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Volumn 9, Issue 9, 2014, Pages

A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a Malaria vaccine candidate

Author keywords

[No Author keywords available]

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; MALARIA VACCINE; RECOMBINANT CIRCUMSPOROZOITE PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; IMMUNOLOGICAL ADJUVANT; PROTOZOAL PROTEIN;

EID: 84907573576     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107764     Document Type: Article
Times cited : (42)

References (62)
  • 1
    • 28444498006 scopus 로고    scopus 로고
    • Available Accessed 7 March 2014
    • WHO (2013) Malaria Fact Sheet. Available: http://www.who.int/mediacentre/factsheets/fs094/en/. Accessed 7 March 2014.
    • (2013) Malaria Fact Sheet
  • 3
    • 0037090258 scopus 로고    scopus 로고
    • Protection of humans against malaria by immunization with radiation-attenuated plasmodium falciparum sporozoites
    • Hoffman SL, Goh LM, Luke T.C., Schneider I., Le TP, et al. (2002) Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J Infect Dis 185: 1155-1164.
    • (2002) J Infect Dis , vol.185 , pp. 1155-1164
    • Hoffman, S.L.1    Goh, L.M.2    Luke, T.C.3    Schneider, I.4    Le, T.P.5
  • 4
    • 68049143479 scopus 로고    scopus 로고
    • Protection against a malaria challenge by sporozoite inoculation
    • Roestenberg M, McCall M, Hopman J., Wiersma J, Luty AJ, et al (2009) Protection against a malaria challenge by sporozoite inoculation. N Engl J Med 361: 468-477.
    • (2009) N Engl J Med , vol.361 , pp. 468-477
    • Roestenberg, M.1    McCall, M.2    Hopman, J.3    Wiersma, J.4    Luty, A.J.5
  • 5
    • 33845884017 scopus 로고    scopus 로고
    • The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites
    • Kumar KA, Sano G, Boscardin S., Nussenzweig RS, Nussenzweig MC, et al. (2006) The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites. Nature 444: 937-940.
    • (2006) Nature , vol.444 , pp. 937-940
    • Kumar, K.A.1    Sano, G.2    Boscardin, S.3    Nussenzweig, R.S.4    Nussenzweig, M.C.5
  • 6
    • 80052760900 scopus 로고    scopus 로고
    • Sterile protective immunity to malaria is associated with a panel of novel P. Falciparum antigens
    • 007948
    • Trieu A, Kayala MA, Burk C, Molina D.M., Freilich DA, et al. (2011) Sterile protective immunity to malaria is associated with a panel of novel P. falciparum antigens. Mol Cell Proteomics 10: M111 007948.
    • (2011) Mol Cell Proteomics , vol.10 , pp. M111
    • Trieu, A.1    Kayala, M.A.2    Burk, C.3    Molina, D.M.4    Freilich, D.A.5
  • 7
    • 0036510624 scopus 로고    scopus 로고
    • Binding and invasion of liver cells by plasmodium falciparum sporozoites. Essential involvement of the amino terminus of circumsporozoite protein
    • Rathore D, Sacci JB, de la Vega P, McCutchan TF (2002) Binding and invasion of liver cells by Plasmodium falciparum sporozoites. Essential involvement of the amino terminus of circumsporozoite protein. J Biol Chem 277: 7092-7098.
    • (2002) J Biol Chem , vol.277 , pp. 7092-7098
    • Rathore, D.1    Sacci, J.B.2    De La Vega, P.3    McCutchan, T.F.4
  • 8
    • 0031202831 scopus 로고    scopus 로고
    • Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: Identification of a universal T cell epitope in the plasmodium falciparum circumsporozoite protein
    • Calvo-Calle J.M., Hammer J, Sinigaglia F., Clavijo P, Moya-Castro ZR, et al. (1997) Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein. J Immunol 159: 1362-1373.
