메뉴 건너뛰기




Volumn 88, Issue 20, 2014, Pages 11648-11657

Effect of vaginal immunization with HIVgp140 and HSP70 on HIV-1 replication and innate and T cell adaptive immunity in women

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CN54GP140 GLYCOPROTEIN HSP70 CONJUGATE VACCINE; GAMMA INTERFERON; GLYCOPROTEIN GP 140; HEAT SHOCK PROTEIN 70; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 12; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PLACEBO; RANTES; UNCLASSIFIED DRUG; GLYCOPROTEIN GP 41; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

EID: 84907907838     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01621-14     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 84894611393 scopus 로고    scopus 로고
    • Another HIV vaccine failure: where to next?
    • McMichael A, Picker LJ, Moore JP, Burton DR. 2013. Another HIV vaccine failure: where to next? Nat. Med. 19:1576-1577. http://dx.doi.org /10.1038/nm.3413.
    • (2013) Nat Med. , vol.19 , pp. 1576-1577
    • McMichael, A.1    Picker, L.J.2    Moore, J.P.3    Burton, D.R.4
  • 2
    • 77955513770 scopus 로고    scopus 로고
    • Overview of STEP and Phambili trial results:twophase IIb test-of-concept studies investigating the efficacy ofMRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine
    • Gray G, Buchbinder S, Duerr A. 2010. Overview of STEP and Phambili trial results:twophase IIb test-of-concept studies investigating the efficacy ofMRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine. Curr. Opin. HIV AIDS 5:357-361. http://dx.doi.org/10.1097/COH.0b013e32833d2d2b.
    • (2010) Curr. Opin. HIV AIDS , vol.5 , pp. 357-361
    • Gray, G.1    Buchbinder, S.2    Duerr, A.3
  • 3
    • 84880329495 scopus 로고    scopus 로고
    • Progress in HIV-1 vaccine development
    • Haynes BF, McElrath MJ. 2013. Progress in HIV-1 vaccine development. Curr. Opin. HIV AIDS 8:326-332. http://dx.doi.org/10.1097/COH.0b013e328361d178.
    • (2013) Curr. Opin. HIV AIDS , vol.8 , pp. 326-332
    • Haynes, B.F.1    McElrath, M.J.2
  • 6
    • 0037043699 scopus 로고    scopus 로고
    • Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
    • Sheehy AM, Gaddis NC, Choi JD, Malim MH. 2002. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418:646-650. http://dx.doi.org/10.1038/nature00939.
    • (2002) Nature , vol.418 , pp. 646-650
    • Sheehy, A.M.1    Gaddis, N.C.2    Choi, J.D.3    Malim, M.H.4
  • 7
    • 33846514832 scopus 로고    scopus 로고
    • Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells
    • Pido-Lopez J, Whittall T, Wang Y, Bergmeier LA, Babaahmady K, Singh M, Lehner T. 2007. Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells. J. Immunol. 178:1671-1679. http://dx.doi.org/10.4049/jimmunol.178.3.1671.
    • (2007) J. Immunol. , vol.178 , pp. 1671-1679
    • Pido-Lopez, J.1    Whittall, T.2    Wang, Y.3    Bergmeier, L.A.4    Babaahmady, K.5    Singh, M.6    Lehner, T.7
  • 8
    • 58249095268 scopus 로고    scopus 로고
    • Mucosal immunization in macaques upregulates the innate APOBEC 3G anti-viral factor in CD4(+) memory T cells
    • Wang Y, Bergmeier LA, Stebbings R, Seidl T, Whittall T, Singh M, Berry N, Almond N, Lehner T. 2009. Mucosal immunization in macaques upregulates the innate APOBEC 3G anti-viral factor in CD4(+) memory T cells. Vaccine 27:870-881. http://dx.doi.org/10.1016/j.vaccine.2008.11.084.
    • (2009) Vaccine , vol.27 , pp. 870-881
    • Wang, Y.1    Bergmeier, L.A.2    Stebbings, R.3    Seidl, T.4    Whittall, T.5    Singh, M.6    Berry, N.7    Almond, N.8    Lehner, T.9
  • 9
    • 79953204695 scopus 로고    scopus 로고
    • Heat shock protein 70 inhibits HIV-1 Vifmediated ubiquitination and degradation of APOBEC3G
    • Sugiyama R, Nishitsuji H, Furukawa A, Katahira M, Habu Y, Takeuchi H, Ryo A, Takaku H. 2011. Heat shock protein 70 inhibits HIV-1 Vifmediated ubiquitination and degradation of APOBEC3G. J. Biol. Chem. 286:10051-10057. http://dx.doi.org/10.1074/jbc.M110.166108.
