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Volumn 8, Issue 9, 2014, Pages

IL-10 and NOS2 Modulate Antigen-Specific Reactivity and Nerve Infiltration by T Cells in Experimental Leprosy

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOFERRITIN; EOTAXIN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; ML0380; ML1877; ML2028; MONOCYTE CHEMOTACTIC PROTEIN 1; PEPTIDES AND PROTEINS; RANTES; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; NOS2 PROTEIN, MOUSE;

EID: 84907572371     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003149     Document Type: Article
Times cited : (11)

References (70)
  • 2
    • 55449096172 scopus 로고    scopus 로고
    • Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis
    • Duthie MS, Ireton GC, Kanaujia GV, Goto W, Liang H, et al. (2008) Selection of antigens and development of prototype tests for point-of-care leprosy diagnosis. Clin Vaccine Immunol 15: 1590–1597.
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1590-1597
    • Duthie, M.S.1    Ireton, G.C.2    Kanaujia, G.V.3    Goto, W.4    Liang, H.5
  • 3
    • 61949447837 scopus 로고    scopus 로고
    • From genome-based in silico predictions to ex vivo verification of leprosy diagnosis
    • Geluk A, Spencer JS, Bobosha K, Pessolani MC, Pereira GM, et al. (2009) From genome-based in silico predictions to ex vivo verification of leprosy diagnosis. Clin Vaccine Immunol 16: 352–359.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 352-359
    • Geluk, A.1    Spencer, J.S.2    Bobosha, K.3    Pessolani, M.C.4    Pereira, G.M.5
  • 4
    • 84861122390 scopus 로고    scopus 로고
    • New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy
    • Geluk A, Bobosha K, van der Ploeg-van Schip JJ, Spencer JS, Banu S, et al. (2012) New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy. J Immunol 188: 4782–4791.
    • (2012) J Immunol , vol.188 , pp. 4782-4791
    • Geluk, A.1    Bobosha, K.2    Van Der Ploeg-Van Schip, J.J.3    Spencer, J.S.4    Banu, S.5
  • 5
    • 84855900191 scopus 로고    scopus 로고
    • Development of a mouse food pad model for detection of sub clinical leprosy
    • Lahiri R, Randhawa B, Franken KL, Duthie MS, Spencer JS, et al. (2011) Development of a mouse food pad model for detection of sub clinical leprosy. Lepr Rev 82: 432–444.
    • (2011) Lepr Rev , vol.82 , pp. 432-444
    • Lahiri, R.1    Randhawa, B.2    Franken, K.L.3    Duthie, M.S.4    Spencer, J.S.5
  • 6
    • 84855910297 scopus 로고    scopus 로고
    • Cytokine responses to Mycobacterium leprae unique proteins differentiate between Mycobacterium leprae infected and naive armadillos
    • Pena M, Geluk A, Van Der Ploeg-Van Schip JJ, Franken KL, Sharma R, et al. (2011) Cytokine responses to Mycobacterium leprae unique proteins differentiate between Mycobacterium leprae infected and naive armadillos. Lepr Rev 82: 422–431.
    • (2011) Lepr Rev , vol.82 , pp. 422-431
    • Pena, M.1    Geluk, A.2    Van Der Ploeg-Van Schip, J.J.3    Franken, K.L.4    Sharma, R.5
  • 7
    • 78951478557 scopus 로고    scopus 로고
    • Immunologically reactive M. leprae antigens with relevance to diagnosis and vaccine development
    • Sampaio LH, Stefani MM, Oliveira RM, Sousa AL, Ireton GC, et al. (2011) Immunologically reactive M. leprae antigens with relevance to diagnosis and vaccine development. BMC Infect Dis 11: 26.
    • (2011) BMC Infect Dis , vol.11 , pp. 26
    • Sampaio, L.H.1    Stefani, M.M.2    Oliveira, R.M.3    Sousa, A.L.4    Ireton, G.C.5
  • 8
    • 29144456599 scopus 로고    scopus 로고
    • Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy
    • Spencer JS, Dockrell HM, Kim HJ, Marques MA, Williams DL, et al. (2005) Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy. J Immunol 175: 7930–7938.
