Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

PLoS Pathogens

Volumn 10, Issue 9, 2014, Pages

  Shepardson, Kelly M ^a   Jhingran, Anupam ^b   Caffrey, Alayna ^c   Obar, Joshua J ^c   Suratt, Benjamin T ^d   Berwin, Brent L ^a   Hohl, Tobias M ^b   Cramer, Robert A ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c MONTANA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; MESSENGER RNA; TRIAMCINOLONE ACETONIDE; CXCL1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL MIGRATION ASSAY; CELL SURVIVAL; CFU COUNTING; CONTROLLED STUDY; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FUNGUS CULTURE; HISTOPATHOLOGY; LUNG ASPERGILLOSIS; LUNG LAVAGE; MACROPHAGE; MOUSE; NEUTROPHIL; NONHUMAN; PATHOGEN CLEARANCE; PROTECTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL; WESTERN BLOTTING; XTT ASSAY; ANIMAL; ASPERGILLUS FUMIGATUS; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; ENZYME IMMUNOASSAY; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; LUNG; METABOLISM; MICROBIOLOGY; PULMONARY ASPERGILLOSIS;

ASPERGILLUS FUMIGATUS;

ANIMALS; APOPTOSIS; ASPERGILLUS FUMIGATUS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CXCL1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNITY, INNATE; IMMUNOENZYME TECHNIQUES; INFLAMMATION; LUNG; MACROPHAGES; MICE; MYELOID CELLS; NEUTROPHILS; PULMONARY ASPERGILLOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84907584833     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004378     Document Type: Article

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