    • (2011) J. Biol. Chem. , vol.286 , pp. 10051-10057
    • Sugiyama, R.1    Nishitsuji, H.2    Furukawa, A.3    Katahira, M.4    Habu, Y.5    Takeuchi, H.6    Ryo, A.7    Takaku, H.8
  • 10
    • 0034469646 scopus 로고    scopus 로고
    • Characterization of a virtually full-length human immunodeficiency virus type 1 genome of a prevalent intersubtype (C/B') recombinant strain in China
    • Su L, Graf M, Zhang Y, von Briesen H, Xing H, Kostler J, Melzl H, Wolf H, Shao Y, Wagner R. 2000. Characterization of a virtually full-length human immunodeficiency virus type 1 genome of a prevalent intersubtype (C/B') recombinant strain in China. J. Virol. 74:11367-11376. http: //dx.doi.org/10.1128/JVI.74.23.11367-11376.2000.
    • (2000) J. Virol. , vol.74 , pp. 11367-11376
    • Su, L.1    Graf, M.2    Zhang, Y.3    von Briesen, H.4    Xing, H.5    Kostler, J.6    Melzl, H.7    Wolf, H.8    Shao, Y.9    Wagner, R.10
  • 11
    • 0036512171 scopus 로고    scopus 로고
    • Roles of heat-shock proteins in innate and adaptive immunity
    • Srivastava P. 2002. Roles of heat-shock proteins in innate and adaptive immunity. Nat. Rev. Immunol. 2:185-194. http://dx.doi.org/10.1038 /nri749.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 185-194
    • Srivastava, P.1
  • 12
    • 0033566936 scopus 로고    scopus 로고
    • The HSC73 molecular chaperone: involvement in MHC class II antigen presentation
    • Panjwani N, Akbari O, Garcia S, Brazil M, Stockinger B. 1999. The HSC73 molecular chaperone: involvement in MHC class II antigen presentation. J. Immunol. 163:1936-1942.
    • (1999) J. Immunol. , vol.163 , pp. 1936-1942
    • Panjwani, N.1    Akbari, O.2    Garcia, S.3    Brazil, M.4    Stockinger, B.5
  • 13
    • 0034608370 scopus 로고    scopus 로고
    • Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
    • Castellino F, Boucher PE, Eichelberg K, Mayhew M, Rothman JE, Houghton AN, Germain RN. 2000. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways. J. Exp. Med. 191:1957-1964. http://dx.doi.org/10.1084/jem.191.11.1957.
    • (2000) J. Exp. Med. , vol.191 , pp. 1957-1964
    • Castellino, F.1    Boucher, P.E.2    Eichelberg, K.3    Mayhew, M.4    Rothman, J.E.5    Houghton, A.N.6    Germain, R.N.7
  • 15
    • 0036721692 scopus 로고    scopus 로고
    • Stimulation of Th1-polarizing cytokines, C-C chemokines, maturation of dendritic cells, and adjuvant function by the peptide binding fragment of heat shock protein 70
    • Wang Y, Kelly CG, Singh M, McGowan EG, Carrara AS, Bergmeier LA, Lehner T. 2002. Stimulation of Th1-polarizing cytokines, C-C chemokines, maturation of dendritic cells, and adjuvant function by the peptide binding fragment of heat shock protein 70. J. Immunol. 169:2422-2429. http://dx.doi.org/10.4049/jimmunol.169.5.2422.
    • (2002) J. Immunol. , vol.169 , pp. 2422-2429
    • Wang, Y.1    Kelly, C.G.2    Singh, M.3    McGowan, E.G.4    Carrara, A.S.5    Bergmeier, L.A.6    Lehner, T.7
  • 16
    • 69249150892 scopus 로고    scopus 로고
    • The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity
    • Pido-Lopez J, Wang Y, Seidl T, Babaahmady K, Vaughan R, Lehner T. 2009. The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity. Eur. J. Immunol. 39:1956-1965. http://dx.doi.org/10.1002/eji.200939228.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1956-1965
    • Pido-Lopez, J.1    Wang, Y.2    Seidl, T.3    Babaahmady, K.4    Vaughan, R.5    Lehner, T.6
  • 17
    • 0037144808 scopus 로고    scopus 로고
    • CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes
    • Becker T, Hartl FU, Wieland F. 2002. CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. J. Cell Biol. 158:1277-1285. http://dx.doi.org/10.1083/jcb.200208083.
    • (2002) J. Cell Biol. , vol.158 , pp. 1277-1285
    • Becker, T.1    Hartl, F.U.2    Wieland, F.3
  • 20
    • 33947360705 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 infection of human CD4+ T cells by microbial HSP70 and the peptide epitope 407-426
    • Babaahmady K, Oehlmann W, Singh M, Lehner T. 2007. Inhibition of human immunodeficiency virus type 1 infection of human CD4+ T cells by microbial HSP70 and the peptide epitope 407-426. J. Virol. 81:3354-3360. http://dx.doi.org/10.1128/JVI.02320-06.