    • (2005) J Immunol , vol.175 , pp. 7930-7938
    • Spencer, J.S.1    Dockrell, H.M.2    Kim, H.J.3    Marques, M.A.4    Williams, D.L.5
  • 9
    • 79551469515 scopus 로고    scopus 로고
    • Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy
    • Spencer JS, Kim HJ, Wheat WH, Chatterjee D, Balagon MV, et al. (2011) Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy. Clin Vaccine Immunol 18: 260–267.
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 260-267
    • Spencer, J.S.1    Kim, H.J.2    Wheat, W.H.3    Chatterjee, D.4    Balagon, M.V.5
  • 10
    • 84871495234 scopus 로고    scopus 로고
    • Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy
    • Spencer JS, Duthie MS, Geluk A, Balagon MF, Kim HJ, et al. (2012) Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy. Mem Inst Oswaldo Cruz 107 Suppl 1: 79–89.
    • (2012) Mem Inst Oswaldo Cruz , vol.107 Suppl 1 , pp. 79-89
    • Spencer, J.S.1    Duthie, M.S.2    Geluk, A.3    Balagon, M.F.4    Kim, H.J.5
  • 12
    • 0034491977 scopus 로고    scopus 로고
    • Exploitation of gene knockout mice models to study the pathogenesis of leprosy
    • Krahenbuhl J, Adams LB, (2000) Exploitation of gene knockout mice models to study the pathogenesis of leprosy. Lepr Rev 71 Suppl: S170–175.
    • (2000) Lepr Rev , vol.71 Suppl , pp. S170-175
    • Krahenbuhl, J.1    Adams, L.B.2
  • 13
    • 0037083232 scopus 로고    scopus 로고
    • The study of Mycobacterium leprae infection in interferon-gamma gene–disrupted mice as a model to explore the immunopathologic spectrum of leprosy
    • Adams LB, Scollard DM, Ray NA, Cooper AM, Frank AA, et al. (2002) The study of Mycobacterium leprae infection in interferon-gamma gene–disrupted mice as a model to explore the immunopathologic spectrum of leprosy. J Infect Dis 185 Suppl 1: S1–8.
    • (2002) J Infect Dis , vol.185 Suppl 1 , pp. S1-8
    • Adams, L.B.1    Scollard, D.M.2    Ray, N.A.3    Cooper, A.M.4    Frank, A.A.5
  • 14
    • 34548549377 scopus 로고    scopus 로고
    • Emergence of an effective adaptive cell mediated immune response to Mycobacterium leprae is not impaired in reactive oxygen intermediate-deficient mice
    • Hagge DA, Marks VT, Ray NA, Dietrich MA, Kearney MT, et al. (2007) Emergence of an effective adaptive cell mediated immune response to Mycobacterium leprae is not impaired in reactive oxygen intermediate-deficient mice. FEMS Immunol Med Microbiol 51: 92–101.
    • (2007) FEMS Immunol Med Microbiol , vol.51 , pp. 92-101
    • Hagge, D.A.1    Marks, V.T.2    Ray, N.A.3    Dietrich, M.A.4    Kearney, M.T.5
  • 15
    • 65349093399 scopus 로고    scopus 로고
    • Lymphotoxin-alpha and TNF have essential but independent roles in the evolution of the granulomatous response in experimental leprosy
    • Hagge DA, Saunders BM, Ebenezer GJ, Ray NA, Marks VT, et al. (2009) Lymphotoxin-alpha and TNF have essential but independent roles in the evolution of the granulomatous response in experimental leprosy. Am J Pathol 174: 1379–1389.
    • (2009) Am J Pathol , vol.174 , pp. 1379-1389
    • Hagge, D.A.1    Saunders, B.M.2    Ebenezer, G.J.3    Ray, N.A.4    Marks, V.T.5
  • 16
    • 84871478190 scopus 로고    scopus 로고
    • Insights from animal models on the immunogenetics of leprosy: a review
    • Adams LB, Pena MT, Sharma R, Hagge DA, Schurr E, et al. (2012) Insights from animal models on the immunogenetics of leprosy: a review. Mem Inst Oswaldo Cruz 107 Suppl 1: 197–208.