    • (1997) J Immunol , vol.159 , pp. 1362-1373
    • Calvo-Calle, J.M.1    Hammer, J.2    Sinigaglia, F.3    Clavijo, P.4    Moya-Castro, Z.R.5
  • 9
    • 0030747677 scopus 로고    scopus 로고
    • Degenerate cytotoxic T cell epitopes from P. Falciparum restricted by multiple HLA - A and HLA - B supertype alleles
    • Doolan DL, Hoffman SL, Southwood S, Wentworth P.A., Sidney J., et al. (1997) Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity 7: 97-112.
    • (1997) Immunity , vol.7 , pp. 97-112
    • Doolan, D.L.1    Hoffman, S.L.2    Southwood, S.3    Wentworth, P.A.4    Sidney, J.5
  • 10
    • 12344299732 scopus 로고    scopus 로고
    • The plasmodium circumsporozoite protein is proteolytically processed during cell invasion
    • Coppi A, Pinzon-Ortiz C, Hutter C., Sinnis P. (2005) The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion. J Exp Med 201: 27-33.
    • (2005) J Exp Med , vol.201 , pp. 27-33
    • Coppi, A.1    Pinzon-Ortiz, C.2    Hutter, C.3    Sinnis, P.4
  • 11
    • 68949088019 scopus 로고    scopus 로고
    • The development of the RTS, S malaria vaccine candidate: Challenges and lessons
    • Ballou WR (2009) The development of the RTS, S malaria vaccine candidate: challenges and lessons. Parasite Immunol 31: 492-500.
    • (2009) Parasite Immunol , vol.31 , pp. 492-500
    • Ballou, W.R.1
  • 12
    • 0025099759 scopus 로고
    • Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria
    • Tam JP, Clavijo P, Lu Y.A., Nussenzweig V., Nussenzweig R, et al. (1990) Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. J Exp Med 171: 299-306.
    • (1990) J Exp Med , vol.171 , pp. 299-306
    • Tam, J.P.1    Clavijo, P.2    Lu, Y.A.3    Nussenzweig, V.4    Nussenzweig, R.5
  • 13
    • 0018891152 scopus 로고
    • Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite
    • Yoshida N, Nussenzweig RS, Potocnjak P, Nussenzweig V., Aikawa M. (1980) Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite. Science 207: 71-73.
    • (1980) Science , vol.207 , pp. 71-73
    • Yoshida, N.1    Nussenzweig, R.S.2    Potocnjak, P.3    Nussenzweig, V.4    Aikawa, M.5
  • 14
    • 0023622196 scopus 로고
    • Synthetic peptide vaccine confers protection against murine malaria
    • Zavala F, Tam JP, Barr P.J., Romero PJ, Ley V, et al. (1987) Synthetic peptide vaccine confers protection against murine malaria. J Exp Med 166: 1591-1596.
    • (1987) J Exp Med , vol.166 , pp. 1591-1596
    • Zavala, F.1    Tam, J.P.2    Barr, P.J.3    Romero, P.J.4    Ley, V.5
  • 15
    • 4344577124 scopus 로고    scopus 로고
    • Conquering the intolerable burden of malaria: What's new, what's needed: A summary
    • Breman JG, Alilio MS, Mills A. (2004) Conquering the intolerable burden of malaria: what's new, what's needed: a summary. Am J Trop Med Hyg 71: 1-15.
    • (2004) Am J Trop Med Hyg , vol.71 , pp. 1-15
    • Breman, J.G.1    Alilio, M.S.2    Mills, A.3
  • 16
    • 0015699215 scopus 로고
    • Immunization of man against sporozite-induced falciparum malaria
    • Clyde DF, Most H, McCarthy V.C., Vanderberg J.P. (1973) Immunization of man against sporozite-induced falciparum malaria. Am J Med Sci 266: 169-177.
    • (1973) Am J Med Sci , vol.266 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.C.3    Vanderberg, J.P.4
  • 17
    • 0032977856 scopus 로고    scopus 로고
    • Immunity to non-cerebral severe malaria is acquired after one or two infections
    • Gupta S, Snow RW, Donnelly C.A., Marsh K., Newbold C. (1999) Immunity to non-cerebral severe malaria is acquired after one or two infections. Nat Med 5: 340-343.