    • (2007) J. Virol. , vol.81 , pp. 3354-3360
    • Babaahmady, K.1    Oehlmann, W.2    Singh, M.3    Lehner, T.4
  • 22
    • 0028143093 scopus 로고
    • Heat shock proteins as carrier molecules: in vivo helper effect mediated by Escherichia coli GroEL and DnaK proteins requires cross-linking with antigen
    • Barrios C, Georgopoulos C, Lambert PH, Del Giudice G. 1994. Heat shock proteins as carrier molecules: in vivo helper effect mediated by Escherichia coli GroEL and DnaK proteins requires cross-linking with antigen. Clin. Exp. Immunol. 98:229-233.
    • (1994) Clin. Exp. Immunol. , vol.98 , pp. 229-233
    • Barrios, C.1    Georgopoulos, C.2    Lambert, P.H.3    Del Giudice, G.4
  • 23
    • 70350572286 scopus 로고    scopus 로고
    • Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune re-sponses
    • Curran RM, Donnelly L, Morrow RJ, Fraser C, Andrews G, Cranage M, Malcolm RK, Shattock RJ, Woolfson AD. 2009. Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune re-sponses. Vaccine 27:6791-6798. http://dx.doi.org/10.1016/j.vaccine.2009.08.088.
    • (2009) Vaccine , vol.27 , pp. 6791-6798
    • Curran, R.M.1    Donnelly, L.2    Morrow, R.J.3    Fraser, C.4    Andrews, G.5    Cranage, M.6    Malcolm, R.K.7    Shattock, R.J.8    Woolfson, A.D.9
  • 25
    • 71049188827 scopus 로고    scopus 로고
    • Heterosexual and homosexual partners practising unprotected sex may develop allogeneic immunity and to a lesser extent tolerance
    • Kingsley C, Peters B, Babaahmady K, Pomeroy L, Rahman D, Vaughan R, Lehner T. 2009. Heterosexual and homosexual partners practising unprotected sex may develop allogeneic immunity and to a lesser extent tolerance. PLoS One 4:e7938. http://dx.doi.org/10.1371/journal.pone.0007938.
    • (2009) PLoS One , vol.4 , pp. e7938
    • Kingsley, C.1    Peters, B.2    Babaahmady, K.3    Pomeroy, L.4    Rahman, D.5    Vaughan, R.6    Lehner, T.7
  • 26
    • 5444234216 scopus 로고    scopus 로고
    • The interface between innate and adaptive immunity
    • Hoebe K, Janssen E, Beutler B. 2004. The interface between innate and adaptive immunity. Nat. Immunol. 5:971-974. http://dx.doi.org/10.1038 /ni1004-971.
    • (2004) Nat. Immunol. , vol.5 , pp. 971-974
    • Hoebe, K.1    Janssen, E.2    Beutler, B.3
  • 28
    • 0030587188 scopus 로고    scopus 로고
    • Mucosal or targeted lymph node immunization of macaques with a particulate SIVp27 protein elicits virusspecific CTL in the genito-rectal mucosa and draining lymph nodes
    • Klavinskis LS, Bergmeier LA, Gao L, Mitchell E, Ward RG, Layton G, Brookes R, Meyers NJ, Lehner T. 1996. Mucosal or targeted lymph node immunization of macaques with a particulate SIVp27 protein elicits virusspecific CTL in the genito-rectal mucosa and draining lymph nodes. J. Immunol. 157:2521-2527.
    • (1996) J. Immunol. , vol.157 , pp. 2521-2527
    • Klavinskis, L.S.1    Bergmeier, L.A.2    Gao, L.3    Mitchell, E.4    Ward, R.G.5    Layton, G.6    Brookes, R.7    Meyers, N.J.8    Lehner, T.9
  • 29
    • 27644446403 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques
    • Wang Y, Abel K, Lantz K, Krieg AM, McChesney MB, Miller CJ. 2005. The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques. J. Virol. 79:14355-14370. http: //dx.doi.org/10.1128/JVI.79.22.14355-14370.2005.
    • (2005) J. Virol. , vol.79 , pp. 14355-14370
    • Wang, Y.1    Abel, K.2    Lantz, K.3    Krieg, A.M.4    McChesney, M.B.5    Miller, C.J.6
  • 30
    • 0036644724 scopus 로고    scopus 로고
    • Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle
    • Kozlowski PA, Williams SB, Lynch RM, Flanigan TP, Patterson RR, Cu-Uvin S, Neutra MR. 2002. Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle. J. Immunol. 169:566-574. http://dx.doi.org/10.4049/jimmunol.169.1.566.
