Abnormal response of the proliferation and differentiation of growth plate chondrocytes to melatonin in adolescent idiopathic scoliosis

International Journal of Molecular Sciences

Volumn 15, Issue 9, 2014, Pages 17100-17114

  Wang, William Wei Jun ^a,b   Man, Gene Chi Wai ^b   Wong, Jack Ho ^b   Ng, Tzi Bun ^b   Lee, Kwong Man ^b   Ng, Bobby Kin Wah ^b   Yeung, Hiu Yan ^b   Qiu, Yong ^a,b   Cheng, Jack Chun Yiu ^b  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Antagonist; Chondrocytes; Differentiation; Dysfunction; Growth plate; Idiopathic scoliosis; Melatonin; MT2 receptor; Proliferation

Indexed keywords

4 PHENYL 2 PROPIONAMIDOTETRALIN; ALKALINE PHOSPHATASE; COLLAGEN TYPE 10; COLLAGENASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE RECEPTOR BLOCKING AGENT; HYALURONIDASE; MELATONIN; MELATONIN 2 RECEPTOR; TRANSCRIPTION FACTOR SOX9; TRYPSIN; UNCLASSIFIED DRUG; MESSENGER RNA;

ADOLESCENT; ADOLESCENT IDIOPATHIC SCOLIOSIS; ARTICLE; BONE GROWTH; CARTILAGE CELL; CASE CONTROL STUDY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CHICKEN; CHONDROGENESIS; CLINICAL ARTICLE; COBB ANGLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENCHONDRAL OSSIFICATION; FEMALE; GENE EXPRESSION; GROWTH PLATE CHONDROCYTE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; MALE; MRNA EXPRESSION ASSAY; MTT ASSAY; PINEALECTOMY; REAL TIME POLYMERASE CHAIN REACTION; SKELETON MALFORMATION; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; COMPARATIVE STUDY; DEFICIENCY; DRUG EFFECTS; GENETICS; GROWTH PLATE; METABOLISM; ORTHOPEDIC SURGERY; PATHOLOGY; PRIMARY CELL CULTURE; SCOLIOSIS; SIGNAL TRANSDUCTION; SPINE FUSION;

ADOLESCENT; CASE-CONTROL STUDIES; CELL DIVISION; CELLS, CULTURED; CHONDROCYTES; FEMALE; GROWTH PLATE; GTP-BINDING PROTEINS; HUMANS; MALE; MELATONIN; ORTHOPEDIC PROCEDURES; PRIMARY CELL CULTURE; RECEPTOR, MELATONIN, MT2; RNA, MESSENGER; SCOLIOSIS; SIGNAL TRANSDUCTION; SPINAL FUSION;

EID: 84907882655     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150917100     Document Type: Article

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