Mimicking homeostatic proliferation in vitro generates T cells with high anti-tumor function in non-lymphopenic hosts

Cancer Immunology, Immunotherapy

Volumn 62, Issue 3, 2013, Pages 503-515

  Kaiser, Andrew D ^a   Gadiot, Jules ^a   Guislain, Aurelie ^a   Blank, Christian U ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

Author keywords

Homeostatic proliferation; Memory like phenotype; T cell; Tumor immunotherapy

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 7; PROTEIN P14; RAG2 PROTEIN; CD28 ANTIGEN; CD3 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; EFFECTOR CELL; FIBROBLAST; HOMEOSTASIS; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; 129 MOUSE; ADOPTIVE IMMUNOTHERAPY; ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTOPENIA; METHODOLOGY; NEOPLASM; T LYMPHOCYTE SUBPOPULATION; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD3; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; DENDRITIC CELLS; HOMEOSTASIS; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY, ADOPTIVE; LYMPHOCYTE ACTIVATION; LYMPHOPENIA; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; NEOPLASMS; T-LYMPHOCYTE SUBSETS;

MLCS; MLOWN;

EID: 84877157822     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-012-1350-1     Document Type: Article

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