Polymethyacrylate based microparticulates of insulin for oral delivery: Preparation and in vitro dissolution stability in the presence of enzyme inhibitors

International Journal of Pharmaceutics

Volumn 225, Issue 1-2, 2001, Pages 31-39

  Agarwal, Vikas ^a   Reddy, Indra K ^a   Khan, Mansoor A ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Chicken ovomucoid; Coprecipitates; Dissolution stability; Duck ovomucoid; Inhibitors; Insulin; Microparticulates

Indexed keywords

ALCOHOL; BUFFER; CALCIUM CHLORIDE; CHYMOTRYPSIN; DRUG CARRIER; ENZYME INHIBITOR; HYDROCHLORIC ACID; INSULIN; MICROSPHERE; OVOMUCOID; PHOSPHATE; POLY(METHYL METHACRYLATE); POLYMER; SODIUM SULFATE; TRYPSIN; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; HOMOGENATE; IN VITRO STUDY; MICROENCAPSULATION; PARTICLE SIZE; PH; PRECIPITATION; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CHICKENS; DRUG COMPOUNDING; DRUG STABILITY; DUCKS; HUMANS; INSULIN; OVOMUCIN; TRYPSIN INHIBITORS;

EID: 0035964459     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00740-2     Document Type: Article

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