    • (1999) Nat Med , vol.5 , pp. 340-343
    • Gupta, S.1    Snow, R.W.2    Donnelly, C.A.3    Marsh, K.4    Newbold, C.5
  • 18
    • 67049086871 scopus 로고    scopus 로고
    • Heterologous prime-boost vaccination
    • Lu S (2009) Heterologous prime-boost vaccination. Curr Opin Immunol 21: 346-351.
    • (2009) Curr Opin Immunol , vol.21 , pp. 346-351
    • Lu, S.1
  • 19
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei
    • Nussenzweig RS, Vanderberg J, Most H., Orton C. (1967) Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei. Nature 216: 160-162.
    • (1967) Nature , vol.216 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 20
    • 0025743461 scopus 로고
    • In vitro activity of CD4+ and CD8+ T lymphocytes from mice immunized with a synthetic malaria peptide
    • Renia L, Marussig MS, Grillot D, Pied S., Corradin G, et al. (1991) In vitro activity of CD4+ and CD8+ T lymphocytes from mice immunized with a synthetic malaria peptide. Proc Natl Acad Sci U S A 88: 7963-7967.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7963-7967
    • Renia, L.1    Marussig, M.S.2    Grillot, D.3    Pied, S.4    Corradin, G.5
  • 21
    • 0018593563 scopus 로고
    • Use of attenuated sporozoites in the immunization of human volunteers against falciparum malaria
    • Rieckmann KH, Beaudoin RL, Cassells J.S., Sell K.W. (1979) Use of attenuated sporozoites in the immunization of human volunteers against falciparum malaria. Bull World Health Organ 57 Suppl 1: 261-265.
    • (1979) Bull World Health Organ , vol.57 , pp. 261-265
    • Rieckmann, K.H.1    Beaudoin, R.L.2    Cassells, J.S.3    Sell, K.W.4
  • 22
    • 0027361805 scopus 로고
    • The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria
    • Rodrigues M, Nussenzweig RS, Zavala F. (1993) The relative contribution of antibodies, CD4+ and CD8+ T cells to sporozoite-induced protection against malaria. Immunology 80: 1-5.
    • (1993) Immunology , vol.80 , pp. 1-5
    • Rodrigues, M.1    Nussenzweig, R.S.2    Zavala, F.3
  • 23
    • 15044338866 scopus 로고    scopus 로고
    • The global distribution of clinical episodes of plasmodium falciparum malaria
    • Snow RW, Guerra CA, Noor A.M., Myint HY, Hay S.I. (2005) The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434: 214-217.
    • (2005) Nature , vol.434 , pp. 214-217
    • Snow, R.W.1    Guerra, C.A.2    Noor, A.M.3    Myint, H.Y.4    Hay, S.I.5
  • 25
    • 57249094204 scopus 로고    scopus 로고
    • The N-terminal domain of plasmodium falciparum circumsporozoite protein represents a target of protective immunity
    • Bongfen SE, Ntsama PM, Offner S, Smith T., Felger I, et al. (2009) The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity. Vaccine 27: 328-335.
    • (2009) Vaccine , vol.27 , pp. 328-335
    • Bongfen, S.E.1    Ntsama, P.M.2    Offner, S.3    Smith, T.4    Felger, I.5
  • 26
    • 0021934252 scopus 로고
    • Conserved group-specific epitopes of the circumsporozoite proteins revealed by antibodies to synthetic peptides
    • Vergara U, Ruiz A, Ferreira A., Nussenzweig RS, Nussenzweig V. (1985) Conserved group-specific epitopes of the circumsporozoite proteins revealed by antibodies to synthetic peptides. J Immunol 134: 3445-3448.
    • (1985) J Immunol , vol.134 , pp. 3445-3448
    • Vergara, U.1    Ruiz, A.2    Ferreira, A.3    Nussenzweig, R.S.4    Nussenzweig, V.5
  • 27
    • 84874721348 scopus 로고    scopus 로고
    • Full-length plasmodium falciparum circumsporozoite protein administered with long-chain poly(I.C) or the toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice
    • Kastenmuller K, Espinosa DA, Trager L, Stoyanov C., Salazar AM, et al. (2013) Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I.C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice. Infect Immun 81: 789-800.