    • (2012) Mem Inst Oswaldo Cruz , vol.107 Suppl 1 , pp. 197-208
    • Adams, L.B.1    Pena, M.T.2    Sharma, R.3    Hagge, D.A.4    Schurr, E.5
  • 17
    • 0033850077 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in resistance to Mycobacterium leprae in mice
    • Adams LB, Job CK, Krahenbuhl JL, (2000) Role of inducible nitric oxide synthase in resistance to Mycobacterium leprae in mice. Infect Immun 68: 5462–5465.
    • (2000) Infect Immun , vol.68 , pp. 5462-5465
    • Adams, L.B.1    Job, C.K.2    Krahenbuhl, J.L.3
  • 19
    • 67349185555 scopus 로고    scopus 로고
    • Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil
    • Franceschi DS, Mazini PS, Rudnick CC, Sell AM, Tsuneto LT, et al. (2009) Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil. Int J Infect Dis 13: 493–498.
    • (2009) Int J Infect Dis , vol.13 , pp. 493-498
    • Franceschi, D.S.1    Mazini, P.S.2    Rudnick, C.C.3    Sell, A.M.4    Tsuneto, L.T.5
  • 20
    • 27944475604 scopus 로고    scopus 로고
    • IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy
    • Malhotra D, Darvishi K, Sood S, Sharma S, Grover C, et al. (2005) IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy. Hum Genet 118: 295–300.
    • (2005) Hum Genet , vol.118 , pp. 295-300
    • Malhotra, D.1    Darvishi, K.2    Sood, S.3    Sharma, S.4    Grover, C.5
  • 21
    • 61849147420 scopus 로고    scopus 로고
    • Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for -819C/T in leprosy susceptibility
    • Pereira AC, Brito-de-Souza VN, Cardoso CC, Dias-Baptista IM, Parelli FP, et al. (2009) Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for -819C/T in leprosy susceptibility. Genes Immun 10: 174–180.
    • (2009) Genes Immun , vol.10 , pp. 174-180
    • Pereira, A.C.1    Brito-De-Souza, V.N.2    Cardoso, C.C.3    Dias-Baptista, I.M.4    Parelli, F.P.5
  • 22
    • 0036890977 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha and interleukin-10 promoter gene polymorphisms in leprosy
    • Santos AR, Suffys PN, Vanderborght PR, Moraes MO, Vieira LM, et al. (2002) Role of tumor necrosis factor-alpha and interleukin-10 promoter gene polymorphisms in leprosy. J Infect Dis 186: 1687–1691.
    • (2002) J Infect Dis , vol.186 , pp. 1687-1691
    • Santos, A.R.1    Suffys, P.N.2    Vanderborght, P.R.3    Moraes, M.O.4    Vieira, L.M.5
  • 23
    • 84886739722 scopus 로고    scopus 로고
    • Association of cytokine gene polymorphism with susceptibility and clinical types of leprosy
    • Settin A, Nassar S, Abdel-Latif A, Elbaz R, El-Mongy S, et al. (2007) Association of cytokine gene polymorphism with susceptibility and clinical types of leprosy. Int J Health Sci (Qassim) 1: 25–33.
    • (2007) Int J Health Sci (Qassim) , vol.1 , pp. 25-33
    • Settin, A.1    Nassar, S.2    Abdel-Latif, A.3    Elbaz, R.4    El-Mongy, S.5
  • 24
    • 84869835896 scopus 로고    scopus 로고
    • IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample
    • Cardona-Castro N, Sanchez-Jimenez M, Rojas W, Bedoya-Berrio G, (2012) IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample. Biomedica 32: 71–76.
    • (2012) Biomedica , vol.32 , pp. 71-76
    • Cardona-Castro, N.1    Sanchez-Jimenez, M.2    Rojas, W.3    Bedoya-Berrio, G.4
  • 25
    • 80052877834 scopus 로고    scopus 로고
    • Genetic variations and interactions in anti-inflammatory cytokine pathway genes in the outcome of leprosy: a study conducted on a MassARRAY platform
    • Aggarwal S, Ali S, Chopra R, Srivastava A, Kalaiarasan P, et al. (2011) Genetic variations and interactions in anti-inflammatory cytokine pathway genes in the outcome of leprosy: a study conducted on a MassARRAY platform. J Infect Dis 204: 1264–1273.
