Mechanically-compliant intracortical implants reduce the neuroinflammatory response

Journal of Neural Engineering

Volumn 11, Issue 5, 2014, Pages

  Nguyen, Jessica K ^a,b   Park, Daniel J ^a   Skousen, John L ^b   Hess Dunning, Allison E ^b   Tyler, Dustin J ^a,b   Rowan, Stuart J ^a,c   Weder, Christoph ^c,d   Capadona, Jeffrey R ^a,b  

^a Case Western Reserve University   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c Case Western Reserve University   (United States)

^d UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

biomimetic material; foreign body response; intracortical microelectrode; mechanical properties; nanocomposite

Indexed keywords

BIOMIMETIC MATERIALS; BIOMIMETICS; ELECTRODES; MECHANICAL PROPERTIES; MICROELECTRODES; NANOCOMPOSITES; NEURODEGENERATIVE DISEASES; TISSUE;

BLOOD-BRAIN BARRIER; COMPLIANT MATERIALS; FOREIGN BODY RESPONSE; IMPLANT MATERIALS; MECHANICALLY ADAPTIVE; NEURODEGENERATIVE; POST-IMPLANTATION; REFERENCE MATERIAL;

BIOMECHANICS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; HEALING; INTRACORTICAL IMPLANT; MALE; MICROELECTRODE; NERVOUS SYSTEM INFLAMMATION; NEUROLOGICAL IMPLANT; NONHUMAN; RAT; RIGIDITY; TISSUE REACTION; ADVERSE EFFECTS; ANIMAL; COMPUTER AIDED DESIGN; DEVICE FAILURE ANALYSIS; ELASTICITY; ELECTRODE IMPLANT; ENCEPHALITIS; MATERIALS TESTING; PATHOLOGY; PROSTHESIS; SPRAGUE DAWLEY RAT;

BIOMATERIAL;

ANIMALS; COATED MATERIALS, BIOCOMPATIBLE; COMPUTER-AIDED DESIGN; ELASTICITY; ELECTRODES, IMPLANTED; ENCEPHALITIS; EQUIPMENT FAILURE ANALYSIS; MALE; MATERIALS TESTING; MICROELECTRODES; PROSTHESIS DESIGN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84907909025     PISSN: 17412560     EISSN: 17412552     Source Type: Journal    
DOI: 10.1088/1741-2560/11/5/056014     Document Type: Article

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