • Konan YN, Gurny R, Allémann E. Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles. Int J Pharm, 2002; 233:239-52
    • (2002) Int J Pharm , vol.233 , pp. 239-252
    • Konan, Y.N.1    Gurny, R.2    Allémann, E.3
  • 19
    • 79957789430 scopus 로고    scopus 로고
    • Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs
    • Krishnaiah YSR. Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs. J Bioequiv Availab, 2010;2:28-36
    • (2010) J Bioequiv Availab , vol.2 , pp. 28-36
    • Krishnaiah, Y.S.R.1
  • 21
    • 33750269368 scopus 로고    scopus 로고
    • Preparation and characterization of spironolactone-loaded nanocapsules for paediatric use
    • Limayem Blouza I, Charcosset C, Sfar S, Fessi H. Preparation and characterization of spironolactone-loaded nanocapsules for paediatric use. Int J Pharm, 2006;325:124-31
    • (2006) Int J Pharm , vol.325 , pp. 124-131
    • Limayem Blouza, I.1    Charcosset, C.2    Sfar, S.3    Fessi, H.4
  • 22
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • Mehnert W, Mäder K. Solid lipid nanoparticles: Production, characterization and applications. Adv Drug Deliv Rev, 2001;47:165-96
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 165-196
    • Mehnert, W.1    Mäder, K.2
  • 23
    • 41949100244 scopus 로고    scopus 로고
    • Drug nanoparticles: Formulating poorly water-soluble compounds
    • Merisko-Liversidge E, Liversidge G. Drug nanoparticles: Formulating poorly water-soluble compounds. Toxicol Pathol, 2008;36:43-8
    • (2008) Toxicol Pathol , vol.36 , pp. 43-48
    • Merisko-Liversidge, E.1    Liversidge, G.2
  • 24
    • 79957861493 scopus 로고    scopus 로고
    • Nanosizing for oral and parenteral drug delivery: A perspective on formulating poorly-water soluble compounds using wet media milling technology
    • Merisko-Liversidge E, Liversidge GG. Nanosizing for oral and parenteral drug delivery: A perspective on formulating poorly-water soluble compounds using wet media milling technology. Adv Drug Deliv Rev, 2011;63:427-40
    • (2011) Adv Drug Deliv Rev , vol.63 , pp. 427-440
    • Merisko-Liversidge, E.1    Liversidge, G.G.2
  • 25
    • 0037312695 scopus 로고    scopus 로고
    • Nanosizing: A formulation approach for poorly-water-soluble compounds
    • Merisko-Liversidge E, Liversidge GG, Cooper ER. Nanosizing: A formulation approach for poorly-water-soluble compounds. Eur J Pharm Sci, 2003;18:113-20
    • (2003) Eur J Pharm Sci , vol.18 , pp. 113-120
    • Merisko-Liversidge, E.1    Liversidge, G.G.2    Cooper, E.R.3
  • 26
    • 57349171371 scopus 로고    scopus 로고
    • Lipid nanoparticles with a solid matrix (SLN, NLC, LDC) for oral drug delivery
    • Muchow M, Maincent P, Müller R. Lipid nanoparticles with a solid matrix (SLN, NLC, LDC) for oral drug delivery. Drug Dev Ind Pharm, 2008;34:1394-405
    • (2008) Drug Dev Ind Pharm , vol.34 , pp. 1394-1405
    • Muchow, M.1    Maincent, P.2    Müller, R.3
  • 27
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery-A review of the state of the art
    • Müller R, Mäder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery-A review of the state of the art. Eur J Pharm Biopharm, 2000;50:161-77
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 161-177
    • Müller, R.1    Mäder, K.2    Gohla, S.3
  • 28
    • 0037151496 scopus 로고    scopus 로고
    • Nanostructured lipid matrices for improved microencapsulation of drugs
    • Müller RH, Radtke M, Wissing SA. Nanostructured lipid matrices for improved microencapsulation of drugs. Int J Pharm, 2002;242:121-8
    • (2002) Int J Pharm , vol.242 , pp. 121-128
    • Müller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 29
    • 33744973517 scopus 로고    scopus 로고
    • Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN-) versus drug nanocrystals
    • Müller RH, Runge S, Ravelli V, Mehnert W, Thünemann AF, Souto EB. Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN-) versus drug nanocrystals. Int J Pharm, 2006;317:82-89
    • (2006) Int J Pharm , vol.317 , pp. 82-89
    • Müller, R.H.1    Runge, S.2    Ravelli, V.3    Mehnert, W.4    Thünemann, A.F.5    Souto, E.B.6
  • 30
    • 78049499869 scopus 로고    scopus 로고
    • New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
    • Müllertz A, Ogbonna A, Ren S, Rades T. New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs. J Pharm Pharmacol, 2010;62:1622-36
    • (2010) J Pharm Pharmacol , vol.62 , pp. 1622-1636
    • Müllertz, A.1    Ogbonna, A.2    Ren, S.3    Rades, T.4
  • 31
    • 39149126301 scopus 로고    scopus 로고
    • Biopharmaceutical challenges associated with drugs with low aqueous solubility-The potential impact of lipidbased formulations
    • O'Driscoll CM, Griffin BT. Biopharmaceutical challenges associated with drugs with low aqueous solubility-The potential impact of lipidbased formulations. Adv Drug Deliv Rev, 2008;60:617-24
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 617-624
    • O'Driscoll, C.M.1    Griffin, B.T.2
  • 32
    • 0023512031 scopus 로고
    • The metabolism and biopharmaceutics of spironolactone in man
    • Overdiek HW, Merkus FW. The metabolism and biopharmaceutics of spironolactone in man. RevDrug Metab Drug Interact, 1987;5:273-302
    • (1987) RevDrug Metab Drug Interact , vol.5 , pp. 273-302
    • Overdiek, H.W.1    Merkus, F.W.2
  • 33
    • 33847394968 scopus 로고    scopus 로고
    • Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs
    • Porter C, Trevaskis N, Charman W. Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov, 2007;6:231-48
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 231-248
    • Porter, C.1    Trevaskis, N.2    Charman, W.3
  • 34
    • 39149092022 scopus 로고    scopus 로고
    • Enhancing intestinal drug solubilisation using lipid-based delivery systems
    • Porter CJH, Pouton CW, Cuine JF, Charman WN. Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv Drug Deliv Rev, 2008;60:673-91
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 673-691
    • Porter, C.J.H.1    Pouton, C.W.2    Cuine, J.F.3    Charman, W.N.4
  • 35
    • 33751014029 scopus 로고    scopus 로고
    • Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system
    • Pouton CW. Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system. Eur J Pharm Sci, 2006;29:278-87
    • (2006) Eur J Pharm Sci , vol.29 , pp. 278-287
    • Pouton, C.W.1
  • 36
    • 39149113817 scopus 로고    scopus 로고
    • Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies
    • Pouton CW, Porter CJH. Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies. Adv Drug Deliv Rev, 2008;60:625-37
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 625-637
    • Pouton, C.W.1    Porter, C.J.H.2
  • 38
    • 0016164945 scopus 로고
    • Intestinal absorption of pertechnetate: Calculation by the oral-intravenous plasma activity quotients and inverse convolution method
    • Szymendera J, Radwan M. Intestinal absorption of pertechnetate: Calculation by the oral-intravenous plasma activity quotients and inverse convolution method. J Nucl Med, 1974;15:314-16
    • (1974) J Nucl Med , vol.15 , pp. 314-316
    • Szymendera, J.1    Radwan, M.2
  • 39
    • 0024565173 scopus 로고
    • Enhanced intestinal absorption of cyclosporine in rats through the reduction of emulsion droplet size
    • Tarr BD, Yalkowsky SH. Enhanced intestinal absorption of cyclosporine in rats through the reduction of emulsion droplet size. Pharm Res, 1989;6:40-3
    • (1989) Pharm Res , vol.6 , pp. 40-43
    • Tarr, B.D.1    Yalkowsky, S.H.2
  • 40
    • 34447305482 scopus 로고    scopus 로고
    • Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)-Effects of formulation parameters on physicochemical stability
    • Teeranachaideekul V, Mü ller RH, Junyaprasert VB. Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC)-Effects of formulation parameters on physicochemical stability. Int J Pharm, 2007;340:198-206
    • (2007) Int J Pharm , vol.340 , pp. 198-206
    • Teeranachaideekul, V.1    Müller, R.H.2    Junyaprasert, V.B.3
  • 41
    • 39149108776 scopus 로고    scopus 로고
    • Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update
    • Trevaskis NL, Charman WN, Porter CJH. Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update. Adv Drug Deliv Rev, 2008;60:702-16
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 702-716
    • Trevaskis, N.L.1    Charman, W.N.2    Porter, C.J.H.3
  • 42
    • 0003484310 scopus 로고    scopus 로고
    • US Food And Drug Administration. Rockville: Centre for Drug Evaluation and Research (CDER
    • US Food and Drug Administration. Guidance for Industry, Bioanalytical Method Validation. 2001. Rockville: Centre for Drug Evaluation and Research (CDER
    • (2001) Guidance For Industry Bioanalytical Method Validation
  • 43
    • 84860570421 scopus 로고    scopus 로고
    • Design and evaluation of polymer coated carvedilol loaded solid lipid nanoparticles to improve the oral bioavailability: A novel strategy to avoid intraduodenal administration
    • Venishetty VK, Chede R, Komuravelli R, Adepu L, Sistla R, Diwan PV. Design and evaluation of polymer coated carvedilol loaded solid lipid nanoparticles to improve the oral bioavailability: A novel strategy to avoid intraduodenal administration. Colloids Surf B Biointerfaces, 2012;95:1-9
    • (2012) Colloids Surf B Biointerfaces , vol.95 , pp. 1-9
    • Venishetty, V.K.1    Chede, R.2    Komuravelli, R.3    Adepu, L.4    Sistla, R.5    Diwan, P.V.6
  • 44
    • 84864051006 scopus 로고    scopus 로고
    • Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterisation and comparison of in vitro digestion profiles across a range of representative formulations
    • Williams H, Sassene P, Kleberg K, Bakala N, Goma JC, Calderone M, Jannin V, Igonin A, Partheli A, Marchaud D, Vertommen J, et al. Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterisation and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci, 2012;101:3360-80
    • (2012) J Pharm Sci , vol.101 , pp. 3360-3380
    • Williams, H.1    Sassene, P.2    Kleberg, K.3    Bakala, N.4    Goma, J.C.5    Calderone, M.6    Jannin, V.7    Igonin, A.8    Partheli, A.9    Marchaud, D.10    Vertommen, J.11
  • 45
    • 77955928055 scopus 로고    scopus 로고
    • Biodistribution and toxicity of nanodiamonds in mice after intratracheal instillation
    • Zhang X, Yin J, Kang C, Li J, Zhu Y, Li W, Huang Q, Zhu Z. Biodistribution and toxicity of nanodiamonds in mice after intratracheal instillation. Toxicol Lett, 2010;198:237-43
    • (2010) Toxicol Lett , vol.198 , pp. 237-243
    • Zhang, X.1    Yin, J.2    Kang, C.3    Li, J.4    Zhu, Y.5    Li, W.6    Huang, Q.7    Zhu, Z.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.