    • (2011) J Infect Dis , vol.204 , pp. 1264-1273
    • Aggarwal, S.1    Ali, S.2    Chopra, R.3    Srivastava, A.4    Kalaiarasan, P.5
  • 26
    • 0031773310 scopus 로고    scopus 로고
    • Lepromatous leprosy patients show T helper 1-like cytokine profile with differential expression of interleukin-10 during type 1 and 2 reactions
    • Sreenivasan P, Misra RS, Wilfred D, Nath I, (1998) Lepromatous leprosy patients show T helper 1-like cytokine profile with differential expression of interleukin-10 during type 1 and 2 reactions. Immunology 95: 529–536.
    • (1998) Immunology , vol.95 , pp. 529-536
    • Sreenivasan, P.1    Misra, R.S.2    Wilfred, D.3    Nath, I.4
  • 27
    • 0036094299 scopus 로고    scopus 로고
    • High levels of inflammatory cytokines are associated with poor clinical response to steroid treatment and recurrent episodes of type 1 reactions in leprosy
    • Manandhar R, Shrestha N, Butlin CR, Roche PW, (2002) High levels of inflammatory cytokines are associated with poor clinical response to steroid treatment and recurrent episodes of type 1 reactions in leprosy. Clin Exp Immunol 128: 333–338.
    • (2002) Clin Exp Immunol , vol.128 , pp. 333-338
    • Manandhar, R.1    Shrestha, N.2    Butlin, C.R.3    Roche, P.W.4
  • 29
    • 4043156257 scopus 로고    scopus 로고
    • Differential production of interleukin-10 and interleukin-12 in mononuclear cells from leprosy patients with a Toll-like receptor 2 mutation
    • Kang TJ, Yeum CE, Kim BC, You EY, Chae GT, (2004) Differential production of interleukin-10 and interleukin-12 in mononuclear cells from leprosy patients with a Toll-like receptor 2 mutation. Immunology 112: 674–680.
    • (2004) Immunology , vol.112 , pp. 674-680
    • Kang, T.J.1    Yeum, C.E.2    Kim, B.C.3    You, E.Y.4    Chae, G.T.5
  • 30
    • 84879883329 scopus 로고    scopus 로고
    • Influence of Intron II microsatellite polymorphism in human toll-like receptor 2 gene in leprosy
    • Suryadevara NC, Neela VS, Devalraju KP, Jain S, SivaSai KS, et al. (2013) Influence of Intron II microsatellite polymorphism in human toll-like receptor 2 gene in leprosy. Hum Immunol 74: 1034–1040.
    • (2013) Hum Immunol , vol.74 , pp. 1034-1040
    • Suryadevara, N.C.1    Neela, V.S.2    Devalraju, K.P.3    Jain, S.4    Sivasai, K.S.5
  • 31
    • 84878528770 scopus 로고    scopus 로고
    • Toll-like receptor 1 N248S single-nucleotide polymorphism is associated with leprosy risk and regulates immune activation during mycobacterial infection
    • Marques CS, Brito-de-Souza VN, Guerreiro LT, Martins JH, Amaral EP, et al. (2013) Toll-like receptor 1 N248S single-nucleotide polymorphism is associated with leprosy risk and regulates immune activation during mycobacterial infection. J Infect Dis 208: 120–129.
    • (2013) J Infect Dis , vol.208 , pp. 120-129
    • Marques, C.S.1    Brito-De-Souza, V.N.2    Guerreiro, L.T.3    Martins, J.H.4    Amaral, E.P.5
  • 33
    • 14544304131 scopus 로고    scopus 로고
    • Application of a viability-staining method for Mycobacterium leprae derived from the athymic (nu/nu) mouse foot pad
    • Lahiri R, Randhawa B, Krahenbuhl J, (2005) Application of a viability-staining method for Mycobacterium leprae derived from the athymic (nu/nu) mouse foot pad. J Med Microbiol 54: 235–242.
    • (2005) J Med Microbiol , vol.54 , pp. 235-242
    • Lahiri, R.1    Randhawa, B.2    Krahenbuhl, J.3
  • 34
    • 67650079043 scopus 로고    scopus 로고
    • Molecular determination of Mycobacterium leprae viability by use of real-time PCR
    • Martinez AN, Lahiri R, Pittman TL, Scollard D, Truman R, et al. (2009) Molecular determination of Mycobacterium leprae viability by use of real-time PCR. J Clin Microbiol 47: 2124–2130.
