Exploitation of gene knockout mice models to study the pathogenesis of leprosy

Leprosy Review

Volumn 71, Issue SUPPL., 2000, Pages

  Krahenbuhl, J ^a   Adams, L B ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; FATTY ACID; GAMMA INTERFERON; INDOMETACIN; N(G) METHYLARGININE; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE SYNTHASE; NITROGEN DERIVATIVE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; IMMUNOPATHOLOGY; KNOCKOUT GENE; LEPROSY; MOUSE; MYCOBACTERIUM LEPRAE; NONHUMAN; PATHOGENESIS; PROSTAGLANDIN RELEASE; SCID MOUSE;

EID: 0034491977     PISSN: 03057518     EISSN: None     Source Type: Journal    
DOI: 10.5935/0305-7518.20000090     Document Type: Conference Paper

References (23)

1. The experimental disease that follows the injection of human leprosy bacilli into footpads of mice
2. Enhanced susceptibility of thymectomised and irradiated mice to infection with M. leprae
3. Effect of neonatal thymectomy and anti-lymphocyte serum on susceptibility of rats to M. leprae
4. The nude mouse in studies of leprosy
5. Infection of the congenitally athymic rat with Mycobacterium leprae
6. Susceptibility of severe combined immunodeficient mice to Mycobacterium leprae: Multiplication of the bacillus and dissemination of the infection at early stage
7. Leprosy
8. The interaction between the macrophage and the leprosy bacillus
9. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus
10. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
11. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death
12. L-arginine dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae
13. Comparison of the roles of reactive oxygen and nitrogen intermediates in the host response to Mycobacterium tuberculosis using transgenic mice
14. Disseminated tuberculosis in interferon-γ gene disrupted mice
15. Role of inducible nitric oxide synthase in resistance to Mycobacterium leprae in mice
16. Learning from lesions: Patterns of tissue inflammation in leprosy
17. Animal models of tuberculosis
18. Identification of nitric oxide synthase as a protective locus against tuberculosis
19. 2 production and cell mediated immunity in a mouse model of leprosy
20. Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis
21. High-output nitric oxide: Weapon against infection?
22. The inducing role of tumor necrosis factor in the development of bacterial granulomas during BCG infection
23. Exacerbation of acute and chronic murine tuberculosis by administration of a TNF receptor-expressing adenovirus