Metformin protects against gentamicin-induced hair cell death in vitro but not ototoxicity in vivo

Neuroscience Letters

Volumn 583, Issue , 2014, Pages 65-69

  Oishi, Naoki ^a,b   Kendall, Ann ^b   Schacht, Jochen ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Cochlear explants; Gentamicin; Guinea pigs; Metformin; Ototoxicity; Outer hair cells

Indexed keywords

ENDONUCLEASE G; GENTAMICIN; METFORMIN; ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GUINEA PIG; HAIR CELL; HEARING IMPAIRMENT; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; OTOTOXICITY; OUTER HAIR CELL; ANIMAL; CBA MOUSE; DRUG EFFECTS; PATHOLOGY;

ANIMALS; ANTI-BACTERIAL AGENTS; FEMALE; GENTAMICINS; GUINEA PIGS; HAIR CELLS, AUDITORY; HYPOGLYCEMIC AGENTS; IN VITRO TECHNIQUES; MALE; METFORMIN; MICE, INBRED CBA;

EID: 84907772114     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.09.028     Document Type: Article

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