    • (2009) J Clin Microbiol , vol.47 , pp. 2124-2130
    • Martinez, A.N.1    Lahiri, R.2    Pittman, T.L.3    Scollard, D.4    Truman, R.5
  • 35
    • 84883390318 scopus 로고    scopus 로고
    • Molecular assays for determining Mycobacterium leprae viability in tissues of experimentally infected mice
    • Davis GL, Ray NA, Lahiri R, Gillis TP, Krahenbuhl JL, et al. (2013) Molecular assays for determining Mycobacterium leprae viability in tissues of experimentally infected mice. PLoS Negl Trop Dis 7: e2404.
    • (2013) PLoS Negl Trop Dis , vol.7 , pp. e2404
    • Davis, G.L.1    Ray, N.A.2    Lahiri, R.3    Gillis, T.P.4    Krahenbuhl, J.L.5
  • 37
    • 2942595991 scopus 로고    scopus 로고
    • An in vitro model for the lepromatous leprosy granuloma: fate of Mycobacterium leprae from target macrophages after interaction with normal and activated effector macrophages
    • Hagge DA, Ray NA, Krahenbuhl JL, Adams LB, (2004) An in vitro model for the lepromatous leprosy granuloma: fate of Mycobacterium leprae from target macrophages after interaction with normal and activated effector macrophages. J Immunol 172: 7771–7779.
    • (2004) J Immunol , vol.172 , pp. 7771-7779
    • Hagge, D.A.1    Ray, N.A.2    Krahenbuhl, J.L.3    Adams, L.B.4
  • 38
    • 0031007903 scopus 로고    scopus 로고
    • Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
    • Belisle JT, Vissa VD, Sievert T, Takayama K, Brennan PJ, et al. (1997) Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis. Science 276: 1420–1422.
    • (1997) Science , vol.276 , pp. 1420-1422
    • Belisle, J.T.1    Vissa, V.D.2    Sievert, T.3    Takayama, K.4    Brennan, P.J.5
  • 40
    • 0026527762 scopus 로고
    • A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein
    • Mehra V, Bloom BR, Bajardi AC, Grisso CL, Sieling PA, et al. (1992) A major T cell antigen of Mycobacterium leprae is a 10-kD heat-shock cognate protein. J Exp Med 175: 275–284.
    • (1992) J Exp Med , vol.175 , pp. 275-284
    • Mehra, V.1    Bloom, B.R.2    Bajardi, A.C.3    Grisso, C.L.4    Sieling, P.A.5
  • 41
    • 0028298234 scopus 로고
    • Purification, characterization, gene sequence, and significance of a bacterioferritin from Mycobacterium leprae
    • Pessolani MC, Smith DR, Rivoire B, McCormick J, Hefta SA, et al. (1994) Purification, characterization, gene sequence, and significance of a bacterioferritin from Mycobacterium leprae. J Exp Med 180: 319–327.
    • (1994) J Exp Med , vol.180 , pp. 319-327
    • Pessolani, M.C.1    Smith, D.R.2    Rivoire, B.3    McCormick, J.4    Hefta, S.A.5
  • 42
  • 43
    • 10644282122 scopus 로고    scopus 로고
    • Cytolytic CD8+ T cells recognizing CFP10 are recruited to the lung after Mycobacterium tuberculosis infection
    • Kamath AB, Woodworth J, Xiong X, Taylor C, Weng Y, et al. (2004) Cytolytic CD8+ T cells recognizing CFP10 are recruited to the lung after Mycobacterium tuberculosis infection. J Exp Med 200: 1479–1489.
    • (2004) J Exp Med , vol.200 , pp. 1479-1489
    • Kamath, A.B.1    Woodworth, J.2    Xiong, X.3    Taylor, C.4    Weng, Y.5
  • 44
    • 56449097710 scopus 로고    scopus 로고
    • The biology of nerve injury in leprosy
    • Scollard DM, (2008) The biology of nerve injury in leprosy. Lepr Rev 79: 242–253.
