Pinealectomy in a broiler chicken model impairs endochondral ossification and induces rapid cancellous bone loss

Spine Journal

Volumn 13, Issue 11, 2013, Pages 1607-1616

  Aota, Yoichi ^a   Terayama, Hayato ^b   Saito, Tomoyuki ^a   Itoh, Masahiro ^b  

^a YOKOHAMA CITY UNIVERSITY HOSPITAL   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Melatonin; Osteopenia; Osteoporosis; Pinealectomy; Scoliosis

Indexed keywords

ADOLESCENT IDIOPATHIC SCOLIOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE GROWTH; BONE MINERALIZATION; BONE REMODELING; BONE TURNOVER; BROILER; CARTILAGE CELL; CARTILAGE MATRIX; CHICKEN MODEL; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; FEMALE; FLUORESCENCE MICROSCOPY; GROWTH PLATE; HATCHING; LEG LENGTHENING; METAPHYSIS; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOID; OSTEOLYSIS; PHAGOCYTOSIS; PILOT STUDY; PINEALECTOMY; PRIORITY JOURNAL; THICKNESS; TRABECULAR BONE; VERTEBRA BODY;

MELATONIN; OSTEOPENIA; OSTEOPOROSIS; PINEALECTOMY; SCOLIOSIS;

ANIMALS; BONE RESORPTION; CHICKENS; CHONDROCYTES; DISEASE MODELS, ANIMAL; OSTEOCLASTS; OSTEOGENESIS; PINEAL GLAND; SCOLIOSIS;

EID: 84889092931     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2013.05.017     Document Type: Article

References (55)

