Allopregnanolone and its precursor progesterone do not reduce injury after experimental stroke in hypertensive rats - Role of postoperative temperature regulation?

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Spratt, Neil J ^a,b   Tomkins, Amelia J ^a   Pepperall, Debbie ^a   McLeod, Damian D ^a   Calford, Mike B ^a,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b Drug and Alcohol Clinical Services   (Australia)

^c UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; PROGESTERONE; ELTANOLONE; NEUROPROTECTIVE AGENT;

24 HOUR BEHAVIORAL SCORE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; BODY TEMPERATURE; BODY TEMPERATURE DISORDER; BODY TEMPERATURE MEASUREMENT; BRAIN INFARCTION SIZE; BRAIN INJURY; CONTROLLED STUDY; ENVIRONMENTAL TEMPERATURE; EXPERIMENTAL STROKE; HEMISPHERE; HOMEOTHERMIC HEATING MAT; HYPERTENSION; HYPOTHERMIA; MALE; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; RAT; SCORING SYSTEM; SENSORIMOTOR FUNCTION; SPONTANEOUSLY HYPERTENSIVE RAT; STICKY DOT REMOVAL TEST SCORE; THERMAL REGULATING SYSTEM; THERMOREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; MOTOR ACTIVITY; PATHOPHYSIOLOGY; POSTOPERATIVE PERIOD; TEMPERATURE;

RATTUS;

ANIMALS; BODY TEMPERATURE REGULATION; DISEASE MODELS, ANIMAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MOTOR ACTIVITY; NEUROPROTECTIVE AGENTS; POSTOPERATIVE PERIOD; PREGNANOLONE; PROGESTERONE; RATS; RATS, INBRED SHR; TEMPERATURE;

EID: 84907587757     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107752     Document Type: Article

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