    • (2008) Lepr Rev , vol.79 , pp. 242-253
    • Scollard, D.M.1
  • 45
    • 19844376773 scopus 로고    scopus 로고
    • Challenges presented by nerve damage in leprosy
    • Harboe M, Aseffa A, Leekassa R, (2005) Challenges presented by nerve damage in leprosy. Lepr Rev 76: 5–13.
    • (2005) Lepr Rev , vol.76 , pp. 5-13
    • Harboe, M.1    Aseffa, A.2    Leekassa, R.3
  • 46
    • 0035873044 scopus 로고    scopus 로고
    • Mycobacterium leprae-specific, HLA class II-restricted killing of human Schwann cells by CD4+ Th1 cells: a novel immunopathogenic mechanism of nerve damage in leprosy
    • Spierings E, de Boer T, Wieles B, Adams LB, Marani E, et al. (2001) Mycobacterium leprae-specific, HLA class II-restricted killing of human Schwann cells by CD4+ Th1 cells: a novel immunopathogenic mechanism of nerve damage in leprosy. J Immunol 166: 5883–5888.
    • (2001) J Immunol , vol.166 , pp. 5883-5888
    • Spierings, E.1    De Boer, T.2    Wieles, B.3    Adams, L.B.4    Marani, E.5
  • 47
    • 0026095666 scopus 로고
    • Defining protective responses to pathogens: cytokine profiles in leprosy lesions
    • Yamamura M, Uyemura K, Deans RJ, Weinberg K, Rea TH, et al. (1991) Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 254: 277–279.
    • (1991) Science , vol.254 , pp. 277-279
    • Yamamura, M.1    Uyemura, K.2    Deans, R.J.3    Weinberg, K.4    Rea, T.H.5
  • 48
    • 79957466881 scopus 로고    scopus 로고
    • In vitro and skin lesion cytokine profile in Brazilian patients with borderline tuberculoid and borderline lepromatous leprosy
    • Venturini J, Soares CT, Belone Ade F, Barreto JA, Ura S, et al. (2011) In vitro and skin lesion cytokine profile in Brazilian patients with borderline tuberculoid and borderline lepromatous leprosy. Lepr Rev 82: 25–35.
    • (2011) Lepr Rev , vol.82 , pp. 25-35
    • Venturini, J.1    Soares, C.T.2    Belone Ade, F.3    Barreto, J.A.4    Ura, S.5
  • 49
    • 84861833373 scopus 로고    scopus 로고
    • Increased expression of regulatory T cells and down-regulatory molecules in lepromatous leprosy
    • Palermo ML, Pagliari C, Trindade MA, Yamashitafuji TM, Duarte AJ, et al. (2012) Increased expression of regulatory T cells and down-regulatory molecules in lepromatous leprosy. Am J Trop Med Hyg 86: 878–883.
    • (2012) Am J Trop Med Hyg , vol.86 , pp. 878-883
    • Palermo, M.L.1    Pagliari, C.2    Trindade, M.A.3    Yamashitafuji, T.M.4    Duarte, A.J.5
  • 50
    • 84875425732 scopus 로고    scopus 로고
    • Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses
    • Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, et al. (2013) Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 339: 1448–1453.
    • (2013) Science , vol.339 , pp. 1448-1453
    • Teles, R.M.1    Graeber, T.G.2    Krutzik, S.R.3    Montoya, D.4    Schenk, M.5
  • 51
    • 72649097644 scopus 로고    scopus 로고
    • Divergence of macrophage phagocytic and antimicrobial programs in leprosy
    • Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, et al. (2009) Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe 6: 343–353.
    • (2009) Cell Host Microbe , vol.6 , pp. 343-353
    • Montoya, D.1    Cruz, D.2    Teles, R.M.3    Lee, D.J.4    Ochoa, M.T.5
  • 52
    • 0027232912 scopus 로고
    • Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy
    • Sieling PA, Abrams JS, Yamamura M, Salgame P, Bloom BR, et al. (1993) Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy. J Immunol 150: 5501–5510.