    • (2013) Infect Immun , vol.81 , pp. 789-800
    • Kastenmuller, K.1    Espinosa, D.A.2    Trager, L.3    Stoyanov, C.4    Salazar, A.M.5
  • 28
    • 70350353195 scopus 로고    scopus 로고
    • Structure of the plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate
    • Plassmeyer ML, Reiter K, Shimp R.L., Jr., Kotova S, Smith PD, et al. (2009) Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate. J Biol Chem 284: 26951-26963.
    • (2009) J Biol Chem , vol.284 , pp. 26951-26963
    • Plassmeyer, M.L.1    Reiter, K.2    Shimp, R.L.3    Kotova, S.4    Smith, P.D.5
  • 29
    • 29644442359 scopus 로고    scopus 로고
    • Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against plasmodium yoelii in mice
    • Ophorst OJ, Radosevic K, Havenga M.J., Pau MG, Holterman L, et al. (2006) Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice. Infect Immun 74: 313-320.
    • (2006) Infect Immun , vol.74 , pp. 313-320
    • Ophorst, O.J.1    Radosevic, K.2    Havenga, M.J.3    Pau, M.G.4    Holterman, L.5
  • 30
  • 31
    • 78149457931 scopus 로고    scopus 로고
    • A synthetic adjuvant to enhance and expand immune responses to influenza vaccines
    • Coler RN, Baldwin SL, Shaverdian N, Bertholet S., Reed SJ, et al. (2010) A synthetic adjuvant to enhance and expand immune responses to influenza vaccines. PLoS One 5: e13677.
    • (2010) PLoS One , vol.5 , pp. e13677
    • Coler, R.N.1    Baldwin, S.L.2    Shaverdian, N.3    Bertholet, S.4    Reed, S.J.5
  • 32
    • 84861204189 scopus 로고    scopus 로고
    • KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. Major transmitted by its natural vector Phlebotomus duboscqi
    • Gomes R, Teixeira C, Oliveira F., Lawyer PG, Elnaiem DE, et al. (2012) KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. major transmitted by its natural vector Phlebotomus duboscqi. PLoS Negl Trop Dis 6: e1610.
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. e1610
    • Gomes, R.1    Teixeira, C.2    Oliveira, F.3    Lawyer, P.G.4    Elnaiem, D.E.5
  • 33
    • 80053582764 scopus 로고    scopus 로고
    • Protection of mice from mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate
    • Windish HP, Duthie MS, Misquith A, Ireton G., Lucas E, et al. (2011) Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate. Vaccine 29: 7842-7848.
    • (2011) Vaccine , vol.29 , pp. 7842-7848
    • Windish, H.P.1    Duthie, M.S.2    Misquith, A.3    Ireton, G.4    Lucas, E.5
  • 34
    • 77957841735 scopus 로고    scopus 로고
    • Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice
    • Shiratsuchi T, Rai U, Krause A., Worgall S, Tsuji M. (2010) Replacing adenoviral vector HVR1 with a malaria B cell epitope improves immunogenicity and circumvents preexisting immunity to adenovirus in mice. J Clin Invest 120: 3688-3701.
    • (2010) J Clin Invest , vol.120 , pp. 3688-3701
    • Shiratsuchi, T.1    Rai, U.2    Krause, A.3    Worgall, S.4    Tsuji, M.5
  • 35
    • 0026519706 scopus 로고
    • Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160
    • Hu SL, Abrams K, Barber G.N., Moran P., Zarling JM, et al. (1992) Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science 255: 456-459.
    • (1992) Science , vol.255 , pp. 456-459
    • Hu, S.L.1    Abrams, K.2    Barber, G.N.3    Moran, P.4    Zarling, J.M.5
  • 36
    • 33751071573 scopus 로고    scopus 로고
    • Combination DNA plus protein HIV vaccines
    • Lu S (2006) Combination DNA plus protein HIV vaccines. Springer Semin Immunopathol 28: 255-265.
    • (2006) Springer Semin Immunopathol , vol.28 , pp. 255-265
    • Lu, S.1
  • 37
    • 84861480702 scopus 로고    scopus 로고
    • Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant bacillus calmette-guerin expressing the plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice
    • Arama C, Assefaw-Redda Y, Rodriguez A., Fernandez C, Corradin G, et al (2012) Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guerin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice. Vaccine 30: 4040-4045.