    • (2002) J. Immunol. , vol.169 , pp. 566-574
    • Kozlowski, P.A.1    Williams, S.B.2    Lynch, R.M.3    Flanigan, T.P.4    Patterson, R.R.5    Cu-Uvin, S.6    Neutra, M.R.7
  • 31
    • 84866182030 scopus 로고    scopus 로고
    • Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys
    • Stephenson KE, Li H, Walker BD, Michael NL, Barouch DH. 2012. Gag-specific cellular immunity determines in vitro viral inhibition and in vivo virologic control following simian immunodeficiency virus challenges of vaccinated rhesus monkeys. J. Virol. 86:9583-9589. http://dx.doi.org/10.1128/JVI.00996-12.
    • (2012) J. Virol. , vol.86 , pp. 9583-9589
    • Stephenson, K.E.1    Li, H.2    Walker, B.D.3    Michael, N.L.4    Barouch, D.H.5
  • 32
    • 0030018156 scopus 로고    scopus 로고
    • CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
    • Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA. 1996. CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958. http://dx.doi.org/10.1126/science.272.5270.1955.
    • (1996) Science , vol.272 , pp. 1955-1958
    • Alkhatib, G.1    Combadiere, C.2    Broder, C.C.3    Feng, Y.4    Kennedy, P.E.5    Murphy, P.M.6    Berger, E.A.7
  • 35
    • 0029417004 scopus 로고
    • Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
    • Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. 1995. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 270: 1811-1815. http://dx.doi.org/10.1126/science.270.5243.1811.
    • (1995) Science , vol.270 , pp. 1811-1815
    • Cocchi, F.1    DeVico, A.L.2    Garzino-Demo, A.3    Arya, S.K.4    Gallo, R.C.5    Lusso, P.6
  • 36
    • 0032847128 scopus 로고    scopus 로고
    • Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and resistance to HIV infection in women
    • Wang Y, Tao L, Mitchell E, Bravery C, Berlingieri P, Armstrong P, Vaughan R, Underwood J, Lehner T. 1999. Allo-immunization elicits CD8+ T cell-derived chemokines, HIV suppressor factors and resistance to HIV infection in women. Nat. Med. 5:1004-1009. http://dx.doi.org/10.1038/12440.
    • (1999) Nat. Med. , vol.5 , pp. 1004-1009
    • Wang, Y.1    Tao, L.2    Mitchell, E.3    Bravery, C.4    Berlingieri, P.5    Armstrong, P.6    Vaughan, R.7    Underwood, J.8    Lehner, T.9
  • 38
    • 0033976502 scopus 로고    scopus 로고
    • Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity
    • Lehner T, Bergmeier LA, Wang Y, Tao L, Sing M, Spallek R, van der Zee R. 2000. Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity. Eur. J. Immunol. 30:594-603. http://dx.doi.org/10.1002/1521-4141(200002) 30:2594::AID-IMMU594 3.0.CO;2-1.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 594-603
    • Lehner, T.1    Bergmeier, L.A.2    Wang, Y.3    Tao, L.4    Sing, M.5    Spallek, R.6    van der Zee, R.7
  • 41
    • 0033537855 scopus 로고    scopus 로고
    • The effect of immunization on chemokines and CCR5 and CXCR4 coreceptor functions in SIV binding and chemotaxis
    • Wang Y, Tao L, Mitchell E, Bergmeier L, Doyle C, Lehner T. 1999. The effect of immunization on chemokines and CCR5 and CXCR4 coreceptor functions in SIV binding and chemotaxis. Vaccine 17:1826-1836. http: //dx.doi.org/10.1016/S0264-410X(98)00482-4.
    • (1999) Vaccine , vol.17 , pp. 1826-1836
    • Wang, Y.1    Tao, L.2    Mitchell, E.3    Bergmeier, L.4    Doyle, C.5    Lehner, T.6
  • 42
    • 33645989497 scopus 로고    scopus 로고
    • T celland B cell-independent adaptive immunity mediated by natural killer cells
    • O'Leary JGM, Goofdarzi M, Drayton DL, von Andrian UH. 2006. T celland B cell-independent adaptive immunity mediated by natural killer cells. Nat. Immunol. 5:507-516. http://dx.doi.org/10.1038/ni1332.
    • (2006) Nat. Immunol. , vol.5 , pp. 507-516
    • O'Leary, J.G.M.1    Goofdarzi, M.2    Drayton, D.L.3    von Andrian, U.H.4
  • 43
    • 32944478316 scopus 로고    scopus 로고
    • Translating innate immunity into immunological memory: implications for vaccine development
    • Pulendran B, Ahmed R. 2006. Translating innate immunity into immunological memory: implications for vaccine development. Cell 124:849-863. http://dx.doi.org/10.1016/j.cell.2006.02.019.
    • (2006) Cell , vol.124 , pp. 849-863
    • Pulendran, B.1    Ahmed, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.