1. J.C. Cheng, and X. Guo Osteoporosis in adolescent idiopathic scoliosis - a primary problem or secondary to the spinal deformity? Spine 22 1997 1716 1721
2. J.C. Cheng, X. Guo, and A.H. Sher Persistent osteopenia in adolescent idiopathic scoliosis - a longitudinal follow-up study Spine 24 1999 1218 1222
3. J.C. Cheng, S.P. Tang, and X. Guo Osteopenia in adolescent idiopathic scoliosis: a histomorphometric study Spine 26 2001 E19 E23
4. C.S. Cheung, W.T. Lee, and Y.K. Tse Generalized osteopenia in adolescent idiopathic scoliosis-association with abnormal pubertal growth, bone turnover, and calcium intake? Spine 31 2006 330 338
5. M. Roth Idiopathic scoliosis from the point of view of the neuroradiologist Neuroradiology 21 1981 133 138
6. R.W. Porter The pathogenesis of idiopathic scoliosis: uncoupled neuro-osseous growth? Eur Spine J 10 2001 473 479
7. W.C. Chu, W.W. Lam, and Y.L. Chan Relative shortening and functional tethering of spinal cord in adolescent idiopathic scoliosis? Study with multiplanar reformat magnetic resonance imaging and somatosensory evoked potential Spine 31 2006 E19 E25
8. W.C. Chu, G.C. Man, and W.W. Lam Morphological and functional electrophysiological evidence of relative spinal cord tethering in adolescent idiopathic scoliosis Spine 33 2008 673 680
9. C.S.K. Cheung, W. Tak Keung Lee, and Y. Kit Tse Abnormal peri-pubertal anthropometric measurements and growth pattern in adolescent idiopathic scoliosis: a study of 598 patients Spine 28 2003 2152 2157
10. J.W. Kouwenhoven, L.W. Bartels, and K.L. Vincken The relation between organ anatomy and pre-existent vertebral rotation in the normal spine: magnetic resonance imaging study in humans with situs inversus totalis Spine 32 2007 1123 1128
11. J.W. Kouwenhoven, and R.M. Castelein The pathogenesis of adolescent idiopathic scoliosis: review of the literature Spine 33 2008 2898 2908
12. M. Thillard Deformations de la colonne vertebrale consecutives a l'epiphysectomie chez le possin [in French] C R Hebd Seances Acad Sci 248 1959 1238 1240
13. M. Machida, J. Dubousset, and Y. Imamura An experimental study in chickens for the pathogenesis of idiopathic scoliosis Spine 18 1993 1609 1615
14. M. Machida, J. Dubousset, and Y. Imamura Role of melatonin deficiency in the development of scoliosis in pinealectomised chickens J Bone Joint Surg Br 77 1995 134 138
15. M. Machida, J. Dubousset, and Y. Imamura Melatonin: a possible role in pathogenesis of adolescent idiopathic scoliosis Spine 21 1996 1147 1152
16. M. Machida, J. Dubousset, and T. Satoh Pathologic mechanism of experimental scoliosis in pinealectomized chickens Spine 26 2001 E385 E391
17. E. Turhan, E. Acaroglu, and G. Bozkurt Unilateral enucleation affects the laterality but not the incidence of scoliosis in pinealectomized chicken Spine 31 2006 133 138
18. C. O'Kelly, X. Wang, and J. Raso The production of scoliosis after pinealectomy in young chickens, rats, and hamsters Spine 24 1999 35 43
19. T. Kanemura, N. Kawakami, and M. Deguchi Natural course of experimental scoliosis in pinealectomized chickens Spine 22 1997 1563 1567
20. H. Yoshihara, N. Kawakami, and Y. Matsuyama A histomorphologic study of scoliosis in pinealectomized chickens Spine 30 2005 2244 2251
21. X. Wang, H. Jiang, and J. Raso Characterization of the scoliosis that develops after pinealectomy in the chicken and comparison with adolescent idiopathic scoliosis in humans Spine 22 1997 2626 2635
22. X. Wang, M. Moreau, and V.J. Raso Changes in serum melatonin levels in response to pinealectomy in the chicken and its correlation with development of scoliosis Spine 23 1998 2377 2382
23. M. Turgut, H.K. Basaloglu, and C. Yenisey Surgical pinealectomy accelerates intervertebral disc degeneration process in chicken Eur Spine J 15 2006 605 612
24. M. Turgut, S. Kaplan, and A.T. Turgut Morphological, stereological and radiological changes in pinealectomized chicken cervical vertebrae J Pineal Res 39 2005 392 399
25. H. Kono, M. Machida, and M. Saito Mechanism of osteoporosis in adolescent idiopathic scoliosis: experimental scoliosis in pinealectomized chickens J Pineal Res 51 2011 387 393
26. C. Coillard, and C.H. Rivard Vertebral deformities and scoliosis Eur Spine J 5 2 1996 91 100
27. S. Mochizuki, Y. Sasao, and S. Isomi Experimental scoliosis and IGF-I in pinealectomized chicken J Jpn Scoliosis Soc 17 2002 3 6 [in Japanese]
28. A.S. Hilibrand, L.C. Blakemore, and R.T. Loder The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis Spine 21 1996 1140 1146
29. A.B. Fagan, D.J. Kennaway, and A.D. Sutherland Total 24-hour melatonin secretion in adolescent idiopathic scoliosis. A case-control study Spine 23 1998 41 46
30. K.M. Bagnall, V.J. Raso, and D.L. Hill Melatonin levels in idiopathic scoliosis. Diurnal and nocturnal serum melatonin levels in girls with adolescent idiopathic scoliosis Spine 21 1996 1974 1978
31. M. Sadat-Ali, I. al-Habdan, and A. al-Othman Adolescent idiopathic scoliosis. Is low melatonin a cause? Joint Bone Spine 67 2000 62 64
32. M. Machida, J. Dubousset, T. Yamada, and J. Kimura Serum melatonin levels in adolescent idiopathic scoliosis prediction and prevention for curve progression-a prospective study J Pineal Res 46 2009 344 348
33. A. Moreau, D.S. Wang, and S. Forget Melatonin signaling dysfunction in adolescent idiopathic scoliosis Spine 29 2004 1772 1781
34. G.C. Man, W.W. Wang, and B.H. Yeung Abnormal proliferation and differentiation of osteoblasts from girls with adolescent idiopathic scoliosis to melatonin J Pineal Res 49 2010 69 77
35. X.S. Qiu, N.L. Tang, and H.Y. Yeung Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis Spine 32 2007 1748 1753
36. I.A. Stokes, H. Spence, and D.D. Aronsson Mechanical modulation of vertebral body growth. Implications for scoliosis progression Spine 21 1996 1162 1167
37. A.B. Fagan, D.J. Kennaway, and A.P. Oakley Pinealectomy in the chicken: a good model of scoliosis? Eur Spine J 18 2009 1154 1159
38. P.C. McCaskey, G.N. Rowland, and R.K. Page Focal failures of endochondral ossification in the broiler Avian Dis 26 1982 701 717
39. H.I. Roach New aspects of endochondral ossification in the chick: chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix J Bone Miner Res 12 1997 795 805
40. C. Barreto, and N.J. Wilsman Hypertrophic chondrocyte volume and growth rates in avian growth plates Res Vet Sci 56 1994 53 61
41. K.M. Cheung, T. Wang, and Y.G. Hu Primary thoracolumbar scoliosis in pinealectomized chickens Spine 28 2003 2499 2504
42. C.T. Brighton Structure and function of growth plate Clin Orthop 136 1978 23 32
43. C. Barreto, R.M. Albrecht, and D.E. Bjorling Evidence of the growth plate and the growth of long bones in juvenile dinosaurs Science 262 1993 2020 2023
44. C.R. Howlett, M. Dickson, and A.K. Sheridan The fine structure of the proximal growth plate of the avian tibia: vascular supply J Anat 139 1984 115 132
45. M. Machida, J. Dubousset, and T. Yamada Experimental scoliosis in melatonin-deficient C57BL/6J mice without pinealectomy J Pineal Res 41 2006 1 7
46. C. Ohlsson, B. Bengtsson, and O.G.P. Isaksson Growth hormone and bone Endocr Rev 19 1998 55 79
47. Z. Ostrowska, B. Kos-Kudla, and E. Swietochowska Influence of pinealectomy and long-term melatonin administration on GH-IGF-I axis function in male rats Neuroendocrinol Lett 22 2001 255 262
48. M.L. Forsling, M.J. Wheeler, and A.J. Williams The effect of melatonin administration on pituitary hormone secretion in man Clin Endocrinol (Oxf) 51 1999 637 642
49. H. Koyama, O. Nakade, and Y. Takada Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation J Bone Miner Res 17 2002 1219 1229
50. E.J. Sánchez-Barceló, M.D. Mediavilla, D.X. Tan, and R.J. Reiter Scientific basis for the potential use of melatonin in bone diseases: osteoporosis and adolescent idiopathic scoliosis J Osteoporos 2010 2010 830231
51. R.J. Reiter, D.-X. Tan, L.C. Manchester, and W. Qi Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence Cell Biochem Biophys 34 2001 237 256
52. J.A. Roth, B.G. Kim, and W.L. Lin Melatonin promotes osteoblast differentiation and bone formation J Biol Chem 274 1999 22041 22047
53. O. Nakade, H. Koyama, and H. Ariji Melatonin stimulates proliferation and type I collagen synthesis in human bone cell in vitro J Pineal Res 27 1999 106 110
54. S.C. Manolagas Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis Endocr Rev 21 2000 115 137
55. N. Suzuki, and A. Hattori Melatonin suppresses osteoclastic and osteoblastic activities in the scales of goldfish J Pineal Res 33 2002 253 258