IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals

Journal of Immunology

Volumn 193, Issue 8, 2014, Pages 3992-4001

  Walsh, Matthew C ^a   Pearce, Erika L ^a   Cejas, Pedro J ^a   Lee, Jangeun ^a   Wang, Li San ^a   Choi, Yongwon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 7; PHOSPHATIDYLINOSITOL 3 KINASE; T LYMPHOCYTE RECEPTOR; CD28 ANTIGEN; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; RAG-1 PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CELL TRANSFER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD28; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; HOMEODOMAIN PROTEINS; INTERLEUKIN-18; INTERLEUKIN-7; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOPENIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-18; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; UP-REGULATION;

EID: 84907495015     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400396     Document Type: Article

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