In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine

European Journal of Pharmaceutical Sciences

Volumn 49, Issue 4, 2013, Pages 748-760

  Devraj, Ravi ^a   Williams, Hywel D ^a,b   Warren, Dallas B ^a   Mohsin, Kazi ^a,c   Porter, Christopher J H ^a   Pouton, Colin W ^a  

^a MONASH UNIVERSITY   (Australia)

^b CAPSUGEL   (France)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Digestion; LFCS; Lipid based drug delivery systems; Poorly water soluble drugs; Precipitation; Supersaturation

Indexed keywords

FENOFIBRATE; LIPID; POLYSORBATE 80; POLYSORBATE 85; SOLVENT; UNCLASSIFIED DRUG; WATER;

ARTICLE; DIGESTION; DISPERSION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG SOLUBILITY; IN VITRO STUDY; LIPID BASED FORMULATION; LIPID COMPOSITION; PRECIPITATION; PRIORITY JOURNAL; SOLUBILIZATION;

EID: 84879807012     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.04.036     Document Type: Article

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