    • (2012) Vaccine , vol.30 , pp. 4040-4045
    • Arama, C.1    Assefaw-Redda, Y.2    Rodriguez, A.3    Fernandez, C.4    Corradin, G.5
  • 38
    • 0027292880 scopus 로고
    • Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria
    • Li S, Rodrigues M, Rodriguez D., Rodriguez JR, Esteban M, et al. (1993) Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria. Proc Natl Acad Sci U S A 90: 5214-5218.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5214-5218
    • Li, S.1    Rodrigues, M.2    Rodriguez, D.3    Rodriguez, J.R.4    Esteban, M.5
  • 39
    • 34247476084 scopus 로고    scopus 로고
    • Viral vector vaccines make memory T cells against malaria
    • Reyes-Sandoval A., Harty JT, Todryk S.M. (2007) Viral vector vaccines make memory T cells against malaria. Immunology 121: 158-165.
    • (2007) Immunology , vol.121 , pp. 158-165
    • Reyes-Sandoval, A.1    Harty, J.T.2    Todryk, S.M.3
  • 40
    • 43249109767 scopus 로고    scopus 로고
    • Adenovirus 5 and 35 vectors expressing plasmodium falciparum circumspor-ozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice
    • Shott JP, McGrath SM, Pau M.G., Custers JH, Ophorst O, et al. (2008) Adenovirus 5 and 35 vectors expressing Plasmodium falciparum circumspor-ozoite surface protein elicit potent antigen-specific cellular IFN-gamma and antibody responses in mice. Vaccine 26: 2818-2823.
    • (2008) Vaccine , vol.26 , pp. 2818-2823
    • Shott, J.P.1    McGrath, S.M.2    Pau, M.G.3    Custers, J.H.4    Ophorst, O.5
  • 42
    • 0031065201 scopus 로고    scopus 로고
    • Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cellmediated protective immunity against malaria
    • Rodrigues EG, Zavala F, Eichinger D., Wilson JM, Tsuji M. (1997) Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cellmediated protective immunity against malaria. J Immunol 158: 1268-1274.
    • (1997) J Immunol , vol.158 , pp. 1268-1274
    • Rodrigues, E.G.1    Zavala, F.2    Eichinger, D.3    Wilson, J.M.4    Tsuji, M.5
  • 43
    • 34248329578 scopus 로고    scopus 로고
    • Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS, S/AS01B boosting significantly improves immunogenicity to plasmodium falciparum CS compared to that with either malaria vaccine alone
    • Stewart VA, McGrath SM, Dubois P.M., Pau MG, Mettens P, et al. (2007) Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS, S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone. Infect Immun 75: 2283-2290.
    • (2007) Infect Immun , vol.75 , pp. 2283-2290
    • Stewart, V.A.1    McGrath, S.M.2    Dubois, P.M.3    Pau, M.G.4    Mettens, P.5
  • 44
    • 84893059821 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults
    • Creech CB, Dekker CL, Ho D, Phillips S., Mackey S, et al. (2013) Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults. Hum Vaccin Immunother 9: 2548-2557.
    • (2013) Hum Vaccin Immunother , vol.9 , pp. 2548-2557
    • Creech, C.B.1    Dekker, C.L.2    Ho, D.3    Phillips, S.4    Mackey, S.5
  • 45
    • 84864542615 scopus 로고    scopus 로고
    • A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults
    • Keefer MC, Gilmour J, Hayes P., Gill D, Kopycinski J, et al (2012) A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults. PLoS One 7: e41936.
    • (2012) PLoS One , vol.7 , pp. e41936
    • Keefer, M.C.1    Gilmour, J.2    Hayes, P.3    Gill, D.4    Kopycinski, J.5
  • 46
    • 84892948089 scopus 로고    scopus 로고
    • A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in burkinabe healthy adults 18 to 45 years of age
    • Ouedraogo A, Tiono AB, Kargougou D, Yaro J.B., Ouedraogo E., et al. (2013) A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age. PLoS One 8: e78679.
