The diabetes drug target MitoNEET governs a novel trafficking pathway to rebuild an Fe-S cluster into cytosolic aconitase/iron regulatory protein 1

Journal of Biological Chemistry

Volumn 289, Issue 41, 2014, Pages 28070-28086

  Ferecatu, Ioana ^a   Gonçalves, Sergio ^a   Golinelli Cohen, Marie Pierre ^a,g   Clémancey, Martin ^b   Martelli, Alain ^a,c,d,e,f   Riquier, Sylvie ^a   Guittet, Eric ^a   Latour, Jean Marc ^b   Puccio, Hélène ^a,c,e,f   Drapier, Jean Claude ^a   Lescop, Ewen ^a   Bouton, Cécile ^a  

^a CNRS   (France)

^b Laboratoire Biopuces   (France)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSERM   (France)

^e UNIVERSITÉ DE STRASBOURG   (France)

^f l'alimentation et l'Environnement   (France)

^g INSTITUT JACQUES MONOD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MACHINERY; MITOCHONDRIA; PROTEINS; SULFUR;

CELLULAR PATHWAY; CYTOSOLIC ACONITASE; IRON HOMEOSTASIS; IRON REGULATORY PROTEIN 1; IRON-SULFUR CLUSTERS; LIVER REGENERATION; MASTER REGULATORS; REGULATORY PROTEIN;

IRON;

ACONITATE HYDRATASE; ANTIDIABETIC AGENT; HYDROGEN PEROXIDE; IRON; IRON REGULATORY PROTEIN 1; IRON SULFUR PROTEIN; MITOCHONDRIAL PROTEIN; NITRIC OXIDE; PROTEIN ABCB7; PROTEIN ALR; PROTEIN HSC20; PROTEIN MIA40; PROTEIN MITONEET; REGULATOR PROTEIN; SULFUR; UNCLASSIFIED DRUG; CARRIER PROTEIN; CISD1 PROTEIN, HUMAN; IRP1 PROTEIN, HUMAN; MIA40 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LEVEL; CONTROLLED STUDY; CYTOSOL; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR TRANSPORT; IRON BALANCE; IRON STORAGE; LIVER MITOCHONDRION; LIVER REGENERATION; METABOLIC REGULATION; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OUTER MEMBRANE; PROTEIN DEFECT; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; ANIMAL; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; HEPG2 CELL LINE; HOMEOSTASIS; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HELA CELLS; HEP G2 CELLS; HOMEOSTASIS; HUMANS; HYDROGEN PEROXIDE; IRON; IRON REGULATORY PROTEIN 1; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; NITRIC OXIDE; OXIDATION-REDUCTION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84907842409     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.548438     Document Type: Article

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