    • (1993) J Immunol , vol.150 , pp. 5501-5510
    • Sieling, P.A.1    Abrams, J.S.2    Yamamura, M.3    Salgame, P.4    Bloom, B.R.5
  • 53
    • 0029560642 scopus 로고
    • 2 are associated with the absence of Th 1 cells and in vitro T cell suppression in lepromatous leprosy
    • Misra N, Selvakumar M, Singh S, Bharadwaj M, Ramesh V, et al. (1995) Monocyte derived IL 10 and PGE2 are associated with the absence of Th 1 cells and in vitro T cell suppression in lepromatous leprosy. Immunol Lett 48: 123–128.
    • (1995) Immunol Lett , vol.48 , pp. 123-128
    • Misra, N.1    Selvakumar, M.2    Singh, S.3    Bharadwaj, M.4    Ramesh, V.5
  • 54
    • 0034003429 scopus 로고    scopus 로고
    • Immunological cytokine correlates of protective immunity and pathogenesis in leprosy
    • Lima MC, Pereira GM, Rumjanek FD, Gomes HM, Duppre N, et al. (2000) Immunological cytokine correlates of protective immunity and pathogenesis in leprosy. Scand J Immunol 51: 419–428.
    • (2000) Scand J Immunol , vol.51 , pp. 419-428
    • Lima, M.C.1    Pereira, G.M.2    Rumjanek, F.D.3    Gomes, H.M.4    Duppre, N.5
  • 57
    • 0142010630 scopus 로고    scopus 로고
    • In situ type 1 cytokine gene expression and mechanisms associated with early leprosy progression
    • Stefani MM, Martelli CM, Gillis TP, Krahenbuhl JL, (2003) In situ type 1 cytokine gene expression and mechanisms associated with early leprosy progression. J Infect Dis 188: 1024–1031.
    • (2003) J Infect Dis , vol.188 , pp. 1024-1031
    • Stefani, M.M.1    Martelli, C.M.2    Gillis, T.P.3    Krahenbuhl, J.L.4
  • 58
    • 35348947980 scopus 로고    scopus 로고
    • Serum levels of interferon-gamma, tumour necrosis factor-alpha, soluble interleukin-6R and soluble cell activation markers for monitoring response to treatment of leprosy reactions
    • Iyer A, Hatta M, Usman R, Luiten S, Oskam L, et al. (2007) Serum levels of interferon-gamma, tumour necrosis factor-alpha, soluble interleukin-6R and soluble cell activation markers for monitoring response to treatment of leprosy reactions. Clin Exp Immunol 150: 210–216.
    • (2007) Clin Exp Immunol , vol.150 , pp. 210-216
    • Iyer, A.1    Hatta, M.2    Usman, R.3    Luiten, S.4    Oskam, L.5
  • 59
    • 0033048886 scopus 로고    scopus 로고
    • Increased antimycobacterial immunity in interleukin-10-deficient mice
    • Murray PJ, Young RA, (1999) Increased antimycobacterial immunity in interleukin-10-deficient mice. Infect Immun 67: 3087–3095.
    • (1999) Infect Immun , vol.67 , pp. 3087-3095
    • Murray, P.J.1    Young, R.A.2
  • 60
    • 0033854068 scopus 로고    scopus 로고
    • Increased resistance to mycobacterial infection in the absence of interleukin-10
    • Jacobs M, Brown N, Allie N, Gulert R, Ryffel B, (2000) Increased resistance to mycobacterial infection in the absence of interleukin-10. Immunology 100: 494–501.
    • (2000) Immunology , vol.100 , pp. 494-501
    • Jacobs, M.1    Brown, N.2    Allie, N.3    Gulert, R.4    Ryffel, B.5
  • 61
    • 0036406106 scopus 로고    scopus 로고
    • Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice
    • Jacobs M, Fick L, Allie N, Brown N, Ryffel B, (2002) Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice. Clin Chem Lab Med 40: 893–902.
    • (2002) Clin Chem Lab Med , vol.40 , pp. 893-902
    • Jacobs, M.1    Fick, L.2    Allie, N.3    Brown, N.4    Ryffel, B.5
  • 62
    • 77955385939 scopus 로고    scopus 로고
    • Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung
    • Redford PS, Boonstra A, Read S, Pitt J, Graham C, et al. (2010) Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol 40: 2200–2210.
