Peroxiredoxin 4 improves insulin biosynthesis and glucoseinduced insulin secretion in insulin-secreting INS-1E cells

Journal of Biological Chemistry

Volumn 289, Issue 39, 2014, Pages 26904-26913

  Mehmeti, Ilir ^a   Lortz, Stephan ^a   Elsner, Matthias ^a   Lenzen, Sigurd ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANES; COVALENT BONDS; CYTOLOGY; ELECTRIC RESISTANCE; GLUCOSE; NUTRIENTS; PHYSIOLOGY; PROTEINS; SULFUR COMPOUNDS;

BENEFICIAL EFFECTS; BIOLOGICAL FUNCTIONS; DISULFIDE BOND FORMATION; ENDOPLASMIC RETICULUM; GLUCOSE-RESPONSIVE; INSULIN RESISTANCE; MRNA TRANSCRIPTION; PROTEIN DISULFIDE ISOMERASES;

INSULIN;

GLUCOSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROGEN PEROXIDE; INSULIN; INSULIN 1; INSULIN 2; MESSENGER RNA; PEROXIREDOXIN 4; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; PEROXIREDOXIN; PRDX4 PROTEIN, HUMAN; SWEETENING AGENT;

ANIMAL TISSUE; ARTICLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; INS 1E CELL LINE; INSULIN RELEASE; INSULIN SYNTHESIS; LYMPHOCYTE PRESERVATION; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PEROXIDATION; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RNA TRANSCRIPTION; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; HEPG2 CELL LINE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; PROTEIN FOLDING; SECRETION (PROCESS);

ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; INSULIN; INSULIN-SECRETING CELLS; OXIDATION-REDUCTION; PEROXIREDOXINS; PROTEIN FOLDING; RNA, MESSENGER; SWEETENING AGENTS; TRANSCRIPTION, GENETIC;

EID: 84907587665     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.568329     Document Type: Article

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