    • (2013) PLoS One , vol.8 , pp. e78679
    • Ouedraogo, A.1    Tiono, A.B.2    Kargougou, D.3    Yaro, J.B.4    Ouedraogo, E.5
  • 47
    • 0242658726 scopus 로고    scopus 로고
    • Prime-boost strategies for malaria vaccine development
    • Dunachie SJ, Hill A.V. (2003) Prime-boost strategies for malaria vaccine development. J Exp Biol 206: 3771-3779.
    • (2003) J Exp Biol , vol.206 , pp. 3771-3779
    • Dunachie, S.J.1    Hill, A.V.2
  • 48
    • 0025693889 scopus 로고
    • The circumsporozoite protein of plasmodium: A mechanism of immune evasion by the malaria parasite?
    • Schofield L (1990) The circumsporozoite protein of Plasmodium: a mechanism of immune evasion by the malaria parasite? Bull World Health Organ 68 Suppl: 66-73.
    • (1990) Bull World Health Organ , vol.68 , pp. 66-73
    • Schofield, L.1
  • 49
    • 35848931896 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans provide a signal to plasmodium sporozoites to stop migrating and productively invade host cells
    • Coppi A, Tewari R, Bishop J.R., Bennett BL, Lawrence R, et al. (2007) Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells. Cell Host Microbe 2: 316-327.
    • (2007) Cell Host Microbe , vol.2 , pp. 316-327
    • Coppi, A.1    Tewari, R.2    Bishop, J.R.3    Bennett, B.L.4    Lawrence, R.5
  • 50
    • 5644228594 scopus 로고    scopus 로고
    • Efficacy of the RTS, S/AS02A vaccine against plasmodium falciparum infection and disease in young african children: Randomised controlled trial
    • Alonso PL, Sacarlal J, Aponte J.J., Leach A., Macete E, et al. (2004) Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 364: 1411-1420.
    • (2004) Lancet , vol.364 , pp. 1411-1420
    • Alonso, P.L.1    Sacarlal, J.2    Aponte, J.J.3    Leach, A.4    Macete, E.5
  • 51
    • 80053236891 scopus 로고    scopus 로고
    • Safety and efficacy of the RTS, S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial
    • Asante KP, Abdulla S, Agnandji S., Lyimo J, Vekemans J, et al (2011) Safety and efficacy of the RTS, S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial. Lancet Infect Dis 11: 741-749.
    • (2011) Lancet Infect Dis , vol.11 , pp. 741-749
    • Asante, K.P.1    Abdulla, S.2    Agnandji, S.3    Lyimo, J.4    Vekemans, J.5
  • 52
    • 84871666296 scopus 로고    scopus 로고
    • A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS, S/AS01E
    • Ndungu FM, Mwacharo J, Kimani D., Kai O, Moris P, et al (2012) A statistical interaction between circumsporozoite protein-specific T cell and antibody responses and risk of clinical malaria episodes following vaccination with RTS, S/AS01E. PLoS One 7: e52870.
    • (2012) PLoS One , vol.7 , pp. e52870
    • Ndungu, F.M.1    Mwacharo, J.2    Kimani, D.3    Kai, O.4    Moris, P.5
  • 53
    • 84867239659 scopus 로고    scopus 로고
    • Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines
    • Fox CB, Baldwin SL, Vedvick T.S., Angov E., Reed S.G. (2012) Effects on immunogenicity by formulations of emulsion-based adjuvants for malaria vaccines. Clin Vaccine Immunol 19: 1633-1640.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 1633-1640
    • Fox, C.B.1    Baldwin, S.L.2    Vedvick, T.S.3    Angov, E.4    Reed, S.G.5
  • 54
    • 84855890988 scopus 로고    scopus 로고
    • GLASE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults
    • Behzad H, Huckriede AL, Haynes L, Gentleman B., Coyle K, et al. (2012) GLASE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults. J Infect Dis 205: 466-473.
