Forms, forces, and stem cell fate

Current Opinion in Cell Biology

Volumn 31, Issue , 2014, Pages 92-97

  Bellas, Evangelia ^a,b   Chen, Christopher S ^a,b  

^a Boston University   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHOGEN;

CELL ADHESION; CELL CONTACT; CELL FATE; CELL SHAPE; CYTOSKELETON; EXTRACELLULAR MATRIX; FORCE; HEALING; MECHANICS; MECHANOTRANSDUCTION; MORPHOGENESIS; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; TISSUE GROWTH; TRANSCRIPTION REGULATION; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; HUMAN; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; CELL SHAPE; CYTOSKELETON; EXTRACELLULAR MATRIX; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MORPHOGENESIS; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84907692927     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2014.09.006     Document Type: Review

References (57)

1. Leptin M., Grunewald B. Cell shape changes during gastrulation in Drosophila. Development 1990, 110:73-84.
2. Thompson D.W. On growth and form 1942, University Press, England, United Kingdom.
3. Heisenberg C.-P., Bellaïche Y. Forces in tissue morphogenesis and patterning. Cell 2013, 153:948-962.
4. Spiegelman B.M., Farmer S.R. Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3 adipocytes. Cell 1982, 29:53-60.
5. Ingber D. Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis. J Cell Biochem 1991, 47:236-241.
6. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126677.
7. McBeath R., Pirone D., Nelson C. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 2004, 6:483-495.
8. Abercrombie M., Heaysman J.E. Observations on the social behaviour of cells in tissue culture. II. Monolayering of fibroblasts. Exp Cell Res 1954, 6:293-306.
9. Abercrombie M., Dunn G.A. Adhesions of fibroblasts to substratum during contact inhibition observed by interference reflection microscopy. Exp Cell Res 1975, 92:57-62.
10. Abbott J. The loss of phenotypic traits by differentiated cells: III. The reversible behavior of chondrocytes in primary cultures. J Cell Biol 1966, 28:473-487.
11. Ross S.E., Hemati N., Longo K.A., Bennett C.N., Lucas P.C., Erickson R.L., MacDougald O.A. Inhibition of adipogenesis by Wnt signaling. Science 2000, 289:950-953.
12. Cadigan K.M., Nusse R. Wnt signaling: a common theme in animal development. Genes Dev 1997, 11:3286-3305.
13. Folkman J., Moscona A. Role of cell shape in growth control. Nature 1978, 273:345-349.
14. Ingber D.E., Folkman J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. J Cell Biol 1989, 109:317-330.
15. Chen C.S., Mrksich M., Huang S., Whitesides G.M., Ingber D.E. Geometric control of cell life and death. Science 1997, 276:1425-1428.
16. Ruiz S.A., Chen C.S. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells 2008, 26:2921-2927.
17. Kilian K.A., Bugarija B., Lahn B.T., Mrksich M. Geometric cues for directing the differentiation of mesenchymal stem cells. Proc Natl Acad Sci U S A 2010, 107:4872-4877.
18. Van Nieuw Amerongen G.P., Beckers C.M.L., Achekar I.D., Zeeman S., Musters R.J.P., van Hinsbergh V.W.M. Involvement of Rho kinase in endothelial barrier maintenance. Arterioscler Thromb Vasc Biol 2007, 27:2332-2339.
19. Braga V.M., Machesky L.M., Hall A., Hotchin N.A. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol 1997, 137:1421-1431.
20. Nelson C.M., Pirone D.M., Tan J.L., Chen C.S. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Mol Biol Cell 2004, 15:2943-2953.
21. Liu W.F., Nelson C.M., Pirone D.M., Chen C.S. E-cadherin engagement stimulates proliferation via Rac1. J Cell Biol 2006, 173:431-441.
22. Braga V.M. Cell-cell adhesion and signalling. Curr Opin Cell Biol 2002, 14:546-556.
23. Ren X.D., Kiosses W.B., Schwartz M.A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J 1999, 18:578-585.
24. Fu J., Wang Y.-K., Yang M.T., Desai R.A., Yu X., Liu Z., Chen C.S. Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nat Methods 2010, 7:733-736.
25. Riveline D., Zamir E., Balaban N.Q., Schwarz U.S., Ishizaki T., Narumiya S., Kam Z., Geiger B., Bershadsky A.D. Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol 2001, 153:1175-1186.
26. Chen C.S., Alonso J.L., Ostuni E., Whitesides G.M., Ingber D.E. Cell shape provides global control of focal adhesion assembly. Biochem Biophys Res Commun 2003, 307:355-361.
27. Pirone D.M., Liu W.F., Ruiz S.A., Gao L., Raghavan S., Lemmon C.A., Romer L.H., Chen C.S. An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling. J Cell Biol 2006, 174:277-288.
28. Schober M., Raghavan S., Nikolova M., Polak L., Pasolli H.A., Beggs H.E., Reichardt L.F., Fuchs E. Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics. J Cell Biol 2007, 176:667-680.
29. Young D.A., Choi Y.S., Engler A.J., Christman K.L. Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue. Biomaterials 2013, 34:8581-8588.