    • (2010) Eur J Immunol , vol.40 , pp. 2200-2210
    • Redford, P.S.1    Boonstra, A.2    Read, S.3    Pitt, J.4    Graham, C.5
  • 63
    • 61649094923 scopus 로고    scopus 로고
    • Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection
    • Higgins DM, Sanchez-Campillo J, Rosas-Taraco AG, Lee EJ, Orme IM, et al. (2009) Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection. Tuberculosis (Edinb) 89: 149–157.
    • (2009) Tuberculosis (Edinb) , vol.89 , pp. 149-157
    • Higgins, D.M.1    Sanchez-Campillo, J.2    Rosas-Taraco, A.G.3    Lee, E.J.4    Orme, I.M.5
  • 64
    • 0345593709 scopus 로고    scopus 로고
    • Improved clearance of Mycobacterium avium upon disruption of the inducible nitric oxide synthase gene
    • Gomes MS, Florido M, Pais TF, Appelberg R, (1999) Improved clearance of Mycobacterium avium upon disruption of the inducible nitric oxide synthase gene. J Immunol 162: 6734–6739.
    • (1999) J Immunol , vol.162 , pp. 6734-6739
    • Gomes, M.S.1    Florido, M.2    Pais, T.F.3    Appelberg, R.4
  • 65
    • 0032722476 scopus 로고    scopus 로고
    • NOS2-derived nitric oxide regulates the size, quantity and quality of granuloma formation in Mycobacterium avium-infected mice without affecting bacterial loads
    • Ehlers S, Kutsch S, Benini J, Cooper A, Hahn C, et al. (1999) NOS2-derived nitric oxide regulates the size, quantity and quality of granuloma formation in Mycobacterium avium-infected mice without affecting bacterial loads. Immunology 98: 313–323.
    • (1999) Immunology , vol.98 , pp. 313-323
    • Ehlers, S.1    Kutsch, S.2    Benini, J.3    Cooper, A.4    Hahn, C.5
  • 66
    • 33845690070 scopus 로고    scopus 로고
    • Age is an important risk factor for onset and sequelae of reversal reactions in Vietnamese patients with leprosy
    • Ranque B, Nguyen VT, Vu HT, Nguyen TH, Nguyen NB, et al. (2007) Age is an important risk factor for onset and sequelae of reversal reactions in Vietnamese patients with leprosy. Clin Infect Dis 44: 33–40.
    • (2007) Clin Infect Dis , vol.44 , pp. 33-40
    • Ranque, B.1    Nguyen, V.T.2    Vu, H.T.3    Nguyen, T.H.4    Nguyen, N.B.5
  • 67
    • 84886875658 scopus 로고    scopus 로고
    • Identification of clinical, epidemiological and laboratory risk factors for leprosy reactions during and after multidrug therapy
    • Antunes DE, Araujo S, Ferreira GP, Cunha AC, Costa AV, et al. (2013) Identification of clinical, epidemiological and laboratory risk factors for leprosy reactions during and after multidrug therapy. Mem Inst Oswaldo Cruz 108: 901–908.
    • (2013) Mem Inst Oswaldo Cruz , vol.108 , pp. 901-908
    • Antunes, D.E.1    Araujo, S.2    Ferreira, G.P.3    Cunha, A.C.4    Costa, A.V.5
  • 69
    • 34948857581 scopus 로고    scopus 로고
    • Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis
    • Xolalpa W, Vallecillo AJ, Lara M, Mendoza-Hernandez G, Comini M, et al. (2007) Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis. Proteomics 7: 3332–3341.
    • (2007) Proteomics , vol.7 , pp. 3332-3341
    • Xolalpa, W.1    Vallecillo, A.J.2    Lara, M.3    Mendoza-Hernandez, G.4    Comini, M.5
  • 70
    • 12944325306 scopus 로고    scopus 로고
    • Bacterial metastasis: the host plasminogen system in bacterial invasion
    • Lahteenmaki K, Edelman S, Korhonen TK, (2005) Bacterial metastasis: the host plasminogen system in bacterial invasion. Trends Microbiol 13: 79–85.
    • (2005) Trends Microbiol , vol.13 , pp. 79-85
    • Lahteenmaki, K.1    Edelman, S.2    Korhonen, T.K.3


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