    • (2012) J Infect Dis , vol.205 , pp. 466-473
    • Behzad, H.1    Huckriede, A.L.2    Haynes, L.3    Gentleman, B.4    Coyle, K.5
  • 55
    • 84886950936 scopus 로고    scopus 로고
    • Evaluation of safety and immunogenicity of recombinant influenza hemagglutinin (H5/Indonesia/05/2005) formulated with and without a stable oil-in-water emulsion containing glucopyranosyl-lipid A (SE+GLA) adjuvant
    • Treanor JJ, Essink B, Hull S., Reed S, Izikson R, et al (2013) Evaluation of safety and immunogenicity of recombinant influenza hemagglutinin (H5/Indonesia/05/2005) formulated with and without a stable oil-in-water emulsion containing glucopyranosyl-lipid A (SE+GLA) adjuvant. Vaccine 31: 5760-5765.
    • (2013) Vaccine , vol.31 , pp. 5760-5765
    • Treanor, J.J.1    Essink, B.2    Hull, S.3    Reed, S.4    Izikson, R.5
  • 56
    • 78449248099 scopus 로고    scopus 로고
    • The th1 immune response to plasmodium falciparum circumsporozoite protein is boosted by adenovirus vectors 35 and 26 with a homologous insert
    • Radosevic K, Rodriguez A, Lemckert A.A., van der Meer M, Gillissen G, et al. (2010) The Th1 immune response to Plasmodium falciparum circumsporozoite protein is boosted by adenovirus vectors 35 and 26 with a homologous insert. Clin Vaccine Immunol 17: 1687-1694.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 1687-1694
    • Radosevic, K.1    Rodriguez, A.2    Lemckert, A.A.3    Van Der Meer, M.4    Gillissen, G.5
  • 57
    • 84883427666 scopus 로고    scopus 로고
    • Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells
    • Baldwin SL, Ching LK, Pine S.O., Moutaftsi M., Lucas E, et al. (2013) Protection against tuberculosis with homologous or heterologous protein/vector vaccine approaches is not dependent on CD8+ T cells. J Immunol 191: 2514-2525.
    • (2013) J Immunol , vol.191 , pp. 2514-2525
    • Baldwin, S.L.1    Ching, L.K.2    Pine, S.O.3    Moutaftsi, M.4    Lucas, E.5
  • 58
    • 80355145782 scopus 로고    scopus 로고
    • Reliable protein production in a pseudomonas fluorescens expression system
    • Retallack DM, Jin H, Chew L. (2012) Reliable protein production in a Pseudomonas fluorescens expression system. Protein Expr Purif 81: 157-165.
    • (2012) Protein Expr Purif , vol.81 , pp. 157-165
    • Retallack, D.M.1    Jin, H.2    Chew, L.3
  • 60
    • 84863304598 scopus 로고    scopus 로고
    • Vienna, Austria. Available Accessed 11 March 2013
    • R Core Team (2012) R: A language and environment for statistical computing. Vienna, Austria. Available: http://www.r-project.org/. Accessed 11 March 2013.
    • (2012) R: A Language and Environment for Statistical Computing
  • 61
    • 0037114136 scopus 로고    scopus 로고
    • Cutting edge: A new tool to evaluate human pre-erythrocytic malaria vaccines: Rodent parasites bearing a hybrid plasmodium falciparum circumsporozoite protein
    • Persson C, Oliveira GA, Sultan A.A., Bhanot P., Nussenzweig V, et al. (2002) Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein. J Immunol 169: 6681-6685.
    • (2002) J Immunol , vol.169 , pp. 6681-6685
    • Persson, C.1    Oliveira, G.A.2    Sultan, A.A.3    Bhanot, P.4    Nussenzweig, V.5
  • 62
    • 0034795312 scopus 로고    scopus 로고
    • Detection of malaria liver-stages in mice infected through the bite of a single anopheles mosquito using a highly sensitive real-time PCR
    • Bruna-Romero O., Hafalla JC, Gonzalez-Aseguinolaza G, Sano G., Tsuji M, et al. (2001) Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR. Int J Parasitol 31: 1499-1502.
    • (2001) Int J Parasitol , vol.31 , pp. 1499-1502
    • Bruna-Romero, O.1    Hafalla, J.C.2    Gonzalez-Aseguinolaza, G.3    Sano, G.4    Tsuji, M.5


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