30. Bae Y.H., Mui K.L., Hsu B.Y., Liu S.-L., Cretu A., Razinia Z., Xu T., Puré E., Assoian R.K. A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling. Sci Signal 2014, 7:ra57.
31. Klein E.A., Yin L., Kothapalli D., Castagnino P., Byfield F.J., Xu T., Levental I., Hawthorne E., Janmey P.A., Assoian R.K. Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening. Curr Biol 2009, 19:1511-1518.
32. Trappmann B., Gautrot J.E., Connelly J.T., Strange D.G.T., Li Y., Oyen M.L., Cohen Stuart M.A., Boehm H., Li B., Vogel V., et al. Extracellular-matrix tethering regulates stem-cell fate. Nat Mater 2012, 11:642-649.
33. Gilbert P.M., Havenstrite K.L., Magnusson K.E.G., Sacco A., Leonardi N.A., Kraft P., Nguyen N.K., Thrun S., Lutolf M.P., Blau H.M. Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 2010, 329:1078-1081.
34. Holst J., Watson S., Lord M.S., Eamegdool S.S., Bax D.V., Nivison-Smith L.B., Kondyurin A., Ma L., Oberhauser A.F., Weiss A.S., et al. Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nat Biotechnol 2010, 28:1123-1128.
35. Chowdhury F., Na S., Li D., Poh Y.-C., Tanaka T.S., Wang F., Wang N. Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells. Nat Mater 2010, 9:82-88.
36. Tee S.-Y., Fu J., Chen C.S., Janmey P.A. Cell shape and substrate rigidity both regulate cell stiffness. Biophys J 2011, 100:L25-L27.
37. Cosgrove B.D., Gilbert P.M., Porpiglia E., Mourkioti F., Lee S.P., Corbel S.Y., Llewellyn M.E., Delp S.L., Blau H.M. Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. Nat Med 2014, 20:255-264.
38. Dixon J.E., Shah D.A., Rogers C., Hall S., Weston N., Parmenter C.D.J., McNally D., Denning C., Shakesheff K.M. Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation. Proc Natl Acad Sci USA 2014.
39. Dupont S., Morsut L., Aragona M., Enzo E., Giulitti S., Cordenonsi M., Zanconato F., Le Digabel J., Forcato M., Bicciato S., et al. Role of YAP/TAZ in mechanotransduction. Nature 2011, 474:179-183.
40. Olson E.N., Nordheim A. Linking actin dynamics and gene transcription to drive cellular motile functions. Nat Rev Mol Cell Biol 2010, 11:353-365.
41. Hong J.-H., Hwang E.S., McManus M.T., Amsterdam A., Tian Y., Kalmukova R., Mueller E., Benjamin T., Spiegelman B.M., Sharp P.A., et al. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 2005, 309:1074-1078.
42. Wang D.-Z., Li S., Hockemeyer D., Sutherland L., Wang Z., Schratt G., Richardson J.A., Nordheim A., Olson E.N. Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A 2002, 99:14855-14860.
43. Kuwahara K., Barrientos T., Pipes G.C.T., Li S., Olson E.N. Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol 2005, 25:3173-3181.
44. Tan J.L., Tien J., Pirone D.M., Gray D.S., Bhadriraju K., Chen C.S. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc Natl Acad Sci U S A 2003, 100:1484-1489.
45. Wozniak M.A., Cheng C.Q., Shen C.J., Gao L., Olarerin-George A.O., Won K.-J., Hogenesch J.B., Chen C.S. Adhesion regulates MAP kinase/ternary complex factor exchange to control a proliferative transcriptional switch. Curr Biol 2012, 22:2017-2026.
46. Mammoto A., Huang S., Ingber D.E. Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. J Cell Sci 2007, 120:456-467.
47. Mammoto A., Mammoto T., Ingber D.E. Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci 2012, 125:3061-3073.
48. Mammoto A., Connor K.M., Mammoto T., Yung C.W., Huh D., Aderman C.M., Mostoslavsky G., Smith L.E.H., Ingber D.E. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature 2009, 457:1103-1108.
49. Swift J., Ivanovska I.L., Buxboim A., Harada T., Dingal P.C.D.P., Pinter J., Pajerowski J.D., Spinler K.R., Shin J.-W., Tewari M., et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science 2013, 341:1240104.
50. Ho C.Y., Lammerding J. Lamins at a glance. J Cell Sci 2012, 125:2087-2093.
51. Baker B.M., Chen C.S. Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues. J Cell Sci 2012, 125:3015-3024.
52. Khetan S., Guvendiren M., Legant W.R., Cohen D.M., Chen C.S., Burdick J.A. Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels. Nat Mater 2013, 12:458-465.
53. Yang C., Tibbitt M.W., Basta L., Anseth K.S. Mechanical memory and dosing influence stem cell fate. Nat Mater 2014.
54. Luxenburg C., Pasolli H.A., Williams S.E., Fuchs E. Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat Cell Biol 2011, 13:203-214.
55. Wong V.W., Rustad K.C., Akaishi S., Sorkin M., Glotzbach J.P., Januszyk M., Nelson E.R., Levi K., Paterno J., Vial I.N., et al. Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling. Nat Med 2012, 18:148-152.
56. Gilkes D.M., Xiang L., Lee S.J., Chaturvedi P., Hubbi M.E., Wirtz D., Semenza G.L. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A 2014, 111:E384-E393.
57. Burnette D.T., Shao L., Ott C., Pasapera A.M., Fischer R.S., Baird M.A., Der Loughian C., Delanoe-Ayari H., Paszek M.J., Davidson M.W., et al. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells. J Cell Biol 2014, 205:83-96.