TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction

International Journal of Molecular Sciences

Volumn 15, Issue 10, 2014, Pages 18362-18380

  Sun, Zewei ^a   Han, Jie ^a   Zhao, Wenting ^a   Zhang, Yuanyuan ^a   Wang, Shuai ^a   Ye, Lifang ^a   Liu, Tingting ^a   Zheng, Liangrong ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Calcium; Ischemia; Mitochondrial; Rat; TRPV1 protein

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CAPSAZEPINE; SUBSTANCE P; SUPEROXIDE; VANILLOID RECEPTOR 1; CALCIUM; SMALL INTERFERING RNA; TRPV1 PROTEIN, MOUSE; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOGENESIS; CALCIUM OVERLOAD; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FLOW CYTOMETRY; GENE DELETION; GENETIC TRANSFECTION; HYPOXIA; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOREACTIVITY; INTOXICATION; MALE; MEMBRANE DEPOLARIZATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL HYPOXIA; CELL LINE; GENE EXPRESSION; GENETICS; HEART; HEART MUSCLE; HEART MUSCLE CELL; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY; REPERFUSION INJURY; RNA INTERFERENCE; UPREGULATION;

RATTUS;

ANIMALS; APOPTOSIS; CALCIUM; CELL HYPOXIA; CELL LINE; GENE DELETION; GENE EXPRESSION; HEART; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRPV CATION CHANNELS; UP-REGULATION;

EID: 84907829577     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151018362     Document Type: Article

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